YNL104C LEU4 / SGDID:S000005048
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YNL104C LEU4 SGDID:S000005048
pyc RHE_CH04002
pyc RHE_CH04002
 6.4.1.1 Rhizobium etli
2qf7_b Q2K340 99.90 3.10E-30 2.20E-34 301.70 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
Tcur_0536
Tcur_0536
 4.1.3.39,4.1.3.43, Thermomonospora curvata
4lrs_a D1A3K8 100.00 4.80E-37 3.40E-41 313.50 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
leuA NMB1070
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase)
 2.3.3.13 Neisseria meningitidis
3rmj_b Q9JZG1 100.00 1.60E-52 1.10E-56 432.40 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
leuA Rv3710 MTV025.058
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase)
 2.3.3.13 Mycobacterium tuberculosis
3hpx_b P9WQB3 100.00 5.00E-57 3.50E-61 469.50 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
leuA2 LEPBI_I1108
leuA2 LEPBI_I1108
 2.3.3.13 Leptospira biflexa
4ov4_a B0SN40 100.00 1.50E-54 1.10E-58 452.80 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
BMEI1926
BMEI1926
 4.1.3.4 Brucella melitensis
1ydn_a Q8YEF2 100.00 6.80E-36 4.90E-40 298.90 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
dmpG
4-hydroxy-2-oxovalerate aldolase (HOA) (EC 4.1.3.39) (4-hydroxy-2-keto-pentanoic acid aldolase) (4-hydroxy-2-oxopentanoate aldolase)
 4.1.3.39 Pseudomonas sp.
1nvm_a P51016 100.00 7.10E-36 5.10E-40 305.40 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
pycA SAV1114
Pyruvate carboxylase (EC 6.4.1.1)
 6.4.1.1 Staphylococcus aureus
3hb9_a A0A0H3JRU9 99.90 9.60E-33 6.80E-37 322.00 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
leuA LMOf2365_2010
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase)
 2.3.3.13 Listeria monocytogenes
3ewb_x Q71Y35 100.00 1.90E-38 1.40E-42 317.10 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
PC
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
 6.4.1.1 Homo sapiens
Urea Cycle Disorder,Multiple Carboxylase Deficiency,Malignant Astrocytoma,Acute Porphyria,Methylmalonic Acidemia,Fructose-1,6-Bisphosphatase Deficiency,Body Mass Index Quantitative Trait Locus 11,Glutaric Acidemia I,Glycogen Storage Disease Ia,Lactic Acidosis,Nystagmus 6, Congenital, X-Linked,Propionic Acidemia,Primary Cutaneous Amyloidosis,Hyperinsulinemic Hypoglycemia, Familial, 6,Biotin Deficiency,Mitochondrial Complex Ii Deficiency, Nuclear Type 1,Biotinidase Deficiency,Holocarboxylase Synthetase Deficiency,Pyruvate Dehydrogenase E1-Alpha Deficiency,Pyruvate Carboxylase Deficiency
 3bg3_a P11498 ENSG00000173599 PC 100.00 1.30E-34 8.80E-39 319.50 1 1 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
oadA-2 ERS013165_02612
oadA-2 ERS013165_02612
 2.1.3.1,4.1.1.3, Vibrio cholerae
2nx9_a Q6A1F6 100.00 3.10E-36 2.10E-40 316.80 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
yngG BSU18230
Hydroxymethylglutaryl-CoA lyase YngG (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)
 4.1.3.4 Bacillus subtilis
1ydo_c O34873 99.90 8.10E-34 5.80E-38 285.30 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
lys4 SPBC1105.02c
Homocitrate synthase, mitochondrial (HCS) (EC 2.3.3.14)
 2.3.3.14 Schizosaccharomyces pombe
3ivs_b Q9Y823 100.00 2.30E-52 1.60E-56 437.00 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
Mfla_1512
Mfla_1512
 Methylobacillus flagellatus
5ks8_c Q1H157 100.00 1.60E-35 1.10E-39 323.90 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
gsl-elong-A1
gsl-elong-A1
 Brassica juncea
6e1j_a C5J4P1 100.00 5.00E-57 3.50E-61 477.20 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
liuE PA2011
3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase (HIHG-CoA lyase) (HMG-CoA lyase) (EC 4.1.3.26) (EC 4.1.3.4) ((S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase) (3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase)
 4.1.3.26,4.1.3.4, Pseudomonas aeruginosa
2ftp_a Q9I2A0 100.00 1.40E-36 1.00E-40 303.60 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
hsaF Rv3534c
4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) (4-hydroxy-2-keto-pentanoic acid aldolase) (4-hydroxy-2-oxopentanoate aldolase) (4-hydroxy-2-oxovalerate aldolase) (HOA) (EC 4.1.3.39)
 4.1.3.39,4.1.3.43, Mycobacterium tuberculosis
4jn6_a P9WMK5 100.00 2.00E-36 1.40E-40 309.90 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
BVU_2661
BVU_2661
 Bacteroides vulgatus
3dxi_a A6L3P9 100.00 1.70E-34 1.20E-38 290.20 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
cimA LA_2350
(R)-citramalate synthase CimA (EC 2.3.1.182) (LiCMS)
 2.3.1.182 Leptospira interrogans
3ble_a Q8F3Q1 100.00 2.80E-43 2.00E-47 358.90 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)
 4.1.3.4 Homo sapiens
Retinitis Pigmentosa,Hypoglycemia,Uniparental Disomy Of Chromosome 1,Reye Syndrome,Methylmalonic Acidemia,Propionic Acidemia,Autosomal Recessive Disease,Metabolic Acidosis,3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency,Fumarase Deficiency,Maple Syrup Urine Disease,Organic Acidemia,Alpha-Methylacetoacetic Aciduria,Left Ventricular Noncompaction
 2cw6_c P35914 ENSG00000117305 HMGCL 99.90 8.70E-33 6.20E-37 276.30 1 1 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
5S
Methylmalonyl-CoA carboxyltransferase 5S subunit (EC 2.1.3.1) (Transcarboxylase 5S subunit)
 2.1.3.1 Propionibacterium freudenreichii
1rqb_a Q70AC7 100.00 7.50E-36 5.30E-40 319.20 0 0 0 0 0 0 0 0
YNL104C LEU4 SGDID:S000005048
lys20 TT_C1550
Homocitrate synthase (HCS) (EC 2.3.3.14)
 2.3.3.14 Thermus thermophilus
2ztj_a O87198 100.00 4.40E-54 3.10E-58 445.60 0 0 0 0 0 0 0 0