Sphingolipids in Health and Disease

Sphingolipids in Health and Disease

Our laboratory works on sphingolipids, important membrane components. We focus on two main areas: (i) sphingolipid synthesis and signaling, particularly of ceramide, and (ii) sphingolipid storage diseases, with an emphasis on mechanistic understanding of disease pathology and also on novel therapeutic approaches.

Sphingolipids in Health and Disease Picture No. 1
Ceramide synthesis mediated by CerS proteins
Sphingolipids in Health and Disease Picture No. 2
Pathophysiology of sphingolipid storage diseases
Sphingolipids in Health and Disease Picture No. 3
Sphingolipids in human diseases