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Recent
References
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Mandelbaum AD, Melkman-Zehavi T, Oren R, Kredo-Russo S, Nir T, Dor Y, Hornstein E. Dysregulation of dicer1 in Beta cells impairs islet architecture and glucose metabolism. Exp Diabetes Res. 2012;2012:470302. Epub 2012 Sep 6.
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Kredo-Russo S., Mandelbaum AD., Ness A. , Alon I., Lennox KA., Behlke MA., Hornstein E. Pancreas enriched miRNA refines endocrine cell differentiation. Development 139, (2012) doi:10.1242/dev.080127.
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Barad O., Mann M., Chapnik E., Shenoy A., Blelloch R., Barkai N., Hornstein E. Efficiency and specificity in microRNA bioprocessing. Nature Structural & Molecular Biology. 2012 May 13.
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Hornstein E. Preface: miRNAs in Development. Curr Top Dev Biol. 2012 ;99:xi-xii. PMID: 22365742
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Kredo-Russo S., Ness A., Mandelbaum AD., Walker M., and Hornstein E. Regulation of pancreatic microRNA-7 expression. Experimental Diabetes Research. 2012 In press.
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Chapnik E., Sasson V., Blelloch R. and Hornstein E. Dgcr8 controls neural crest cells survival in cardiovascular development. Dev Biol. 2011 1;362(1):50-6. doi: 10.1016
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Ben Gradus, Ilana Alon, Eran Hornstein. miRNAs control tracheal chondrocyte differentiation. Dev Biol. 2011 ;360(1):58-65.
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Kredo-Russo S. Hornstein E. MicroRNA Knock Down by Cholesterol-Conjugated Antisense Oligos in Mouse Organ Culture. Methods Mol Biol. 2011;732:89-97.
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Haramati S., Navon I., Issler O, Ezra-Nevo G., Gil S., Zwang R., Hornstein E. & Chen. A.
microRNA as repressors of stress induced anxiety: the case of amygdalar miR-34
J Neurosci. 2011 ;31(40):14191-203.PDF
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Sudhir Gopal Tattikota and Matthew N Poy.
Re-dicing the pancreatic b-cell: do microRNAs define cellular identity?
The EMBO Journal (2011) 30, 797–799. doi:10.1038/emboj.2011.31PDF
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Melkman-Zehavi T, Oren R, Kredo-Russo S, Shapira T, Mandelbaum AD, Rivkin N, Nir T, Lennox KA, Behlke MA, Dor Y, Hornstein E.
miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors.
EMBO J. 2011. 2;30(5):835-45. PDF
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Barad O, Hornstein E, Barkai N. Robust selection of sensory organ precursors by the Notch-Delta pathway. Curr Opin Cell Biol. 2011 ;23(6):663-7.
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Goljanek-Whysall K, Sweetman D, Abu-Elmagd M, Chapnik E, Dalmay T, Hornstein E, Mu"nsterberg A.
MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis.
Proc Natl Acad Sci U S A. 2011. PDF
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Lerman G, Avivi C, Mardoukh C, Barzilai A, Tessone A, Gradus B, Pavlotsky F, Barshack I, Polak-Charcon S, Orenstein A, Hornstein E, Sidi Y, Avni D.
miRNA Expression in Psoriatic Skin: Reciprocal Regulation of hsa-miR-99a and IGF-1R.
PLoS One. 2011 ;6(6):e20916.PDF
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Biton M, Levin A, Slyper M, Alkalay I, Horwitz E, Mor H, Kredo-Russo S, Avnit-Sagi T, Cojocaru G, Zreik F, Bentwich Z, Poy MN, Artis D, Walker MD, Hornstein E, Pikarsky E, Ben-Neriah Y.
Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.
Nat Immunol. 2011 ;12(3):239-46.PDF
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Afek Y, Alon N, Barad O, Hornstein E, Barkai N, Bar-Joseph Z.
A biological solution to a fundamental distributed computing problem.
Science. 2011 Jan. 331(6014):183.PDF
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Hornstein E.
miRNA activity directs stem cell commitment to a particular fate.
Cell Cycle. 2010 Oct. 9(20):4041-2.PDF
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Mann M, Barad O, Agami R, Geiger B, Hornstein E.
miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate.
Proc Natl Acad Sci U S A. 2010 Aug. ;107(36):15804-9.PDF
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Haramati S, Chapnik E, Sztainberg H, Eilam-Altstadter R, Zwang R, Gershoni N, McGlinn E, Heiser WP, Wills AM, Wirguin I, Misawa H, Rubin LL, Tabin C, Brown Jr. RH, Chen A, Hornstein E.
miRNA malfunction causes spinal motor neuron disease.
Proc Natl Acad Sci U S A. 2010 ;107(29): 13111-6. PDF
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Gradus B. Hornstein E. microRNA role in bone development. Topics in Bone Biology. Ed. C. Farach-Carson and F. Bronner. Spring UK. 2010
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Barad O, Rosin D, Hornstein E, Barkai N. Error minimization in the Notch-Delta lateral inhibition system. Sci Signal. 2010 Jul. 6;3(129):ra51.
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Shomron N, Golan D, Hornstein E, An evolutionary perspective of animal microRNAs and their targets.
J Biomed Biotechnol. 2009.594738.
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Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB. MicroRNAs are essential for development and function of inner ear hair cells in vertebrates.
Proc Natl Acad Sci U S A. 2009 06(19):7915-20.
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Avnit-Sagi T, Kantorovich L, Kredo-Russo S, Hornstein E, Walker MD.
The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas.
PLoS ONE. 2009;4(4):e5033.
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Life Sciences Open day 2008 - miRNA role in development
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Nielsen C. Shomron N. Sandberg R, Hornstein E, Kitzman J, Burge CB. Determinants of Targeting by Endogenous and Exogenous MicroRNAs and siRNAs.
RNA. 2007 13(11):1894-910.
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Hornstein E, Shomron S. Canalization of Development by
miRNAs
Nature Genetics. 2006 Jun 30;38:Suppl 1:S20-S24. PDF
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Life Sciences Open day 2006 - miRNA role in development PDF
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Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT,
Baskerville S, Bartel DP, Tabin CJ The microRNA miR-196 acts
upstream of Hoxb8 and Shh in limb development.
Nature. 2005 Dec
1;438(7068):671-4. PDF
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Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ.
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
Proc Natl Acad Sci U S A. 2005
Aug 2;102(31):10898-903. PDF
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Hornstein E, Tabin CJ.
Developmental biology: asymmetrical threat averted.
Nature. 2005 May 12;435(7039):155-6 PDF
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Hornstein E, Benvenisty N.
The "brainy side" of human embryonic stem cells.
J Neurosci Res. 2004 Apr 15;76(2):169-73. PDF
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