| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YLR035C-A | YLR035C-A | SGDID:S000007225 | pol |
Exoribonuclease H (EC 2.7.7.49) (EC 3.1.13.2) (EC 3.1.26.13) (Integrase) (Protease) (Retropepsin) (Reverse transcriptase/ribonuclease H) (Fragment) |
2.7.7.49,3.1.13.2,3.1.26.13 | Simian immunodeficiency virus | 1c6v_a | Q88016 | 99.20 | 2.30E-15 | 2.00E-19 | 150.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | PSIP1 DFS70 LEDGF PSIP2 |
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) |
Homo sapiens | Cataract,Dermatitis, Atopic,Multiple Endocrine Neoplasia, Type I,Immune Deficiency Disease |
3f9k_i | O75475 | ENSG00000164985 | PSIP1 | 98.40 | 4.50E-11 | 4.60E-15 | 117.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; Capsid protein p27, alternate cleaved 1; Capsid protein p27, alternate cleaved 2; p3; Nucleocapsid protein p12; Protease p15 (EC 3.4.23.-); Reverse transcriptase beta-subunit (RT-beta); Reverse transcriptase alpha-subunit (RT-alpha) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (pp32); p4] |
2.7.7.49,2.7.7.7,3.1.26.4 | Rous sarcoma | 1asu_a | O92956 | 98.10 | 8.20E-10 | 8.50E-14 | 102.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; Capsid protein p27, alternate cleaved 1; Capsid protein p27, alternate cleaved 2; Spacer peptide (SP) (p3); Nucleocapsid protein p12; Protease p15 (EC 3.4.23.-); Reverse transcriptase beta-subunit (RT-beta); Reverse transcriptase alpha-subunit (RT-alpha) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (pp32); p4] |
2.7.7.49,2.7.7.7,3.1.26.4 | Rous sarcoma | 4fw1_a | P03354 | 98.90 | 3.80E-13 | 3.70E-17 | 137.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10-Pol (NC-pol); Protease (PR) (EC 3.4.23.-) (p14); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p80); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p46)] |
2.7.7.49,2.7.7.7,3.1.26.4 | Moloney murine | 1qaj_a | P03355 | 98.30 | 2.60E-10 | 2.60E-14 | 117.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] |
2.7.7.49,2.7.7.7,3.1.13.2,3.1.26.13,3.4.23.16 | Human immunodeficiency | 2hmi_b | P03366 | 99.80 | 1.90E-23 | 1.80E-27 | 239.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.47) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] |
2.7.7.49,2.7.7.7,3.1.13.2,3.1.26.13,3.4.23.47 | Human immunodeficiency | 1mu2_a | P04584 | 99.50 | 1.30E-18 | 1.20E-22 | 204.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] |
2.7.7.49,2.7.7.7,3.1.13.2,3.1.26.13,3.4.23.16 | Human immunodeficiency | 1b9d_a | P12497 | 97.90 | 5.50E-09 | 5.70E-13 | 97.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | pol |
Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)] |
2.7.7.49,2.7.7.7,3.1.26.4 | Human spumaretrovirus | 2x6n_a | P14350 | 98.00 | 2.90E-09 | 3.00E-13 | 103.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | pol |
Pol polyprotein [Cleaved into: Protease (Retropepsin) (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2); Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] |
2.7.7.49,3.1.13.2,3.1.26.13,3.6.1.23, | Feline immunodeficiency | 4pa1_a | P16088 | 97.60 | 2.50E-08 | 2.60E-12 | 90.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | gag-pol |
Gag-Pol polyprotein (Pr170Gag-Pol) [Cleaved into: Matrix protein p16 (MA); p2L; Capsid protein p26 (CA); p3; Transframe peptide (p11); Protease (EC 3.4.23.-) (P119) (Retropepsin); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (P72); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] |
2.7.7.49,2.7.7.7,3.1.13.2,3.1.26.13, | Bovine immunodeficiency | 3kks_b | P19560 | 97.70 | 1.50E-08 | 1.60E-12 | 92.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | pol |
pol |
2.7.7.49,3.1.13.2,3.1.26.13 | Human immunodeficiency | 3l3u_a | Q72498 | 97.90 | 5.00E-09 | 5.10E-13 | 97.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | pol |
pol |
2.7.7.49,3.1.13.2,3.1.26.13 | Simian immunodeficiency | 1c6v_b | Q88016 | 97.90 | 5.80E-09 | 6.00E-13 | 96.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YLR035C-A | YLR035C-A | SGDID:S000007225 | TY3B-G YGRWTy3-1 POL YGR109W-B G5984 |
Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] |
2.7.7.49,2.7.7.7, | Saccharomyces cerevisiae | 4ol8_b | Q99315 | 100.00 | 7.50E-37 | 7.20E-41 | 356.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |