| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YKL017C | HCS1 | SGDID:S000001500 | UPF1 KIAA0221 RENT1 |
Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) |
3.6.4.- | Homo sapiens | Spinal Muscular Atrophy,Autosomal Recessive Distal Hereditary Motor Neuronopathy,Long Qt Syndrome,Waardenburg Syndrome, Type 4b,Pancreatic Adenosquamous Carcinoma,Amyotrophic Lateral Sclerosis 4, Juvenile,Waardenburg Syndrome, Type 4a,Epidermolysis Bullosa, Junctional, Non-Herlitz Type,Disease Of Mental Health,Spinal Muscular Atrophy, Distal, Autosomal Recessive, 1,Coffin-Siris Syndrome 1,Choroideremia,Atrial Septal Defect 2,Ullrich Congenital Muscular Dystrophy 1 |
2xzo_a | Q92900 | ENSG00000005007 | UPF1 | 100.00 | 4.30E-41 | 5.10E-45 | 354.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKL017C | HCS1 | SGDID:S000001500 | SEN1 YLR430W L9576.1 |
Helicase SEN1 (EC 3.6.4.-) (tRNA-splicing endonuclease positive effector) |
3.6.4.- | Saccharomyces cerevisiae | 5mzn_a | Q00416 | 100.00 | 2.60E-38 | 2.90E-42 | 345.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YKL017C | HCS1 | SGDID:S000001500 | NAM7 IFS2 MOF4 UPF1 YMR080C YM9582.05C |
ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1) |
3.6.4.- | Saccharomyces cerevisiae | 2xzl_a | P30771 | 100.00 | 1.90E-42 | 1.90E-46 | 386.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YKL017C | HCS1 | SGDID:S000001500 | AQR KIAA0560 |
RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) |
3.6.4.13 | Homo sapiens | Robinow Syndrome, Autosomal Recessive 1,Retinitis Pigmentosa 26,Noonan Syndrome 1,Retinitis Pigmentosa 22,Histiocytosis-Lymphadenopathy Plus Syndrome,Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 2,Acrofacial Dysostosis,Acrofacial Dysostosis 1, Nager Type,Retinitis Pigmentosa 14 |
4pj3_a | O60306 | ENSG00000021776 | AQR | 99.90 | 3.10E-29 | 3.00E-33 | 296.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKL017C | HCS1 | SGDID:S000001500 | DUF2075 |
Uncharacterized conserved protein (DUF2075) |
pfam Family | PF09848 | 99.50 | 4.60E-19 | 5.60E-23 | 171.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| YKL017C | HCS1 | SGDID:S000001500 | Dna2 Dna2l Kiaa0083 |
DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] |
3.1.-.-,3.6.4.12, | Mus musculus | 5ean_a | Q6ZQJ5 | 100.00 | 5.10E-41 | 5.60E-45 | 381.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YKL017C | HCS1 | SGDID:S000001500 | IGHMBP2 SMBP2 SMUBP2 |
DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) |
3.6.4.13 | Homo sapiens | Spinal Muscular Atrophy With Lower Extremity Predominance,Adult Respiratory Distress Syndrome,Myopathy,Progressive Multifocal Leukoencephalopathy,Neuromuscular Disease,Amyotrophic Lateral Sclerosis 1,Neuronopathy, Distal Hereditary Motor, Type Iib,Spinal Muscular Atrophy,Charcot-Marie-Tooth Disease Type 2a2a,Muscular Atrophy,Anterior Horn Cell Disease,Autosomal Recessive Distal Hereditary Motor Neuronopathy,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Distal Hereditary Motor Neuronopathy Type 2,Motor Peripheral Neuropathy,Charcot-Marie-Tooth Hereditary Neuropathy,Diaphragmatic Eventration,Neuropathy,Charcot-Marie-Tooth Disease,Amyotrophic Lateral Sclerosis 4, Juvenile,Polyneuropathy,Neonatal Myasthenia Gravis,Autosomal Dominant Intermediate Charcot-Marie-Tooth,Tooth Disease,Respiratory Failure,Spinal Muscular Atrophy, Distal, Autosomal Recessive, 1,Scapuloperoneal Spinal Muscular Atrophy,Brown-Vialetto-Van Laere Syndrome,Spinal Muscular Atrophy, X-Linked 2,Neuropathy, Hereditary Sensory And Autonomic, Type Iia,Childhood Spinal Muscular Atrophy,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Ptosis,Spinal Muscular Atrophy, Type I,Spinal Muscular Atrophy, Type Iii,Spinal Muscular Atrophy, Type Ii,Charcot-Marie-Tooth Disease, Axonal, Type 2t,Neuronopathy, Distal Hereditary Motor, Type Va |
4b3f_x | P38935 | ENSG00000132740 | IGHMBP2 | 100.00 | 6.40E-57 | 7.60E-61 | 479.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKL017C | HCS1 | SGDID:S000001500 | cwf11 SPBC646.02 |
Pre-mRNA-splicing factor cwf11 (Complexed with cdc5 protein 11) |
Schizosaccharomyces pombe | 3jb9_x | O94508 | 99.90 | 4.40E-28 | 4.50E-32 | 282.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YKL017C | HCS1 | SGDID:S000001500 | orf1ab |
orf1ab |
2.7.7.48,3.4.19.12,3.4.22.69,3.6.4.12,3.6.4.13 | Human betacoronavirus | 5wwp_a | K0BWD0 | 99.70 | 2.40E-21 | 2.50E-25 | 208.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |