Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YLR450W | HMG2 | SGDID:S000004442 | HMGR |
HMGR |
Methanothermococcus thermolithotrophicus | 6hr7_b | A0A4V8GZY0 | 100.00 | 1.60E-91 | 1.30E-95 | 800.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLR450W | HMG2 | SGDID:S000004442 | HMGCR |
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34) |
1.1.1.34 | Homo sapiens | Heart Disease,Vascular Disease,Myopathy,Non-Alcoholic Fatty Liver Disease,Familial Hyperlipidemia,Inherited Metabolic Disorder,Diabetes Mellitus,Nephrotic Syndrome,Acute Myocardial Infarction,Homozygous Familial Hypercholesterolemia,Alzheimer Disease,Hepatoblastoma,Myocardial Infarction,Defective Apolipoprotein B-100,Stroke, Ischemic,Myositis,Sitosterolemia,Spondylosis,Smith-Lemli-Opitz Syndrome,Arteriosclerosis,Atherosclerosis Susceptibility,Cardiovascular System Disease,Hyperlipoproteinemia, Type Iii,Osteoporosis,Lichen Planus Pemphigoides,Kidney Disease,Eye Disease,Xanthomatosis,Breast Cancer,Colorectal Cancer,Familial Hypercholesterolemia,Lipid Metabolism Disorder,Clopidogrel Resistance,Peripheral Vascular Disease,Mood Disorder,Breast Adenocarcinoma,Disease Of Mental Health,Schnyder Corneal Dystrophy,Mevalonic Aciduria,Skin Disease,Type 2 Diabetes Mellitus,Multiple Sclerosis,Hemochromatosis, Type 1,Pulmonary Disease, Chronic Obstructive,Hyperlipidemia, Familial Combined, 3,Hypertension, Essential,Lipoprotein Quantitative Trait Locus,3-Methylglutaconic Aciduria,Fetal Akinesia Deformation Sequence 1,Cerebrotendinous Xanthomatosis |
2q6b_a | P04035 | ENSG00000113161 | HMGCR | 100.00 | 1.30E-96 | 1.00E-100 | 843.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YLR450W | HMG2 | SGDID:S000004442 | HMG-CoA_red |
Hydroxymethylglutaryl-coenzyme A reductase |
pfam Family | PF00368 | 100.00 | 7.00E-84 | 5.90E-88 | 734.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |