RNA biology and membraneless organelles
APEX proximity labeling, proteomics and transcriptomics to characterize membraneless organelles and aberrant phase separation in neurodegeneration.
Research
Computational genetics of neurodegeneration
Computational methods to explore ALS non-coding genetics, using whole-genome sequencing and biofluid-based biomarker development.
Non-coding RNA tissue functions
Principles of miRNA-based commitment to a specific fate in stem cells and acquisition of a robust developmental outcomes, including in the regenerating pancreas.