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AnalogYeast
One stop shop for finding analogs for your favorite yeast protein

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YLR174W IDP2 / SGDID:S000004164
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YLR174W IDP2 SGDID:S000004164
leuB
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Bacillus coagulans
1v5b_b P12010 100.00 7.70E-76 5.40E-80 558.00 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Acidithiobacillus ferrooxidans
1a05_b Q56268 100.00 1.50E-78 1.10E-82 574.50 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IDH2
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Homo sapiens
Adult Hepatocellular Carcinoma,Retinitis Pigmentosa,Brain Stem Glioma,Chondrosarcoma,Plasma Cell Neoplasm,Connective Tissue Cancer,Bone Sarcoma,Gemistocytic Astrocytoma,Protoplasmic Astrocytoma,Oligoastrocytoma,Anaplastic Oligodendroglioma,Sinonasal Undifferentiated Carcinoma,Low Grade Glioma,Essential Thrombocythemia,Biliary Tract Disease,Enchondroma,Adult Brain Stem Glioma,Diffuse Astrocytoma,Angioimmunoblastic T-Cell Lymphoma,Bile Duct Adenocarcinoma,Intracranial Chondrosarcoma,Intrahepatic Cholangiocarcinoma,Mixed Oligodendroglioma-Astrocytoma,Glioma,Leukemia, Acute Myeloid,Spindle Cell Hemangioma,Bone Marrow Cancer,Hemangioma,Mixed Glioma,Juxtacortical Chondroma,Combined D-2- And L-2-Hydroxyglutaric Aciduria,Brain Cancer,Enchondromatosis, Multiple, Ollier Type,Myeloid Leukemia,Glioblastoma,Squamous Cell Carcinoma, Head And Neck,Malignant Astrocytoma,High Grade Glioma,Gliosarcoma,Giant Cell Glioblastoma,Adult Astrocytic Tumour,Anaplastic Astrocytoma,Colorectal Cancer,Cytogenetically Normal Acute Myeloid Leukemia,Hepatocellular Carcinoma,Anaplastic Oligoastrocytoma,Periosteal Chondrosarcoma,Clear Cell Chondrosarcoma,Oligodendroglioma,Childhood Oligodendroglioma,Adult Oligodendroglioma,Pheochromocytoma,Chondroblastic Osteosarcoma,D-2-Hydroxyglutaric Aciduria 2,Systemic Mastocytosis,Cholangiocarcinoma,Central Nervous System Cancer,L-2-Hydroxyglutaric Aciduria,2-Hydroxyglutaric Aciduria,Myelodysplastic Syndrome,Glioma Susceptibility 1,Mature T-Cell And Nk-Cell Lymphoma,Multiple Enchondromatosis, Maffucci Type,Brain Glioma,Li-Fraumeni Syndrome,Myelofibrosis,Myeloma, Multiple,Spinal Disease,Childhood Acute Myeloid Leukemia,Lung Cancer,D-2-Hydroxyglutaric Aciduria 1,Polycythemia Vera
4ja8_a P48735 ENSG00000182054 IDH2 100.00 1.50E-83 1.00E-87 617.50 1 1 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB Cj1718c
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Campylobacter jejuni
3udu_b Q9PLW0 100.00 1.00E-78 7.00E-83 575.30 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IDH1 PICD
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Homo sapiens
Adult Hepatocellular Carcinoma,Supratentorial Cancer,Skin Melanoma,Cerebral Convexity Meningioma,Gliomatosis Cerebri,Bile Duct Disease,Brain Stem Glioma,Brain Stem Cancer,Cerebellum Cancer,Lung Cancer Susceptibility 3,Childhood Brain Stem Glioma,Adenoid Cystic Carcinoma,Chondrosarcoma,Bone Cancer,Suppression Of Tumorigenicity 12,Melanoma,Plasma Cell Neoplasm,Internal Auditory Canal Lipoma,Metaphyseal Enchondromatosis With D-2-Hydroxyglutaric Aciduria,Connective Tissue Cancer,Bone Sarcoma,Frontal Lobe Neoplasm,Juvenile Pilocytic Astrocytoma,Childhood Pilocytic Astrocytoma,Diffuse Midline Glioma, H3 K27m-Mutant,Gemistocytic Astrocytoma,Mucinous Intrahepatic Cholangiocarcinoma,Atypical Teratoid Rhabdoid Tumor,Temporal Lobe Neoplasm,Low Grade Glioma,Essential Thrombocythemia,Astroblastoma,Biliary Tract Disease,Myeloproliferative Neoplasm,Enchondroma,Infratentorial Cancer,Supratentorial Primitive Neuroectodermal Tumor,Adult Brain Stem Glioma,Benign Ependymoma,Pilomyxoid Astrocytoma,Cerebellar Astrocytoma,Pilocytic Astrocytoma,Pleomorphic Xanthoastrocytoma,Pilocytic Astrocytoma Of Cerebellum,Gliofibroma,Diffuse Astrocytoma,Spinal Cord Astrocytoma,Bile Duct Adenocarcinoma,Klatskin'S Tumor,Intracranial Chondrosarcoma,Intrahepatic Cholangiocarcinoma,Mixed Oligodendroglioma-Astrocytoma,Glioma,Frontal Convexity Meningioma,Leukemia, Acute Myeloid,Spindle Cell Hemangioma,Bone Marrow Cancer,Hemangioma,High Grade Ependymoma,Angiocentric Glioma,High-Grade Astrocytoma,Low-Grade Astrocytoma,Mixed Glioma,Extraventricular Neurocytoma,Juxtacortical Chondroma,Dysembryoplastic Neuroepithelial Tumor,Brain Cancer,Enchondromatosis, Multiple, Ollier Type,Laryngeal Neuroendocrine Tumor,Clear Cell Ependymoma,Myeloid Leukemia,Spinal Cancer,Breast Cancer,Glioblastoma,Malignant Astrocytoma,High Grade Glioma,Gliosarcoma,Giant Cell Glioblastoma,Adult Astrocytic Tumour,Anaplastic Astrocytoma,Juvenile Astrocytoma,Colorectal Cancer,Nervous System Cancer,Cytogenetically Normal Acute Myeloid Leukemia,Hepatocellular Carcinoma,Periosteal Chondrosarcoma,Oligodendroglioma,Childhood Oligodendroglioma,Spinal Cord Oligodendroglioma,Spinal Cord Glioma,Adult Oligodendroglioma,Chondroblastic Osteosarcoma,Breast Adenocarcinoma,Cholangiocarcinoma,Cerebral Ventricle Cancer,Central Nervous System Cancer,Alpha-Thalassemia,Cerebrum Cancer,Adult Central Nervous System Primitive Neuroectodermal Neoplasm,Bladder Urothelial Carcinoma,L-2-Hydroxyglutaric Aciduria,2-Hydroxyglutaric Aciduria,Myelodysplastic Syndrome,Glioma Susceptibility 1,Multiple Enchondromatosis, Maffucci Type,Uterine Corpus Endometrial Carcinoma,Central Nervous System Benign Neoplasm,Brain Glioma,Li-Fraumeni Syndrome,Myelofibrosis,Myeloma, Multiple,Medulloblastoma,Spinal Disease,Childhood Acute Myeloid Leukemia,Lung Cancer,D-2-Hydroxyglutaric Aciduria 1,Polycythemia Vera
1t0l_c O75874 ENSG00000138413 IDH1 100.00 4.80E-82 3.30E-86 608.00 1 1 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB Saci_0600
leuB Saci_0600
1.1.1.85 Sulfolobus acidocaldarius
4y1p_a Q4JB37 100.00 2.90E-79 2.00E-83 573.70 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
icd TTHA1535
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Thermus thermophilus
2d1c_b P33197 100.00 1.10E-81 7.60E-86 608.20 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
icd
icd
1.1.1.42 Acidithiobacillus thiooxidans
2d4v_b Q8GAX0 100.00 3.00E-76 2.10E-80 566.10 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
lys12 SPAC31G5.04
Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87)
1.1.1.87 Schizosaccharomyces pombe
3ty3_a O14104 100.00 2.20E-78 1.50E-82 572.80 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB BTH_II0674
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Burkholderia thailandensis
4iwh_a Q2T7H6 100.00 3.20E-78 2.20E-82 572.80 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IDH1 YNL037C N2690
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
1.1.1.41 Saccharomyces cerevisiae
3blx_e P28834 100.00 1.70E-76 1.20E-80 558.60 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
DP0778
DP0778
1.1.1.42 Desulfotalea psychrophila
2uxq_b Q6AQ66 100.00 2.20E-80 1.50E-84 596.00 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
Cthe_0285
Cthe_0285
1.1.1.42 Hungateiclostridium thermocellum
4aou_a A3DC45 100.00 5.10E-80 3.50E-84 592.90 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IMDH2 IMD2 IMDH IPMDH2 At1g80560 T21F11.11
3-isopropylmalate dehydrogenase 2, chloroplastic (3-IPM-DH 2) (AtIMDH2) (AtIMDH3) (IMDH 2) (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (Isopropylmalate dehydrogenase 2) (AtIMD2)
1.1.1.85 Arabidopsis thaliana
5j32_a P93832 100.00 4.20E-79 2.90E-83 583.60 0 0 0 0 0 0 1 0
YLR174W IDP2 SGDID:S000004164
IDP1 YDL066W
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Saccharomyces cerevisiae
2qfw_d P21954 100.00 4.60E-84 3.20E-88 623.10 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
TK0280
TK0280
Thermococcus kodakarensis
5hn3_a Q5JFV8 100.00 7.20E-78 5.00E-82 564.60 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)
1.1.1.41 Homo sapiens
Retinitis Pigmentosa,Inhibited Female Orgasm,Cone-Rod Dystrophy 2,2-Hydroxyglutaric Aciduria,Infantile Cerebellar-Retinal Degeneration,Mitochondrial Complex I Deficiency, Nuclear Type 1,Retinitis Pigmentosa 90,D-2-Hydroxyglutaric Aciduria 1
5gri_a P50213 ENSG00000166411 IDH3A 100.00 8.40E-79 5.80E-83 571.60 1 1 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
TM_1148
TM_1148
1.1.1.42 Thermotoga maritima
1zor_a Q9X0N2 100.00 1.20E-82 8.50E-87 611.20 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
icd icdA icdE b1136 JW1122
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Escherichia coli
1p8f_a P08200 100.00 7.80E-79 5.40E-83 584.00 0 0 0 0 0 0 0 1
YLR174W IDP2 SGDID:S000004164
TTUC
Tartrate dehydrogenase/decarboxylase (TDH) (EC 1.1.1.93) (EC 4.1.1.73) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83)
1.1.1.83,1.1.1.93,4.1.1.73 Pseudomonas putida
3flk_a Q51945 100.00 1.50E-77 1.10E-81 569.40 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
icd citC BSU29130
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Bacillus subtilis
1hqs_b P39126 100.00 1.40E-77 9.30E-82 573.70 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
idh ST2166 STK_21660
idh ST2166 STK_21660
1.1.1.42 Sulfurisphaera tokodaii
2e0c_a Q96YK6 100.00 7.90E-77 5.40E-81 569.50 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
icd AF_0647
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
1.1.1.42 Archaeoglobus fulgidus
2iv0_b O29610 100.00 1.90E-78 1.30E-82 579.90 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
icd BURPS1710b_1108
icd BURPS1710b_1108
1.1.1.42 Burkholderia pseudomallei
3dms_a Q3JV82 100.00 5.10E-76 3.50E-80 565.60 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB b0073 JW5807
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Escherichia coli
1cm7_b P30125 100.00 1.70E-78 1.20E-82 575.10 0 0 0 0 0 0 0 1
YLR174W IDP2 SGDID:S000004164
hicd hdh hicdh TT_C1012
Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87)
1.1.1.87 Thermus thermophilus
1x0l_a Q72IW9 100.00 4.60E-81 3.20E-85 585.60 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB SHEWBE_0188
leuB SHEWBE_0188
1.1.1.85 Shewanella benthica
3vmk_b D2YZL2 100.00 1.10E-77 7.50E-82 569.80 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB Rv2995c MTV012.09
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Mycobacterium tuberculosis
1w0d_b P9WKK9 100.00 6.90E-78 4.80E-82 565.40 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IDH2 YOR136W O3326 YOR3326W
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
1.1.1.41 Saccharomyces cerevisiae
3blv_h P28241 100.00 3.40E-78 2.30E-82 569.60 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB TTHA1230
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Thermus thermophilus
2y3z_a Q5SIY4 100.00 2.70E-80 1.90E-84 586.20 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
leuB
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
1.1.1.85 Acidithiobacillus ferrooxidans
1a05_a Q56268 100.00 8.60E-88 5.90E-92 632.30 0 0 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma)
Homo sapiens
Inhibited Female Orgasm,Intracranial Chondrosarcoma,Juxtacortical Chondroma,D-2-Hydroxyglutaric Aciduria 2,Lubs X-Linked Mental Retardation Syndrome,2-Hydroxyglutaric Aciduria,Multiple Enchondromatosis, Maffucci Type,D-2-Hydroxyglutaric Aciduria 1
5grf_b P51553 ENSG00000067829 IDH3G 100.00 5.30E-76 3.70E-80 554.60 1 1 0 0 0 0 0 0
YLR174W IDP2 SGDID:S000004164
APE_0689.1
APE_0689.1
1.1.1.42 Aeropyrum pernix
1tyo_b Q9YE81 100.00 3.20E-77 2.20E-81 575.30 0 0 0 0 0 0 0 0

Weizmann Institute of Science | Maya Schuldiner Lab