Group Members

I focused my work on the principles of proteome organization and evolution. My goal is to decipher the evolutionary forces that shape the cellular interior by analyzing the interplay between cellular abundance, biophysical features, and molecular evolution of proteins. Also, I develop tools for image analysis (www.yeastrgb.org, customs JS/FiJi scripts) to probe subcellular organization using fluorescence microscopy.

I'm using synthetic biology to uncover elementary principles of in vivo phase separation.

I obtained my Ph.D. in 2019, from the University of Calcutta, where I investigated how the evolutionary trajectories of self-assembling molecular machines harbor the imprints of their assembly pathways. My postdoctoral work focuses on the evolution of protein oligomeric states in the face of genome expansion. Intriguingly, extant prokaryotes and eukaryotes harbor homomer- and heteromer-rich proteomes. I particularly aim to understand how and why did this paradigm shift in protein oligomeric state took place.

I received my Ph.D. in 2019 from Paris Sud University. Based on protein structure analyses, I explored the interplay between the physico-chemistry of protein surface, functional, and non-functional interactions. I continue to study protein interactions and I am developing an approach to infer quantitive data on protein interactions in yeast.

I'm investigating the interplay between agglomeration and cellular functions.

I study sequence-dependance and specificity in interactions of phase-separating intrinsically-disordered proteins