| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YGL004C | RPN14 | SGDID:S000002972 | WDR5 BIG3 |
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) |
Homo sapiens | Kleefstra Syndrome,Kabuki Syndrome 1 |
2h9l_a | P61964 | ENSG00000196363 | WDR5 | 99.10 | 1.10E-14 | 7.20E-19 | 128.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGL004C | RPN14 | SGDID:S000002972 | PRPF19 NMP200 PRP19 SNEV |
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) |
2.3.2.27 | Homo sapiens | Retinitis Pigmentosa 19,Poikiloderma With Neutropenia |
4lg8_a | Q9UMS4 | ENSG00000110107 | PRPF19 | 99.10 | 1.20E-14 | 8.10E-19 | 129.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL004C | RPN14 | SGDID:S000002972 | WDR33 WDC146 |
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa) |
Homo sapiens | Atrial Septal Defect 6 |
6f9n_b | Q9C0J8 | ENSG00000136709 | WDR33 | 99.00 | 1.30E-13 | 8.20E-18 | 124.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGL004C | RPN14 | SGDID:S000002972 | MLST8 GBL LST8 |
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8) |
Homo sapiens | Cowden Syndrome,Cowden Syndrome 1,Subependymal Glioma,Benign Ependymoma,Kidney Angiomyolipoma,Tuberous Sclerosis 2,Proteus Syndrome,Tuberous Sclerosis 1 |
4jsx_c | Q9BVC4 | ENSG00000167965 | MLST8 | 98.90 | 1.60E-13 | 1.10E-17 | 119.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGL004C | RPN14 | SGDID:S000002972 | Guanine nucleotide-binding protein subunit beta-like protein |
Guanine nucleotide-binding protein subunit beta-like protein |
Leishmania donovani | 5t2a_7 | Q9BIJ5 | 98.90 | 2.60E-13 | 1.70E-17 | 117.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | SPBPJ4664.04 |
Putative coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) |
Schizosaccharomyces pombe | 4j87_a | Q96WV5 | 99.20 | 3.00E-15 | 2.00E-19 | 130.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | TaGB1 |
TaGB1 |
Triticum aestivum | 4v7e_bg | Q8LNY6 | 99.00 | 4.20E-14 | 2.70E-18 | 126.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | KLLA0_E24487g |
KLLA0_E24487g |
Kluyveromyces lactis | 6chg_a | Q6CLY5 | 99.00 | 7.70E-14 | 5.00E-18 | 121.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | Tc00.1047053511211.120 Tc00.1047053511211.130 |
Tc00.1047053511211.120 Tc00.1047053511211.130 |
Trypanosoma cruzi | 5opt_p | Q4DTN2 | 98.90 | 2.70E-13 | 1.80E-17 | 117.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | DAW1 ODA16 |
Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16) |
Chlamydomonas reinhardtii | 5mzh_a | Q3Y8L7 | 99.00 | 1.10E-13 | 6.90E-18 | 128.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | SMD1 YGR074W |
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1) |
Saccharomyces cerevisiae | 5nrl_h | Q02260 | 98.90 | 2.30E-13 | 1.50E-17 | 126.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | Gnb5 |
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5) |
Mus musculus | 2pbi_d | P62881 | 98.90 | 1.60E-13 | 1.10E-17 | 121.80 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | GNB1 |
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) |
Bos taurus | 1tbg_c | P62871 | 98.90 | 2.50E-13 | 1.60E-17 | 119.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | SNRPE |
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE) |
Homo sapiens | Hypotrichosis,Spinal Muscular Atrophy,Hypotrichosis 11,Hypotrichosis Simplex,Hypotrichosis 8,Hypotrichosis 7,Hypotrichosis 4,Systemic Lupus Erythematosus,Hypotrichosis 6,Microcephalic Osteodysplastic Primordial Dwarfism, Type I |
6id1_e | P62304 | ENSG00000182004 | SNRPE | 98.90 | 2.90E-13 | 1.90E-17 | 120.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGL004C | RPN14 | SGDID:S000002972 | TUP1 AAR1 AER2 AMM1 CYC9 FLK1 SFL2 UMR7 YCR084C YCR84C |
General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2) |
Saccharomyces cerevisiae | 1erj_a | P16649 | 99.10 | 7.20E-15 | 4.70E-19 | 133.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | CDH1 HCT1 YGL003C |
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1) |
Saccharomyces cerevisiae | 4bh6_f | P53197 | 99.00 | 8.50E-14 | 5.50E-18 | 120.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | RPN14 YGL004C |
26S proteasome regulatory subunit RPN14 (Proteasome non-ATPase subunit 14) |
Saccharomyces cerevisiae | 3acp_a | P53196 | 99.80 | 9.80E-24 | 6.30E-28 | 194.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | pkwA pkw1 |
Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1) |
2.7.11.1 | Thermomonospora curvata | 5yzv_b | P49695 | 98.90 | 2.50E-13 | 1.60E-17 | 117.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL004C | RPN14 | SGDID:S000002972 | PFS2 YNL317W N0348 |
Polyadenylation factor subunit 2 |
Saccharomyces cerevisiae | 6eoj_d | P42841 | 99.00 | 3.60E-14 | 2.40E-18 | 132.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | SEC27 YGL137W G2827 |
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) |
Saccharomyces cerevisiae | 2yno_b | P41811 | 98.90 | 2.10E-13 | 1.40E-17 | 119.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | LST8 YNL006W N2005 |
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (Lethal with SEC13 protein 8) |
Saccharomyces cerevisiae | 6emk_d | P41318 | 99.10 | 1.20E-14 | 8.10E-19 | 125.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | SMX2 SNP2 YFL017W-A YFL017Bw |
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG) |
Saccharomyces cerevisiae | 5zwm_k | P40204 | 98.90 | 2.30E-13 | 1.50E-17 | 126.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | RSA4 YCR072C YCR72C |
Ribosome assembly protein 4 (Notchless protein homolog 1) (Ribosome biogenesis factor RSA4) |
Saccharomyces cerevisiae | 4wju_a | P25382 | 99.00 | 1.20E-13 | 7.90E-18 | 129.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | TUP1 AAR1 AER2 AMM1 CYC9 FLK1 SFL2 UMR7 YCR084C YCR84C |
General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2) |
Saccharomyces cerevisiae | 1erj_b | P16649 | 99.00 | 1.40E-13 | 9.30E-18 | 124.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | PLRG1 |
Pleiotropic regulator 1 |
Homo sapiens | Poikiloderma With Neutropenia,Cardiac Valvular Dysplasia, X-Linked |
4yvd_a | O43660 | ENSG00000171566 | PLRG1 | 98.90 | 1.60E-13 | 1.10E-17 | 122.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGL004C | RPN14 | SGDID:S000002972 | CTHT_0048280 |
CTHT_0048280 |
Chaetomium thermophilum | 5oql_f | G0SAY9 | 99.00 | 5.10E-14 | 3.30E-18 | 134.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | Dtox_1751 |
Dtox_1751 |
Desulfofarcimen acetoxidans | 3u4y_a | C8VX32 | 98.90 | 2.80E-13 | 1.80E-17 | 119.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL004C | RPN14 | SGDID:S000002972 | Dynein tail |
Dynein tail |
Sus scrofa | 5afu_3 | A0A0J9X2A1 | 99.00 | 1.10E-13 | 7.00E-18 | 123.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |