| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YNL123W | NMA111 | SGDID:S000005067 | htrA lpg1331 |
htrA lpg1331 |
3.4.21.107 | Legionella pneumophila | 4ynn_c | Q5ZVV9 | 99.90 | 1.70E-27 | 1.10E-31 | 268.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | HTRA3 PRSP |
Serine protease HTRA3 (EC 3.4.21.-) (High-temperature requirement factor A3) (Pregnancy-related serine protease) |
3.4.21.- | Homo sapiens | 4ri0_a | P83110 | ENSG00000170801 | HTRA3 | 99.60 | 6.70E-21 | 4.50E-25 | 205.00 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YNL123W | NMA111 | SGDID:S000005067 | Rv3671c |
Serine protease Rv3671c (EC 3.4.21.-) |
3.4.21.- | Mycobacterium tuberculosis | 3k6y_a | P9WHR9 | 98.80 | 1.90E-12 | 1.30E-16 | 130.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | splA SAOUHSC_01942 |
Serine protease SplA (EC 3.4.21.-) |
3.4.21.- | Staphylococcus aureus | 4mvn_d | Q2FXC2 | 98.40 | 1.60E-10 | 1.00E-14 | 112.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | splB SAOUHSC_01941 |
Serine protease SplB (EC 3.4.21.-) |
3.4.21.- | Staphylococcus aureus | 4k1t_b | Q2FXC3 | 98.40 | 1.50E-10 | 1.00E-14 | 113.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | splC SAOUHSC_01939 |
Serine protease SplC (EC 3.4.21.-) |
3.4.21.- | Staphylococcus aureus | 2as9_a | Q2FXC4 | 98.20 | 6.30E-10 | 4.20E-14 | 109.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | splD SAOUHSC_01938 |
Serine protease SplD (EC 3.4.21.-) |
3.4.21.- | Staphylococcus aureus | 4ink_a | Q2FXC5 | 98.30 | 2.80E-10 | 1.90E-14 | 111.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | splE SAOUHSC_01936 |
Serine protease SplE (EC 3.4.21.-) |
3.4.21.- | Staphylococcus aureus | 5mm8_a | Q2FXC7 | 98.20 | 4.70E-10 | 3.10E-14 | 109.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | mamO amb0969 |
Probable membrane transporter protein MamO |
Magnetospirillum magneticum | 5hm9_a | Q2W8Q2 | 98.80 | 9.20E-13 | 6.10E-17 | 127.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | Protein p19 (Serine protease p27) (Transmembrane protein 1A) |
Protein p19 (Serine protease p27) (Transmembrane protein 1A) |
Human astrovirus | 2w5e_c | Q3ZN04 | 98.20 | 5.20E-10 | 3.40E-14 | 104.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | hhoA sll1679 |
Putative serine protease HhoA |
Synechocystis sp. | 5b6l_a | P72780 | 99.70 | 3.80E-22 | 2.50E-26 | 216.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | LYSC |
Lysyl endopeptidase (EC 3.4.21.50) (Lys-C) |
3.4.21.50 | Lysobacter enzymogenes | 4nsv_a | Q7M135 | 98.30 | 2.50E-10 | 1.60E-14 | 117.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | HTRA1 HTRA PRSS11 |
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11) |
3.4.21.- | Homo sapiens | Lattice Corneal Dystrophy,Choroiditis,Roberts-Sc Phocomelia Syndrome,Cerebrovascular Disease,Multifocal Choroiditis,Degeneration Of Macula And Posterior Pole,Ophthalmia Neonatorum,Pattern Dystrophy,Spondylosis,Col4a1-Related Familial Vascular Leukoencephalopathy,Alopecia,Pseudobulbar Palsy,Htra1-Related Cerebral Small Vessel Disease,Corneal Dystrophy,Retinal Degeneration,Htra1 Disorder,Tick-Borne Relapsing Fever,Dementia,Fundus Dystrophy,Endocarditis,Pneumonic Plague,Eye Disease,Campylobacteriosis,Post-Vaccinal Encephalitis,Inclusion Conjunctivitis,Kuhnt-Junius Degeneration,Malignant Peripheral Nerve Sheath Tumor,Macular Degeneration, Age-Related, 1,Bartonellosis,Spotted Fever,Cat-Scratch Disease,Ornithosis,Chlamydia,Macular Degeneration, Age-Related, 7,Cerebral Arteriopathy, Autosomal Dominant, With Subcortical Infarcts And Leukoencephalopathy, Type 1,Rheumatoid Arthritis,Japanese Spotted Fever,Rocky Mountain Spotted Fever,Epidemic Typhus,Endemic Typhus,Late-Onset Retinal Degeneration,Cardiomyopathy, Dilated, 1l,Vasculopathy, Retinal, With Cerebral Leukoencephalopathy And Systemic Manifestations,Cerebral Arteriopathy, Autosomal Dominant, With Subcortical Infarcts And Leukoencephalopathy, Type 2,Osteopetrosis, Autosomal Dominant 1,Bacillary Angiomatosis,Cerebral Arteriopathy, Autosomal Recessive, With Subcortical Infarcts And Leukoencephalopathy |
3num_a | Q92743 | ENSG00000166033 | HTRA1 | 99.60 | 3.50E-20 | 2.30E-24 | 199.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL123W | NMA111 | SGDID:S000005067 | sspA SAV1048 |
Glutamyl endopeptidase (EC 3.4.21.19) (Endoproteinase Glu-C) (Staphylococcal serine proteinase) (V8 protease) (V8 proteinase) |
3.4.21.19 | Staphylococcus aureus | 2o8l_a | Q99V45 | 98.40 | 1.00E-10 | 6.90E-15 | 120.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | N-terminal protein (Serine protease) (VPg) |
N-terminal protein (Serine protease) (VPg) |
Sesbania mosaic | 1zyo_a | Q9EB08 | 98.30 | 3.10E-10 | 2.10E-14 | 109.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | DEGP9 At5g40200 MSN9.10 MSN9.100 |
Protease Do-like 9 (EC 3.4.21.-) |
3.4.21.- | Arabidopsis thaliana | 5il9_a | Q9FL12 | 99.90 | 1.30E-29 | 8.70E-34 | 293.50 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | DEGP8 At5g39830 K13H13.1 |
Protease Do-like 8, chloroplastic (EC 3.4.21.-) |
3.4.21.- | Arabidopsis thaliana | 4ic6_a | Q9LU10 | 99.60 | 2.30E-20 | 1.50E-24 | 203.80 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | DEGP5 HHOA At4g18370 F28J12.30 |
Protease Do-like 5, chloroplastic (EC 3.4.21.-) |
3.4.21.- | Arabidopsis thaliana | 4ic5_a | Q9SEL7 | 98.90 | 1.90E-13 | 1.20E-17 | 142.80 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | TM_0571 |
TM_0571 |
Thermotoga maritima | 1l1j_a | Q9WZ41 | 99.10 | 3.00E-14 | 2.00E-18 | 144.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | POLG |
Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component proteinase (HC-pro) (EC 3.4.22.45); Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein (CI) (EC 3.6.4.-); 6 kDa protein 2 (6K2); Viral genome-linked protein (VPg); Nuclear inclusion protein A (NI-a) (NIa) (EC 3.4.22.44) (49 kDa proteinase) (49 kDa-Pro) (NIa-pro); Nuclear inclusion protein B (NI-b) (NIb) (EC 2.7.7.48) (RNA-directed RNA polymerase); Capsid protein (CP) (Coat protein)] |
2.7.7.48,3.4.22.44,3.4.22.45 | Tobacco etch | 1lvm_a | P04517 | 98.20 | 9.00E-10 | 6.00E-14 | 109.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | Mmc1_2254 |
Mmc1_2254 |
Magnetococcus marinus | 4jj0_b | A0L9W2 | 98.30 | 2.10E-10 | 1.40E-14 | 113.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | RNA-directed RNA polymerase (EC 2.7.7.48) |
RNA-directed RNA polymerase (EC 2.7.7.48) |
Ryegrass mottle | 6ff0_a | A0MCW0 | 98.30 | 2.70E-10 | 1.80E-14 | 116.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL123W | NMA111 | SGDID:S000005067 | Periplasmic serine endoprotease DegP-like (EC 3.4.21.107) |
Periplasmic serine endoprotease DegP-like (EC 3.4.21.107) |
3.4.21.107 | Legionella fallonii | 3pv2_c | F8W672 | 99.90 | 8.10E-30 | 5.30E-34 | 288.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | hp1018/19 |
hp1018/19 |
3.4.21.107 | Helicobacter pylori | 5y28_c | G2J5T2 | 99.70 | 3.40E-21 | 2.20E-25 | 209.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | htrA1 degP htrA Rv1223 |
Probable serine protease HtrA1 (EC 3.4.21.107) (High-temperature requirement A protease) |
3.4.21.107 | Mycobacterium tuberculosis | 6ieo_a | O06291 | 99.60 | 8.50E-21 | 5.70E-25 | 202.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | DEGP1 DEG1 DEGP At3g27925 K16N12.18 |
Protease Do-like 1, chloroplastic (EC 3.4.21.-) (Protein DEGRADATION OF PERIPLASMIC PROTEINS 1) (DEGP PROTEASE 1) |
3.4.21.- | Arabidopsis thaliana | 3qo6_a | O22609 | 99.60 | 7.80E-21 | 5.20E-25 | 205.90 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | HTRA2 OMI PRSS25 |
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI) |
3.4.21.108 | Homo sapiens | Amyotrophic Lateral Sclerosis 1,3-Methylglutaconic Aciduria, Type Viii,Essential Tremor,Tremor, Hereditary Essential, 2,Parkinson Disease, Late-Onset,Parkinson Disease 3, Autosomal Dominant,Parkinson Disease 13, Autosomal Dominant,Tremor, Hereditary Essential, 3,Tremor, Hereditary Essential, 1,Mitochondrial Complex I Deficiency, Nuclear Type 1,3-Methylglutaconic Aciduria,Parkinson Disease 2, Autosomal Recessive Juvenile,3-Methylglutaconic Aciduria, Type Iii |
1lcy_a | O43464 | ENSG00000115317 | HTRA2 | 99.70 | 3.80E-21 | 2.50E-25 | 206.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL123W | NMA111 | SGDID:S000005067 | pepD htrA2 Rv0983 |
Serine protease PepD (EC 3.4.21.107) (HtrA-like serine protease) |
3.4.21.107 | Mycobacterium tuberculosis | 1y8t_b | O53896 | 99.60 | 1.10E-20 | 7.60E-25 | 202.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | DEGP2 At2g47940 F17A22.33 T9J23.7 |
Protease Do-like 2, chloroplastic (EC 3.4.21.-) |
3.4.21.- | Arabidopsis thaliana | 4fln_b | O82261 | 99.90 | 1.10E-30 | 7.30E-35 | 300.90 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | AZU1 |
Azurocidin (Cationic antimicrobial protein CAP37) (Heparin-binding protein) (HBP) (hHBP) |
Homo sapiens | Subdural Empyema,Cornea Cancer,Hepatic Veno-Occlusive Disease,Acute Inflammation Of Lacrimal Passage,Dacryocystitis,Acute Proliferative Glomerulonephritis,Erysipelas,Coxa Vara,Thrombocytopenia,Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome |
1a7s_a | P20160 | 98.60 | 1.60E-11 | 1.10E-15 | 122.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | etb |
Exfoliative toxin B (EC 3.4.21.-) (Epidermolytic toxin B) |
3.4.21.- | Staphylococcus aureus | 1dt2_a | P09332 | 98.20 | 8.10E-10 | 5.40E-14 | 111.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | POLG |
Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component proteinase (HC-pro) (EC 3.4.22.45); Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein (CI) (EC 3.6.4.-); 6 kDa protein 2 (6K2); Viral genome-linked protein (VPg); Nuclear inclusion protein A (NI-a) (NIa) (EC 3.4.22.44) (49 kDa proteinase) (49 kDa-Pro) (NIa-pro); Nuclear inclusion protein B (NI-b) (NIb) (EC 2.7.7.48) (RNA-directed RNA polymerase); Capsid protein (CP) (Coat protein)] |
2.7.7.48,3.4.22.44,3.4.22.45 | Tobacco vein | 3mmg_a | P09814 | 98.30 | 3.30E-10 | 2.20E-14 | 113.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | degS hhoB htrH b3235 JW3204 |
Serine endoprotease DegS (EC 3.4.21.107) (Site-1 protease DegS) (S1P protease DegS) (Site-1-type intramembrane protease) |
3.4.21.107 | Escherichia coli | 1te0_b | P0AEE3 | 99.70 | 4.90E-21 | 3.30E-25 | 204.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YNL123W | NMA111 | SGDID:S000005067 | gseA esp SE_1543 |
Glutamyl endopeptidase (EC 3.4.21.19) (Glutamic acid-specific protease) (GluSE) |
3.4.21.19 | Staphylococcus epidermidis | 4jcn_a | P0C0Q2 | 98.40 | 1.20E-10 | 8.20E-15 | 114.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | degP htrA ptd b0161 JW0157 |
Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do) |
3.4.21.107 | Escherichia coli | 1ky9_b | P0C0V0 | 99.90 | 2.10E-30 | 1.40E-34 | 292.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YNL123W | NMA111 | SGDID:S000005067 | sspA |
Glutamyl endopeptidase (EC 3.4.21.19) (Endoproteinase Glu-C) (Staphylococcal serine proteinase) (V8 protease) (V8 proteinase) |
3.4.21.19 | Staphylococcus aureus | 1wcz_a | P0C1U8 | 98.50 | 5.20E-11 | 3.50E-15 | 122.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | API |
Protease 1 (EC 3.4.21.50) (API) (Lysyl endopeptidase) (Protease I) |
3.4.21.50 | Achromobacter lyticus | 1arc_a | P15636 | 98.40 | 9.20E-11 | 6.10E-15 | 120.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL123W | NMA111 | SGDID:S000005067 | degQ hhoA b3234 JW3203 |
Periplasmic pH-dependent serine endoprotease DegQ (EC 3.4.21.107) (Protease Do) |
3.4.21.107 | Escherichia coli | 3stj_b | P39099 | 99.70 | 8.30E-22 | 5.50E-26 | 213.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |