| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YGR083C | GCD2 | SGDID:S000003315 | GCD7 TIF222 YLR291C L8003.17 |
Translation initiation factor eIF-2B subunit beta (GCD complex subunit GCD7) (Guanine nucleotide exchange factor subunit GCD7) (eIF-2B GDP-GTP exchange factor subunit beta) |
Saccharomyces cerevisiae | 6i3m_f | P32502 | 100.00 | 8.80E-45 | 7.60E-49 | 390.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | mtnA TM_0911 |
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) |
5.3.1.23 | Thermotoga maritima | 1t9k_d | Q9X013 | 100.00 | 6.90E-47 | 5.90E-51 | 401.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | tif222 SPAC343.14c |
Probable translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta) |
Schizosaccharomyces pombe | 5b04_c | Q9UT76 | 100.00 | 1.50E-48 | 1.30E-52 | 421.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | tif221 SPCC11E10.07c |
Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) |
Schizosaccharomyces pombe | 5b04_a | Q9USP0 | 100.00 | 2.30E-45 | 2.00E-49 | 389.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | EIF2B4 EIF2BD |
Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) |
Homo sapiens | Childhood Ataxia With Central Nervous System Hypomyelination / Vanishing White Matter,Leukoencephalopathy, Hereditary Diffuse, With Spheroids,Leukodystrophy,Premature Menopause,Glycogen Storage Disease Xv,Cerebral Degeneration,Mehmo Syndrome,Leukoencephalopathy With Vanishing White Matter,Combined Saposin Deficiency,Biotinidase Deficiency |
6caj_e | Q9UI10 | 100.00 | 2.50E-61 | 2.00E-65 | 534.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | MRI1 MRDI UNQ6390/PRO21135 |
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) |
5.3.1.23 | Homo sapiens | Epilepsy,Infantile Epilepsy Syndrome,Epilepsy, Familial Temporal Lobe, 3 |
4ldr_b | Q9BV20 | ENSG00000037757 | MRI1 | 100.00 | 8.20E-47 | 7.10E-51 | 404.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGR083C | GCD2 | SGDID:S000003315 | LmjF36.4930 LmjF_36_4930 |
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) |
5.3.1.23 | Leishmania major | 2a0u_a | Q4Q0R9 | 100.00 | 1.40E-47 | 1.20E-51 | 412.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | EIF2B1 EIF2BA |
Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) |
Homo sapiens | Type 1 Diabetes Mellitus 22,Childhood Ataxia With Central Nervous System Hypomyelination / Vanishing White Matter,Leukodystrophy,Cerebral Degeneration,Leukoencephalopathy With Vanishing White Matter,Megalencephalic Leukoencephalopathy With Subcortical Cysts 1,Spastic Ataxia 4 |
3ecs_c | Q14232 | 100.00 | 1.20E-47 | 1.00E-51 | 402.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | tif224 SPAC21E11.06 |
Probable translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) |
Schizosaccharomyces pombe | 5b04_h | Q09924 | 100.00 | 1.80E-65 | 1.40E-69 | 563.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | EIF2B2 EIF2BB |
Translation initiation factor eIF-2B subunit beta (S20I15) (S20III15) (eIF-2B GDP-GTP exchange factor subunit beta) |
Homo sapiens | Childhood Ataxia With Central Nervous System Hypomyelination / Vanishing White Matter,Leukodystrophy,Premature Menopause,Cerebral Degeneration,Mehmo Syndrome,Leukoencephalopathy With Vanishing White Matter,Lynch Syndrome,Combined Saposin Deficiency,Multiple Synostoses Syndrome,Perrault Syndrome,Spastic Ataxia 4 |
6caj_c | P49770 | ENSG00000119718 | EIF2B2 | 100.00 | 1.30E-48 | 1.10E-52 | 418.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGR083C | GCD2 | SGDID:S000003315 | AF_0370 |
Putative methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (MTNA-like protein) (aMTNA) (S-methyl-5-thioribose-1-phosphate isomerase) |
5.3.1.23 | Archaeoglobus fulgidus | 1t5o_a | O29877 | 100.00 | 7.20E-55 | 5.90E-59 | 461.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | GCN3 AAS2 TIF221 YKR026C |
Translation initiation factor eIF-2B subunit alpha (GCD complex subunit GCN3) (Guanine nucleotide exchange factor subunit GCN3) (Translational activator GCN3) (eIF-2B GDP-GTP exchange factor subunit alpha) |
Saccharomyces cerevisiae | 6i3m_a | P14741 | 100.00 | 1.10E-45 | 9.40E-50 | 385.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | GCD2 TIF224 YGR083C |
Translation initiation factor eIF-2B subunit delta (GCD complex subunit GCD2) (Guanine nucleotide exchange factor subunit GCD2) (eIF-2B GDP-GTP exchange factor subunit delta) |
Saccharomyces cerevisiae | 6i3m_c | P12754 | 100.00 | 6.00E-133 | 5.00E-137 | 1126.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | PH0702 |
Putative methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (MTNA-like protein) (aMTNA) (S-methyl-5-thioribose-1-phosphate isomerase) |
5.3.1.23 | Pyrococcus horikoshii | 6a34_b | O58433 | 100.00 | 1.30E-45 | 1.10E-49 | 394.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | PH0440 |
Putative translation initiation factor eIF-2B subunit 2-like (eIF-2B GDP-GTP exchange factor) |
Pyrococcus horikoshii | 1vb5_b | O58185 | 100.00 | 1.10E-40 | 9.40E-45 | 342.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | PH0208 |
Ribose 1,5-bisphosphate isomerase (R15P isomerase) (R15Pi) (EC 5.3.1.29) (Ribulose 1,5-bisphosphate synthase) (RuBP synthase) |
5.3.1.29 | Pyrococcus horikoshii | 5yfj_a | O57947 | 100.00 | 3.80E-49 | 3.30E-53 | 415.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | mtnA ykrS BSU13550 |
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) |
5.3.1.23 | Bacillus subtilis | 2yvk_d | O31662 | 100.00 | 1.80E-50 | 1.50E-54 | 433.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | AF_0370 |
Putative methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (MTNA-like protein) (aMTNA) (S-methyl-5-thioribose-1-phosphate isomerase) |
5.3.1.23 | Archaeoglobus fulgidus | 1t5o_b | O29877 | 100.00 | 1.10E-47 | 9.10E-52 | 408.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR083C | GCD2 | SGDID:S000003315 | CTHT_0063470 |
CTHT_0063470 |
Chaetomium thermophilum | 4zem_a | G0SEE6 | 100.00 | 2.80E-48 | 2.40E-52 | 419.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR083C | GCD2 | SGDID:S000003315 | CTHT_0028980 |
CTHT_0028980 |
Chaetomium thermophilum | 4zeo_a | G0S811 | 100.00 | 1.20E-62 | 9.30E-67 | 540.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |