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AnalogYeast
One stop shop for finding analogs for your favorite yeast protein

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YPR033C HTS1 / SGDID:S000006237
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YPR033C HTS1 SGDID:S000006237
hisS TTHA0712
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Thermus thermophilus
1ady_d P56194 100.00 7.80E-37 5.10E-41 304.30 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisZ BH3584
ATP phosphoribosyltransferase regulatory subunit
Bacillus halodurans
3od1_a Q9K6Z0 100.00 5.00E-37 3.30E-41 302.30 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
Prolyl-tRNA synthetase (EC 6.1.1.15)
Prolyl-tRNA synthetase (EC 6.1.1.15)
Onchocerca volvulus
6mn8_a A0A2K6VKP7 99.90 4.20E-30 2.80E-34 260.00 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proS MJ1238
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Methanocaldococcus jannaschii
1nj8_b Q58635 99.90 6.20E-30 4.00E-34 255.90 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
HARS1 HARS HRS
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Homo sapiens
Charles Bonnet Syndrome,Retinitis Pigmentosa,Myopathy,Neuritis,Tremor,Antisynthetase Syndrome,Polymyositis,Low Compliance Bladder,Myositis,Pathologic Nystagmus,Usher Syndrome Type 2,Bagassosis,Oculomotor Apraxia,Sensorineural Hearing Loss,Acute Interstitial Pneumonia,Neuropathy,Charcot-Marie-Tooth Disease,Peripheral Nervous System Disease,Usher Syndrome, Type Iiia,Microcephaly,Tooth Disease,Childhood Type Dermatomyositis,Alacrima, Achalasia, And Mental Retardation Syndrome,Disease Of Mental Health,Aceruloplasminemia,Usher Syndrome,Perrault Syndrome,Vertical Talus, Congenital,Usher Syndrome, Type Iiib,Spastic Ataxia,Charcot-Marie-Tooth Disease, Axonal, Type 2w,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Scoliosis,Ocular Motor Apraxia,Neuronopathy, Distal Hereditary Motor, Type Va
4g84_b P12081 ENSG00000170445 HARS1 100.00 1.00E-42 6.50E-47 351.20 1 1 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisS Ta0099
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Thermoplasma acidophilum
1wu7_a Q9HLX5 100.00 3.40E-39 2.20E-43 322.50 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisZ Psyc_0676
ATP phosphoribosyltransferase regulatory subunit
Psychrobacter arcticus
6ftt_b Q4FTX3 99.90 2.00E-32 1.30E-36 268.30 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
EPRS1 EPRS GLNS PARS QARS QPRS PIG32
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]
6.1.1.15,6.1.1.17, Homo sapiens
Mitochondrial Encephalomyopathy,Muscular Disease,X-Linked Recessive Disease,Chromosomal Disease,Physical Disorder,Glucose Metabolism Disease,Retinitis Pigmentosa,Myopathy,Amino Acid Metabolic Disorder,Connective Tissue Disease,Disorder Of Sexual Development,Robinow Syndrome, Autosomal Recessive 1,Inherited Metabolic Disorder,Muscle Tissue Disease,Charcot-Marie-Tooth Disease, Dominant Intermediate C,Neuromuscular Disease,Mitochondrial Myopathy,Mitochondrial Metabolism Disease,Infantile Liver Failure Syndrome,Antisynthetase Syndrome,Amyotrophic Lateral Sclerosis 1,Combined Oxidative Phosphorylation Deficiency 12,Angelman Syndrome,Eye Degenerative Disease,Microcephaly-Short Stature-Intellectual Disability-Facial Dysmorphism Syndrome,Charcot-Marie-Tooth Disease, Axonal, Type 2d,Motor Neuron Disease,Subependymal Glioma,Benign Ependymoma,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Epilepsy, Idiopathic Generalized 3,Congenital Nervous System Abnormality,Subependymal Giant Cell Astrocytoma,Cardiovascular System Disease,Auditory System Disease,Lung Disease,Acute Cystitis,Parasitic Protozoa Infectious Disease,Trichohepatoenteric Syndrome 1,Pleurisy,Immune System Disease,Nervous System Disease,Inner Ear Disease,Leukodystrophy,Eye Disease,Charcot-Marie-Tooth Disease,Charcot-Marie-Tooth Disease, Axonal, Type 2n,Early Myoclonic Encephalopathy,Peripheral Nervous System Disease,Microcephaly,Dysphagia,Central Nervous System Disease,Cerebral Degeneration,46 Xx Gonadal Dysgenesis,West Syndrome,Disease Of Mental Health,Leukodystrophy, Hypomyelinating, 15,Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1a,Respiratory System Disease,Microcephaly, Progressive, With Seizures And Cerebral And Cerebellar Atrophy,Integumentary System Disease,Polyomavirus-Associated Nephropathy,Disease By Infectious Agent,Deafness, Autosomal Recessive 89,Sensory System Disease,Usher Syndrome,Lennox-Gastaut Syndrome,Immune Deficiency Disease,Charcot-Marie-Tooth Disease, Axonal, Type 2u,Neonatal Period Electroclinical Syndrome,Early Infantile Epileptic Encephalopathy,X-Linked Monogenic Disease,Autosomal Recessive Disease,Autosomal Genetic Disease,Perrault Syndrome,Hemorrhagic Cystitis,Pulmonary Disease, Chronic Obstructive,Usher Syndrome, Type Iiib,Epilepsy, Idiopathic Generalized 2,Specific Developmental Disorder,Pervasive Developmental Disorder,Acquired Metabolic Disease,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Robinow Syndrome,Pontocerebellar Hypoplasia,Chromosome 16p11.2 Deletion Syndrome,Chromosomal Duplication Syndrome,Hypomyelinating Leukodystrophy,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes,Thrombosis,Neuronopathy, Distal Hereditary Motor, Type Va
4hvc_a P07814 ENSG00000136628 EPRS1 99.90 1.60E-30 1.00E-34 263.60 1 1 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proRS PFL0670c
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Plasmodium falciparum
4twa_a Q8I5R7 99.90 1.60E-29 1.00E-33 255.70 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisS TT_C0360
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Thermus thermophilus
1h4v_b P62374 100.00 3.40E-37 2.20E-41 306.90 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
Aaci_0923
Aaci_0923
6.1.1.21 Alicyclobacillus acidocaldarius
3rac_a C8WUX4 99.90 4.50E-29 2.90E-33 242.80 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
1MB.635
1MB.635
Cryptosporidium parvum
5f9z_a Q7YZ69 99.90 3.90E-30 2.50E-34 260.20 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisS b2514 JW2498
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Escherichia coli
1kmm_b P60906 100.00 1.20E-36 7.80E-41 303.30 0 0 0 0 0 0 0 1
YPR033C HTS1 SGDID:S000006237
ETH_00000045
ETH_00000045
6.1.1.15 Eimeria tenella
5xip_b U6KWI1 99.90 7.40E-29 4.80E-33 250.50 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
GL50803_0015983 GL50803_15983
GL50803_0015983 GL50803_15983
6.1.1.15 Giardia intestinalis
3ial_a A8BR89 99.90 1.30E-29 8.70E-34 256.30 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proS TTHA0115
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Thermus thermophilus
1h4s_b Q5SM28 99.90 1.70E-29 1.10E-33 254.10 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
GARS1 GARS
Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (Ap4A synthetase) (EC 2.7.7.-) (Glycyl-tRNA synthetase) (GlyRS) (Glycyl-tRNA synthetase 1)
6.1.1.14 Homo sapiens
Spinal Muscular Atrophy With Lower Extremity Predominance,Spinal Muscular Atrophy, Infantile, James Type,Charcot-Marie-Tooth Disease, Type 4a,Charcot-Marie-Tooth Disease Type 5,Charcot-Marie-Tooth Disease, Demyelinating, Type 1c,Cerebral Angioma,Charcot-Marie-Tooth Disease, Dominant Intermediate C,Neuromuscular Disease,Polymyositis,Myositis,Axonal Neuropathy,Neuronopathy, Distal Hereditary Motor, Type Iib,Spinal Muscular Atrophy,Charcot-Marie-Tooth Disease, Axonal, Type 2d,Motor Neuron Disease,Muscular Atrophy,Charcot-Marie-Tooth Disease, Axonal, Type 2l,Spastic Paraplegia 17, Autosomal Dominant,Neuropathy, Hereditary, With Liability To Pressure Palsies,Distal Hereditary Motor Neuropathies,Autosomal Recessive Distal Hereditary Motor Neuronopathy,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Distal Hereditary Motor Neuronopathy Type 2,Motor Peripheral Neuropathy,Bscl2-Related Neurologic Disorders/Seipinopathy,Gars1-Associated Axonal Neuropathy,Dermatomyositis,Neuropathy,Charcot-Marie-Tooth Disease,Charcot-Marie-Tooth Disease, Axonal, Type 2n,Peripheral Nervous System Disease,Thoracic Outlet Syndrome,Tooth Disease,Charcot-Marie-Tooth Disease, Demyelinating, Type 1b,Charcot-Marie-Tooth Disease And Deafness,Charcot-Marie-Tooth Disease, Recessive Intermediate B,Disease Of Mental Health,Brain Stem Infarction,Spinal Muscular Atrophy, Distal, Autosomal Recessive, 1,Charcot-Marie-Tooth Disease, Type 4b2,Scapuloperoneal Spinal Muscular Atrophy,Combined Oxidative Phosphorylation Deficiency 20,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive,Charcot-Marie-Tooth Disease, Axonal, Type 2b2,Charcot-Marie-Tooth Disease Type X,Charcot-Marie-Tooth Disease Intermediate Type,Spinal Muscular Atrophy, Distal, Autosomal Recessive, 2,Glycine Encephalopathy,Hereditary Motor And Sensory Neuropathy, Type Iic,Charcot-Marie-Tooth Disease, Axonal, Type 2u,Developmental And Epileptic Encephalopathy 29,Charcot-Marie-Tooth Disease, Axonal, Type 2f,Charcot-Marie-Tooth Disease, X-Linked Dominant, 1,Perrault Syndrome,Hypertrophic Neuropathy Of Dejerine-Sottas,Charcot-Marie-Tooth Disease, Axonal, Type 2i,Charcot-Marie-Tooth Disease, Demyelinating, Type 1d,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Hyperekplexia,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes,Neuronopathy, Distal Hereditary Motor, Type Va,Charcot-Marie-Tooth Disease, Axonal, Type 2b
2zt5_a P41250 ENSG00000106105 GARS1 99.90 9.50E-32 6.20E-36 276.10 1 1 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proS PA0956
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Pseudomonas aeruginosa
5ucm_b Q9I502 99.90 7.70E-31 5.00E-35 270.50 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
LMJF_18_1220
LMJF_18_1220
6.1.1.15 Leishmania major
5xil_a Q4QDS0 99.90 5.50E-29 3.60E-33 252.40 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
thrS b1719 JW1709
Threonine--tRNA ligase (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)
6.1.1.3 Escherichia coli
1kog_h P0A8M3 99.90 2.50E-28 1.60E-32 241.20 0 0 0 0 0 0 0 1
YPR033C HTS1 SGDID:S000006237
hisS all5012
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Nostoc sp.
3net_a Q8YMC2 100.00 7.50E-39 4.90E-43 323.00 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
Tc00.1047053507019.40
Tc00.1047053507019.40
6.1.1.21 Trypanosoma cruzi
3lc0_a Q4DA54 100.00 2.80E-40 1.80E-44 331.90 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proS MTH_611
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Methanothermobacter thermautotrophicus
1nj1_a O26708 99.90 6.00E-29 3.90E-33 251.00 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proS EF_2379
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Enterococcus faecalis
2j3l_a Q831W7 99.90 3.70E-31 2.40E-35 272.80 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisS
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Staphylococcus aureus
1qe0_a P60911 100.00 1.00E-36 6.80E-41 303.60 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
hisS ABSDF3000
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
6.1.1.21 Acinetobacter baumannii
5e3i_a B0VKR7 100.00 8.00E-36 5.20E-40 298.20 0 0 0 0 0 0 0 0
YPR033C HTS1 SGDID:S000006237
proS RPA2928
Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
6.1.1.15 Rhodopseudomonas palustris
2i4l_c Q6N5P6 99.90 6.60E-30 4.30E-34 256.80 0 0 0 0 0 0 0 0

Weizmann Institute of Science | Maya Schuldiner Lab