Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YNL331C | AAD14 | SGDID:S000005275 | AKR1B1 ALDR1 ALR2 |
Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR) (EC 1.1.1.21) |
1.1.1.21,1.1.1.300,1.1.1.372,1.1.1.54, | Homo sapiens | Severe Nonproliferative Diabetic Retinopathy,Autonomic Nervous System Disease,Diabetic Autonomic Neuropathy,Autonomic Neuropathy,American Histoplasmosis,Hyperglycemia,Diabetic Macular Edema,Microvascular Complications Of Diabetes 5,Polyradiculopathy,Diabetes Mellitus,Transient Refractive Change,Macular Retinal Edema,Alzheimer Disease,Constipation,Punctate Epithelial Keratoconjunctivitis,Diabetic Neuropathy,Keratopathy,Retinal Vascular Disease,Sensory Peripheral Neuropathy,Diabetic Polyneuropathy,Cataract,Retinal Degeneration,Corneal Disease,Type 1 Diabetes Mellitus,Background Diabetic Retinopathy,Diabetic Cataract,Kidney Disease,Neuropathy,Mature Cataract,Peripheral Nervous System Disease,Polyneuropathy,Lens Disease,Retinal Microaneurysm,Galactosemia I,Microvascular Complications Of Diabetes 1,Body Mass Index Quantitative Trait Locus 11,Type 2 Diabetes Mellitus,Ophthalmomyiasis,Pigmentary Disorder, Reticulate, With Systemic Manifestations, X-Linked,Hypertension, Essential,Membranous Nephropathy,Asthma |
3m64_a | P15121 | ENSG00000085662 | AKR1B1 | 100.00 | 2.60E-44 | 1.70E-48 | 315.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL331C | AAD14 | SGDID:S000005275 | dkgA yqhE b3012 JW5499 |
2,5-diketo-D-gluconic acid reductase A (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (EC 1.1.1.274) (AKR5C) |
1.1.1.274 | Escherichia coli | 1mzr_b | Q46857 | 100.00 | 3.40E-40 | 2.20E-44 | 285.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YNL331C | AAD14 | SGDID:S000005275 | Akr1a1 Akr1a4 |
Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.33) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20) |
1.1.1.19,1.1.1.2,1.1.1.20,1.1.1.33,1.1.1.372,1.1.1.54, | Mus musculus | 4gac_b | Q9JII6 | 100.00 | 1.30E-42 | 8.30E-47 | 305.60 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | Akr1c9 |
3-alpha-hydroxysteroid dehydrogenase (3-alpha-HSD) (EC 1.1.1.50) (Hydroxyprostaglandin dehydrogenase) |
1.1.1.50 | Rattus norvegicus | 1afs_a | P23457 | 100.00 | 2.50E-52 | 1.60E-56 | 365.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | ydhF b1647 JW1639 |
Oxidoreductase YdhF (EC 1.-.-.-) |
Escherichia coli | 1og6_c | P76187 | 100.00 | 4.20E-48 | 2.70E-52 | 337.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | ||||
YNL331C | AAD14 | SGDID:S000005275 | YPO2805 |
YPO2805 |
1.1.1.- | Yersinia pestis | 4mhb_c | Q7CJX8 | 100.00 | 9.80E-48 | 6.30E-52 | 333.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | yeaE KPN_01195 |
yeaE KPN_01195 |
Klebsiella pneumoniae | 6cia_a | A6T7Q7 | 100.00 | 3.30E-46 | 2.10E-50 | 322.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | XYL1 XYLR |
NAD(P)H-dependent D-xylose reductase (XR) (EC 1.1.1.307) |
1.1.1.307 | Candida tenuis | 1z9a_b | O74237 | 100.00 | 8.00E-44 | 5.20E-48 | 312.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | CHR |
CHR |
Medicago sativa | 1zgd_a | Q40309 | 100.00 | 3.90E-44 | 2.50E-48 | 313.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | PGFS |
9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) |
1.1.1.- | Trypanosoma brucei | 1vbj_a | Q9GV41 | 100.00 | 3.50E-44 | 2.20E-48 | 308.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | AKR1C2 DDH2 |
Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.357) |
1.1.1.357,1.3.1.20, | Homo sapiens | Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 2,Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 1,Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 3,Parasitic Protozoa Infectious Disease,Glucosephosphate Dehydrogenase Deficiency,Colorectal Cancer, Hereditary Nonpolyposis, Type 2,Mixed Malaria,46,Xy Sex Reversal,Lynch Syndrome I,Prostate Cancer,Body Mass Index Quantitative Trait Locus 11,Pseudohermaphroditism,Bile Acid Synthesis Defect, Congenital, 2,Malaria,46,Xy Sex Reversal 8,Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia |
4l1w_b | P52895 | ENSG00000151632 | AKR1C2 | 100.00 | 1.60E-42 | 1.10E-46 | 304.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL331C | AAD14 | SGDID:S000005275 | cpr-c2 |
NADPH-dependent conjugated polyketone reductase C2 (CPR) (2-dehydropantolactone reductase) (EC 1.1.1.358) (2-dehydropantolactone reductase (A-specific)) (EC 1.1.1.168) (Ketopantoyl-lactone reductase) |
1.1.1.168,1.1.1.358, | Candida parapsilosis | 3vxg_a | Q76L36 | 100.00 | 4.70E-45 | 3.00E-49 | 321.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | gpr_2 CBEIJ_11710 |
gpr_2 CBEIJ_11710 |
Clostridium beijerinckii | 6hg6_a | A0A1S8QGT2 | 100.00 | 6.30E-47 | 4.10E-51 | 334.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | yvgN BSU33400 |
Glyoxal reductase (GR) (EC 1.1.1.-) (Methylglyoxal reductase) (EC 1.1.1.283) |
1.1.1.283 | Bacillus subtilis | 3f7j_b | O32210 | 100.00 | 6.20E-43 | 4.00E-47 | 300.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | BAB2_0177 |
BAB2_0177 |
1.1.1.- | Brucella abortus | 3o0k_a | Q2YII2 | 100.00 | 1.10E-42 | 7.20E-47 | 299.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | SMc01429 |
SMc01429 |
1.1.1.- | Rhizobium meliloti | 4pmj_a | Q92NR7 | 100.00 | 2.60E-45 | 1.70E-49 | 316.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | iolS yxbF BSU39780 SS92ER |
Aldo-keto reductase IolS (EC 1.1.1.-) (AKR11A) (Vegetative protein 147) (VEG147) |
1.1.1.- | Bacillus subtilis | 1pz0_a | P46336 | 100.00 | 1.20E-47 | 7.70E-52 | 336.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | GOX1615 |
GOX1615 |
1.1.1.- | Gluconobacter oxydans | 3n2t_a | Q5FQJ0 | 100.00 | 1.20E-47 | 8.10E-52 | 340.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | XR |
XR |
Debaryomyces nepalensis | 5zcm_a | A0A0M4HL56 | 100.00 | 9.10E-43 | 5.90E-47 | 307.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | Aldo_ket_red domain-containing protein |
Aldo_ket_red domain-containing protein |
Bombyx mori | 5az0_a | H9JJU9 | 100.00 | 1.80E-43 | 1.20E-47 | 313.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | AKR4C9 At2g37770 F13M22 T8P21.32 |
NADPH-dependent aldo-keto reductase, chloroplastic (AtChlAKR) (EC 1.1.1.-) (Aldo-keto reductase family 4 member C9) |
1.1.1.- | Arabidopsis thaliana | 3h7u_a | Q0PGJ6 | 100.00 | 1.00E-43 | 6.70E-48 | 312.50 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | STM2406 |
STM2406 |
Salmonella typhimurium | 3erp_b | Q8ZNA1 | 100.00 | 1.80E-50 | 1.20E-54 | 359.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | P100/11E |
9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) |
1.1.1.- | Leishmania major | 4f40_b | P22045 | 100.00 | 1.30E-42 | 8.20E-47 | 300.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | Tc00.1047053511287.49 |
9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) |
1.1.1.- | Trypanosoma cruzi | 4gie_a | Q4DJ07 | 100.00 | 2.00E-43 | 1.30E-47 | 305.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | BH1011 |
BH1011 |
Bacillus halodurans | 1ynp_b | Q9KE47 | 100.00 | 7.30E-46 | 4.70E-50 | 324.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | Aldo-keto reductase |
Aldo-keto reductase |
Firmicutes bacterium | 4q3m_d | A0A0B5KNF6 | 100.00 | 3.30E-45 | 2.10E-49 | 314.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | GL50803_007260 GL50803_7260 |
GL50803_007260 GL50803_7260 |
1.1.1.21 | Giardia intestinalis | 3krb_a | A8BGX6 | 100.00 | 9.50E-43 | 6.10E-47 | 307.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | yhdN BSU09530 |
Aldo-keto reductase YhdN (EC 1.1.1.-) (AKR11B) (General stress protein 69) (GSP69) |
1.1.1.- | Bacillus subtilis | 1pz1_b | P80874 | 100.00 | 8.60E-48 | 5.50E-52 | 339.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | Akr7a2 Afar Akr7a5 |
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase) |
1.1.1.n11 | Mus musculus | 2c91_c | Q8CG76 | 100.00 | 2.60E-46 | 1.70E-50 | 330.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | dkgA |
2,5-diketo-D-gluconic acid reductase A (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (EC 1.1.1.346) (AKR5C) |
1.1.1.346 | Corynebacterium sp. | 1a80_a | P06632 | 100.00 | 3.60E-43 | 2.30E-47 | 302.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | gpr mgrA yghZ b3001 JW2970 |
L-glyceraldehyde 3-phosphate reductase (GAP reductase) (EC 1.1.1.-) |
1.1.1.- | Escherichia coli | 3n6q_e | Q46851 | 100.00 | 5.30E-49 | 3.40E-53 | 349.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YNL331C | AAD14 | SGDID:S000005275 | PA4992 |
PA4992 |
Pseudomonas aeruginosa | 4exa_f | Q9HUH3 | 100.00 | 6.10E-42 | 3.90E-46 | 296.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | Kcnab2 Ckbeta2 Kcnb3 |
Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) |
1.1.1.- | Rattus norvegicus | 1exb_a | P62483 | 100.00 | 2.50E-48 | 1.60E-52 | 343.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | cpr-c1 |
NADPH-dependent conjugated polyketone reductase C1 (CPR) (2-dehydropantolactone reductase (A-specific)) (EC 1.1.1.168) (Ketopantoyl-lactone reductase) |
1.1.1.168 | Candida parapsilosis | 3wg6_a | Q76L37 | 100.00 | 3.70E-43 | 2.40E-47 | 306.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | MSMEG_2407 MSMEI_2346 |
Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346 (EC 1.-.-.-) |
Mycolicibacterium smegmatis | 2wzm_b | A0QV09 | 100.00 | 1.80E-43 | 1.10E-47 | 304.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | ytbE BSU29050 |
Uncharacterized oxidoreductase YtbE (EC 1.-.-.-) |
Bacillus subtilis | 3b3d_c | O34678 | 100.00 | 1.00E-44 | 6.50E-49 | 316.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | PR |
Perakine reductase (EC 1.1.1.317) |
1.1.1.317 | Rauvolfia serpentina | 3uyi_a | Q3L181 | 100.00 | 2.00E-48 | 1.30E-52 | 344.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | dkgB SMc00101 |
dkgB SMc00101 |
1.1.1.274 | Rhizobium meliloti | 3up8_a | Q92RC6 | 100.00 | 3.00E-44 | 1.90E-48 | 311.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | AKR1D1 SRD5B1 |
Aldo-keto reductase family 1 member D1 (EC 1.3.1.3) (3-oxo-5-beta-steroid 4-dehydrogenase) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase) |
1.3.1.3 | Homo sapiens | Liver Disease,Cholestasis-Lymphedema Syndrome,Leber Plus Disease,Bile Acid Synthesis Defect, Congenital, 3,Bile Acid Synthesis Defect, Congenital, 2,Congenital Bile Acid Synthesis Defect,Alpha-Methylacyl-Coa Racemase Deficiency |
3buv_a | P51857 | ENSG00000122787 | AKR1D1 | 100.00 | 3.60E-44 | 2.30E-48 | 315.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL331C | AAD14 | SGDID:S000005275 | GOX0644 |
GOX0644 |
1.1.1.- | Gluconobacter oxydans | 3wbw_a | Q5FT75 | 100.00 | 5.30E-45 | 3.40E-49 | 314.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | Aldo-keto reductase 1 |
Aldo-keto reductase 1 |
Coptotermes gestroi | 5ket_a | A0A140CVV2 | 100.00 | 1.70E-42 | 1.10E-46 | 306.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | akr2e AKR2E4 |
Aldo-keto reductase AKR2E4 (EC 1.1.1.-) (3-dehydroecdysone reductase) (Aldo-keto reductase 2E) |
1.1.1.- | Bombyx mori | 3wcz_a | H9JTG9 | 100.00 | 3.80E-43 | 2.40E-47 | 306.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | Bpro_4249 |
Bpro_4249 |
Polaromonas | 4xk2_a | Q124A1 | 100.00 | 9.80E-48 | 6.30E-52 | 341.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | ydhF STM1439 |
ydhF STM1439 |
Salmonella typhimurium | 4r9o_b | Q8ZPN5 | 100.00 | 3.70E-47 | 2.40E-51 | 331.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | ARA1 YBR149W YBR1127 |
D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC 1.1.1.117) (AKR3C) |
1.1.1.117 | Saccharomyces cerevisiae | 4ijc_b | P38115 | 100.00 | 2.50E-42 | 1.60E-46 | 304.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | Akr1b4 EWB00_003887 |
Akr1b4 EWB00_003887 |
1.1.1.21 | Schistosoma japonicum | 4hbk_a | Q5DD64 | 100.00 | 2.70E-43 | 1.70E-47 | 311.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL331C | AAD14 | SGDID:S000005275 | TM_1743 |
TM_1743 |
Thermotoga maritima | 5dan_a | Q9X265 | 100.00 | 9.10E-47 | 5.90E-51 | 324.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | CCNA_02590 |
CCNA_02590 |
Caulobacter vibrioides | 6gtm_b | A0A0H3C9H2 | 100.00 | 4.40E-46 | 2.80E-50 | 325.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | AR3 100857058 ZEAMMB73_Zm00001d038449 |
AR3 100857058 ZEAMMB73_Zm00001d038449 |
Zea mays | 5jgw_a | E9JVD4 | 100.00 | 5.00E-44 | 3.20E-48 | 313.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | Rv2971 |
Uncharacterized oxidoreductase Rv2971 (EC 1.-.-.-) |
Mycobacterium tuberculosis | 4otk_a | P9WQA5 | 100.00 | 4.00E-45 | 2.60E-49 | 318.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL331C | AAD14 | SGDID:S000005275 | Akr1c13 |
Aldo-keto reductase family 1 member C13 (EC 1.1.1.-) |
1.1.1.- | Mus musculus | 6m7k_a | Q8VC28 | 100.00 | 1.80E-43 | 1.10E-47 | 310.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |