| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YMR080C | NAM7 | SGDID:S000004685 | IGHMBP2 SMBP2 SMUBP2 |
DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) |
3.6.4.13 | Homo sapiens | Spinal Muscular Atrophy With Lower Extremity Predominance,Adult Respiratory Distress Syndrome,Myopathy,Progressive Multifocal Leukoencephalopathy,Neuromuscular Disease,Amyotrophic Lateral Sclerosis 1,Neuronopathy, Distal Hereditary Motor, Type Iib,Spinal Muscular Atrophy,Charcot-Marie-Tooth Disease Type 2a2a,Muscular Atrophy,Anterior Horn Cell Disease,Autosomal Recessive Distal Hereditary Motor Neuronopathy,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Distal Hereditary Motor Neuronopathy Type 2,Motor Peripheral Neuropathy,Charcot-Marie-Tooth Hereditary Neuropathy,Diaphragmatic Eventration,Neuropathy,Charcot-Marie-Tooth Disease,Amyotrophic Lateral Sclerosis 4, Juvenile,Polyneuropathy,Neonatal Myasthenia Gravis,Autosomal Dominant Intermediate Charcot-Marie-Tooth,Tooth Disease,Respiratory Failure,Spinal Muscular Atrophy, Distal, Autosomal Recessive, 1,Scapuloperoneal Spinal Muscular Atrophy,Brown-Vialetto-Van Laere Syndrome,Spinal Muscular Atrophy, X-Linked 2,Neuropathy, Hereditary Sensory And Autonomic, Type Iia,Childhood Spinal Muscular Atrophy,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Ptosis,Spinal Muscular Atrophy, Type I,Spinal Muscular Atrophy, Type Iii,Spinal Muscular Atrophy, Type Ii,Charcot-Marie-Tooth Disease, Axonal, Type 2t,Neuronopathy, Distal Hereditary Motor, Type Va |
4b3f_x | P38935 | ENSG00000132740 | IGHMBP2 | 100.00 | 1.90E-43 | 2.40E-47 | 376.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YMR080C | NAM7 | SGDID:S000004685 | UPF1_Zn_bind |
RNA helicase (UPF2 interacting domain) |
pfam Domain | PF09416 | 100.00 | 1.40E-41 | 1.30E-45 | 323.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| YMR080C | NAM7 | SGDID:S000004685 | UPF1 KIAA0221 RENT1 |
Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) |
3.6.4.- | Homo sapiens | Spinal Muscular Atrophy,Autosomal Recessive Distal Hereditary Motor Neuronopathy,Long Qt Syndrome,Waardenburg Syndrome, Type 4b,Pancreatic Adenosquamous Carcinoma,Amyotrophic Lateral Sclerosis 4, Juvenile,Waardenburg Syndrome, Type 4a,Epidermolysis Bullosa, Junctional, Non-Herlitz Type,Disease Of Mental Health,Spinal Muscular Atrophy, Distal, Autosomal Recessive, 1,Coffin-Siris Syndrome 1,Choroideremia,Atrial Septal Defect 2,Ullrich Congenital Muscular Dystrophy 1 |
2xzo_a | Q92900 | ENSG00000005007 | UPF1 | 100.00 | 5.00E-61 | 6.40E-65 | 508.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YMR080C | NAM7 | SGDID:S000004685 | NAM7 IFS2 MOF4 UPF1 YMR080C YM9582.05C |
ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1) |
3.6.4.- | Saccharomyces cerevisiae | 2xzl_a | P30771 | 100.00 | 2.00E-147 | 3.00E-151 | 1245.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |