| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YPR085C | ASA1 | SGDID:S000006289 | LRRK2 PARK8 |
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) |
2.7.11.1,3.6.5.-, | Homo sapiens | Supranuclear Palsy, Progressive, 1,Rem Sleep Behavior Disorder,Spinocerebellar Atrophy,Tremor,Prion Disease,Gaucher'S Disease,Hereditary Late-Onset Parkinson Disease,Sphingolipidosis,Klippel-Feil Syndrome 1,Alzheimer Disease,Ulnar Nerve Lesion,Radial Nerve Lesion,Amyotrophic Lateral Sclerosis 1,Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1,Parkinsonism,Movement Disease,Isolated Klippel-Feil Syndrome,Testicular Disease,Essential Tremor,Von Economo'S Disease,Dementia,Lrrk2 Parkinson Disease,Sleep Disorder,Dystonia,Nervous System Disease,Klippel-Feil Syndrome,Crohn'S Disease,Parkinson Disease, Late-Onset,Peripheral Nervous System Disease,Parkinson Disease 3, Autosomal Dominant,Parkinson Disease 1, Autosomal Dominant,Athetosis,Pick Disease Of Brain,Postencephalitic Parkinson Disease,Klippel-Feil Syndrome 1, Autosomal Dominant,Autosomal Dominant Cerebellar Ataxia,Disease Of Mental Health,Gaucher Disease, Type I,Toxic Encephalopathy,Failure Of Tooth Eruption, Primary,Rheumatoid Arthritis,Dementia, Lewy Body,Ophthalmomyiasis,Inflammatory Bowel Disease,Gerstmann-Straussler Disease,Parkinson Disease 21,Kufor-Rakeb Syndrome,Leprosy 3,Parkinson Disease 10,Parkinson Disease 8, Autosomal Dominant,Alzheimer Disease 8,Aphasia,Multiple System Atrophy 1,Color Agnosia,Mitochondrial Complex I Deficiency, Nuclear Type 1,Early-Onset Parkinson'S Disease,Parkinson Disease 2, Autosomal Recessive Juvenile,Frontotemporal Dementia,3-Methylglutaconic Aciduria, Type Iii,Parkinson Disease 15, Autosomal Recessive Early-Onset |
6dlo_b | Q5S007 | ENSG00000188906 | LRRK2 | 97.50 | 3.70E-08 | 5.40E-12 | 81.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YPR085C | ASA1 | SGDID:S000006289 | SNRPD3 |
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) |
Homo sapiens | Connective Tissue Disease,Spinal Muscular Atrophy,Muscular Atrophy,Lupus Erythematosus,Mixed Connective Tissue Disease,Systemic Lupus Erythematosus |
6qdv_n | P62318 | ENSG00000100028 | SNRPD3 | 97.00 | 5.30E-07 | 8.00E-11 | 69.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | GNB1 |
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) |
Bos taurus | 1tbg_c | P62871 | 97.20 | 2.80E-07 | 4.30E-11 | 72.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | Gnb5 |
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5) |
Mus musculus | 2pbi_d | P62881 | 97.20 | 2.80E-07 | 4.30E-11 | 73.60 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | RAE1 MRNP41 |
mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) |
Homo sapiens | Anterior Horn Cell Disease,Vulto-Van Silfhout-De Vries Syndrome,Autosomal Dominant Non-Syndromic Intellectual Disability,Lethal Congenital Contracture Syndrome 1,Lethal Congenital Contracture Syndrome |
3mmy_g | P78406 | ENSG00000101146 | RAE1 | 96.90 | 9.30E-07 | 1.40E-10 | 70.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | arc1 sop2 SPBC14C8.06 |
Actin-related protein 2/3 complex subunit 1 (Arp2/3 complex 41 kDa subunit) (p41-ARC) |
Schizosaccharomyces pombe | 3dwl_c | P78774 | 97.00 | 5.10E-07 | 7.90E-11 | 71.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SKI8 REC103 YGL213C |
Antiviral protein SKI8 (Superkiller protein 8) |
Saccharomyces cerevisiae | 5mc6_j | Q02793 | 97.10 | 4.80E-07 | 7.40E-11 | 72.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | UTP15 YMR093W YM9582.18 |
U3 small nucleolar RNA-associated protein 15 (U3 snoRNA-associated protein 15) (U three protein 15) (U3 protein 15 required for transcription) (t-UTP15) |
Saccharomyces cerevisiae | 5wlc_lj | Q04305 | 97.00 | 6.20E-07 | 8.50E-11 | 79.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SEC13 ANU3 YLR208W L8167.4 |
Protein transport protein SEC13 |
Saccharomyces cerevisiae | 2pm7_d | Q04491 | 97.20 | 2.30E-07 | 3.50E-11 | 71.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | Tc00.1047053511211.120 Tc00.1047053511211.130 |
Tc00.1047053511211.120 Tc00.1047053511211.130 |
Trypanosoma cruzi | 5opt_p | Q4DTN2 | 96.90 | 8.70E-07 | 1.40E-10 | 68.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SNRPD2 SNRPD1 |
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2) |
Homo sapiens | Spinal Muscular Atrophy |
6qdv_j | P62316 | ENSG00000125743 | SNRPD2 | 97.30 | 1.90E-07 | 2.70E-11 | 75.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | HSV2 KLLA0E15972g |
SVP1-like protein 2 |
Kluyveromyces lactis | 4av8_a | Q6CN23 | 96.90 | 8.90E-07 | 1.30E-10 | 70.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | RFWD3 RNF201 |
E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201) |
2.3.2.27 | Homo sapiens | Fanconi Anemia, Complementation Group V,Fanconi Anemia, Complementation Group R,Fanconi Anemia, Complementation Group U,Fanconi Anemia, Complementation Group A,Fanconi Anemia, Complementation Group W,Colon Lymphoma |
6cvz_a | Q6PCD5 | ENSG00000168411 | RFWD3 | 97.10 | 4.70E-07 | 7.10E-11 | 71.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YPR085C | ASA1 | SGDID:S000006289 | TaGB1 |
TaGB1 |
Triticum aestivum | 4v7e_bg | Q8LNY6 | 97.10 | 3.50E-07 | 5.40E-11 | 72.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SEH1L SEC13L SEH1 |
Nucleoporin SEH1 (GATOR complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein) |
Homo sapiens | Nonsyndromic Congenital Nail Disorder,Nemaline Myopathy 1,Achalasia-Addisonianism-Alacrima Syndrome,Nail Disorder, Nonsyndromic Congenital, 4 |
5a9q_p | Q96EE3 | ENSG00000085415 | SEH1L | 97.00 | 6.80E-07 | 1.00E-10 | 70.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | WDR92 |
WD repeat-containing protein 92 (WD repeat-containing protein Monad) |
Homo sapiens | 3i2n_a | Q96MX6 | ENSG00000243667 | WDR92 | 97.00 | 6.30E-07 | 9.90E-11 | 70.00 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YPR085C | ASA1 | SGDID:S000006289 | SPBPJ4664.04 |
Putative coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) |
Schizosaccharomyces pombe | 4j87_a | Q96WV5 | 97.30 | 1.70E-07 | 2.70E-11 | 72.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | Guanine nucleotide-binding protein subunit beta-like protein |
Guanine nucleotide-binding protein subunit beta-like protein |
Leishmania donovani | 5t2a_7 | Q9BIJ5 | 97.30 | 1.70E-07 | 2.70E-11 | 72.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | PREB SEC12 |
Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12) |
Homo sapiens | Hyperpigmentation With Or Without Hypopigmentation, Familial Progressive,Craniolenticulosutural Dysplasia |
5tf2_a | Q9HCU5 | ENSG00000138073 | PREB | 97.10 | 5.20E-07 | 7.70E-11 | 74.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | DCAF1 KIAA0800 RIP VPRBP |
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein) |
2.7.11.1 | Homo sapiens | Intraorbital Meningioma,Spinal Canal Intradural Extramedullary Neoplasm,Neurilemmomatosis,Aicardi-Goutieres Syndrome,Meningioma, Familial |
4cc9_a | Q9Y4B6 | 97.00 | 5.70E-07 | 7.90E-11 | 75.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YPR085C | ASA1 | SGDID:S000006289 | par-1 pan2 NCU04792 NCU10733 |
PAN2-PAN3 deadenylation complex catalytic subunit pan2 (EC 3.1.13.4) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2) |
3.1.13.4 | Neurospora crassa | 4czv_a | P0C581 | 97.10 | 3.30E-07 | 4.90E-11 | 72.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YPR085C | ASA1 | SGDID:S000006289 | TVAG_151920 |
TVAG_151920 |
Trichomonas vaginalis | 5xyi_g | A2ELV7 | 96.90 | 8.80E-07 | 1.40E-10 | 69.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | PAC1 LIS1 SCY_5321 |
Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog) |
Saccharomyces cerevisiae | 5vh9_b | A6ZPA6 | 97.10 | 4.80E-07 | 7.30E-11 | 71.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | CTHT_0055700 |
Ribosome assembly protein 4 (Notchless protein homolog 1) (Ribosome biogenesis factor RSA4) |
Chaetomium thermophilum | 4wjs_a | G0SC29 | 97.20 | 2.90E-07 | 4.40E-11 | 76.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | WD_REPEATS_REGION domain-containing protein |
WD_REPEATS_REGION domain-containing protein |
Oryctolagus cuniculus | 3jah_gg | G1SJB4 | 97.00 | 5.90E-07 | 9.00E-11 | 69.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | S10_plectin domain-containing protein |
S10_plectin domain-containing protein |
Oryctolagus cuniculus | 5k0y_t | G1T168 | 97.40 | 8.00E-08 | 1.20E-11 | 74.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | PLRG1 |
Pleiotropic regulator 1 |
Homo sapiens | Poikiloderma With Neutropenia,Cardiac Valvular Dysplasia, X-Linked |
4yvd_a | O43660 | ENSG00000171566 | PLRG1 | 97.10 | 3.70E-07 | 5.50E-11 | 73.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | RRP9 RNU3IP2 U355K |
U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K) |
Homo sapiens | 4j0w_a | O43818 | ENSG00000114767 | RRP9 | 97.10 | 3.80E-07 | 5.80E-11 | 71.90 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YPR085C | ASA1 | SGDID:S000006289 | WDHD1 AND1 |
WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) |
Homo sapiens | Cornelia De Lange Syndrome,Warsaw Breakage Syndrome |
5gva_a | O75717 | ENSG00000198554 | WDHD1 | 97.00 | 7.40E-07 | 1.10E-10 | 70.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | CIAO1 CIA1 WDR39 |
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39) |
Homo sapiens | Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 6,Xeroderma Pigmentosum, Variant Type,Alkhurma Hemorrhagic Fever |
3fm0_a | O76071 | ENSG00000144021 | CIAO1 | 97.00 | 5.90E-07 | 9.00E-11 | 70.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | TUP1 AAR1 AER2 AMM1 CYC9 FLK1 SFL2 UMR7 YCR084C YCR84C |
General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2) |
Saccharomyces cerevisiae | 1erj_a | P16649 | 97.70 | 1.80E-08 | 2.50E-12 | 85.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | RSA4 YCR072C YCR72C |
Ribosome assembly protein 4 (Notchless protein homolog 1) (Ribosome biogenesis factor RSA4) |
Saccharomyces cerevisiae | 4wjv_d | P25382 | 97.60 | 2.50E-08 | 3.80E-12 | 79.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SQT1 YIR012W YIB12W |
Ribosome assembly protein SQT1 |
Saccharomyces cerevisiae | 4zox_a | P35184 | 97.30 | 1.30E-07 | 2.00E-11 | 75.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SWD1 CPS50 SAF49 YAR003W FUN16 |
COMPASS component SWD1 (Complex proteins associated with SET1 protein SWD1) (Set1C component SWD1) |
Saccharomyces cerevisiae | 6bx3_b | P39706 | 96.90 | 9.20E-07 | 1.40E-10 | 72.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | TIF34 YMR146C YM9375.16C |
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 39 kDa subunit) (eIF-3 39 kDa subunit) (eIF3 p39) |
Saccharomyces cerevisiae | 5a5u_i | P40217 | 97.40 | 8.90E-08 | 1.40E-11 | 75.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SEC27 YGL137W G2827 |
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) |
Saccharomyces cerevisiae | 2yno_b | P41811 | 97.20 | 2.10E-07 | 3.00E-11 | 75.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | ELP2 TOT2 YGR200C G7725 |
Elongator complex protein 2 (Gamma-toxin target 2) |
Saccharomyces cerevisiae | 5m2n_a | P42935 | 97.20 | 2.90E-07 | 4.30E-11 | 82.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPR085C | ASA1 | SGDID:S000006289 | SEC13 D3S1231E SEC13A SEC13L1 SEC13R |
Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) |
Homo sapiens | Anemia, Congenital Dyserythropoietic, Type Ii,Chylomicron Retention Disease,Craniolenticulosutural Dysplasia |
3bg1_a | P55735 | ENSG00000157020 | SEC13 | 97.00 | 5.30E-07 | 8.30E-11 | 69.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | WDR5 BIG3 |
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) |
Homo sapiens | Kleefstra Syndrome,Kabuki Syndrome 1 |
6e1z_a | P61964 | ENSG00000196363 | WDR5 | 96.90 | 9.20E-07 | 1.40E-10 | 68.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPR085C | ASA1 | SGDID:S000006289 | SNRPE |
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE) |
Homo sapiens | Hypotrichosis,Spinal Muscular Atrophy,Hypotrichosis 11,Hypotrichosis Simplex,Hypotrichosis 8,Hypotrichosis 7,Hypotrichosis 4,Systemic Lupus Erythematosus,Hypotrichosis 6,Microcephalic Osteodysplastic Primordial Dwarfism, Type I |
6id1_e | P62304 | ENSG00000182004 | SNRPE | 97.00 | 5.40E-07 | 8.00E-11 | 72.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |