YHR218W YHR218W / SGDID:S000001261
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YHR218W YHR218W SGDID:S000001261
dbp5 SPBC12C2.06
ATP-dependent RNA helicase dbp5 (EC 3.6.4.13)
 3.6.4.13 Schizosaccharomyces pombe
3fho_b Q09747 98.20 5.90E-10 6.00E-14 116.60 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
EIF4A3 DDX48 KIAA0111
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
 3.6.4.13 Homo sapiens
Metaphyseal Chondrodysplasia, Schmid Type,Robin Sequence With Cleft Mandible And Limb Anomalies,Dysostosis,Vaginal Cancer,Neurodegeneration With Brain Iron Accumulation,Thrombocytopenia-Absent Radius Syndrome,Mandibulofacial Dysostosis, Guion-Almeida Type,Acrofacial Dysostosis
 6qdv_7 P38919 ENSG00000141543 EIF4A3 98.50 2.90E-11 3.40E-15 114.50 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
DHH1 YDL160C
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1)
 3.6.4.13 Saccharomyces cerevisiae
1s2m_a P39517 98.20 3.20E-10 3.70E-14 108.40 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
RAD26 GTA1085 YJR035W J1606
DNA repair and recombination protein RAD26 (EC 3.6.4.12) (ATP-dependent helicase RAD26)
 3.6.4.12 Saccharomyces cerevisiae
5vvr_m P40352 98.30 1.90E-10 1.80E-14 132.70 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
RECQL RECQ1 RECQL1
ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)
 3.6.4.12 Homo sapiens
Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Inherited Cancer-Predisposing Syndrome,Ovarian Cancer,Hereditary Breast Ovarian Cancer Syndrome,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Tumor Predisposition Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Bloom Syndrome,Rapadilino Syndrome
 2v1x_b P46063 ENSG00000004700 RECQL 98.30 2.30E-10 2.40E-14 122.10 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
EIF4A1 DDX2A EIF4A
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
 3.6.4.13 Homo sapiens
Ovary Sarcoma
 5zc9_a P60842 ENSG00000161960 EIF4A1 98.50 2.80E-11 3.30E-15 115.10 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
secA2 Rv1821 MTCY1A11.22c
Protein translocase subunit SecA 2
 Mycobacterium tuberculosis
4uaq_a P9WGP3 98.30 1.70E-10 1.70E-14 126.80 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
SSL2 LOM3 RAD25 UVS112 YIL143C
General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (DNA repair helicase RAD25) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2)
 3.6.4.12 Saccharomyces cerevisiae
5fmf_1 Q00578 98.30 1.60E-10 1.70E-14 117.90 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
HAS1 YMR290C
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
 3.6.4.13 Saccharomyces cerevisiae
5z3g_y Q03532 98.30 1.10E-10 1.20E-14 119.00 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
SWR1 YDR334W D9651.6
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1)
 3.6.4.12 Saccharomyces cerevisiae
6gej_m Q05471 98.50 1.70E-11 1.50E-15 146.10 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
SUB2 YDL084W
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2)
 3.6.4.13 Saccharomyces cerevisiae
5sup_b Q07478 98.50 2.50E-11 2.90E-15 115.70 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
SKI2 YLR398C L8084.17
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2)
 3.6.4.13 Saccharomyces cerevisiae
4buj_a P35207 98.20 4.00E-10 4.00E-14 128.40 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
MJ0669
Probable ATP-dependent RNA helicase MJ0669 (EC 3.6.4.13)
 3.6.4.13 Methanocaldococcus jannaschii
1hv8_a Q58083 98.30 2.10E-10 2.50E-14 106.80 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
Autoprotease p20 (EC 2.7.7.48) (EC 3.4.21.113) (EC 3.6.1.15) (EC 3.6.4.13) (Capsid protein C) (Cysteine protease NS2) (E(rns) glycoprotein) (Envelope glycoprotein E1) (Envelope glycoprotein E2) (Genome polyprotein) (N-terminal protease) (NS5B) (Non-structural protein 2) (Non-structural protein 2-3) (Non-structural protein 3) (Non-structural protein 4A) (Non-structural protein 4B) (Non-structural protein 5A) (RNA-directed RNA polymerase) (Serine protease NS3) (Viroporin p7) (gp33) (gp44/48) (gp55)
Autoprotease p20 (EC 2.7.7.48) (EC 3.4.21.113) (EC 3.6.1.15) (EC 3.6.4.13) (Capsid protein C) (Cysteine protease NS2) (E(rns) glycoprotein) (Envelope glycoprotein E1) (Envelope glycoprotein E2) (Genome polyprotein) (N-terminal protease) (NS5B) (Non-structural protein 2) (Non-structural protein 2-3) (Non-structural protein 3) (Non-structural protein 4A) (Non-structural protein 4B) (Non-structural protein 5A) (RNA-directed RNA polymerase) (Serine protease NS3) (Viroporin p7) (gp33) (gp44/48) (gp55)
 2.7.7.48,3.4.21.113,3.6.1.15,3.6.4.13, Classical swine
5wx1_a Q5U8X5 98.20 6.30E-10 6.20E-14 122.10 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
Ddx58
Antiviral innate immune response receptor RIG-I (DEAD box protein 58) (Probable ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
 3.6.4.13 Mus musculus
3tbk_a Q6Q899 98.60 9.80E-12 1.10E-15 126.40 0 0 1 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
DNA repair and recombination protein RAD54-like (EC 3.6.4.12)
 Danio rerio
1z3i_x Q7ZV09 98.40 7.10E-11 7.70E-15 124.10 0 0 0 1 0 0 0 0
YHR218W YHR218W SGDID:S000001261
Ifih1
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Helicase with 2 CARD domains) (Helicard) (Interferon induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (RIG-I-like receptor 2) (RLR-2)
 3.6.4.13 Mus musculus
6g19_a Q8R5F7 98.30 1.50E-10 1.70E-14 123.10 0 0 1 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
PF2015
PF2015
 Pyrococcus furiosus
1wp9_a Q8TZH8 98.40 6.20E-11 7.70E-15 113.30 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
ST2459 STK_24590
ST2459 STK_24590
 3.6.4.13 Sulfurisphaera tokodaii
2z0m_a Q96XQ7 98.20 2.30E-10 2.80E-14 104.50 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
SSO1653
SSO1653
 Saccharolobus solfataricus
1z63_b Q97XQ7 98.30 2.00E-10 2.30E-14 115.60 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
DR_1289
DR_1289
 3.6.4.12 Deinococcus radiodurans
4q47_a Q9RUU2 98.30 1.10E-10 1.20E-14 120.60 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
DDX19B DBP5 DDX19 TDBP
ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B)
 3.6.4.13 Homo sapiens
Anterior Horn Cell Disease,Lethal Congenital Contracture Syndrome 1,Lethal Congenital Contracture Syndrome
 6b4j_e Q9UMR2 ENSG00000157349 DDX19B 98.10 5.70E-10 6.60E-14 108.90 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
recQ b3822 JW5855
ATP-dependent DNA helicase RecQ (EC 3.6.4.12)
 3.6.4.12 Escherichia coli
1oyw_a P15043 98.20 3.00E-10 3.30E-14 116.40 0 0 0 0 0 0 0 1
YHR218W YHR218W SGDID:S000001261
MSMEG_1757
MSMEG_1757
 Mycolicibacterium smegmatis
5v9x_a A0QT91 98.10 6.50E-10 6.50E-14 124.20 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
RIG-I
RIG-I
 3.6.4.13 Anas platyrhynchos
4a36_a D3TI84 98.20 2.50E-10 2.80E-14 116.00 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
MDA5
MDA5
 3.6.4.13 Gallus gallus
5jcf_b D9N195 98.30 1.50E-10 1.60E-14 123.50 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
RNA helicase (EC 3.6.4.13)
RNA helicase (EC 3.6.4.13)
 3.6.4.13 Gallus gallus
5jaj_a G0YYQ5 98.60 6.90E-12 7.50E-16 133.50 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
MYCTH_115909
MYCTH_115909
 Myceliophthora thermophila
5hzr_a G2QDW1 98.20 3.50E-10 3.70E-14 122.50 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
MYCTH_2307364
MYCTH_2307364
 Myceliophthora thermophila
5jxr_a G2QFM3 98.50 2.60E-11 2.50E-15 133.80 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
BmVLG
BmVLG
 3.6.4.13 Bombyx mori
4d25_a O01378 98.30 1.80E-10 2.10E-14 111.80 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
RECQL5 RECQ5
ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)
 3.6.4.12 Homo sapiens
Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Werner Syndrome,Fanconi Anemia, Complementation Group A,Bloom Syndrome,Rapadilino Syndrome
 5lb3_e O94762 ENSG00000108469 RECQL5 98.20 4.10E-10 4.60E-14 110.80 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
TIF1 TIF41A YKR059W; TIF2 TIF41B YJL138C J0660
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
 3.6.4.13 Saccharomyces cerevisiae
1fuu_b P10081 98.40 4.70E-11 5.50E-15 114.20 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
secA azi pea prlD b0098 JW0096
Protein translocase subunit SecA
 Escherichia coli
3bxz_b P10408 98.20 4.20E-10 4.60E-14 113.00 0 0 0 0 0 0 0 1
YHR218W YHR218W SGDID:S000001261
cshA GT50_10605
cshA GT50_10605
 Geobacillus stearothermophilus
5ivl_b A0A0K2H973 98.40 8.30E-11 9.60E-15 114.70 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
MSS116 YDR194C YD9346.05C
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13)
 3.6.4.13 Saccharomyces cerevisiae
3i5x_a P15424 98.20 3.80E-10 4.10E-14 117.00 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
ERCC3 XPB XPBC
General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
 3.6.4.12 Homo sapiens
Cerebro-Oculo-Facio-Skeletal Syndrome,Ichthyosis,Retinitis Pigmentosa,Hair Disease,Robinow Syndrome, Autosomal Recessive 1,Cockayne Syndrome A,Xeroderma Pigmentosum-Cockayne Syndrome Complex,Xeroderma Pigmentosum Group E,Trichothiodystrophy 1, Photosensitive,Cockayne Syndrome,Trichothiodystrophy,Breast Cancer,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Complementation Group D,Xeroderma Pigmentosum, Variant Type,Xeroderma Pigmentosum, Complementation Group F,Xeroderma Pigmentosum, Complementation Group G,Skin Carcinoma,Xeroderma Pigmentosum, Complementation Group B,Xfe Progeroid Syndrome,Autosomal Recessive Disease,Trichothiodystrophy 2, Photosensitive,Trichothiodystrophy 3, Photosensitive,Ifap Syndrome 1, With Or Without Bresheck Syndrome,Uv-Sensitive Syndrome
 5of4_a P19447 ENSG00000163161 ERCC3 98.50 1.60E-11 1.60E-15 130.40 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
DBP5 RAT8 YOR046C
ATP-dependent RNA helicase DBP5 (EC 3.6.4.13) (DEAD box protein 5) (Helicase CA5/6) (Ribonucleic acid-trafficking protein 8)
 3.6.4.13 Saccharomyces cerevisiae
3pey_a P20449 98.30 1.20E-10 1.50E-14 110.60 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
PRP5 RNA5 YBR237W YBR1603
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (EC 3.6.4.13)
 3.6.4.13 Saccharomyces cerevisiae
4ljy_a P21372 98.40 4.70E-11 5.40E-15 119.60 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
SNF2 GAM1 RIC1 SWI2 TYE3 YOR290C
Transcription regulatory protein SNF2 (EC 3.6.4.-) (ATP-dependent helicase SNF2) (Regulatory protein GAM1) (Regulatory protein SWI2) (SWI/SNF complex component SNF2) (Transcription factor TYE3)
 3.6.4.- Saccharomyces cerevisiae
6iy2_o P22082 98.40 6.80E-11 6.80E-15 128.70 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
PRP28 YDR243C YD8419.10C
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8)
 3.6.4.13 Saccharomyces cerevisiae
4w7s_a P23394 98.30 1.30E-10 1.50E-14 114.80 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
DDX6 HLR2 RCK
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
 3.6.4.13 Homo sapiens
Nodal Marginal Zone Lymphoma,Non-Specific Syndromic Intellectual Disability,Noonan Syndrome 3,Telecanthus,Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies
 4ct4_b P26196 ENSG00000110367 DDX6 98.30 1.30E-10 1.50E-14 109.50 1 1 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
POLG
Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
 2.1.1.56,2.1.1.57,2.7.7.48,3.4.21.91,3.6.1.15,3.6.4.13, Japanese encephalitis
2z83_a P27395 98.30 2.30E-10 2.40E-14 115.90 0 0 0 0 0 0 0 0
YHR218W YHR218W SGDID:S000001261
CHD1 YER164W SYGP-ORF4
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)
 3.6.4.- Saccharomyces cerevisiae
6ftx_w P32657 98.20 4.20E-10 4.20E-14 125.70 0 0 0 0 0 0 0 0