Tuesday,
April 17, 2012 - 12:30
Schmidt Lecture Hall
Prof. Joshua Gordon
Dept of Psychiatry, Columbia University and The New York State Psychiatric Institute
The hippocampus and prefrontal cortex, two brain regions frequently implicated in psychiatric illness, must cooperate to regulate both cognitive and emotional behaviors. We and others have shown that these two brain regions synchronize their activity during behavior. I will discuss the dynamics of this synchrony during working memory and anxiety, how it shapes neuronal responses in the prefrontal cortex, and how it is altered by genetic manipulations of relevance to psychiatric disease.