RNA biology and membraneless organelles
APEX proximity labeling, proteomics and transcriptomics to characterize membraneless organelles and aberrant phase separation in neurodegeneration.
APEX proximity labeling, proteomics and transcriptomics to characterize membraneless organelles and aberrant phase separation in neurodegeneration.
Computational methods to explore ALS non-coding genetics, using whole-genome sequencing and biofluid-based biomarker development.
Principles of miRNA-based commitment to a specific fate in stem cells and acquisition of a robust developmental outcomes, including in the regenerating pancreas.