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AnalogYeast
One stop shop for finding analogs for your favorite yeast protein

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YIL125W KGD1 / SGDID:S000001387
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YIL125W KGD1 SGDID:S000001387
TKT TKT1 PICST_67105
Transketolase (TK) (EC 2.2.1.1)
2.2.1.1 Scheffersomyces stipitis
5xvt_a P34736 100.00 2.30E-35 1.60E-39 359.10 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
dxs DR_1475
1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)
2.2.1.7 Deinococcus radiodurans
2o1x_b Q9RUB5 100.00 9.40E-40 6.90E-44 394.30 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
LL1502 L138230
Probable phosphoketolase (EC 4.1.2.-)
4.1.2.- Lactococcus lactis
6gua_a Q9CFH4 99.90 1.00E-33 7.50E-38 348.80 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
TKT
TKT
2.2.1.1 Leishmania mexicana
1r9j_a Q8MPM3 100.00 5.90E-39 4.30E-43 390.00 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
TKTC
Transketolase, chloroplastic (TK) (EC 2.2.1.1)
2.2.1.1 Zea mays
1itz_b Q7SIC9 100.00 2.10E-37 1.50E-41 375.80 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
TTHA0108
TTHA0108
2.2.1.1 Thermus thermophilus
2e6k_a Q5SM35 100.00 3.60E-38 2.60E-42 381.90 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
tktA FTT_1369c
tktA FTT_1369c
2.2.1.1 Francisella tularensis
3kom_a Q5NF74 100.00 1.50E-34 1.10E-38 350.80 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
tkt BTH_I1195
tkt BTH_I1195
2.2.1.1 Burkholderia thailandensis
3uk1_b Q2SZA7 100.00 8.30E-36 6.00E-40 363.40 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
tktA LSL_1946
tktA LSL_1946
2.2.1.1 Lactobacillus salivarius
4c7v_a Q1WQU8 100.00 1.50E-40 1.10E-44 404.40 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
tkt Cj1645
tkt Cj1645
2.2.1.1 Campylobacter jejuni
3l84_a Q0P7Y3 100.00 1.10E-34 7.80E-39 350.30 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
tkt Rv1449c MTCY493.05
Transketolase (TK) (EC 2.2.1.1)
2.2.1.1 Mycobacterium tuberculosis
3rim_d P9WG25 99.90 8.90E-33 6.50E-37 337.40 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
dxs yajP b0420 JW0410
1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)
2.2.1.7 Escherichia coli
2o1s_a P77488 100.00 6.00E-35 4.40E-39 352.20 0 0 0 0 0 0 0 1
YIL125W KGD1 SGDID:S000001387
pdhA
Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1)
1.2.4.1 Geobacillus stearothermophilus
1w85_a P21873 100.00 1.20E-49 8.60E-54 434.90 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
TKT
Transketolase (TK) (EC 2.2.1.1)
2.2.1.1 Homo sapiens
Short Stature, Developmental Delay, And Congenital Heart Defects,Pfeiffer Syndrome,Lung Cancer Susceptibility 3,Leukemia, Chronic Myeloid,Cerebral Angioma,Colon Adenocarcinoma,Wernicke Encephalopathy,Cataract,Megaloblastic Anemia,Ovarian Cancer,Patent Foramen Ovale,Malignant Astrocytoma,Beriberi,Colorectal Cancer,Human Immunodeficiency Virus Type 1,Wernicke-Korsakoff Syndrome,Transaldolase Deficiency,Nasopharyngeal Carcinoma,Leukemia, Chronic Lymphocytic,Thiamine Deficiency Disease,Wet Beriberi,Dry Beriberi,Lung Cancer,3-Methylglutaconic Aciduria, Type Iii
3mos_a P29401 ENSG00000163931 TKT 100.00 5.50E-38 4.00E-42 378.10 1 1 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
tktA tkt b2935 JW5478
Transketolase 1 (TK 1) (EC 2.2.1.1)
2.2.1.1 Escherichia coli
1qgd_b P27302 100.00 1.30E-34 9.80E-39 351.30 0 0 0 0 0 0 0 1
YIL125W KGD1 SGDID:S000001387
TKL1 YPR074C YP9499.29C
Transketolase 1 (TK 1) (EC 2.2.1.1)
2.2.1.1 Saccharomyces cerevisiae
1tka_a P23254 100.00 4.50E-38 3.30E-42 382.80 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
pdhA
Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1)
1.2.4.1 Geobacillus stearothermophilus
1w85_g P21873 100.00 3.10E-37 2.20E-41 342.80 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)
1.2.4.4 Homo sapiens
Amino Acid Metabolic Disorder,Branched-Chain Keto Acid Dehydrogenase Kinase Deficiency,Intermediate Maple Syrup Urine Disease,Methylmalonic Acidemia,Propionic Acidemia,Maple Syrup Urine Disease,Organic Acidemia
2bfd_a P12694 ENSG00000248098 BCKDHA 100.00 2.10E-42 1.50E-46 387.60 1 1 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
sucA b0726 JW0715
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
1.2.4.2 Escherichia coli
2jgd_a P0AFG3 100.00 2.00E-117 1.00E-121 1109.70 0 0 0 0 0 0 0 1
YIL125W KGD1 SGDID:S000001387
PDHA1 PHE1A
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
1.2.4.1 Homo sapiens
Episodic Ataxia,Leigh Syndrome With Leukodystrophy,Periventricular Leukomalacia,Dystonia,Marshall-Smith Syndrome,Lactic Acidosis,Pyruvate Dehydrogenase E3-Binding Protein Deficiency,Coffin-Lowry Syndrome,Mitochondrial Complex I Deficiency, Nuclear Type 1,Alpha-Ketoglutarate Dehydrogenase Deficiency,Pyruvate Dehydrogenase E1-Alpha Deficiency,Leigh Syndrome
2ozl_a P08559 ENSG00000131828 PDHA1 100.00 8.00E-38 5.70E-42 347.60 1 1 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
NGK_0759
NGK_0759
2.2.1.1 Neisseria gonorrhoeae
5vrb_b B4RKU9 100.00 2.80E-36 2.10E-40 366.20 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
TRK1 CHLRE_02g080200v5 CHLREDRAFT_141319
TRK1 CHLRE_02g080200v5 CHLREDRAFT_141319
2.2.1.1 Chlamydomonas reinhardtii
5nd6_b A8IAN1 100.00 8.40E-37 6.10E-41 371.20 0 0 0 0 0 0 0 0
YIL125W KGD1 SGDID:S000001387
kgd sucA MSMEG_5049 MSMEI_4922
Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
1.2.4.2,2.2.1.5,2.3.1.61,4.1.1.71, Mycolicibacterium smegmatis
2y0p_c A0R2B1 100.00 8.00E-101 6.00E-105 955.30 0 0 0 0 0 0 0 0

Weizmann Institute of Science | Maya Schuldiner Lab