YLR291C GCD7 / SGDID:S000004282
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YLR291C GCD7 SGDID:S000004282
mtnA ykrS BSU13550
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase)
 5.3.1.23 Bacillus subtilis
2yvk_d O31662 100.00 9.60E-59 6.80E-63 436.60 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
EIF2B2 EIF2BB
Translation initiation factor eIF-2B subunit beta (S20I15) (S20III15) (eIF-2B GDP-GTP exchange factor subunit beta)
 Homo sapiens
Childhood Ataxia With Central Nervous System Hypomyelination / Vanishing White Matter,Leukodystrophy,Premature Menopause,Cerebral Degeneration,Mehmo Syndrome,Leukoencephalopathy With Vanishing White Matter,Lynch Syndrome,Combined Saposin Deficiency,Multiple Synostoses Syndrome,Perrault Syndrome,Spastic Ataxia 4
 6caj_c P49770 ENSG00000119718 EIF2B2 100.00 9.20E-59 6.50E-63 437.20 1 1 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
CTHT_0063470
CTHT_0063470
 Chaetomium thermophilum
4zem_a G0SEE6 100.00 1.60E-56 1.10E-60 424.80 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
tif222 SPAC343.14c
Probable translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta)
 Schizosaccharomyces pombe
5b04_c Q9UT76 100.00 7.10E-58 5.00E-62 434.20 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
GCN3 AAS2 TIF221 YKR026C
Translation initiation factor eIF-2B subunit alpha (GCD complex subunit GCN3) (Guanine nucleotide exchange factor subunit GCN3) (Translational activator GCN3) (eIF-2B GDP-GTP exchange factor subunit alpha)
 Saccharomyces cerevisiae
6i3m_a P14741 100.00 1.70E-50 1.20E-54 372.00 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
AF_0370
Putative methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (MTNA-like protein) (aMTNA) (S-methyl-5-thioribose-1-phosphate isomerase)
 5.3.1.23 Archaeoglobus fulgidus
1t5o_a O29877 100.00 2.40E-65 1.60E-69 472.60 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
EIF2B4 EIF2BD
Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)
 Homo sapiens
Childhood Ataxia With Central Nervous System Hypomyelination / Vanishing White Matter,Leukoencephalopathy, Hereditary Diffuse, With Spheroids,Leukodystrophy,Premature Menopause,Glycogen Storage Disease Xv,Cerebral Degeneration,Mehmo Syndrome,Leukoencephalopathy With Vanishing White Matter,Combined Saposin Deficiency,Biotinidase Deficiency
 6caj_e Q9UI10 100.00 1.20E-57 8.10E-62 439.60 1 1 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
PH0702
Putative methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (MTNA-like protein) (aMTNA) (S-methyl-5-thioribose-1-phosphate isomerase)
 5.3.1.23 Pyrococcus horikoshii
6a34_b O58433 100.00 1.20E-52 8.40E-57 394.80 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
LmjF36.4930 LmjF_36_4930
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
 5.3.1.23 Leishmania major
2a0u_a Q4Q0R9 100.00 2.00E-53 1.40E-57 402.20 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
PH0208
Ribose 1,5-bisphosphate isomerase (R15P isomerase) (R15Pi) (EC 5.3.1.29) (Ribulose 1,5-bisphosphate synthase) (RuBP synthase)
 5.3.1.29 Pyrococcus horikoshii
5yfj_a O57947 100.00 5.50E-56 3.90E-60 412.40 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
tif224 SPAC21E11.06
Probable translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)
 Schizosaccharomyces pombe
5b04_h Q09924 100.00 4.40E-59 3.10E-63 446.80 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
AF_0370
Putative methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (MTNA-like protein) (aMTNA) (S-methyl-5-thioribose-1-phosphate isomerase)
 5.3.1.23 Archaeoglobus fulgidus
1t5o_b O29877 100.00 1.50E-54 1.10E-58 405.80 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
mtnA TM_0911
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase)
 5.3.1.23 Thermotoga maritima
1t9k_d Q9X013 100.00 7.00E-53 4.90E-57 393.60 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
GCD7 TIF222 YLR291C L8003.17
Translation initiation factor eIF-2B subunit beta (GCD complex subunit GCD7) (Guanine nucleotide exchange factor subunit GCD7) (eIF-2B GDP-GTP exchange factor subunit beta)
 Saccharomyces cerevisiae
6i3m_f P32502 100.00 4.40E-60 3.10E-64 448.60 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
CTHT_0028980
CTHT_0028980
 Chaetomium thermophilum
4zeo_a G0S811 100.00 5.70E-54 3.90E-58 410.10 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
tif221 SPCC11E10.07c
Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha)
 Schizosaccharomyces pombe
5b04_a Q9USP0 100.00 1.40E-50 9.90E-55 377.60 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
GCD2 TIF224 YGR083C
Translation initiation factor eIF-2B subunit delta (GCD complex subunit GCD2) (Guanine nucleotide exchange factor subunit GCD2) (eIF-2B GDP-GTP exchange factor subunit delta)
 Saccharomyces cerevisiae
6i3m_c P12754 100.00 6.80E-56 4.60E-60 433.20 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
MRI1 MRDI UNQ6390/PRO21135
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
 5.3.1.23 Homo sapiens
Epilepsy,Infantile Epilepsy Syndrome,Epilepsy, Familial Temporal Lobe, 3
 4ldr_b Q9BV20 ENSG00000037757 MRI1 100.00 9.90E-55 7.00E-59 409.80 1 1 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
PH0440
Putative translation initiation factor eIF-2B subunit 2-like (eIF-2B GDP-GTP exchange factor)
 Pyrococcus horikoshii
1vb5_b O58185 100.00 2.40E-45 1.70E-49 333.30 0 0 0 0 0 0 0 0
YLR291C GCD7 SGDID:S000004282
EIF2B1 EIF2BA
Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha)
 Homo sapiens
Type 1 Diabetes Mellitus 22,Childhood Ataxia With Central Nervous System Hypomyelination / Vanishing White Matter,Leukodystrophy,Cerebral Degeneration,Leukoencephalopathy With Vanishing White Matter,Megalencephalic Leukoencephalopathy With Subcortical Cysts 1,Spastic Ataxia 4
 3ecs_c Q14232 100.00 2.50E-53 1.80E-57 391.70 1 1 0 0 0 0 0 0