Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YOR204W | DED1 | SGDID:S000005730 | RECQL4 RECQ4 |
ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4) |
3.6.4.12 | Homo sapiens | Bone Development Disease,Saethre-Chotzen Syndrome,Malignant Fibrous Histiocytoma,Plasma Cell Neoplasm,Uterine Adnexa Cancer,Rothmund-Thomson Syndrome, Type 2,Synostosis,B-Lymphoblastic Leukemia/Lymphoma With Etv6-Runx1,Familial Retinoblastoma,Neutropenia,Radioulnar Synostosis,Baller-Gerold Syndrome,Craniosynostosis,Telangiectasis,B-Lymphoblastic Leukemia/Lymphoma With T,Cataract,Combined Immunodeficiency,Dyskeratosis Congenita,Skin Atrophy,Werner Syndrome,Lens Disease,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Pediatric Osteosarcoma,Juxtacortical Osteosarcoma,Bone Osteosarcoma,Poikiloderma With Neutropenia,Rothmund-Thomson Syndrome, Type 1,Pharynx Squamous Cell Carcinoma,Parietal Foramina,Li-Fraumeni Syndrome,Myeloma, Multiple,Bloom Syndrome,Osteogenic Sarcoma,Rapadilino Syndrome |
5lst_a | O94761 | ENSG00000160957 | RECQL4 | 99.80 | 1.00E-24 | 7.60E-29 | 244.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | HAS1 YMR290C |
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1) |
3.6.4.13 | Saccharomyces cerevisiae | 5z3g_y | Q03532 | 99.90 | 9.40E-30 | 7.20E-34 | 274.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | PRP28 YDR243C YD8419.10C |
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8) |
3.6.4.13 | Saccharomyces cerevisiae | 4w7s_a | P23394 | 99.90 | 3.30E-28 | 2.50E-32 | 257.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | DDX19B DBP5 DDX19 TDBP |
ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B) |
3.6.4.13 | Homo sapiens | Anterior Horn Cell Disease,Lethal Congenital Contracture Syndrome 1,Lethal Congenital Contracture Syndrome |
6b4j_e | Q9UMR2 | ENSG00000157349 | DDX19B | 99.80 | 2.40E-26 | 1.90E-30 | 240.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | DDX3X DBX DDX3 |
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2) |
3.6.4.13 | Homo sapiens | Hepatitis C,Hepatitis B,Venezuelan Equine Encephalitis,Encephalitis,Corpus Callosum, Agenesis Of, With Facial Anomalies And Robin Sequence,Lymphocytic Choriomeningitis,Rare Genetic Intellectual Disability,Hepatitis,Infratentorial Cancer,Ddx3x-Related Neurodevelopmental Disorder,Basal Cell Nevus Syndrome,Precursor T-Cell Acute Lymphoblastic Leukemia,Breast Cancer,Microcephaly,Hepatitis C Virus,Alacrima, Achalasia, And Mental Retardation Syndrome,Noonan Syndrome 3,Disease Of Mental Health,Adult Medulloblastoma,Childhood Medulloblastoma,Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type,Ewing Sarcoma,Syndromic Intellectual Disability,Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome,Medulloblastoma,Systemic Epstein-Barr Virus-Positive T-Cell Lymphoma Of Childhood,Cerebellar Hypoplasia/Atrophy, Epilepsy, And Global Developmental Delay |
2i4i_a | O00571 | ENSG00000215301 | DDX3X | 99.90 | 1.20E-29 | 9.00E-34 | 263.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | BLM RECQ2 RECQL3 |
Bloom syndrome protein (EC 3.6.4.12) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3) |
3.6.4.12 | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Familial Colorectal Cancer,Inherited Cancer-Predisposing Syndrome,Wilms Tumor Predisposition,Ovarian Cancer,Breast Cancer,Hereditary Breast Ovarian Cancer Syndrome,Colorectal Cancer,Microcephaly,Werner Syndrome,Fanconi Anemia, Complementation Group A,Cone-Rod Dystrophy 2,Tumor Predisposition Syndrome,Syndromic Intellectual Disability,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Nijmegen Breakage Syndrome,Ataxia-Telangiectasia,Bloom Syndrome,Rapadilino Syndrome |
4o3m_a | P54132 | ENSG00000197299 | BLM | 99.80 | 2.90E-24 | 2.20E-28 | 239.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | DBP5 RAT8 YOR046C |
ATP-dependent RNA helicase DBP5 (EC 3.6.4.13) (DEAD box protein 5) (Helicase CA5/6) (Ribonucleic acid-trafficking protein 8) |
3.6.4.13 | Saccharomyces cerevisiae | 3pey_a | P20449 | 99.80 | 2.20E-26 | 1.70E-30 | 237.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | DDX23 |
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) |
3.6.4.13 | Homo sapiens | Retinitis Pigmentosa,Burn-Mckeown Syndrome,Distal Hereditary Motor Neuronopathy Type 2,Cockayne Syndrome,Spinal Muscular Atrophy, Type I |
4nho_a | Q9BUQ8 | ENSG00000174243 | DDX23 | 99.90 | 6.30E-29 | 4.80E-33 | 265.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | CTHT_0054430 |
CTHT_0054430 |
Chaetomium thermophilum | 5dtu_a | G0SBQ7 | 99.90 | 1.00E-27 | 7.80E-32 | 254.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YOR204W | DED1 | SGDID:S000005730 | RECQL RECQ1 RECQL1 |
ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1) |
3.6.4.12 | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Inherited Cancer-Predisposing Syndrome,Ovarian Cancer,Hereditary Breast Ovarian Cancer Syndrome,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Tumor Predisposition Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Bloom Syndrome,Rapadilino Syndrome |
2v1x_b | P46063 | ENSG00000004700 | RECQL | 99.80 | 2.20E-26 | 1.60E-30 | 252.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | recQ b3822 JW5855 |
ATP-dependent DNA helicase RecQ (EC 3.6.4.12) |
3.6.4.12 | Escherichia coli | 1oyw_a | P15043 | 99.80 | 2.40E-26 | 1.80E-30 | 248.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YOR204W | DED1 | SGDID:S000005730 | MJ0669 |
Probable ATP-dependent RNA helicase MJ0669 (EC 3.6.4.13) |
3.6.4.13 | Methanocaldococcus jannaschii | 1hv8_a | Q58083 | 99.90 | 1.60E-27 | 1.20E-31 | 242.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | cshA GT50_10605 |
cshA GT50_10605 |
Geobacillus stearothermophilus | 5ivl_b | A0A0K2H973 | 99.90 | 7.00E-30 | 5.40E-34 | 267.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YOR204W | DED1 | SGDID:S000005730 | EIF4A3 DDX48 KIAA0111 |
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] |
3.6.4.13 | Homo sapiens | Metaphyseal Chondrodysplasia, Schmid Type,Robin Sequence With Cleft Mandible And Limb Anomalies,Dysostosis,Vaginal Cancer,Neurodegeneration With Brain Iron Accumulation,Thrombocytopenia-Absent Radius Syndrome,Mandibulofacial Dysostosis, Guion-Almeida Type,Acrofacial Dysostosis |
6qdv_7 | P38919 | ENSG00000141543 | EIF4A3 | 99.90 | 2.50E-29 | 1.90E-33 | 258.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | vas vasa CG46283 |
ATP-dependent RNA helicase vasa (EC 3.6.4.13) (Antigen Mab46F11) |
3.6.4.13 | Drosophila melanogaster | 2db3_b | P09052 | 99.90 | 8.30E-31 | 6.40E-35 | 275.40 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | SUB2 YDL084W |
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 5sup_b | Q07478 | 99.90 | 1.10E-28 | 8.50E-33 | 254.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | DDX6 HLR2 RCK |
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) |
3.6.4.13 | Homo sapiens | Nodal Marginal Zone Lymphoma,Non-Specific Syndromic Intellectual Disability,Noonan Syndrome 3,Telecanthus,Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies |
4ct4_b | P26196 | ENSG00000110367 | DDX6 | 99.90 | 4.90E-29 | 3.80E-33 | 255.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | PRPF19 NMP200 PRP19 SNEV |
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) |
2.3.2.27 | Homo sapiens | Retinitis Pigmentosa 19,Poikiloderma With Neutropenia |
6qdv_v | Q9UMS4 | ENSG00000110107 | PRPF19 | 99.80 | 2.40E-24 | 1.80E-28 | 254.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | BmVLG |
BmVLG |
3.6.4.13 | Bombyx mori | 4d25_a | O01378 | 99.90 | 2.90E-31 | 2.30E-35 | 278.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | EIF4A1 DDX2A EIF4A |
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) |
3.6.4.13 | Homo sapiens | Ovary Sarcoma |
5zc9_a | P60842 | ENSG00000161960 | EIF4A1 | 99.90 | 1.50E-28 | 1.20E-32 | 253.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR204W | DED1 | SGDID:S000005730 | PRP5 RNA5 YBR237W YBR1603 |
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 4ljy_a | P21372 | 99.90 | 5.60E-29 | 4.30E-33 | 266.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | DR_1289 |
DR_1289 |
3.6.4.12 | Deinococcus radiodurans | 4q47_a | Q9RUU2 | 99.90 | 4.00E-27 | 3.10E-31 | 255.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | RNA helicase (EC 3.6.4.13) |
RNA helicase (EC 3.6.4.13) |
3.6.4.13 | Gallus gallus | 5jaj_a | G0YYQ5 | 99.80 | 1.70E-24 | 1.30E-28 | 241.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | MTR4 DOB1 YJL050W J1158 |
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4) |
3.6.4.13 | Saccharomyces cerevisiae | 6ft6_mm | P47047 | 99.80 | 2.90E-26 | 2.10E-30 | 267.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | MSS116 YDR194C YD9346.05C |
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 3i5x_a | P15424 | 99.90 | 2.50E-28 | 1.90E-32 | 266.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | ST2459 STK_24590 |
ST2459 STK_24590 |
3.6.4.13 | Sulfurisphaera tokodaii | 2z0m_a | Q96XQ7 | 99.80 | 2.70E-25 | 2.10E-29 | 222.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | MSMEG_1757 |
MSMEG_1757 |
Mycolicibacterium smegmatis | 5v9x_a | A0QT91 | 99.80 | 7.80E-25 | 5.80E-29 | 251.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YOR204W | DED1 | SGDID:S000005730 | DHH1 YDL160C |
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1) |
3.6.4.13 | Saccharomyces cerevisiae | 1s2m_a | P39517 | 99.90 | 7.90E-29 | 6.10E-33 | 256.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | TIF1 TIF41A YKR059W; TIF2 TIF41B YJL138C J0660 |
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37) |
3.6.4.13 | Saccharomyces cerevisiae | 1fuu_b | P10081 | 99.90 | 4.00E-29 | 3.10E-33 | 258.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | dbp5 SPBC12C2.06 |
ATP-dependent RNA helicase dbp5 (EC 3.6.4.13) |
3.6.4.13 | Schizosaccharomyces pombe | 3fho_b | Q09747 | 99.80 | 3.60E-25 | 2.70E-29 | 238.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | UTP25 |
Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 |
pfam Family | PF06862 | 99.80 | 4.00E-24 | 3.00E-28 | 229.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
YOR204W | DED1 | SGDID:S000005730 | SKI2 YLR398C L8084.17 |
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 4buj_a | P35207 | 99.80 | 3.10E-25 | 2.30E-29 | 258.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR204W | DED1 | SGDID:S000005730 | PPIE CYP33 |
Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E) |
5.2.1.8 | Homo sapiens | 6icz_y | Q9UNP9 | ENSG00000084072 | PPIE | 99.80 | 2.60E-24 | 1.90E-28 | 254.60 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |