| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YER014W | HEM14 | SGDID:S000000816 | lkcE |
lkcE |
Streptomyces rochei | 6f32_a | Q83X90 | 98.50 | 1.60E-11 | 2.30E-15 | 109.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | cgoX hemY |
Coproporphyrinogen III oxidase (EC 1.3.3.15) |
1.3.3.15 | Myxococcus xanthus | 2ivd_a | P56601 | 99.60 | 2.60E-20 | 3.70E-24 | 168.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | OXLA |
L-amino-acid oxidase (LAO) (MPV-LAAO) (EC 1.4.3.2) |
1.4.3.2 | Calloselasma rhodostoma | 2iid_d | P81382 | 97.70 | 1.80E-08 | 2.40E-12 | 91.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | glf Cj1439c |
glf Cj1439c |
5.4.99.9 | Campylobacter jejuni | 4mo2_a | Q0P8H5 | 98.90 | 1.40E-13 | 1.90E-17 | 120.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | rfbD |
UDP-galactopyranose mutase (UGM) (EC 5.4.99.9) (UDP-GALP mutase) (Uridine 5-diphosphate galactopyranose mutase) |
5.4.99.9 | Klebsiella pneumoniae | 2bi8_a | Q48485 | 97.60 | 2.40E-08 | 3.20E-12 | 89.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | Tc00.1047053507993.160 |
Tc00.1047053507993.160 |
Trypanosoma cruzi | 4dsg_a | Q4E1W2 | 98.70 | 2.00E-12 | 2.70E-16 | 118.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | glf glfA |
glf glfA |
5.4.99.9 | Neosartorya fumigata | 3ukl_h | Q4W1X2 | 98.70 | 2.40E-12 | 3.30E-16 | 118.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | LBA0649 |
LBA0649 |
Lactobacillus acidophilus | 4ia5_b | Q5FL96 | 97.40 | 7.90E-08 | 1.00E-11 | 91.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | PPA1039 cbac_05640 |
PPA1039 cbac_05640 |
Cutibacterium acnes | 2b9w_a | Q6A8X5 | 98.80 | 4.80E-13 | 6.90E-17 | 117.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | glf DIP2203 |
glf DIP2203 |
5.4.99.9 | Corynebacterium diphtheriae | 4xgk_a | Q6NER4 | 98.40 | 5.80E-11 | 8.00E-15 | 104.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | PPOX |
Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) |
1.3.3.4 | Homo sapiens | Erythrasma,Hypertrichosis,Migraine With Or Without Aura 1,Phototoxic Dermatitis,Constipation,Porphyria,Cutaneous Porphyria,Acute Porphyria,Proliferative Vasculopathy And Hydranencephaly-Hydrocephaly Syndrome,Deficiency Anemia,Porphyria, Acute Intermittent,Porphyria Cutanea Tarda,Variegate Porphyria,Coproporphyria, Hereditary,Protoporphyria, Erythropoietic, 1,Photoparoxysmal Response 1,Fazio-Londe Disease |
3nks_a | P50336 | ENSG00000143224 | PPOX | 99.40 | 4.50E-18 | 6.50E-22 | 153.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER014W | HEM14 | SGDID:S000000816 | Paox Pao |
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase) |
1.5.3.13 | Mus musculus | 5mbx_a | Q8C0L6 | 97.90 | 3.20E-09 | 4.20E-13 | 97.70 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | PF3D7_1242800 |
PF3D7_1242800 |
Plasmodium falciparum | 3p1w_a | Q8I501 | 99.00 | 1.70E-14 | 2.30E-18 | 132.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | MM_2493 |
MM_2493 |
Methanosarcina mazei | 3ka7_a | Q8PU56 | 98.30 | 8.30E-11 | 1.20E-14 | 102.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | PF1083 |
PF1083 |
Pyrococcus furiosus | 3nrn_a | Q8U1X1 | 98.20 | 2.60E-10 | 3.50E-14 | 101.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | OXLA |
L-amino acid oxidase (L-AAO) (LAO) (roLAAO) (EC 1.4.3.2) |
1.4.3.2 | Rhodococcus opacus | 2jae_a | Q8VPD4 | 98.50 | 2.30E-11 | 3.20E-15 | 111.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | 6-hlno |
6-hlno |
1.5.3.5 | Paenarthrobacter nicotinovorans | 3k7t_b | Q93NH4 | 98.70 | 3.10E-12 | 4.30E-16 | 113.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | DR_A0367 |
DR_A0367 |
Deinococcus radiodurans | 3hdq_d | Q9RYF1 | 98.50 | 1.60E-11 | 2.10E-15 | 111.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | vioA CV_3274 |
Flavin-dependent L-tryptophan oxidase VioA (EC 1.4.3.23) |
1.4.3.23 | Chromobacterium violaceum | 5g3t_d | Q9S3V1 | 98.10 | 8.40E-10 | 1.20E-13 | 95.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | chaA |
chaA |
Microbacterium oxydans | 4i58_c | R4GRV2 | 98.70 | 1.10E-12 | 1.60E-16 | 117.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | iaaM |
Tryptophan 2-monooxygenase (EC 1.13.12.3) |
1.13.12.3 | Pseudomonas savastanoi | 4iv9_b | P06617 | 97.30 | 1.40E-07 | 1.80E-11 | 89.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | L-lysine oxidase (EC 1.4.3.14) |
L-lysine oxidase (EC 1.4.3.14) |
Hypocrea rufa | 3x0v_a | A0A0J9X1X3 | 97.20 | 2.50E-07 | 3.30E-11 | 85.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | FDP41_009224 NF0049320 |
FDP41_009224 NF0049320 |
Naegleria fowleri | 6c87_a | A0A2R2JFX6 | 99.40 | 2.50E-17 | 3.30E-21 | 151.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | glf MSMEG_6404 |
glf MSMEG_6404 |
Mycolicibacterium smegmatis | 5er9_b | A0R629 | 98.50 | 2.80E-11 | 3.80E-15 | 107.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | PDS1 PDS OsI_010044 |
15-cis-phytoene desaturase, chloroplastic/chromoplastic (EC 1.3.5.5) (Phytoene dehydrogenase) (Phytoene desaturase) |
1.3.5.5 | Oryza sativa | 5mog_b | A2XDA1 | 98.20 | 2.10E-10 | 2.80E-14 | 104.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | puo |
puo |
Rhodococcus erythropolis | 2yg5_a | B0F9F6 | 98.20 | 4.20E-10 | 6.00E-14 | 99.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | Exig_0701 |
Exig_0701 |
1.3.3.15 | Exiguobacterium sibiricum | 3lov_a | B1YKJ9 | 99.30 | 1.20E-16 | 1.80E-20 | 143.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | PPS_4081 |
PPS_4081 |
Pseudomonas putida | 5ttj_a | F8G0P2 | 97.80 | 7.90E-09 | 1.00E-12 | 95.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | PPXII PPOX2 |
Protoporphyrinogen oxidase, mitochondrial (EC 1.3.3.4) (PX-2) (Protoporphyrinogen IX oxidase isozyme II) (PPO II) (PPX II) |
1.3.3.4 | Nicotiana tabacum | 1sez_a | O24164 | 99.40 | 1.30E-17 | 1.70E-21 | 154.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | KDM1A AOF2 KDM1 KIAA0601 LSD1 |
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) |
1.14.99.66 | Homo sapiens | Neuroblastoma,Leukemia, Acute Myeloid,Primary Hyperoxaluria,Loeys-Dietz Syndrome 1,Colorectal Cancer,Rhabdomyosarcoma,Prostate Cancer,Disease Of Mental Health,Loeys-Dietz Syndrome,Ewing Sarcoma,Kabuki Syndrome 1,Kbg Syndrome,Cleft Palate, Psychomotor Retardation, And Distinctive Facial Features,Medulloblastoma |
2z5u_a | O60341 | ENSG00000004487 | KDM1A | 97.50 | 4.90E-08 | 6.10E-12 | 95.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER014W | HEM14 | SGDID:S000000816 | nctB shn_30305 |
nctB shn_30305 |
Shinella | 6cr0_a | A0A075BSX9 | 98.30 | 1.80E-10 | 2.60E-14 | 100.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | OXLA |
L-amino-acid oxidase (BatroxLAAO) (LAO) (EC 1.4.3.2) |
1.4.3.2 | Bothrops atrox | 5ts5_a | P0CC17 | 98.10 | 6.20E-10 | 8.60E-14 | 100.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | MAOA |
Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) |
1.4.3.4 | Homo sapiens | Flying Phobia,Narcolepsy,Migraine With Or Without Aura 1,Bestiality,Phobia, Specific,Alcohol Dependence,Postpartum Depression,Post-Traumatic Stress Disorder,Dysthymic Disorder,Major Depressive Disorder,Paranoid Schizophrenia,Atypical Depressive Disorder,Pathological Gambling,Kleptomania,Intermittent Explosive Disorder,Pyromania,Substance Dependence,Heroin Dependence,Distal Muscular Dystrophy With Anterior Tibial Onset,Psychotic Disorder,Neurotic Disorder,Obsessive-Compulsive Disorder,Sudden Infant Death Syndrome,Conduct Disorder,Narcissistic Personality Disorder,Tic Disorder,Barbiturate Abuse,Chronic Fatigue Syndrome,Melancholia,Exhibitionism,Pedophilia,Serotonin Syndrome,Hepatic Encephalopathy,Trichotillomania,Substance Abuse,Parkinson Disease, Late-Onset,Separation Anxiety Disorder,Sexual Sadism,Voyeurism,Depression,Phobic Disorder,Agoraphobia,Panic Disorder,Pheochromocytoma,Alcoholic Neuropathy,Borderline Personality Disorder,Pick Disease Of Brain,Dependent Personality Disorder,Multiple Personality Disorder,Impulse Control Disorder,Antisocial Personality Disorder,Generalized Anxiety Disorder,Bipolar Disorder,Mood Disorder,Social Phobia,Disease Of Mental Health,Avoidant Personality Disorder,Personality Disorder,Body Mass Index Quantitative Trait Locus 11,Lesch-Nyhan Syndrome,Endogenous Depression,Mental Depression,Brunner Syndrome,Fragile X Syndrome,Schizophrenia,Corneal Dystrophy, Lisch Epithelial,Restless Legs Syndrome,Gilles De La Tourette Syndrome,Tobacco Addiction,Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1,Anorexia Nervosa,Oppositional Defiant Disorder,Huntington Disease,Attention Deficit-Hyperactivity Disorder,Specific Developmental Disorder,Autism Spectrum Disorder,Paraphilia Disorder,Body Dysmorphic Disorder,Bulimia Nervosa,Anxiety,Norrie Disease,Autism,Frontotemporal Dementia |
2z5y_a | P21397 | ENSG00000189221 | MAOA | 98.40 | 3.50E-11 | 4.70E-15 | 110.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER014W | HEM14 | SGDID:S000000816 | GDI1 RABGDIA |
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (SMG p25A GDI) |
Bos taurus | 1d5t_a | P21856 | 97.50 | 3.60E-08 | 5.00E-12 | 87.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | MAOB |
Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) |
1.4.3.4 | Homo sapiens | Supranuclear Palsy, Progressive, 1,Migraine With Or Without Aura 1,Alcohol Dependence,Alzheimer Disease,Post-Traumatic Stress Disorder,Major Depressive Disorder,Amyotrophic Lateral Sclerosis 1,Atypical Depressive Disorder,Aromatic L-Amino Acid Decarboxylase Deficiency,Pathological Gambling,Movement Disease,Psychotic Disorder,Cocaine Abuse,Obsessive-Compulsive Disorder,Dementia,Barbiturate Abuse,Dystonia,Serotonin Syndrome,Hepatic Encephalopathy,Interval Angle-Closure Glaucoma,Parkinson Disease, Late-Onset,Pheochromocytoma,Pick Disease Of Brain,Impulse Control Disorder,Antisocial Personality Disorder,Postencephalitic Parkinson Disease,Mood Disorder,Disease Of Mental Health,Personality Disorder,Toxic Encephalopathy,Dementia, Lewy Body,Brunner Syndrome,Schizophrenia,Restless Legs Syndrome,Asperger Syndrome,Huntington Disease,Attention Deficit-Hyperactivity Disorder,Autism Spectrum Disorder,Multiple System Atrophy 1,Anxiety,Norrie Disease,Autism,Phenylketonuria |
1s3e_b | P27338 | ENSG00000069535 | MAOB | 98.80 | 1.00E-12 | 1.40E-16 | 120.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER014W | HEM14 | SGDID:S000000816 | cgoX hemG hemY BSU10140 |
Coproporphyrinogen III oxidase (EC 1.3.3.15) |
1.3.3.15 | Bacillus subtilis | 3i6d_b | P32397 | 99.50 | 5.00E-19 | 7.10E-23 | 159.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YER014W | HEM14 | SGDID:S000000816 | glf yefE b2036 JW2021 |
UDP-galactopyranose mutase (UGM) (EC 5.4.99.9) (UDP-GALP mutase) (Uridine 5-diphosphate galactopyranose mutase) |
5.4.99.9 | Escherichia coli | 1i8t_a | P37747 | 98.20 | 3.10E-10 | 4.20E-14 | 100.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YER014W | HEM14 | SGDID:S000000816 | GDI1 SEC19 YER136W |
Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor) |
Saccharomyces cerevisiae | 2bcg_g | P39958 | 97.80 | 6.10E-09 | 8.20E-13 | 94.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YER014W | HEM14 | SGDID:S000000816 | maoN |
Monoamine oxidase N (MAO-N) (EC 1.4.3.4) |
1.4.3.4 | Aspergillus niger | 2vvm_a | P46882 | 98.40 | 3.60E-11 | 4.60E-15 | 112.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |