| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YGR070W | ROM1 | SGDID:S000003302 | ARHGEF4 KIAA1112 |
Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor 1) (Asef) (Asef1) |
Homo sapiens | Locked-In Syndrome,Epidermolysis Bullosa Simplex, Dowling-Meara Type |
2pz1_a | Q9NR80 | ENSG00000136002 | ARHGEF4 | 99.90 | 4.30E-27 | 3.80E-31 | 277.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR070W | ROM1 | SGDID:S000003302 | CNH |
CNH domain |
pfam Family | PF00780 | 99.80 | 2.80E-26 | 2.40E-30 | 254.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| YGR070W | ROM1 | SGDID:S000003302 | Arhgef3 |
Rho guanine nucleotide exchange factor 3 |
Mus musculus | 2z0q_a | Q91X46 | 99.80 | 1.40E-26 | 1.30E-30 | 262.10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR070W | ROM1 | SGDID:S000003302 | FGD5 ZFYVE23 |
FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23) |
Homo sapiens | Gastroduodenitis,Aarskog-Scott Syndrome |
3mpx_a | Q6ZNL6 | ENSG00000154783 | FGD5 | 99.90 | 7.60E-29 | 6.70E-33 | 289.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR070W | ROM1 | SGDID:S000003302 | AKAP13 BRX HT31 LBC |
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) |
Homo sapiens | Corneal Dystrophy,Long Qt Syndrome,Breast Cancer,Crouzon Syndrome With Acanthosis Nigricans,Long Qt Syndrome 1 |
4d0n_b | Q12802 | ENSG00000170776 | AKAP13 | 99.90 | 1.10E-26 | 9.70E-31 | 265.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR070W | ROM1 | SGDID:S000003302 | ARHGEF11 KIAA0380 |
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF) |
Homo sapiens | Fetal Macrosomia |
1xcg_e | O15085 | ENSG00000132694 | ARHGEF11 | 99.80 | 1.20E-26 | 1.10E-30 | 264.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR070W | ROM1 | SGDID:S000003302 | ARHGEF1 |
Rho guanine nucleotide exchange factor 1 (115 kDa guanine nucleotide exchange factor) (p115-RhoGEF) (p115RhoGEF) (Sub1.5) |
Homo sapiens | Atrophic Rhinitis,Giant Axonal Neuropathy,Megaesophagus,Skin Lipoma,Immunodeficiency 62 |
3odo_a | Q92888 | ENSG00000076928 | ARHGEF1 | 99.80 | 2.30E-26 | 2.00E-30 | 263.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR070W | ROM1 | SGDID:S000003302 | NET1 ARHGEF8 |
Neuroepithelial cell-transforming gene 1 protein (Proto-oncogene p65 Net1) (Rho guanine nucleotide exchange factor 8) |
Homo sapiens | Breast Cancer,Skin Squamous Cell Carcinoma,Oppositional Defiant Disorder |
4xh9_d | Q7Z628 | ENSG00000173848 | NET1 | 99.90 | 4.10E-29 | 3.50E-33 | 285.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR070W | ROM1 | SGDID:S000003302 | AFUA_5G08550 |
AFUA_5G08550 |
Neosartorya fumigata | 5o51_a | Q4WUI2 | 99.90 | 2.20E-32 | 1.80E-36 | 312.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR070W | ROM1 | SGDID:S000003302 | Vav1 Vav |
Proto-oncogene vav (p95vav) |
Mus musculus | 2vrw_b | P27870 | 99.80 | 2.70E-26 | 2.40E-30 | 265.10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |