Publications

2019

  1. Eliyahu E., Tirosh O., Dobesova M., Nachshon A., Schwartz M. & Stern-Ginossar N. (2019). Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation.  Journal of Virology. 93:(19)  Abstract
  2. Schwartz M. & Stern-Ginossar N. (2019). The Transcriptome of Latent Human Cytomegalovirus.  Journal of Virology. 93:(11)  Abstract
  3. Malakar P., Stein I., Saragovi A., Winkler R., Stern-Ginossar N., Berger M., Pikarsky E. & Karni R. (2019). Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2.  Cancer Research. 79:(10)2480-2493.  Abstract

2018

  1. Mizrahi O., Nachshon A., Shitrit A., Gelbart I. A., Dobesova M., Brenner S., Kahana C. & Stern-Ginossar N. (2018). Virus-Induced Changes in mRNA Secondary Structure Uncover cis-Regulatory Elements that Directly Control Gene Expression.  Molecular Cell. 72:(5)862-874.  Abstract
  2. Winkler R., Gillis E., Lasman L., Safra M., Geula S., Soyris C., Nachshon A., Tai-Schmiedel J., Friedman N., Le-Trilling V. T. K., Trilling M., Mandelboim M., Hanna J. H., Schwartz S. & Stern-Ginossar N. (2018). m6A modification controls the innate immune response to infection by targeting type I interferons.  Nature Immunology. 20:(2)173-182.  Abstract
  3. Lee J. S., Adler L., Karathia H., Carmel N., Rabinovich S., Auslander N., Keshet R., Stettner N., Silberman A., Agemy L., Helbling D., Eilam R., Sun Q., Brandis A., Malitsky S., Itkin M., Weiss H., Pinto S., Kalaora S., Levy R., Barnea E., Admon A., Dimmock D., Stern-Ginossar N., Scherz A., Nagamani S. C. S., Unda M., Wilson D. M., Elhasid R., Carracedo A., Samuels Y., Hannenhalli S., Ruppin E. & Erez A. (2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.  Cell. 174:(6)1559-1570.e22.  Abstract
  4. Stern-Ginossar N., Thompson S. R., Mathews M. B. & Mohr I. (2018). Translational Control in Virus-Infected Cells.  Cold Spring Harbor perspectives in biology. 11:(3)  Abstract
  5. Finkel Y., Stern-Ginossar N. & Schwartz M. (2018). Viral Short ORFs and Their Possible Functions.  Proteomics. 18:(10)  Abstract
  6. Toledano T., Vitenshtein A., Stern-Ginossar N., Seidel E. & Mandelboim O. (2018). Decay of the Stress-Induced Ligand MICA Is Controlled by the Expression of an Alternative 3 ' Untranslated Region.  Journal of Immunology. 200:(8)2819-2825.  Abstract
  7. Jafarnejad S. M., Chapat C., Matta-Camacho E., Gelbart I. A., Hesketh G. G., Arguello M., Garzia A., Kim S., Attig J., Shapiro M., Morita M., Khoutorsky A., Alain T., Christos G. G., Stern-Ginossar N., Tuschl T., Gingras A., Duchaine T. F. & Sonenberg N. (2018). Translational control of ERK signaling through miRNA/4EHP-directed silencing.  eLife. 7.  Abstract
  8. Shnayder M., Nachshon A., Krishn B., Poole E., Boshkov A., Binyamin A., Maza I., Sinclair J., Schwartz M. & Stern-Ginossar N. (2018). Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing.  mBio. 9:(2)  Abstract

2017

  1. Safra M., Sas-Chen A., Nir R., Winkler R., Nachshon A., Bar-Yaacov D., Erlacher M., Rossmanith W., Stern-Ginossar N. & Schwartz S. (2017). The m(1)A landscape on cytosolic and mitochondrial mRNA at single-base resolution.  Nature. 551:(7679)251-255.  Abstract
  2. Solomon O., Di Segni A., Cesarkas K., Porath H. T., Marcu-Malina V., Mizrahi O., Stern-Ginossar N., Kol N., Farage-Barhom S., Glick-Saar E., Lerenthal Y., Levanon E. Y., Amariglio N., Unger R., Goldstein I., Eyal E. & Rechavi G. (2017). RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.  Nature Communications. 8.  Abstract
  3. Moor A. E., Golan M., Massasa E. E., Lemze D., Weizman T., Shenhav R., Baydatch S., Mizrahi O., Winkler R., Golani O., Stern-Ginossar N. & Itzkovitz S. (2017). Global mRNA polarization regulates translation efficiency in the intestinal epithelium.  Science. 357:(6357)1299-+.  Abstract
  4. Chapat C., Jafarnejad S. M., Matta-Camacho E., Hesketh G. G., Gelbart I. A., Attig J., Gkogkas C. G., Alain T., Stern-Ginossar N., Fabian M. R., Gingras A., Duchaine T. F. & Sonenberg N. (2017). Cap-binding protein 4EHP effects translation silencing by microRNAs.  Proceedings of the National Academy of Sciences of the United States of America. 114:(21)5425-5430.

2016

  1. Bercovich-Kinori A., Tai J., Gelbart I. A., Shitrit A., Ben Moshe M. S., Drori Y., Itzkovitz S., Mandelboim M. & Stern-Ginossar N. (2016). A systematic view on influenza induced host shutoff.  eLife. 5.  Abstract
  2. Vitenshtein A., Weisblum Y., Hauka S., Halenius A., Oiknine-Djian E., Tsukerman P., Bauman Y., Bar-On Y., Stern-Ginossar N., Enk J., Ortenberg R., Tai J., Markel G., Blumberg R. S., Hengel H., Jonjic S., Wolf D. G., Adler H., Kammerer R. & Mandelboim O. (2016). CEACAM1-Mediated Inhibition of Virus Production.  Cell Reports. 15:(11)2331-2339.  Abstract
  3. Dar D., Shamir M., Mellin J. R., Koutero M., Stern-Ginossar N., Cossart P. & Sorek R. (2016). Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.  Science. 352:(6282)187-+.  Abstract
  4. Weingarten-Gabbay S., Elias-Kirma S., Nir R., Gritsenko A. A., Stern-Ginossar N., Yakhini Z., Weinberger A. & Segal E. (2016). Systematic discovery of cap-independent translation sequences in human and viral genomes.  Science. 351:(6270)240-U144.  Abstract
  5. Tichon A., Gil N., Lubelsky Y., Havkin Solomon S. T., Lemze D., Itzkovitz S., Stern-Ginossar N. & Ulitsky I. (2016). A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells.  Nature Communications. 7:12209.  Abstract

2015

  1. Fields A. P., Rodriguez E. H., Jovanovic M., Stern-Ginossar N., Haas B. J., Mertins P., Raychowdhury R., Hacohen N., Carr S. A., Ingolia N. T., Regev A. & Weissman J. S. (2015). A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation.  Molecular Cell. 60:(5)816-827.  Abstract
  2. Tirosh O., Cohen Y., Shitrit A., Shani O., Le-Trilling V. T. K., Trilling M., Friedlander G., Tanenbaum M. & Stern-Ginossar N. (2015). The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.  PLoS Pathogens. 11:(11)e1005288-e1005288.  Abstract
  3. Stern-Ginossar N. (2015). Decoding Viral Infection by Ribosome Profiling.  Journal of Virology. 89:(12)6164-6166.  Abstract
  4. Geula S., Moshitch-Moshkovitz S., Dominissini D., Mansour A. A., Kol N., Salmon-Divon M., Hershkovitz V., Peer E., Mor N., Manor Y. S., Ben-Haim M., Eyal E., Yunger S., Pinto Y., Jaitin D. A., Viukov S., Rais Y., Krupalnik V., Chomsky E., Zerbib M., Maza I., Rechavi Y., Massarwa R., Hanna S., Amit I., Levanon E. Y., Amariglio N., Stern-Ginossar N., Novershtern N., Rechavi G. & Hanna J. H. (2015). m(6)A mRNA methylation facilitates resolution of naive pluripotency toward differentiation.  Science. 347:(6225)1002-1006.  Abstract
  5. Stern-Ginossar N. & Ingolia N. T. (2015). Ribosome Profiling As A Tool To Decipher Viral Complexity.  . 335-349.  Abstract

2014

  1. Cohen Y. & Stern-Ginossar N. (2014). Manipulation of host pathways by human cytomegalovirus: insights from genome-wide studies.  Seminars in Immunopathology. 36:(6)651-658.  Abstract
  2. Ingolia N. T., Brar G. A., Stern-Ginossar N., Harris M. S., Talhouarne G. J. S., Jackson S. E., Wills M. R. & Weissman J. S. (2014). Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes.  Cell Reports. 8:(5)1365-1379.  Abstract
  3. Tsukerman P., Stern-Ginossar N., Yamin R., Ophir Y., Miller A., Stanietsky N. & Mandelboim O. (2014). Expansion of CD16 positive and negative human NK cells in response to tumor stimulation.  European Journal of Immunology. 44:(5)1517-1525.  Abstract
  4. Arias C., Weisburd B., Stern-Ginossar N., Mercier A., Madrid A. S., Bellare P., Holdorf M., Weissman J. S. & Ganem D. (2014). KSHV 2.0: A Comprehensive Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Genome Using NextGeneration Sequencing Reveals Novel Genomic and Functional Features.  PLoS Pathogens. 10:(1)  Abstract

2013

  1. Gilbert L. A., Larson M. H., Morsut L., Liu Z., Brar G. A., Torres S. E., Stern-Ginossar N., Brandman O., Whitehead E. H., Doudna J. A., Lim W. A., Weissman J. S. & Qi L. S. (2013). CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes.  Cell. 154:(2)442-451.  Abstract

2012

  1. Tsukerman P., Stern-Ginossar N., Gur C., Glasner A., Nachmani D., Bauman Y., Yamin R., Vitenshtein A., Stanietsky N., Bar-Mag T., Lankry D. & Mandelboim O. (2012). MiR-10b Downregulates the Stress-Induced Cell Surface Molecule MICB, a Critical Ligand for Cancer Cell Recognition by Natural Killer Cells.  Cancer Research. 72:(21)5463-5472.  Abstract
  2. Stern-Ginossar N., Weisburd B., Michalski A., Vu Thuy Khanh Le, Hein M. Y., Huang S., Ma M., Shen B., Qian S., Hengel H., Mann M., Ingolia N. T. & Weissman J. S. (2012). Decoding Human Cytomegalovirus.  Science. 338:(6110)1088-1093.  Abstract

2011

  1. Bauman Y., Nachmani D., Vitenshtein A., Tsukerman P., Drayman N., Stern-Ginossar N., Lankry D., Gruda R. & Mandelboim O. (2011). An Identical miRNA of the Human JC and BK Polyoma Viruses Targets the Stress-Induced Ligand ULBP3 to Escape Immune Elimination.  Cell Host and Microbe. 9:(2)93-102.  Abstract

2010

  1. Gur C., Porgador A., Elboim M., Gazit R., Mizrahi S., Stern-Ginossar N., Achdout H., Ghadially H., Dor Y., Nir T., Doviner V., Hershkovitz O., Mendelson M., Naparstek Y. & Mandelboim O. (2010). The activating receptor NKp46 is essential for the development of type 1 diabetes.  Nature Immunology. 11:(2)121-U37.  Abstract
  2. Manaster I., Gazit R., Goldman-Wohl D., Stern-Ginossar N., Mizrahi S., Yagel S. & Mandelboim O. (2010). Notch activation enhances IFN gamma secretion by human peripheral blood and decidual NK cells.  Journal of Reproductive Immunology. 84:(1)1-7.  Abstract

2009

  1. Stern-Ginossar N., Saleh N., Goldberg M. D., Prichard M., Wolf D. G. & Mandelboim O. (2009). Analysis of Human Cytomegalovirus-Encoded MicroRNA Activity during Infection.  Journal of Virology. 83:(20)10684-10693.  Abstract
  2. Stanietsky N., Simic H., Arapovic J., Toporik A., Levy O., Novik A., Levine Z., Beiman M., Dassa L., Achdout H., Stern-Ginossar N., Tsukerman P., Jonjic S. & Mandelboim O. (2009). The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity.  Proceedings Of The National Academy Of Sciences Of The United States Of America-Biological Sciences. 106:(42)17858-17863.  Abstract
  3. Stern-Ginossar N. & Mandelboim O. (2009). An integrated view of the regulation of NKG2D ligands.  Immunology. 128:(1)1-6.  Abstract
  4. Nachmani D., Stern-Ginossar N., Sarid R. & Mandelboim O. (2009). Diverse Herpesvirus MicroRNAs Target the Stress-induced Immune Ligand MICB to Escape Recognition by Natural Killer Cells.  Cell Host and Microbe. 5:(4)376-385.  Abstract
  5. Stern-Ginossar N., Gur C., Biton M., Horwitz E., Elboim M., Stanietsky N., Mandelboim M., Mandelboim O., Kaiser B. K., Yim D., Chow I. T., Gonzalez S., Dai Z., Mann H. H., Strong R. K., Groh V., Spies T., Cosman D., Mullberg J., Sutherland C. L., Chin W., Armitage R., Fanslow W., Kubin M. & Chalupny N. J. (2009). New twist on the regulation of NKG2D ligand expression (vol 206, pg 265, 2009).  Journal of Experimental Medicine. 206:(3)721-721.

2008

  1. Stern-Ginossar N., Gur C., Biton M., Horwitz E., Elboim M., Stanietsky N., Mandelboim M. & Mandelboim O. (2008). Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D.  Nature Immunology. 9:(9)1065-1073.  Abstract
  2. Manaster I., Mizrahi S., Goldman-Wohl D., Sela H. Y., Stern-Ginossar N., Lankry D., Gruda R., Hurwitz A., Bdolah Y., Haimov-Kochman R., Yagel S. & Mandelboim O. (2008). Endometrial NK cells are special immature cells that await pregnancy.  Journal of Immunology. 181:(3)1869-1876.  Abstract

2007

  1. Stern-Ginossar N., Nedvetzki S., Markel G., Gazit R., Betser-Cohen G., Achdout H., Aker M., Blumberg R. S., Davis D. M., Appelmelk B. & Mandelboim O. (2007). Intercellular transfer of carcinoembryonic antigen from tumor cells to NK cells.  Journal of Immunology. 179:(7)4424-4434.  Abstract
  2. Gruda R., Achdout H., Stern-Ginossar N., Gazit R., Betser-Cohen G., Manaster I., Katz G., Gonen-Gross T., Tirosh B. & Mandelboim O. (2007). Intracellular cysteine residues in the tail of MHC class I proteins are crucial for extracellular recognition by leukocyte Ig-like receptor 1.  Journal of Immunology. 179:(6)3655-3661.  Abstract
  3. Stern-Ginossar N., Elefant N., Zimmermann A., Wolf D. G., Saleh N., Biton M., Horwitz E., Prokocimer Z., Prichard M., Hahn G., Goldman-Wohl D., Greenfield C., Yagel S., Hengel H., Altuvia Y., Margalit H. & Mandelboim O. (2007). Host immune system gene targeting by a viral miRNA.  Science. 317:(5836)376-381.  Abstract
  4. Stern-Ginossar N. & Mandelboim O. (2007). Control LPS or get killed.  Blood. 109:(9)3614-3615.