| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YKL032C | IXR1 | SGDID:S000001515 | TFAM TCF6 TCF6L2 |
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2) |
Homo sapiens | Mitochondrial Dna Depletion Syndrome,Myopathy,Optic Nerve Disease,Diabetes Mellitus,Alzheimer Disease,Mitochondrial Myopathy,Mitochondrial Dna Depletion Syndrome 15,Chronic Progressive External Ophthalmoplegia,Dilated Cardiomyopathy,Sensorineural Hearing Loss,Autosomal Dominant Progressive External Ophthalmoplegia,Optic Atrophy 1,Mitochondrial Dna Maintenance Defects,Mitochondrial Disorders,Skin Carcinoma In Situ,Cholestasis,Cranial Nerve Disease,Extrahepatic Cholestasis,Parkinson Disease, Late-Onset,Body Mass Index Quantitative Trait Locus 11,Myasthenic Syndrome, Congenital, 12,Bacterial Gastritis,Perrault Syndrome,Huntington Disease,Leber Hereditary Optic Neuropathy, Modifier Of,Mitochondrial Dna Depletion Syndrome 3,Mitochondrial Dna Depletion Syndrome 4a,Aging,Kearns-Sayre Syndrome,Leigh Syndrome,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes,Myoclonic Epilepsy Associated With Ragged-Red Fibers,Neuropathy, Ataxia, And Retinitis Pigmentosa,Oncocytoma |
3tq6_a | Q00059 | ENSG00000108064 | TFAM | 99.60 | 3.50E-20 | 3.80E-24 | 170.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YKL032C | IXR1 | SGDID:S000001515 | PMS1 PMSL1 |
PMS1 protein homolog 1 (DNA mismatch repair protein PMS1) |
Homo sapiens | Cowden Syndrome,Muir-Torre Syndrome,Urachus Cancer,Hereditary Nonpolyposis Colon Cancer,Sebaceous Adenocarcinoma,Rectum Signet Ring Adenocarcinoma,Ovarian Cancer,Hereditary Breast Ovarian Cancer Syndrome,Colorectal Cancer,Sebaceous Gland Neoplasm,Lynch Syndrome I,Meier-Gorlin Syndrome 2,Lynch Syndrome,Familial Adenomatous Polyposis,Colorectal Cancer, Hereditary Nonpolyposis, Type 6,Colorectal Cancer, Hereditary Nonpolyposis, Type 4,Miller-Dieker Lissencephaly Syndrome,Epilepsy, Idiopathic Generalized 9 |
2cs1_a | P54277 | ENSG00000064933 | PMS1 | 98.30 | 1.30E-10 | 1.50E-14 | 89.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YKL032C | IXR1 | SGDID:S000001515 | HMGB3 HMG2A HMG4 |
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4) |
Homo sapiens | Colobomatous Microphthalmia,Microphthalmia,Terminal Osseous Dysplasia,Microphthalmia, Syndromic 13,Linear Skin Defects With Multiple Congenital Anomalies 1 |
2eqz_a | O15347 | ENSG00000029993 | HMGB3 | 98.30 | 1.50E-10 | 1.80E-14 | 86.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YKL032C | IXR1 | SGDID:S000001515 | KMT2C HALR KIAA1506 MLL3 |
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.354) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3) |
2.1.1.354 | Homo sapiens | Plasma Cell Neoplasm,Kleefstra Syndrome,Leukemia,Leukemia, Acute Myeloid,Kleefstra Syndrome Due To A Point Mutation,Cystic Kidney Disease,Colorectal Cancer,Microcephaly,Alacrima, Achalasia, And Mental Retardation Syndrome,Kleefstra Syndrome 2,Disease Of Mental Health,Kleefstra Syndrome 1,Autism Spectrum Disorder,Kabuki Syndrome 1,Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome,Nut Midline Carcinoma,Myeloma, Multiple,Cardiomyopathy, Infantile Histiocytoid |
2yuk_a | Q8NEZ4 | ENSG00000055609 | KMT2C | 98.60 | 1.30E-11 | 1.20E-15 | 102.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKL032C | IXR1 | SGDID:S000001515 | ABF2 HIM1 YMR072W YM9916.11 |
ARS-binding factor 2, mitochondrial |
Saccharomyces cerevisiae | 5jh0_d | Q02486 | 99.70 | 4.50E-23 | 5.20E-27 | 179.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YKL032C | IXR1 | SGDID:S000001515 | Hmgb1 Hmg-1 Hmg1 |
High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility group protein 1) (HMG-1) |
Rattus norvegicus | 2gzk_a | P63159 | ENSG00000184895 | SRY | 99.70 | 5.00E-22 | 6.10E-26 | 168.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YKL032C | IXR1 | SGDID:S000001515 | HBP1 |
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1) |
Homo sapiens | 46,Xx Sex Reversal 3,Developmental And Epileptic Encephalopathy 1 |
2e6o_a | O60381 | ENSG00000105856 | HBP1 | 98.50 | 2.20E-11 | 2.60E-15 | 93.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YKL032C | IXR1 | SGDID:S000001515 | MAEL |
Protein maelstrom homolog |
Homo sapiens | Retinitis Pigmentosa 49,Brooke-Spiegler Syndrome |
2cto_a | Q96JY0 | ENSG00000143194 | MAEL | 98.40 | 5.50E-11 | 6.30E-15 | 93.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YKL032C | IXR1 | SGDID:S000001515 | UBTF UBF UBF1 |
Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1) |
Homo sapiens | Retinitis Pigmentosa,Rare Syndromic Intellectual Disability,Warsaw Breakage Syndrome,Neurodegeneration, Childhood-Onset, With Brain Atrophy,Limited Scleroderma,Retinoblastoma,Muscle Hypertrophy,Syndromic Intellectual Disability,Treacher Collins Syndrome 1,Retinitis Pigmentosa 11 |
1k99_a | P17480 | 99.00 | 2.90E-14 | 2.90E-18 | 117.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YKL032C | IXR1 | SGDID:S000001515 | Tox |
Thymocyte selection-associated high mobility group box protein TOX (Thymus high mobility group box protein TOX) |
Mus musculus | 2co9_a | Q66JW3 | 98.40 | 7.20E-11 | 8.60E-15 | 92.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |