Dr. Benjamin Dubreuil
I focused my work on the principles of proteome organization and evolution. My goal is to decipher the evolutionary forces that shape the cellular interior by analyzing the interplay between cellular abundance, biophysical features, and molecular evolution of proteins. Also, I develop tools for image analysis (www.yeastrgb.org, customs JS/FiJi scripts) to probe subcellular organization using fluorescence microscopy.
Dr. Saurav Mallik
I obtained my Ph.D. in 2019, from the University of Calcutta, where I investigated how the evolutionary trajectories of self-assembling molecular machines harbor the imprints of their assembly pathways. My postdoctoral work focuses on the evolution of protein oligomeric states in the face of genome expansion. Intriguingly, extant prokaryotes and eukaryotes harbor homomer- and heteromer-rich proteomes. I particularly aim to understand how and why did this paradigm shift in protein oligomeric state took place.
I'm investigating the interplay between agglomeration and cellular functions.