Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YOR197W | MCA1 | SGDID:S000005723 | MALT1 MLT |
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) |
3.4.22.- | Homo sapiens | Gastrointestinal Lymphoma,Cheilitis,Peanut Allergy,Spleen Cancer,Lung Lymphoma,Leukocyte Disease,Chronic Mucocutaneous Candidiasis,Primary Cutaneous Marginal Zone B-Cell Lymphoma,B-Cell Lymphoma,Orbit Lymphoma,Gallbladder Lymphoma,Combined Immunodeficiency,Combined T And B Cell Immunodeficiency,Immunodeficiency 11,Duodenitis,Gastric Lymphoma,Phaeohyphomycosis,Central Nervous System Lymphoma,Immunodeficiency 12,Nodal Marginal Zone B-Cell Lymphoma,Orofaciodigital Syndrome Viii,Lymphoma, Non-Hodgkin, Familial,Lymphoma, Mucosa-Associated Lymphoid Type,Diffuse Large B-Cell Lymphoma,Mantle Cell Lymphoma,Marginal Zone B-Cell Lymphoma,Splenic Marginal Zone Lymphoma,Lymphoid Interstitial Pneumonia,Lymphoma,Alpha Chain Disease,Mastoiditis |
3uoa_c | Q9UDY8 | ENSG00000172175 | MALT1 | 99.70 | 4.20E-22 | 3.10E-26 | 194.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR197W | MCA1 | SGDID:S000005723 | CASP3 CPP32 |
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] |
3.4.22.56 | Homo sapiens | Skin Melanoma,Liver Disease,Bone Deterioration Disease,Heart Disease,Endometrial Cancer,Cowpox,Autosomal Dominant Polycystic Kidney Disease,Squamous Cell Carcinoma,Hypertensive Heart Disease,Ocular Melanoma,Vascular Disease,Retinitis Pigmentosa,Lung Cancer Susceptibility 3,Kagami-Ogata Syndrome,Myopathy,Mucositis,Status Epilepticus,Adenoid Cystic Carcinoma,Nephrosclerosis,Spinal Cord Injury,Non-Alcoholic Fatty Liver Disease,Traumatic Brain Injury,Nodal Marginal Zone Lymphoma,Polycystic Kidney Disease,Melanoma,Prion Disease,Leukemia, Chronic Myeloid,Thyroid Gland Anaplastic Carcinoma,Clubfoot,Fatty Liver Disease,Peripheral Nervous System Neoplasm,Bone Sarcoma,Encephalomalacia,Alzheimer Disease,Hepatoblastoma,Myocardial Infarction,Ectodermal Dysplasia,B-Cell Lymphoma,Stroke, Ischemic,Amyotrophic Lateral Sclerosis 1,Ovary Sarcoma,Oral Cancer,Oral Lichen Planus,T-Cell Lymphoblastic Leukemia/Lymphoma,Carbuncle,Amelogenesis Imperfecta,Pulmonary Emphysema,Human Cytomegalovirus Infection,Yellow Fever,Retinal Cancer,Pelvic Varices,Retinitis Pigmentosa 18,Transient Cerebral Ischemia,Varicocele,Lymphatic System Disease,Alcoholic Hepatitis,Spinal Muscular Atrophy,Colon Adenocarcinoma,Muscular Atrophy,Neuroblastoma,Retinal Ischemia,Retinal Vascular Disease,Leukemia, Acute Myeloid,Carotid Artery Occlusion,Bone Marrow Cancer,Leber Plus Disease,Leukemia, Acute Lymphoblastic,Cataract,Papilloma,Autonomic Nervous System Neoplasm,Sudden Infant Death Syndrome,Pneumococcal Meningitis,Pigmented Villonodular Synovitis,Idiopathic Neutropenia,Actinomycosis,Bladder Cancer,Brain Cancer,Monocytic Leukemia,Reticulosarcoma,Ehrlichiosis,Oropharynx Cancer,Cervix Carcinoma,Pneumoconiosis,Newcastle Disease,Nervous System Disease,Legionellosis,Ovarian Cancer,Burkitt Lymphoma,Fixed Drug Eruption,Vascular Dementia,Testicular Cancer,Eye Disease,Acute Megakaryocytic Leukemia,Heterophyiasis,Breast Cancer,Glioblastoma,Squamous Cell Carcinoma, Head And Neck,Malignant Astrocytoma,High Grade Glioma,Lower Lip Cancer,Brain Glioblastoma Multiforme,Parkinson Disease, Late-Onset,Colorectal Cancer,Peripheral Nervous System Disease,Nervous System Cancer,Ectodermal Dysplasia 10b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive,Hepatocellular Carcinoma,Premature Menopause,Keratoacanthoma,Malignant Peripheral Nerve Sheath Tumor,Cardiomyopathy, Familial Hypertrophic, 2,Occlusion Precerebral Artery,Pheochromocytoma,Breast Fibrosarcoma,Brain Injury,Tendinopathy,Hydrocephalus,Rhabdomyosarcoma,Pick Disease Of Brain,Ischemia,Intracranial Aneurysm,Tongue Disease,Ovarian Disease,Teratocarcinoma,Macular Degeneration, Age-Related, 1,Asphyxia Neonatorum,Spotted Fever,Sarcoma,Fanconi Anemia, Complementation Group A,Acute Laryngopharyngitis,Liposarcoma,Prostatitis,Skin Carcinoma,Gastric Cancer,Breast Adenocarcinoma,Breast Disease,Cone-Rod Dystrophy 2,Prostate Cancer,Disease Of Mental Health,Creutzfeldt-Jakob Disease,Cervical Cancer,Toxic Encephalopathy,Panniculitis,Thrombocytopenia,Dentatorubral-Pallidoluysian Atrophy,Lung Benign Neoplasm,Lymphadenitis,Retinoblastoma,Cervical Adenocarcinoma,Sensory System Disease,Bladder Urothelial Carcinoma,Lymphoma, Non-Hodgkin, Familial,Malaria,Neural Tube Defects,Hypotrichosis 1,Esophageal Cancer,Testicular Torsion,Myelodysplastic Syndrome,Fetal Alcohol Syndrome,Fetal Alcohol Spectrum Disorder,Mantle Cell Lymphoma,Krabbe Disease,Gastrointestinal Stromal Tumor,Hypothyroidism, Congenital, Nongoitrous, 6,Diabetic Encephalopathy,Cardiomyopathy, Familial Hypertrophic, 1,Colorectal Adenocarcinoma,Tongue Squamous Cell Carcinoma,Acute Promyelocytic Leukemia,Huntington Disease,Inflammatory Myofibroblastic Tumor,Colon Adenoma,Nasopharyngeal Carcinoma,Wilms Tumor 1,Ectodermal Dysplasia 1, Hypohidrotic, X-Linked,Hypertension, Essential,Autism Spectrum Disorder,Lymphoma,Metachromatic Leukodystrophy,Lipoprotein Quantitative Trait Locus,Lymphatic System Cancer,Kabuki Syndrome 1,Kaposi Sarcoma,Cardiomyopathy, Familial Hypertrophic, 25,Intracranial Berry Aneurysm,Alexander Disease,Leukemia, Chronic Lymphocytic,Amelogenesis Imperfecta, Type Ig,Ataxia-Telangiectasia,Myeloma, Multiple,Medulloblastoma,Spinal Disease,Autism,Lung Cancer,Helicobacter Pylori Infection,Osteogenic Sarcoma,Pancreatic Cancer |
2j30_a | P42574 | 99.70 | 1.80E-21 | 1.40E-25 | 178.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YOR197W | MCA1 | SGDID:S000005723 | MCA2 Tb927.6.940 |
Metacaspase-2 (EC 3.4.22.-) (TbMCA2) [Cleaved into: Large subunit p20; Small subunit p10] |
3.4.22.- | Trypanosoma brucei | 4af8_a | Q585F3 | 99.80 | 2.10E-24 | 1.60E-28 | 209.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | Drice ICE CG7788 |
Caspase (EC 3.4.22.-) (drICE) [Cleaved into: Caspase subunit p21; Caspase subunit p12] |
3.4.22.- | Drosophila melanogaster | 3sir_b | O01382 | 99.70 | 1.20E-22 | 8.80E-27 | 187.40 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | MCA1 YCA1 YOR197W |
Metacaspase-1 (EC 3.4.22.-) [Cleaved into: Large subunit p20; Small subunit p10] |
3.4.22.- | Saccharomyces cerevisiae | 4f6o_a | Q08601 | 100.00 | 4.50E-38 | 3.30E-42 | 305.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | CASP1_SPOFR |
Caspase-1 (EC 3.4.22.-) [Cleaved into: Caspase-1 subunit p19/18; Caspase-1 subunit p12] |
3.4.22.- | Spodoptera frugiperda | 1m72_a | P89116 | 99.80 | 1.10E-23 | 7.80E-28 | 194.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | CASP6 MCH2 |
Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11] |
3.4.22.59 | Homo sapiens | Alzheimer Disease,Thoracic Cancer,Dystrophinopathies,Prostate Cancer,Cardiomyopathy, Familial Hypertrophic, 1,Huntington Disease |
3od5_a | P55212 | 99.70 | 7.50E-22 | 5.70E-26 | 184.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YOR197W | MCA1 | SGDID:S000005723 | Dronc Nc CG8091 |
Caspase Dronc (EC 3.4.22.-) (NEDD2-like caspase) [Cleaved into: Caspase Nc subunit 1; Caspase Nc subunit 2] |
3.4.22.- | Drosophila melanogaster | 2fp3_a | Q9XYF4 | 99.70 | 1.40E-22 | 1.00E-26 | 192.90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | CASP7 MCH3 |
Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] |
3.4.22.60 | Homo sapiens | Alzheimer Disease,Legionellosis,Ovarian Cancer,Breast Cancer,Colorectal Cancer,Hepatocellular Carcinoma,Type 1 Diabetes Mellitus 17,Acute Laryngopharyngitis,Breast Adenocarcinoma,Prostate Cancer,Lymphoma, Non-Hodgkin, Familial,Dyskeratosis Congenita, Autosomal Dominant 3,Cardiomyopathy, Familial Hypertrophic, 1,Acute Promyelocytic Leukemia,Lung Cancer,Pancreatic Cancer |
1f1j_b | P55210 | 99.70 | 3.80E-23 | 2.80E-27 | 195.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YOR197W | MCA1 | SGDID:S000005723 | GSU0716 |
GSU0716 |
Geobacter sulfurreducens | 3bij_a | Q74F93 | 99.70 | 1.20E-21 | 8.80E-26 | 183.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YOR197W | MCA1 | SGDID:S000005723 | ced-3 C48D1.2 |
Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13] |
3.4.22.60 | Caenorhabditis elegans | 4m9r_a | P42573 | 99.70 | 8.70E-22 | 6.50E-26 | 186.30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | CASP8 MCH5 |
Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] |
3.4.22.61 | Homo sapiens | Adult Hepatocellular Carcinoma,Bone Disease,Cowpox,Saethre-Chotzen Syndrome,Vascular Disease,Lung Cancer Susceptibility 3,Melanoma,Thyroid Gland Anaplastic Carcinoma,Clubfoot,Peripheral Nervous System Neoplasm,Alzheimer Disease,Avian Influenza,Ectodermal Dysplasia,B-Cell Lymphoma,T-Cell Lymphoblastic Leukemia/Lymphoma,Familial Ovarian Cancer,Colon Adenocarcinoma,Post-Transplant Lymphoproliferative Disease,Neuroblastoma,Acute Leukemia,Leukemia, Acute Myeloid,Leukemia, Acute Lymphoblastic,Thoracic Cancer,Autonomic Nervous System Neoplasm,Dystrophinopathies,Bladder Cancer,Brain Cancer,Autoimmune Lymphoproliferative Syndrome,Oropharynx Cancer,Herpes Simplex,Pneumoconiosis,Hypersensitivity Reaction Type Iv Disease,Oral Cavity Cancer,Legionellosis,Ovarian Cancer,Burkitt Lymphoma,Breast Cancer,Squamous Cell Carcinoma, Head And Neck,Molluscum Contagiosum,High Grade Glioma,Parkinson Disease, Late-Onset,Colorectal Cancer,Peripheral Nervous System Disease,Hepatocellular Carcinoma,Human Immunodeficiency Virus Type 1,Tendinopathy,Rhabdomyosarcoma,Large Granular Lymphocyte Leukemia,Sarcoma,Skin Carcinoma,Gastric Cancer,Breast Adenocarcinoma,Cone-Rod Dystrophy 2,Prostate Cancer,Disease Of Mental Health,Cervical Cancer,Skin Disease,Multiple Sclerosis,Childhood Medulloblastoma,Lymphoma, Non-Hodgkin, Familial,Neural Tube Defects,Esophageal Cancer,Inflammatory Bowel Disease,Chronic Mountain Sickness,Myelodysplastic Syndrome,Ewing Sarcoma,Primary Progressive Multiple Sclerosis,Gastrointestinal Stromal Tumor,Cardiomyopathy, Familial Hypertrophic, 1,Acute Promyelocytic Leukemia,Huntington Disease,Follicular Lymphoma,Renal Cell Carcinoma, Nonpapillary,Caspase 8 Deficiency,Leukemia, Chronic Lymphocytic,Myeloma, Multiple,Medulloblastoma,Lymphoproliferative Syndrome,Lung Cancer,Asthma,Pancreatic Cancer |
4jj7_a | Q14790 | ENSG00000064012 | CASP8 | 99.70 | 1.30E-21 | 9.90E-26 | 182.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR197W | MCA1 | SGDID:S000005723 | casp3a |
casp3a |
Danio rerio | 5jft_a | B8JK21 | 99.70 | 1.90E-22 | 1.40E-26 | 184.60 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | ||||
YOR197W | MCA1 | SGDID:S000005723 | CASP1 |
Caspase-1 (EC 3.4.22.-) [Cleaved into: Caspase-1 subunit p19/18; Caspase-1 subunit p12] |
3.4.22.- | Spodoptera frugiperda | 1m72_c | P89116 | 99.70 | 7.80E-22 | 5.90E-26 | 183.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR197W | MCA1 | SGDID:S000005723 | CASP9 MCH6 |
Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10] |
3.4.22.62 | Homo sapiens | Endometrial Cancer,Lung Cancer Susceptibility 3,Melanoma,Leukemia, Chronic Myeloid,Diabetes Mellitus,Clubfoot,Peripheral Nervous System Neoplasm,Alzheimer Disease,B-Cell Lymphoma,Stroke, Ischemic,T-Cell Lymphoblastic Leukemia/Lymphoma,Carbuncle,Varicocele,Colon Adenocarcinoma,Neuroblastoma,Leukemia, Acute Myeloid,Lymphoproliferative Syndrome 1,Thoracic Cancer,Autonomic Nervous System Neoplasm,Dilated Cardiomyopathy,Dystrophinopathies,Bladder Cancer,Newcastle Disease,Ovarian Cancer,Burkitt Lymphoma,Acute Megakaryocytic Leukemia,Breast Cancer,Squamous Cell Carcinoma, Head And Neck,Parkinson Disease, Late-Onset,Colorectal Cancer,Peripheral Nervous System Disease,Hepatocellular Carcinoma,Rhabdomyosarcoma,Ischemia,Sarcoma,Gastric Cancer,Breast Adenocarcinoma,Prostate Cancer,Disease Of Mental Health,Cholangiocarcinoma,Cervical Cancer,Toxic Encephalopathy,Type 2 Diabetes Mellitus,Lymphoma, Non-Hodgkin, Familial,Neural Tube Defects,Esophageal Cancer,Chronic Mountain Sickness,Mantle Cell Lymphoma,Gastrointestinal Stromal Tumor,Varicose Veins,Cardiomyopathy, Familial Hypertrophic, 1,Acute Promyelocytic Leukemia,Huntington Disease,Renal Cell Carcinoma, Nonpapillary,Nasopharyngeal Carcinoma,Myeloma, Multiple,Medulloblastoma,Melanoma, Uveal,Lung Cancer,Pancreatic Cancer |
3v3k_a | P55211 | ENSG00000132906 | CASP9 | 99.70 | 1.20E-21 | 8.80E-26 | 182.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |