| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YER051W | JHD1 | SGDID:S000000853 | HIF1AN FIH1 |
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase) |
1.14.11.30,1.14.11.n4, | Homo sapiens | Familial Isolated Hypoparathyroidism,Acute Mountain Sickness,Hypoxia,Parathyroid Gland Disease,Renal Cell Carcinoma, Nonpapillary,Erythrocytosis, Familial, 2 |
1h2k_a | Q9NWT6 | 99.70 | 3.00E-21 | 2.30E-25 | 191.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YER051W | JHD1 | SGDID:S000000853 | TYW5 C2orf60 |
tRNA wybutosine-synthesizing protein 5 (hTYW5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) |
1.14.11.42 | Homo sapiens | Mixed Sleep Apnea,Familial Isolated Hypoparathyroidism |
3al5_b | A2RUC4 | ENSG00000162971 | TYW5 | 99.60 | 5.90E-20 | 4.50E-24 | 182.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | UTY KDM6C |
Histone demethylase UTY (EC 1.14.11.68) (Ubiquitously-transcribed TPR protein on the Y chromosome) (Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase UTY) |
1.14.11.68 | Homo sapiens | 4uf0_a | O14607 | ENSG00000183878 | UTY | 99.70 | 2.10E-21 | 1.60E-25 | 201.90 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YER051W | JHD1 | SGDID:S000000853 | KDM6A UTX |
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) |
1.14.11.68 | Homo sapiens | Charge Syndrome,Chronic Myelomonocytic Leukemia,Kleefstra Syndrome,Leukemia, Acute Myeloid,T-Cell Acute Lymphoblastic Leukemia,Microphthalmia,Adhesions Of Uterus,Weaver Syndrome,Sotos Syndrome 1,Turner Syndrome,Disease Of Mental Health,Chromosome 16p13.3 Deletion Syndrome, Proximal,Bartholin'S Gland Carcinoma,Kabuki Syndrome 2,Form Agnosia,Kabuki Syndrome 1,Kbg Syndrome,Methylmalonic Acidemia And Homocysteinemia, Cblx Type,Scoliosis,Autosomal Dominant Non-Syndromic Intellectual Disability,Medulloblastoma |
6ful_a | O15550 | ENSG00000147050 | KDM6A | 99.60 | 1.50E-20 | 1.10E-24 | 197.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | PHF2 CENP-35 KIAA0662 |
Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2) |
1.14.11.- | Homo sapiens | Dissociative Disorder,Culler-Jones Syndrome |
3pua_a | O75151 | ENSG00000197724 | PHF2 | 100.00 | 2.00E-36 | 1.50E-40 | 309.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | JMJD7 |
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase JMJD7) |
1.14.11.63 | Homo sapiens | 5nfo_b | P0C870 | ENSG00000243789 | JMJD7 | 99.70 | 4.10E-22 | 3.20E-26 | 197.80 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YER051W | JHD1 | SGDID:S000000853 | Jmjd7 |
Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase Jmjd7) |
1.14.11.63 | Mus musculus | 4qu2_b | P0C872 | 99.70 | 4.90E-21 | 3.80E-25 | 188.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YER051W | JHD1 | SGDID:S000000853 | Kdm2a Fbl11 Fbxl11 Jhdm1a Kiaa1004 |
Lysine-specific demethylase 2A (EC 1.14.11.27) (F-box and leucine-rich repeat protein 11) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A) |
1.14.11.27 | Mus musculus | 4qx7_a | P59997 | 99.90 | 4.50E-31 | 3.50E-35 | 262.70 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YER051W | JHD1 | SGDID:S000000853 | JMJD1C JHDM2C KIAA1380 TRIP8 |
Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8) |
1.14.11.- | Homo sapiens | Central Nervous System Germinoma,Early Myoclonic Encephalopathy,Digeorge Syndrome,Autism Spectrum Disorder,Rett Syndrome,Autism |
5fzo_a | Q15652 | ENSG00000171988 | JMJD1C | 99.60 | 8.20E-21 | 6.10E-25 | 189.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | Kdm6b Jmjd3 Kiaa0346 |
Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B) |
1.14.11.68 | Mus musculus | 4eyu_a | Q5NCY0 | 99.70 | 3.30E-21 | 2.60E-25 | 200.90 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YER051W | JHD1 | SGDID:S000000853 | JMJD6 KIAA0585 PSR PTDSR |
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) |
1.14.11.- | Homo sapiens | Familial Isolated Hypoparathyroidism,Pancreatitis,Myasthenic Syndrome, Congenital, 15,Myasthenic Syndrome, Congenital, 9, Associated With Acetylcholine Receptor Deficiency |
3k2o_b | Q6NYC1 | ENSG00000070495 | JMJD6 | 99.70 | 1.00E-22 | 8.10E-27 | 202.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | KDM3B C5orf7 JHDM2B JMJD1B KIAA1082 |
Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) |
1.14.11.65 | Homo sapiens | Diets-Jongmans Syndrome,Otopalatodigital Syndrome, Type I |
4c8d_a | Q7LBC6 | ENSG00000120733 | KDM3B | 99.60 | 9.20E-21 | 6.80E-25 | 188.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | KDM8 JMJD5 |
Bifunctional peptidase and arginyl-hydroxylase JMJD5 (EC 1.14.11.73) (EC 3.4.-.-) (JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine (3R)-hydroxylase KDM8) |
1.14.11.73,3.4.-.-, | Homo sapiens | Familial Isolated Hypoparathyroidism,Glycogen Storage Disease Xv |
3uyj_a | Q8N371 | ENSG00000155666 | KDM8 | 99.70 | 5.80E-22 | 4.70E-26 | 187.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | jmjd-1.2 F29B9.2 |
Lysine-specific demethylase 7 homolog (ceKDM7A) (EC 1.14.11.-) (JmjC domain-containing protein 1.2) (PHD finger protein 8 homolog) (PHF8 homolog) |
1.14.11.- | Caenorhabditis elegans | 3n9m_a | Q9GYI0 | 100.00 | 3.30E-45 | 2.50E-49 | 387.40 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | |||
| YER051W | JHD1 | SGDID:S000000853 | HIF1AN FIH1 |
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase) |
1.14.11.30,1.14.11.n4, | Homo sapiens | Familial Isolated Hypoparathyroidism,Acute Mountain Sickness,Hypoxia,Parathyroid Gland Disease,Renal Cell Carcinoma, Nonpapillary,Erythrocytosis, Familial, 2 |
4b7e_a | Q9NWT6 | ENSG00000166135 | HIF1AN | 99.60 | 9.40E-20 | 7.20E-24 | 181.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YER051W | JHD1 | SGDID:S000000853 | PHF8 KIAA1111 ZNF422 |
Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8) |
1.14.11.27,1.14.11.65, | Homo sapiens | Cleft Lip,Cleft Lip/Palate,X-Linked Intellectual Disability, Siderius Type,Sotos Syndrome 1,Alacrima, Achalasia, And Mental Retardation Syndrome,Van Der Woude Syndrome 1,Disease Of Mental Health,Orofacial Cleft,Non-Syndromic X-Linked Intellectual Disability,Borjeson-Forssman-Lehmann Syndrome,Acute Promyelocytic Leukemia,Kabuki Syndrome 1,Syndromic X-Linked Intellectual Disability,Autism,Syndromic X-Linked Intellectual Disability Siderius Type |
2wwu_a | Q9UPP1 | ENSG00000172943 | PHF8 | 100.00 | 8.10E-36 | 6.30E-40 | 302.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |