| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YKR017C | HEL1 | SGDID:S000001725 | PML MYL PP8675 RNF71 TRIM19 |
Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19) |
Homo sapiens | Leukemia, Chronic Myeloid,Primary Biliary Cholangitis,Leukemia,Leukemia, Acute Myeloid,Leukemia, Acute Lymphoblastic,Influenza,Herpes Simplex,Breast Cancer,Neuronal Intranuclear Inclusion Disease,Rabies,Dentatorubral-Pallidoluysian Atrophy,Acute Promyelocytic Leukemia,Nijmegen Breakage Syndrome,Mulibrey Nanism,Bloom Syndrome |
1bor_a | P29590 | 97.30 | 3.00E-07 | 2.10E-11 | 63.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YKR017C | HEL1 | SGDID:S000001725 | PRKN2 LOC105225264 |
PRKN2 LOC105225264 |
Bactrocera dorsalis | 6djw_a | A0A034W4L8 | 98.30 | 1.90E-10 | 1.40E-14 | 113.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YKR017C | HEL1 | SGDID:S000001725 | 8230172 Phum_PHUM233570 |
8230172 Phum_PHUM233570 |
2.3.2.- | Pediculus humanus | 5caw_a | E0VIU9 | 99.80 | 5.50E-25 | 4.00E-29 | 218.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YKR017C | HEL1 | SGDID:S000001725 | PRKN PARK2 |
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2) |
2.3.2.31 | Homo sapiens | Progressive Myoclonus Epilepsy,Supranuclear Palsy, Progressive, 1,Retinitis Pigmentosa,Rem Sleep Behavior Disorder,Lung Cancer Susceptibility 3,Tremor,Optic Nerve Disease,Prion Disease,Gaucher'S Disease,Sphingolipidosis,Alzheimer Disease,Ulnar Nerve Lesion,Radial Nerve Lesion,Amyotrophic Lateral Sclerosis 1,Angelman Syndrome,Motor Neuron Disease,Movement Disease,Neurodegeneration With Brain Iron Accumulation,Testicular Disease,Leber Plus Disease,Essential Tremor,Choreatic Disease,Machado-Joseph Disease,Dementia,Optic Atrophy 1,Cerebellar Disease,Leukoencephalopathy, Hereditary Diffuse, With Spheroids,Parkin Type Of Early-Onset Parkinson Disease,Dystonia,Nervous System Disease,Ovarian Cancer,Charcot-Marie-Tooth Disease,Paratyphoid Fever,Parkinson Disease, Late-Onset,Peripheral Nervous System Disease,Parkinson Disease 3, Autosomal Dominant,Parkinson Disease 1, Autosomal Dominant,Tooth Disease,Pick Disease Of Brain,Postencephalitic Parkinson Disease,Autosomal Dominant Cerebellar Ataxia,Fanconi Anemia, Complementation Group A,Disease Of Mental Health,Gaucher Disease, Type I,Toxic Encephalopathy,Body Mass Index Quantitative Trait Locus 11,Dentatorubral-Pallidoluysian Atrophy,Meier-Gorlin Syndrome 2,Dementia, Lewy Body,Dystonia 12,Schizophrenia,Ophthalmomyiasis,Restless Legs Syndrome,Parkinson Disease 21,Kufor-Rakeb Syndrome,Leprosy 3,Focal Dystonia,Parkinson Disease 10,Attention Deficit-Hyperactivity Disorder,Autism Spectrum Disorder,Multiple System Atrophy 1,Color Agnosia,Leber Hereditary Optic Neuropathy, Modifier Of,Leprosy 2,Mitochondrial Complex I Deficiency, Nuclear Type 1,Epilepsy, Idiopathic Generalized 9,Ptosis,Rett Syndrome,Myoclonic Epilepsy Of Lafora,Autism,Juvenile-Onset Parkinson'S Disease,Early-Onset Parkinson'S Disease,Parkinson Disease 2, Autosomal Recessive Juvenile,Lung Cancer,Parkinson Disease 15, Autosomal Recessive Early-Onset |
4i1f_a | O60260 | ENSG00000185345 | PRKN | 99.80 | 2.80E-25 | 2.00E-29 | 221.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKR017C | HEL1 | SGDID:S000001725 | MYCBP2 KIAA0916 PAM |
E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc) |
2.3.2.33 | Homo sapiens | Cerebral Degeneration,Reticulate Acropigmentation Of Kitamura,Pelizaeus-Merzbacher Disease,Hypomyelinating Leukodystrophy |
5o6c_a | O75592 | ENSG00000005810 | MYCBP2 | 99.20 | 1.40E-15 | 1.00E-19 | 145.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKR017C | HEL1 | SGDID:S000001725 | park parkin CG10523 |
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) |
2.3.2.31 | Drosophila melanogaster | 2lwr_a | Q7KTX7 | 97.80 | 1.50E-08 | 1.10E-12 | 74.00 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
| YKR017C | HEL1 | SGDID:S000001725 | RNF31 ZIBRA |
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein) |
2.3.2.31 | Homo sapiens | Autoinflammation, Panniculitis, And Dermatosis Syndrome,Immunodeficiency 11,Glycogen Storage Disease Iv,Polyglucosan Body Myopathy 1 With Or Without Immunodeficiency,Tooth Agenesis,Incontinentia Pigmenti |
4ljo_a | Q96EP0 | ENSG00000092098 | RNF31 | 97.50 | 1.10E-07 | 7.50E-12 | 85.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKR017C | HEL1 | SGDID:S000001725 | TRAF6 RNF85 |
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6) |
2.3.2.27 | Homo sapiens | Diabetes Mellitus,Ectodermal Dysplasia,B-Cell Lymphoma,Toxoplasmosis,Noonan Syndrome 1,Paget'S Disease Of Bone,Osteoporosis,Osteopetrosis,Cone-Rod Dystrophy 2,Type 2 Diabetes Mellitus,Streptococcus Pneumonia,Ectodermal Dysplasia 10a, Hypohidrotic/Hair/Nail Type, Autosomal Dominant,Malaria,Inflammatory Bowel Disease,Tooth Agenesis,Lymphoma, Mucosa-Associated Lymphoid Type,Immunodeficiency With Hyper-Igm, Type 3,Lymphoma,Incontinentia Pigmenti,Systemic Lupus Erythematosus,Lung Cancer |
3hcs_b | Q9Y4K3 | ENSG00000175104 | TRAF6 | 97.20 | 3.70E-07 | 2.80E-11 | 78.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YKR017C | HEL1 | SGDID:S000001725 | ARIH1 ARI MOP6 UBCH7BP HUSSY-27 |
E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1) |
2.3.2.31 | Homo sapiens | Parkinson Disease, Late-Onset,Glycogen Storage Disease Iv,Meester-Loeys Syndrome,Juvenile-Onset Parkinson'S Disease |
5udh_a | Q9Y4X5 | ENSG00000166233 | ARIH1 | 100.00 | 1.60E-49 | 1.20E-53 | 419.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |