| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YPL176C | TRE1 | SGDID:S000006097 | TFRC |
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] |
Homo sapiens | Metal Metabolism Disorder,Diphtheria,Neuritis,Iron Deficiency Anemia,Nephrotic Syndrome,Primary Cutaneous T-Cell Lymphoma,Amyotrophic Lateral Sclerosis 1,Occlusion Of Gallbladder,Neutropenia,Brain Edema,Neurodegeneration With Brain Iron Accumulation,Iron Metabolism Disease,Hemochromatosis Type 2,Leukemia, Acute Myeloid,Mucopolysaccharidosis-Plus Syndrome,Combined Immunodeficiency,Nutritional Deficiency Disease,Polycythemia,Retinal Degeneration,Hereditary Spherocytosis,Combined T And B Cell Immunodeficiency,Parasitic Protozoa Infectious Disease,Brain Cancer,Porphyria,Ehrlichiosis,Hemoglobinopathy,Sickle Cell Disease,Siderosis,Congenital Dyserythropoietic Anemia,Megaloblastic Anemia,Diamond-Blackfan Anemia,Aplastic Anemia,Iga Glomerulonephritis,Gastric Adenosquamous Carcinoma,Anemia, Congenital Dyserythropoietic, Type Ia,Gliosarcoma,Colorectal Cancer,Hemolytic Anemia,Folic Acid Deficiency Anemia,Human Immunodeficiency Virus Type 1,Deficiency Anemia,Porphyria Cutanea Tarda,Microcytic Anemia,Friedreich Ataxia,Disease Of Mental Health,Protoporphyria, Erythropoietic, 1,Body Mass Index Quantitative Trait Locus 11,Alpha-Thalassemia,Hemochromatosis, Type 3,Thrombocytopenia,Aceruloplasminemia,Rheumatoid Arthritis,Multiple Sclerosis,Human Granulocytic Anaplasmosis,Hemochromatosis, Type 1,Disease By Infectious Agent,Hemoglobin H Disease,Beta-Thalassemia,Argentine Hemorrhagic Fever,Bolivian Hemorrhagic Fever,Lymphoma, Non-Hodgkin, Familial,Congenital Hypothyroidism,Anemia, Sideroblastic, 1,Malaria,Restless Legs Syndrome,Developmental And Epileptic Encephalopathy 26,Hemochromatosis, Type 4,Immune Deficiency Disease,Hypochromic Microcytic Anemia,Myelodysplastic Syndrome,Spastic Paraplegia 38, Autosomal Dominant,Immunodeficiency 46,Leukemia, Chronic Lymphocytic,Mucopolysaccharidosis, Type Ii,Paroxysmal Nocturnal Hemoglobinuria,Atransferrinemia,Celiac Disease 1,Polycythemia Vera |
1cx8_d | P02786 | ENSG00000072274 | TFRC | 100.00 | 8.30E-67 | 6.30E-71 | 612.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL176C | TRE1 | SGDID:S000006097 | amp |
amp |
Aneurinibacillus | 5ib9_a | A2V759 | 100.00 | 1.70E-37 | 1.30E-41 | 345.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL176C | TRE1 | SGDID:S000006097 | NAALADL1 NAALADASEL NAALADL |
Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) |
3.4.11.- | Homo sapiens | Arthrogryposis, Distal, Type 4 |
4twe_a | Q9UQQ1 | ENSG00000168060 | NAALADL1 | 100.00 | 3.50E-66 | 2.70E-70 | 615.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YPL176C | TRE1 | SGDID:S000006097 | FOLH1 FOLH NAALAD1 PSM PSMA GIG27 |
Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase) |
3.4.17.21 | Homo sapiens | Bladder Lateral Wall Cancer,Urethral Stricture,Suppression Of Tumorigenicity 12,Lymphocele,Bone Epithelioid Hemangioma,Lymph Node Carcinoma,Alzheimer Disease,Amyotrophic Lateral Sclerosis 1,Prostate Small Cell Carcinoma,Maxillary Sinus Adenoid Cystic Carcinoma,Prostate Disease,Male Reproductive System Disease,Canavan Disease,Middle Lobe Syndrome,Anthracosilicosis,Prostate Neuroendocrine Neoplasm,Colorectal Cancer,Prostate Cancer,Male Reproductive Organ Cancer,Schizophrenia,Neural Tube Defects,Laurence-Moon Syndrome,Huntington Disease,Villous Adenoma,Renal Cell Carcinoma, Nonpapillary |
1z8l_b | Q04609 | ENSG00000086205 | FOLH1 | 100.00 | 8.90E-68 | 6.80E-72 | 626.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YPL176C | TRE1 | SGDID:S000006097 | ncstn DICPUDRAFT_96800 |
Nicastrin (DpNCT) |
Dictyostelium purpureum | 4r12_a | F0ZBA6 | 99.80 | 2.20E-23 | 1.70E-27 | 239.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL176C | TRE1 | SGDID:S000006097 | Sama_0919 |
Sama_0919 |
Shewanella amazonensis | 3iib_a | A1S420 | 100.00 | 2.00E-36 | 1.50E-40 | 339.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL176C | TRE1 | SGDID:S000006097 | NAALAD2 |
N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) |
3.4.17.21 | Homo sapiens | Fetal Erythroblastosis |
3fed_a | Q9Y3Q0 | ENSG00000077616 | NAALAD2 | 100.00 | 1.40E-70 | 1.00E-74 | 651.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YPL176C | TRE1 | SGDID:S000006097 | NCSTN KIAA0253 UNQ1874/PRO4317 |
Nicastrin |
Homo sapiens | Sebaceous Gland Disease,Acne,Alzheimer Disease,Anal Canal Squamous Cell Carcinoma,Hidradenitis Suppurativa,Hidradenitis,Parkinson Disease, Late-Onset,Sweat Gland Disease,Pick Disease Of Brain,Disease Of Mental Health,Acne Inversa, Familial, 1,Dowling-Degos Disease |
4uis_a | Q92542 | ENSG00000162736 | NCSTN | 99.80 | 4.20E-26 | 3.20E-30 | 262.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |