YNL123W NMA111 / SGDID:S000005067
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YNL123W NMA111 SGDID:S000005067
pepD htrA2 Rv0983
Serine protease PepD (EC 3.4.21.107) (HtrA-like serine protease)
 3.4.21.107 Mycobacterium tuberculosis
1y8t_b O53896 99.60 1.10E-20 7.60E-25 202.70 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
splC SAOUHSC_01939
Serine protease SplC (EC 3.4.21.-)
 3.4.21.- Staphylococcus aureus
2as9_a Q2FXC4 98.20 6.30E-10 4.20E-14 109.10 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
degP htrA ptd b0161 JW0157
Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do)
 3.4.21.107 Escherichia coli
1ky9_b P0C0V0 99.90 2.10E-30 1.40E-34 292.50 0 0 0 0 0 0 0 1
YNL123W NMA111 SGDID:S000005067
HTRA1 HTRA PRSS11
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)
 3.4.21.- Homo sapiens
Lattice Corneal Dystrophy,Choroiditis,Roberts-Sc Phocomelia Syndrome,Cerebrovascular Disease,Multifocal Choroiditis,Degeneration Of Macula And Posterior Pole,Ophthalmia Neonatorum,Pattern Dystrophy,Spondylosis,Col4a1-Related Familial Vascular Leukoencephalopathy,Alopecia,Pseudobulbar Palsy,Htra1-Related Cerebral Small Vessel Disease,Corneal Dystrophy,Retinal Degeneration,Htra1 Disorder,Tick-Borne Relapsing Fever,Dementia,Fundus Dystrophy,Endocarditis,Pneumonic Plague,Eye Disease,Campylobacteriosis,Post-Vaccinal Encephalitis,Inclusion Conjunctivitis,Kuhnt-Junius Degeneration,Malignant Peripheral Nerve Sheath Tumor,Macular Degeneration, Age-Related, 1,Bartonellosis,Spotted Fever,Cat-Scratch Disease,Ornithosis,Chlamydia,Macular Degeneration, Age-Related, 7,Cerebral Arteriopathy, Autosomal Dominant, With Subcortical Infarcts And Leukoencephalopathy, Type 1,Rheumatoid Arthritis,Japanese Spotted Fever,Rocky Mountain Spotted Fever,Epidemic Typhus,Endemic Typhus,Late-Onset Retinal Degeneration,Cardiomyopathy, Dilated, 1l,Vasculopathy, Retinal, With Cerebral Leukoencephalopathy And Systemic Manifestations,Cerebral Arteriopathy, Autosomal Dominant, With Subcortical Infarcts And Leukoencephalopathy, Type 2,Osteopetrosis, Autosomal Dominant 1,Bacillary Angiomatosis,Cerebral Arteriopathy, Autosomal Recessive, With Subcortical Infarcts And Leukoencephalopathy
 3num_a Q92743 ENSG00000166033 HTRA1 99.60 3.50E-20 2.30E-24 199.20 1 1 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
DEGP1 DEG1 DEGP At3g27925 K16N12.18
Protease Do-like 1, chloroplastic (EC 3.4.21.-) (Protein DEGRADATION OF PERIPLASMIC PROTEINS 1) (DEGP PROTEASE 1)
 3.4.21.- Arabidopsis thaliana
3qo6_a O22609 99.60 7.80E-21 5.20E-25 205.90 0 0 0 0 0 0 1 0
YNL123W NMA111 SGDID:S000005067
splA SAOUHSC_01942
Serine protease SplA (EC 3.4.21.-)
 3.4.21.- Staphylococcus aureus
4mvn_d Q2FXC2 98.40 1.60E-10 1.00E-14 112.30 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
degS hhoB htrH b3235 JW3204
Serine endoprotease DegS (EC 3.4.21.107) (Site-1 protease DegS) (S1P protease DegS) (Site-1-type intramembrane protease)
 3.4.21.107 Escherichia coli
1te0_b P0AEE3 99.70 4.90E-21 3.30E-25 204.90 0 0 0 0 0 0 0 1
YNL123W NMA111 SGDID:S000005067
htrA lpg1331
htrA lpg1331
 3.4.21.107 Legionella pneumophila
4ynn_c Q5ZVV9 99.90 1.70E-27 1.10E-31 268.50 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
hp1018/19
hp1018/19
 3.4.21.107 Helicobacter pylori
5y28_c G2J5T2 99.70 3.40E-21 2.20E-25 209.20 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
HTRA3 PRSP
Serine protease HTRA3 (EC 3.4.21.-) (High-temperature requirement factor A3) (Pregnancy-related serine protease)
 3.4.21.- Homo sapiens
4ri0_a P83110 ENSG00000170801 HTRA3 99.60 6.70E-21 4.50E-25 205.00 0 1 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
DEGP5 HHOA At4g18370 F28J12.30
Protease Do-like 5, chloroplastic (EC 3.4.21.-)
 3.4.21.- Arabidopsis thaliana
4ic5_a Q9SEL7 98.90 1.90E-13 1.20E-17 142.80 0 0 0 0 0 0 1 0
YNL123W NMA111 SGDID:S000005067
etb
Exfoliative toxin B (EC 3.4.21.-) (Epidermolytic toxin B)
 3.4.21.- Staphylococcus aureus
1dt2_a P09332 98.20 8.10E-10 5.40E-14 111.40 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
mamO amb0969
Probable membrane transporter protein MamO
 Magnetospirillum magneticum
5hm9_a Q2W8Q2 98.80 9.20E-13 6.10E-17 127.30 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
RNA-directed RNA polymerase (EC 2.7.7.48)
RNA-directed RNA polymerase (EC 2.7.7.48)
 Ryegrass mottle
6ff0_a A0MCW0 98.30 2.70E-10 1.80E-14 116.80 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
degQ hhoA b3234 JW3203
Periplasmic pH-dependent serine endoprotease DegQ (EC 3.4.21.107) (Protease Do)
 3.4.21.107 Escherichia coli
3stj_b P39099 99.70 8.30E-22 5.50E-26 213.20 0 0 0 0 0 0 0 1
YNL123W NMA111 SGDID:S000005067
DEGP9 At5g40200 MSN9.10 MSN9.100
Protease Do-like 9 (EC 3.4.21.-)
 3.4.21.- Arabidopsis thaliana
5il9_a Q9FL12 99.90 1.30E-29 8.70E-34 293.50 0 0 0 0 0 0 1 0
YNL123W NMA111 SGDID:S000005067
DEGP2 At2g47940 F17A22.33 T9J23.7
Protease Do-like 2, chloroplastic (EC 3.4.21.-)
 3.4.21.- Arabidopsis thaliana
4fln_b O82261 99.90 1.10E-30 7.30E-35 300.90 0 0 0 0 0 0 1 0
YNL123W NMA111 SGDID:S000005067
splD SAOUHSC_01938
Serine protease SplD (EC 3.4.21.-)
 3.4.21.- Staphylococcus aureus
4ink_a Q2FXC5 98.30 2.80E-10 1.90E-14 111.10 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
AZU1
Azurocidin (Cationic antimicrobial protein CAP37) (Heparin-binding protein) (HBP) (hHBP)
 Homo sapiens
Subdural Empyema,Cornea Cancer,Hepatic Veno-Occlusive Disease,Acute Inflammation Of Lacrimal Passage,Dacryocystitis,Acute Proliferative Glomerulonephritis,Erysipelas,Coxa Vara,Thrombocytopenia,Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome
 1a7s_a P20160 98.60 1.60E-11 1.10E-15 122.20 1 1 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
sspA
Glutamyl endopeptidase (EC 3.4.21.19) (Endoproteinase Glu-C) (Staphylococcal serine proteinase) (V8 protease) (V8 proteinase)
 3.4.21.19 Staphylococcus aureus
1wcz_a P0C1U8 98.50 5.20E-11 3.50E-15 122.30 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
sspA SAV1048
Glutamyl endopeptidase (EC 3.4.21.19) (Endoproteinase Glu-C) (Staphylococcal serine proteinase) (V8 protease) (V8 proteinase)
 3.4.21.19 Staphylococcus aureus
2o8l_a Q99V45 98.40 1.00E-10 6.90E-15 120.40 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
HTRA2 OMI PRSS25
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)
 3.4.21.108 Homo sapiens
Amyotrophic Lateral Sclerosis 1,3-Methylglutaconic Aciduria, Type Viii,Essential Tremor,Tremor, Hereditary Essential, 2,Parkinson Disease, Late-Onset,Parkinson Disease 3, Autosomal Dominant,Parkinson Disease 13, Autosomal Dominant,Tremor, Hereditary Essential, 3,Tremor, Hereditary Essential, 1,Mitochondrial Complex I Deficiency, Nuclear Type 1,3-Methylglutaconic Aciduria,Parkinson Disease 2, Autosomal Recessive Juvenile,3-Methylglutaconic Aciduria, Type Iii
 1lcy_a O43464 ENSG00000115317 HTRA2 99.70 3.80E-21 2.50E-25 206.30 1 1 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
splB SAOUHSC_01941
Serine protease SplB (EC 3.4.21.-)
 3.4.21.- Staphylococcus aureus
4k1t_b Q2FXC3 98.40 1.50E-10 1.00E-14 113.20 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
gseA esp SE_1543
Glutamyl endopeptidase (EC 3.4.21.19) (Glutamic acid-specific protease) (GluSE)
 3.4.21.19 Staphylococcus epidermidis
4jcn_a P0C0Q2 98.40 1.20E-10 8.20E-15 114.80 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
LYSC
Lysyl endopeptidase (EC 3.4.21.50) (Lys-C)
 3.4.21.50 Lysobacter enzymogenes
4nsv_a Q7M135 98.30 2.50E-10 1.60E-14 117.20 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
htrA1 degP htrA Rv1223
Probable serine protease HtrA1 (EC 3.4.21.107) (High-temperature requirement A protease)
 3.4.21.107 Mycobacterium tuberculosis
6ieo_a O06291 99.60 8.50E-21 5.70E-25 202.70 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
Rv3671c
Serine protease Rv3671c (EC 3.4.21.-)
 3.4.21.- Mycobacterium tuberculosis
3k6y_a P9WHR9 98.80 1.90E-12 1.30E-16 130.50 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
TM_0571
TM_0571
 Thermotoga maritima
1l1j_a Q9WZ41 99.10 3.00E-14 2.00E-18 144.40 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
POLG
Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component proteinase (HC-pro) (EC 3.4.22.45); Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein (CI) (EC 3.6.4.-); 6 kDa protein 2 (6K2); Viral genome-linked protein (VPg); Nuclear inclusion protein A (NI-a) (NIa) (EC 3.4.22.44) (49 kDa proteinase) (49 kDa-Pro) (NIa-pro); Nuclear inclusion protein B (NI-b) (NIb) (EC 2.7.7.48) (RNA-directed RNA polymerase); Capsid protein (CP) (Coat protein)]
 2.7.7.48,3.4.22.44,3.4.22.45 Tobacco vein
3mmg_a P09814 98.30 3.30E-10 2.20E-14 113.90 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
Protein p19 (Serine protease p27) (Transmembrane protein 1A)
Protein p19 (Serine protease p27) (Transmembrane protein 1A)
 Human astrovirus
2w5e_c Q3ZN04 98.20 5.20E-10 3.40E-14 104.60 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
Periplasmic serine endoprotease DegP-like (EC 3.4.21.107)
Periplasmic serine endoprotease DegP-like (EC 3.4.21.107)
 3.4.21.107 Legionella fallonii
3pv2_c F8W672 99.90 8.10E-30 5.30E-34 288.20 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
hhoA sll1679
Putative serine protease HhoA
 Synechocystis sp.
5b6l_a P72780 99.70 3.80E-22 2.50E-26 216.30 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
DEGP8 At5g39830 K13H13.1
Protease Do-like 8, chloroplastic (EC 3.4.21.-)
 3.4.21.- Arabidopsis thaliana
4ic6_a Q9LU10 99.60 2.30E-20 1.50E-24 203.80 0 0 0 0 0 0 1 0
YNL123W NMA111 SGDID:S000005067
POLG
Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component proteinase (HC-pro) (EC 3.4.22.45); Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein (CI) (EC 3.6.4.-); 6 kDa protein 2 (6K2); Viral genome-linked protein (VPg); Nuclear inclusion protein A (NI-a) (NIa) (EC 3.4.22.44) (49 kDa proteinase) (49 kDa-Pro) (NIa-pro); Nuclear inclusion protein B (NI-b) (NIb) (EC 2.7.7.48) (RNA-directed RNA polymerase); Capsid protein (CP) (Coat protein)]
 2.7.7.48,3.4.22.44,3.4.22.45 Tobacco etch
1lvm_a P04517 98.20 9.00E-10 6.00E-14 109.50 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
splE SAOUHSC_01936
Serine protease SplE (EC 3.4.21.-)
 3.4.21.- Staphylococcus aureus
5mm8_a Q2FXC7 98.20 4.70E-10 3.10E-14 109.30 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
Mmc1_2254
Mmc1_2254
 Magnetococcus marinus
4jj0_b A0L9W2 98.30 2.10E-10 1.40E-14 113.40 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
API
Protease 1 (EC 3.4.21.50) (API) (Lysyl endopeptidase) (Protease I)
 3.4.21.50 Achromobacter lyticus
1arc_a P15636 98.40 9.20E-11 6.10E-15 120.30 0 0 0 0 0 0 0 0
YNL123W NMA111 SGDID:S000005067
N-terminal protein (Serine protease) (VPg)
N-terminal protein (Serine protease) (VPg)
 Sesbania mosaic
1zyo_a Q9EB08 98.30 3.10E-10 2.10E-14 109.50 0 0 0 0 0 0 0 0