| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YHR067W | HTD2 | SGDID:S000001109 | phaJ |
(R)-specific enoyl-CoA hydratase (EC 4.2.1.119) |
4.2.1.119 | Aeromonas caviae | 1iq6_a | O32472 | 99.50 | 1.20E-18 | 9.50E-23 | 135.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | MSMEG_1341 |
MSMEG_1341 |
Mycolicibacterium smegmatis | 4rv2_b | A0QS41 | 98.60 | 7.60E-12 | 6.00E-16 | 96.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YHR067W | HTD2 | SGDID:S000001109 | MSMEG_6754 |
MSMEG_6754 |
Mycolicibacterium smegmatis | 4v12_a | A0R724 | 99.50 | 5.10E-19 | 4.00E-23 | 157.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YHR067W | HTD2 | SGDID:S000001109 | mch Caur_0173 |
Beta-methylmalyl-CoA dehydratase (EC 4.2.1.148) (2-methylfumaryl-CoA hydratase) (Mesaconyl-CoA hydratase) |
4.2.1.148 | Chloroflexus aurantiacus | 4e3e_b | A9WC34 | 99.30 | 2.30E-16 | 1.80E-20 | 140.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | MaoC |
MaoC |
Phytophthora capsici | 3kh8_a | E3T2G3 | 99.70 | 3.00E-21 | 2.30E-25 | 172.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YHR067W | HTD2 | SGDID:S000001109 | htdY Rv3389c |
3-hydroxyacyl-thioester dehydratase Y (EC 4.2.1.-) |
4.2.1.- | Mycobacterium tuberculosis | 3khp_a | I6YBZ8 | 99.70 | 8.30E-22 | 6.60E-26 | 174.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | AF_1124 |
AF_1124 |
Archaeoglobus fulgidus | 3k67_b | O29141 | 98.60 | 6.90E-12 | 5.50E-16 | 98.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YHR067W | HTD2 | SGDID:S000001109 | htdX Rv0241c |
3-hydroxyacyl-thioester dehydratase X (EC 4.2.1.-) (3-hydroxybutyryl-CoA dehydratase) (EC 4.2.1.55) |
4.2.1.55 | Mycobacterium tuberculosis | 4oob_a | O53664 | 99.70 | 5.60E-22 | 4.40E-26 | 171.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | FAS1 YKL182W |
Fatty acid synthase subunit beta (EC 2.3.1.86) [Includes: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9); [Acyl-carrier-protein] acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] malonyltransferase (EC 2.3.1.39); S-acyl fatty acid synthase thioesterase (EC 3.1.2.14)] |
1.3.1.9,2.3.1.38,2.3.1.39,2.3.1.86,3.1.2.14,4.2.1.59, | Saccharomyces cerevisiae | 2uv8_i | P07149 | 99.30 | 1.50E-16 | 1.10E-20 | 168.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | FOX2 |
Peroxisomal hydratase-dehydrogenase-epimerase (HDE) (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.119); (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12)] |
1.1.1.n12,4.2.1.119, | Candida tropicalis | 1pn2_a | P22414 | 99.70 | 1.80E-22 | 1.40E-26 | 175.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | HSD17B4 EDH17B4 SDR8C1 |
Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] |
1.1.1.n12,4.2.1.107,4.2.1.119 | Homo sapiens | Refsum Disease, Classic,Zellweger Syndrome,Peroxisomal Disease,Rhizomelic Chondrodysplasia Punctata, Type 1,Peroxisomal Biogenesis Disorder,Rare Genetic Deafness,Peroxisome Biogenesis Disorder 1b,Rhizomelic Chondrodysplasia Punctata,Polyhydramnios,Leukodystrophy,Premature Menopause,46 Xx Gonadal Dysgenesis,Adrenoleukodystrophy,Perrault Syndrome 1,Alpha-Methylacyl-Coa Racemase Deficiency,Multiple Synostoses Syndrome,Perrault Syndrome,D-Bifunctional Protein Deficiency,Peroxisomal Acyl-Coa Oxidase Deficiency |
1s9c_a | P51659 | ENSG00000133835 | HSD17B4 | 99.70 | 3.90E-21 | 3.10E-25 | 168.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YHR067W | HTD2 | SGDID:S000001109 | MT0226 |
MT0226 |
Mycobacterium tuberculosis | 2bi0_a | P96398 | 99.20 | 3.40E-15 | 2.70E-19 | 132.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YHR067W | HTD2 | SGDID:S000001109 | htdZ Rv0130 |
3-hydroxyacyl-thioester dehydratase Z (EC 4.2.1.-) (3-hydroxybutyryl-CoA dehydratase) (EC 4.2.1.55) (N-related protein) (Nodulation protein) |
4.2.1.55 | Mycobacterium tuberculosis | 2c2i_b | P9WNP3 | 98.60 | 7.30E-12 | 5.90E-16 | 97.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR067W | HTD2 | SGDID:S000001109 | Mfe2 CG3415 |
Peroxisomal multifunctional enzyme type 2 (DmMFE-2) [Includes: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.119)] |
1.1.1.n12,4.2.1.119, | Drosophila melanogaster | 3oml_a | Q9VXJ0 | 99.70 | 8.10E-22 | 6.50E-26 | 189.10 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |