Regulation by non coding RNAs including microRNAs (miRNA) is the most abundant mode of post-transcriptional regulation, affecting roughly every other gene. This means that these non coding RNA molecules take part in practically all cellular processes, whether in health or disease.
In the Weizmann Institute of Science there is a well-established community of researchers, actively involved in diverse facets of miRNA research. This community includes specialized labs, for which miRNA biology is a central theme, as well as labs that study miRNA in the broader contexts of cell informatics, molecular biology, developmental biology and pathophysiology.
The concept underlying this webpage is to provide extra leverage towards uncovering many more facets of miRNA function in normal states and in diseases by the Weizmann strong multi-disciplinary team.
The Weizmann Institute of Science promotes miRNA research with enhanced accessibility to high-throughput acquisition of genomic data and provides substantial resources for biological gain-of-function and loss-of-function studies /in vivo/ and /in vitro/. Weizmann core facilities would enable the conduction of scientific projects
aimed at uncovering the basics of miRNA biology and shedding light on miRNA's role in human diseases such as diabetes mellitus, cancer, ALS and myelodysplastic syndrome.