Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YNL088W | TOP2 | SGDID:S000005032 | parC SAS1295 |
DNA topoisomerase 4 subunit A (EC 5.6.2.2) (Topoisomerase IV subunit A) |
5.6.2.2 | Staphylococcus aureus | 2inr_a | Q6G9K4 | 100.00 | 3.20E-90 | 2.40E-94 | 847.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | gyrA hisW nalA parD b2231 JW2225 |
DNA gyrase subunit A (EC 5.6.2.2) |
5.6.2.2 | Escherichia coli | 1ab4_a | P0AES4 | 100.00 | 1.30E-96 | 1.00E-100 | 898.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YNL088W | TOP2 | SGDID:S000005032 | gyrA Rv0006 MTCY10H4.04 |
DNA gyrase subunit A (EC 5.6.2.2) (Type IIA topoisomerase subunit GyrA) |
5.6.2.2 | Mycobacterium tuberculosis | 3ilw_a | P9WG47 | 100.00 | 1.60E-86 | 1.30E-90 | 810.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | parC KPR_4469 |
parC KPR_4469 |
5.6.2.2 | Klebsiella pneumoniae | 5eix_a | R4YE07 | 100.00 | 3.00E-135 | 3.00E-139 | 1292.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | TOP2A TOP2 |
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) |
5.6.2.2 | Homo sapiens | Childhood Acute Lymphocytic Leukemia,Frontal Lobe Neoplasm,Spinocerebellar Ataxia Type 1 With Axonal Neuropathy,Neuroblastoma,Adenocarcinoma In Situ,Leukemia, Acute Lymphoblastic,Bladder Cancer,Ovarian Cancer,Breast Cancer,Colorectal Cancer,T-Cell Receptor-Alpha/Beta Deficiency,Malignant Peripheral Nerve Sheath Tumor,Gastric Cancer,Prostate Cancer,Cervix Endometriosis,Retinoblastoma,Myelodysplastic Syndrome,Female Breast Cancer,Wilms Tumor 1,Meningioma, Familial,Spinocerebellar Ataxia, Autosomal Recessive 23,Ataxia-Telangiectasia,Lung Cancer |
4fm9_a | P11388 | ENSG00000131747 | TOP2A | 100.00 | 1.00E-155 | 7.00E-160 | 1488.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL088W | TOP2 | SGDID:S000005032 | gyrA spr1099 |
DNA gyrase subunit A (EC 5.6.2.2) |
5.6.2.2 | Streptococcus pneumoniae | 4z2c_b | Q8DPM2 | 100.00 | 2.80E-90 | 2.10E-94 | 847.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | TOP2 TOR3 YNL088W N2244 |
DNA topoisomerase 2 (EC 5.6.2.2) (DNA topoisomerase II) |
5.6.2.2 | Saccharomyces cerevisiae | 3l4j_a | P06786 | 100.00 | 1.00E-154 | 8.00E-159 | 1479.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | TopoII |
TopoII |
5.6.2.2 | Plasmodium falciparum | 6ca8_a | Q7Z2D0 | 100.00 | 1.00E-149 | 1.00E-153 | 1435.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | gyrA ECs_3114 |
gyrA ECs_3114 |
Escherichia coli | 4ckk_a | A0A0H3JH39 | 100.00 | 9.00E-86 | 7.00E-90 | 809.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | ||||
YNL088W | TOP2 | SGDID:S000005032 | TOP2B |
DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) |
5.6.2.2 | Homo sapiens | B-Cell Immunodeficiency-Limb Anomaly-Urogenital Malformation Syndrome,Autism Spectrum Disorder,Autism |
3qx3_b | Q02880 | ENSG00000077097 | TOP2B | 100.00 | 4.00E-155 | 3.00E-159 | 1482.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL088W | TOP2 | SGDID:S000005032 | parC SP_0855 |
DNA topoisomerase 4 subunit A (EC 5.6.2.2) (Topoisomerase IV subunit A) |
5.6.2.2 | Streptococcus pneumoniae | 3rae_b | P72525 | 100.00 | 7.80E-90 | 6.00E-94 | 844.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | gyrA SA0006 |
DNA gyrase subunit A (EC 5.6.2.2) |
5.6.2.2 | Staphylococcus aureus | 5cdm_a | Q99XG5 | 100.00 | 3.80E-88 | 3.00E-92 | 827.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | parC b3019 JW2987 |
DNA topoisomerase 4 subunit A (EC 5.6.2.2) (Topoisomerase IV subunit A) |
5.6.2.2 | Escherichia coli | 1zvu_a | P0AFI2 | 100.00 | 5.60E-82 | 4.40E-86 | 810.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YNL088W | TOP2 | SGDID:S000005032 | parC PP_4912 |
parC PP_4912 |
5.6.2.2 | Pseudomonas putida | 6bq9_a | Q88DB5 | 100.00 | 2.50E-88 | 1.90E-92 | 831.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL088W | TOP2 | SGDID:S000005032 | parC ABSDF0217 |
parC ABSDF0217 |
5.6.2.2 | Acinetobacter baumannii | 2xkj_e | B0VP98 | 100.00 | 5.00E-137 | 4.00E-141 | 1313.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |