Publications
Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D.
(2020).
Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.
Proceedings of the National Academy of Sciences of the United States of America.
117:(1)395-404.
Prabahar V., Afriat-Jurnou L., Paluy I., Peleg Y. & Noy D.
(2020).
New homologues of Brassicaceae water-soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution.
FEBS Journal.
287:(5)991-1004.
Suzumoto Y., Dym O., Roviello G. N., Worek F., Sussman J. L. & Manco G.
(2020).
Structural and functional characterization of new ssopox variant points to the dimer interface as a driver for the increase in promiscuous paraoxonase activity.
International Journal of Molecular Sciences.
21:(5)
Rosenthal M., Metzl-Raz E., Buergi J., Yifrach E., Drwesh L., Fadel A., Peleg Y., Rapaport D., Wilmanns M., Barkai N., Schuldiner M. & Zalckvar E.
(2020).
Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.
Proceedings of the National Academy of Sciences - PNAS.
117:(35)21432-21440.
Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J.
(2019).
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
PLoS Computational Biology.
15:(8)
Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D.
(2019).
Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.
ChemPhysChem.
20:(14)1860-1868.
Arafeh R., Di Pizio A., Elkahloun A. G., Dym O., Niv M. Y. & Samuels Y.
(2019).
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma.
Oncogene.
38:(13)2432-2434.
Novichkova D. A., Lushchekina S., Dym O., Masson P., Silman I. & Sussman J. L.
(2019).
The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability.
Chemico-Biological Interactions.
309.
Zahradnik J., Kolarova L., Peleg Y., Kolenko P., Svidenska S., Charnavets T., Unger T., Sussman J. L. & Schneider B.
(2019).
Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1.
FEBS Journal.
286:(19)3858-3873.
Netzer R., Listov D., Lipsh R., Dym O., Albeck S., Knop O., Kleanthous C. & Fleishman S. J.
(2018).
Ultrahigh specificity in a network of computationally designed protein-interaction pairs.
Nature Communications.
9:(1)
Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G.
(2018).
Manipulating the Folding Landscape of a Multi-Domain Protein.
Journal of Physical Chemistry B.
122:(49)11030-11038.
Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R.
(2018).
Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.
Nature Communications.
9:(1)
Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M.
(2018).
Rapid characterization of secreted recombinant proteins by native mass spectrometry.
Communications Biology.
1:(1)
Karniel A., Mrusek D., Steinchen W., Dym O., Bange G. & Bibi E.
(2018).
Co-translational folding intermediate dictates membrane targeting of the signal recognition particle-receptor.
Journal of Molecular Biology.
430:(11)1607-1620.
Bandyopadhyay B., Goldenzweig A., Unger T., Adato O., Fleishman S. J., Unger R. & Horovitz A.
(2017).
Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL.
Journal of Biological Chemistry.
292:(50)20583-20591.
Milrot E., Shimoni E., Dadosh T., Rechav K., Unger T., Van Etten E. J. L. & Minsky A.
(2017).
Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1.
PLoS Pathogens.
13:(8)
Cohen-Khait R., Dym O., Hamer-Rogotner S. & Schreiber G.
(2017).
Promiscuous Protein Binding as a Function of Protein Stability.
Structure (London, England : 1993).
25:(12)1867-1874.e3.
Dym O., Song W., Felder C., Roth E., Shnyrov V., Ashani Y., Xu Y., Joosten R. P., Weiner L., Sussman J. & Silman I.
(2016).
The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex.
Protein Science.
25:(6)1096-1114.
Sobolev V., Edelman M., Dym O., Unger T., Albeck S., Kirma M. & Galili G.
(2013).
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis.
Acta Crystallographica Section F-Structural Biology And Crystallization Communications.
69:(2)84-89.
Hama S., Soran H., Albeck S., Charlton-Menys V., Yadav R., Liu Y., France M., Tawfiq D. & Durrington P.
(2012).
High Paraoxonase-1 Hdl is More Effective Than Low Paraoxonase-1 Hdl in Impeding Ldl Oxidation in Vitro.
Atherosclerosis.
223:(2)529-529.
Carlessi R., Levin-Salomon V., Ciprut S., Bialik S., Berissi H., Albeck S., Peleg Y. & Kimchi A.
(2011).
GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.
EMBO Reports.
12:(9)917-923.
Karanicolas J., Com J. E., Chen I., Joachimiak L. A., Dym O., Peck S. H., Albeck S., Unger T., Hu W., Liu G., Delbecq S., Montelione G. T., Spiegel C. P., Liu D. R. & Baker D.
(2011).
A De Novo Protein Binding Pair By Computational Design and Directed Evolution.
Molecular Cell.
42:(2)250-260.
Unger T., Dym O., Albeck S., Jacobovitch Y., Bernehim R., Marom D., Pisanty O. & Breiman A.
(2010).
Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain.
Journal of Structural and Functional Genomics.
11:(2)113-23.
Sharabi O., Peleg Y., Mashiach E., Vardy E., Ashani Y., Simian I., Sussman J. L. & Shifman J. M.
(2009).
Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase.
Protein Engineering Design & Selection.
22:(10)641-648.
Liberman N., Dym O., Unger T., Albeck S., Peleg Y., Jacobovitch Y., Branzburg A., Eisenstein M., Marash L. & Kimchi A.
(2008).
The Crystal Structure of the C-Terminal DAP5/p97 Domain Sheds Light on the Molecular Basis for Its Processing by Caspase Cleavage.
Journal of Molecular Biology.
383:(3)539-548.
Dym O., Albeck S., Unger T., Jacobovitch J., Branzburg A., Michael Y., Frenkiel-Krispin D., Wolf S. G. & Elbaum M.
(2008).
Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.
Proceedings of the National Academy of Sciences of the United States of America.
105:(32)11170-11175.
Albeck S., Dym O., Unger T., Snapir Z., Bercovich Z. & Kahana C.
(2008).
Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function.
Protein Science.
17:(5)793-802.
Peleg Y. & Unger T.
(2008).
Application of High-Throughput Methodologies to the Expression of Recombinant Proteins in E. coli.
.
197-208.
Goihberg E., Dym O., Tel-Or S., Shimon L., Frolow F., Peretz M. & Burstein Y.
(2008).
Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.
Proteins-Structure Function And Bioinformatics.
72:(2)711-719.
Shao H., Revach M., Moshonov S., Tzuman Y., Gazit K., Albeck S., Unger T. & Dikstein R.
(2005).
Core promoter binding by histone-like TAF complexes.
Molecular and Cellular Biology.
25:(1)206-219.
Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A.
(2002).
Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.
Journal of Biological Chemistry.
277:(48)46304-46309.
Unger T., Oren Z. & Shai Y.
(2001).
The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: Implication to their mode of action.
Biochemistry.
40:(21)6388-6397.
Mor F., Boccaccio G. & Unger T.
(1998).
Expression of autoimmune disease-related antigens by cells of the immune system.
Journal of Neuroscience Research.
54:(2)254-262.
Tamary H., Fromovich Y., Shalmon L., Reich Z., Dym O., Lanir N., Brenner B., Paz M., Luder A., Blau O., Korostishevsky M., Zaizov R. & Seligsohn U.
(1996).
Ala244Val is a common, probably ancient mutation causing factor VII deficiency in Moroccan and Iranian Jews.
Thrombosis and Haemostasis.
76:(3)283-291.
Fiscella M., Zambrano N., Ullrich S. J., Unger T., Lin D., Cho B., Mercer W. E., Anderson C. W. & Appella E.
(1994).
The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.
Oncogene.
9:(11)3249-57.
Mietz J. A., Unger T., Huibregtse J. M. & Howley P. M.
(1992).
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.
EMBO Journal.
11:(13)5013-20.
Unger T., Nau M. M., Segal S. & Minna J. D.
(1992).
p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer.
EMBO Journal.
11:(4)1383-90.
Unger T. & Shaul Y.
(1990).
The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element.
EMBO Journal.
9:(6)1889-1895.
Erijman A., Dantes A., Bernheim R., Shifman J. M. & Peleg Y.
().
Transfer-PCR (TPCR): A highway for DNA cloning and protein engineering.
Journal of Structural Biology.
175:(2)171-177.
Aizenberg J., Albeck S., Weiner S. & Addadi L.
().
Crystal-protein interactions studied by overgrowth of calcite on biogenic skeletal elements.
Journal of Crystal Growth.
142:(1-2)156-164.
Berry I. M., Dym O., Esnouf R. M., Harlos K., Meged R., Perrakis A., Sussman J., Walter T. S., Wilson J. & Messerschmidt A.
().
SPINE high-throughput crystallization, crystal imaging and recognition techniques: Current state, performance analysis, new technologies and future aspects.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1137-1149.
Lahav-Mankovski N., Prasad P. K., Oppenheimer-Low N., Raviv G., Dadosh T., Unger T., Salame T. M., Motiei L. & Margulies D.
().
Decorating Bacteria with Self-Assembled Synthetic Receptors.
Nature Communications.
11:(1)
KolářOvá L., ZahradníK J., HuličIak M., Mikulecký P., Peleg Y., Shemesh M., Schreiber G. & Schneider B.
().
De novo developed protein binders mimicking Interferon lambda signaling.
FEBS Journal.
289:(9)2672-2684.
Goldenzweig A., Goldsmith M., Hill S. E., Gertman O., Laurino P., Ashani Y., Dym O., Unger T., Albeck S., Prilusky J., Lieberman R. L., Aharoni A., Silman I., Sussman J., Tawfik D. & Fleishman S. J.
().
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Molecular Cell.
63:(2)337-346.
Siton O., Ideses Y., Albeck S., Unger T., Bershadsky A. D., Gov N. S. & Bernheim-Groswasser A.
().
Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.
Current Biology.
21:(24)2092-2097.
Addadi L., Aizenberg J., Albeck S., Berman A., Leiserowitz L. & Weiner S.
().
Controlled occlusion of proteins: A tool for modulating the properties of skeletal elements.
Molecular Crystals and Liquid Crystals.
248:(1)185-198.
Peleg Y., Prabahar V., Bednarczyk D. & Unger T.
().
Harnessing the Profinity eXact™ System for Expression and Purification of Heterologous Proteins in E. coli.
.
33-43.
Dym O., Mevarech M. & Sussman J. L.
().
Structural features that stabilize halophilic malate dehydrogenase from an archaebacterium.
Science.
267:(5202)1344-1346.
Xu Y., Li M., Greenblatt H., Chen W., Paz A., Dym O., Peleg Y., Chen T., Shen X., He J., Jiang H., Silman I. & Sussman J.
().
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations.
Acta Crystallographica Section D: Biological Crystallography.
68:(1)13-25.
Franz F., Tapia-Rojo R., Winograd-Katz S., Boujemaa-Paterski R., Li W., Unger T., Albeck S., Aponte-Santamaria C., Garcia-Manyes S., Medalia O., Geiger B. & GräTer F.
().
Allosteric activation of vinculin by talin.
Nature Communications.
14:(1)
Aricescu A. R., Assenberg R., Bill R. M., Busso D., Chang V. T., Davis S. J., Dubrovsky A., Gustafsson L., Hedfalk K., Heinemann U., Jones I. M., Ksiazek D., Lang C., Maskos K., Messerschmidt A., Macieira S., Peleg Y., Perrakis A., Poterszman A., Schneider G., Sixma T. K., Sussman J., Sutton G., Tarboureich N., Zeev-Ben-Mordehai T. & Jones E. Y.
().
Eukaryotic expression: Developments for structural proteomics.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1114-1124.
Albeck S., Nordlund P. & Sussman J. L.
().
New trends in protein expression.
Journal of Structural Biology.
172:(1)1-2.
RöThlisberger D., Khersonsky O., Wollacott A. M., Jiang L., Dechancie J., Betker J., Gallaher J. L., Althoff E. A., Zanghellini A., Dym O., Albeck S., Houk K. N., Tawfik D. S. & Baker D.
().
Kemp elimination catalysts by computational enzyme design.
Nature.
453:(7192)190-195.
Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar Avihail A. A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., Amitai G. & Sorek R.
().
Communication between viruses guides lysis-lysogeny decisions.
Nature.
541:(7638)488-493.
Unger T. & Peleg Y.
().
Recombinant protein expression in the baculovirus-infected insect cell system.
.
187-199.
Cohen J., Unger T., Rechavi G., Canaani E. & Givol D.
().
Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas.
Nature.
306:(5945)797-799.
Tal L., Friedlander G., Gilboa N. S., Unger T., Gilad S. & Eshed Y.
().
Coordination of meristem doming and the floral transition by late termination, a kelch repeat protein.
Plant Cell.
29:(4)681-696.
Israeli H., Degtjarik O., Fierro F., Chunilal V., Gill A. K., Roth N. J., Botta J., Prabahar V., Peleg Y., Chan L. F., Ben-Zvi D., Mccormick P. J., Niv M. Y. & Shalev-Benami M.
().
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.
Science.
372:(6544)808-814.
Mishra N. K., Habeck M., Kirchner C., Haviv H., Peleg Y., Eisenstein M., Apell H. J. & Karlish S. J. D.
().
Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase.
Journal of Biological Chemistry.
290:(48)28746-28759.
Rozenberg A., Kaczmarczyk I., Matzov D., Vierock J., Nagata T., Sugiura M., Katayama K., Kawasaki Y., Konno M., Nagasaka Y., Aoyama M., Das I., Pahima E., Church J., Adam S., Borin V. A., Chazan A., Augustin S., Wietek J., Dine J., Peleg Y., Kawanabe A., Fujiwara Y., Yizhar O., Sheves M., Schapiro I., Furutani Y., Kandori H., Inoue K., Hegemann P., Beja O. & Shalev-Benami M.
().
Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels.
Nature Structural and Molecular Biology.
29:(6)592-603.
Bharat T. A. M., Zbaida D., Eisenstein M., Frankenstein Z., Mehlman T., Weiner L., Sorzano C. O. S., Barak Y., Albeck S., Briggs J. A. G., Wolf S. G. & Elbaum M.
().
Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA.
Structure.
21:(7)1158-1167.
Heyne M., Shirian J., Cohen I., Peleg Y., Radisky E. S., Papo N. & Shifman J. M.
().
Climbing up and down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes.
Journal of the American Chemical Society.
143:(41)17261-17275.
Unger T., Juven-Gershon T., Moallem E., Berger M., Sionov R., Lozano G., Oren M. & Haupt Y.
().
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
EMBO Journal.
18:(7)1805-1814.
Franz F., Tapia-Rojo R., Winograd-Katz S., Boujemaa-Paterski R., Li W., Unger T., Albeck S., Aponte-Santamaria C., Garcia-Manyes S., Medalia O., Geiger B. & GräTer F.
().
How talin allosterically activates vinculin.
BioRxiv.
Kahlon S., Shreibman D., Unger T., Ben-Yehuda D. & Elias S.
().
The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition.
Blood Cancer Journal.
8:(5)
Sen S., Bhowmik P., Tiwari S., Peleg Y. & Bandyopadhyay B.
().
Versatility of reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) from diagnosis of early pathological infection to mutation detection in organisms.
Molecular Biology Reports.
51:(1)
Mohan V., Gaffney J. P., Solomonov I., Levin M., Klepfish M., Akbareian S., GrüNwald B., Dym O., Eisenstein M., Yu K. H., Kelsen D. P., KrüGer A., Edwards D. R. & Sagi I.
().
Conformation-specific inhibitory anti-mmp-7 monoclonal antibody sensitizes pancreatic ductal adenocarcinoma cells to chemotherapeutic cell kill.
Cancers.
13:(7)
Halfin O., Avram L., Albeck S., Unger T., Motiei L. & Margulies D.
().
Unnatural Enzyme Activation by a Metal-Responsive Regulatory Protein.
Chemical Science.
15:(35)14209-14217.
Singh A., Erijman A., Noronha A., Kumar H., Peleg Y., Yarden Y. & Shifman J. M.
().
Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma.
Journal of Biological Chemistry.
297:(6)
Khersonsky O., Kiss G., RöThlisberger D., Dym O., Albeck S., Houk K. N., Baker D. & Tawfik D. S.
().
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.
Proceedings of the National Academy of Sciences of the United States of America.
109:(26)10358-10363.
Manicka S., Peleg Y., Unger T., Albeck S., Dym O., Greenblatt H. A., Bourenkov G., Lamzin V., Krishnaswamy S. & Sussman J.
().
Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12.
Proteins-Structure Function And Bioinformatics.
71:(4)2102-2108.
Allouche-Arnon H., Khersonsky O., Tirukoti N. D., Peleg Y., Dym O., Albeck S., Brandis A., Mehlman T., Avram L., Harris T., Yadav N. N., Fleishman S. J. & Bar-Shir A.
().
Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.
Nature Biotechnology.
40:(7)1143-1149.
Romier C., Ben Jelloul M., Albeck S., Buchwald G., Busso D., Celie P. H., Christodoulou E., De Marco V., Van Gerwen S., Knipscheer P., Lebbink J. H., Notenboom V., Poterszman A., Rochel N., Cohen S. X., Unger T., Sussman J. L., Moras D., Sixma T. K. & Perrakis A.
().
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: Experimental procedures, database tracking and case studies.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1232-1242.
Ben-Nissan G., Belov M. E., Morgenstern D., Levin Y., Dym O., Arkind G., Lipson G., Makarov A. A. & Sharon M.
().
Triple-Stage Mass Spectrometry Unravels the Heterogeneity of an Endogenous Protein Complex.
Analytical Chemistry.
89:(8)4708-4715.
Smock R. G., Yadid I., Dym O., Clarke J. & Tawfik D.
().
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints.
Cell.
164:(3)476-486.
Shemi A., Ben-Dor S., Rotkopf R., Dym O. & Vardi A.
().
Phylogeny and biogeography of the algal DMS-releasing enzyme in the global ocean.
ISME Communications.
3.
Yosef E., Katz A., Peleg Y., Mehlman T. & Karlish S. J.
().
Do Src kinase and caveolin interact directly with Na,K-ATPase?.
Journal of Biological Chemistry.
291:(22)11736-11750.
Lal M., Kesselman E., Wachtel E., Kleinerman O., Peleg Y., Albeck S., Majhi K., Sheves M. & Patchornik G.
().
His-tag based supramolecular biopolymerization.
Scientific Reports.
14.
Levi Y., Albeck S., Brack A., Weiner S. & Addadi L.
().
Control over aragonite crystal nucleation and growth: An in vitro study of biomineralization.
Chemistry-A European Journal.
4:(3)389-396.
Sela-Passwell N. A., Kikkeri R., Dym O., Rozenberg H., Margalit R., Arad-Yellin R., Eisenstein M., Brenner O., Shoham T., Danon T., Shanzer A. & Sagi I.
().
Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential.
Nature Medicine.
18:(1)143-147.
Albeck S., Alzari P., Andreini C., Banci L., Berry I. M., Bertini I., Cambillau C., Canard B., Carter L., Cohen S. X., Diprose J. M., Dym O., Esnouf R. M., Felder C., Ferron F., Guillemot F., Hamer R., Ben Jelloul J. M., Laskowski R. A., Laurent T., Longhi S., Lopez R., Luchinat C., Malet H., Mochel T., Morris R. J., Moulinier L., Oinn T., Pajon A., Peleg Y., Perrakis A., Poch O., Prilusky J., Rachedi A., Ripp R., Rosato A., Silman I., Stuart D. I., Sussman J., Thierry J. -., Thompson J. D., Thornton J. M., Unger T., Vaughan B., Vranken W., Watson J. D., Whamond G. & Henrick K.
().
SPINE bioinformatics and data-management aspects of high-throughput structural biology.
Acta Crystallographica Section D-Structural Biology.
62:(10)1184-1195.
Seal M., Jash C., Jacob R., Feintuch A., Harel Y., Albeck S., Unger T. & Goldfarb D.
().
Evolution of CPEB4 Dynamics across its Liquid-Liquid Phase Separation Transition.
Journal Of Physical Chemistry B.
125:(47)12947-12957.
Saikia C., Dym O., Altman-Gueta H., Gordon D., Reuveny E. & Karbat I.
().
A Molecular Lid Mechanism of K+ Channel Blocker Action Revealed by a Cone Peptide.
Journal of Molecular Biology.
433:(17)
Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. -., Burmeister W. P., Cambillau C., Canard B., Carrondo M., Coll M., Daenke S., Dym O., Egloff M. -., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q. & Manicka S. N.
().
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1196-1207.
Albeck S., Unger R. & Schreiber G.
().
Evaluation of direct and cooperative contributions towards the strength of buried hydrogen bonds and salt bridges.
Journal of Molecular Biology.
298:(3)503-520.
Scheerer D., Adkar B. V., Bhattacharyya S., Levy D., Iljina M., Riven I., Dym O., Haran G. & Shakhnovich E. I.
().
Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase.
Proceedings of the National Academy of Sciences of the United States of America.
120:(118)
Li M., Greenblatt H. M., Dym O., Albeck S., Pais A., Gunanathan C., Milstein D., Degani H. & Sussman J.
().
Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators.
Journal of Medicinal Chemistry.
54:(10)3575-3580.
Gurfinkel N., Unger T., Givol D. & Mushinski J. F.
().
Expression of the bcl2 gene in mouse B lymphocytic cell lines is differentiation stage specific.
European Journal of Immunology.
17:(4)567-570.
Unger T., Sionov R., Moallem E., Yee C., Howley P., Oren M. & Haupt Y.
().
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
Oncogene.
18:(21)3205-3212.
Vazana Y., Barak Y., Unger T., Peleg Y., Shamshoum M., Ben-Yehezkel T., Mazor Y., Shapiro E., Lamed R. & Bayer E.
().
A synthetic biology approach for evaluating the functional contribution of designer cellulosome components to deconstruction of cellulosic substrates.
Biotechnology for Biofuels.
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Chaturvedi A. K., Dym O., Levin Y. & Fluhr R.
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PGR5-LIKE PHOTOSYNTHETIC PHENOTYPE1A redox states alleviate photoinhibition during changes in light intensity.
Plant Physiology.
194:(2)1059-1074.
Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Nissan G. B., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J.
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Erratum: Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces (PLoS Computational Biology(2019)15: 8(e1007207)Doi: 10.1371/journal.pcbi.1007207).
PLoS Computational Biology.
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Wein T., Millman A., Lange K., Yirmiya E., Hadary R., Garb J., Melamed S., Amitai G., Dym O., Steinruecke F., Hill A. B., Kranzusch P. J. & Sorek R.
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CARD domains mediate anti-phage defence in bacterial gasdermin systems.
Nature.
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Adams E. M., Pezzotti S., Ahlers J., RüTtermann M., Levin M., Goldenzweig A., Peleg Y., Fleishman S. J., Sagi I. & Havenith M.
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Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction.
JACS Au.
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Control of aragonite or calcite polymorphism by mollusk shell macromolecules.
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Interactions of Various Skeletal Intracrystalline Components with Calcite Crystals.
Journal of the American Chemical Society.
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DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.
Nature Communications.
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Shraga A., Olshvang E., Davidzohn N., Khoshkenar P., Germain N., Shurrush K., Carvalho S., Avram L., Albeck S., Unger T., Lefker B., Subramanyam C., Hudkins R. L., Mitchell A., Shulman Z., Kinoshita T. & London N.
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Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.
Cell Chemical Biology.
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A single proline substitution is critical for the thermostabilization of Clostridium beijerinckii alcohol dehydrogenase.
Proteins-Structure Function And Bioinformatics.
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Separation, Immobilization, and Biocatalytic Utilization of Proteins by a Supramolecular Membrane.
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Khmelnitsky L., Milo A., Dym O. & Fass D.
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Diversity of CysD domains in gel-forming mucins.
FEBS Journal.
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Goihberg E., Peretz M., Tel-Or S., Dym O., Shimon L., Frolow F. & Burstein Y.
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Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms.
Biochemistry.
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Peri L., Matzov D., Huxley D. R., Rainish A., Fierro F., Sapir L., Pfeiffer T., Waterloo L., HüBner H., Peleg Y., Gmeiner P., Mccormick P. J., Weikert D., Niv M. Y. & Shalev-Benami M.
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A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCR.
Nature Communications.
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Fluorescent supramolecular fibers and sheets built from doubly hexa-His tagged mCherry proteins conjugated by divalent metal cations.
International Journal of Biological Macromolecules.
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Integration of bacterial lytic polysaccharide monooxygenases into designer cellulosomes promotes enhanced cellulose degradation.
Proceedings of the National Academy of Sciences of the United States of America.
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Three-dimensional structure determination of proteins related to human health in their functional context at the Israel Structural Proteomics Center (ISPC).
Acta Crystallographica Section D: Biological Crystallography.
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The human interferon receptor: NMR-based modeling, mapping of the IFN-α2 binding site, and observed ligand-induced tightening.
Biochemistry.
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The identification and characterization of an oxalyl-CoA synthetase from grass pea (Lathyrus sativus L.).
RSC Chemical Biology.
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Yeshaya N., Gupta P. K., Dym O., Morgenstern D., Major D. T. & Fass D.
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VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Protein Science.
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Ben-David M., Soskine M., Dubovetskyi A., Cherukuri K., Dym O., Sussman J. L., Liao Q., Szeler K., Kamerlin S. C. L. & Tawfik D. S.
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Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition.
Molecular Biology and Evolution.
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gUMI-BEAR, a modular, unsupervised population barcoding method to track variants and evolution at high resolution.
PLoS ONE.
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FXYD proteins stabilize Na,K-ATpase: Amplification of specific phosphatidylserine-protein interactions.
Journal of Biological Chemistry.
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Monitoring the Conformation of the Sba1/Hsp90 Complex in the Presence of Nucleotides with Mn(II)-Based Double ElectronElectron Resonance.
Journal of Physical Chemistry Letters.
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Jiang W., Wang X. W., Unger T., Forgues M., Kim J. W., Hussain S. P., Bowman E., Spillare E. A., Lipsky M. M., Meck J. M., Cavalli L. R., Haddad B. R. & Harris C. C.
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Cooperation of tumor-derived HBx mutants and p53-249ser mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line.
International Journal of Cancer.
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Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
Molecular Cell.
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Plant transformation by Agrobacterium tumefaciens: Modulation of single-stranded DNA-VirE2 complex assembly by VirE.
Journal of Biological Chemistry.
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Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions.
Molecular Systems Biology.
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Enzymes as viscoelastic catalytic machines.
Nature Physics.
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Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast.
Proceedings of the National Academy of Sciences of the United States of America.
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Highly active enzymes by automated combinatorial backbone assembly and sequence design.
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IceBear: An intuitive and versatile web application for research-data tracking from crystallization experiment to PDB deposition.
Acta Crystallographica Section D: Structural Biology.
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Biophysical characterization of the interaction of the β-lactamase TEM- 1 with its protein inhibitor BLIP.
Biochemistry.
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Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy.
Biochimica et Biophysica Acta - Molecular Basis of Disease.
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Sonawane P. D., Jozwiak A., Barbole R., Panda S., Abebie B., Kazachkova Y., Gharat S. A., Ramot O., Unger T., Wizler G., Meir S., Rogachev I., Doron-Faigenboim A., Petreikov M., Schaffer A., Giri A. P., Scherf T. & Aharoni A.
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New Phytologist.
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Pore-modulating toxins exploit inherent slow inactivation to block K+ channels.
Proceedings of the National Academy of Sciences of the United States of America.
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Tissue-specific (ts) CRISPR as an efficient strategy for in vivo screening in Drosophila.
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The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallographica Section D: Structural Biology.
79:(Pt 11)992-1009.
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The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function.
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Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. M., Burmeister W. P., Cambillau C., Canard B., Carrondo M. A., Coll M., Daenke S., Dym O., Egloff M. P., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q., Manicka S. N., Migliardi M., Nordlund P., Owens R. J., Peleg Y., Schneider G., Schnell R., Stuart D. I., Tarbouriech N., Unge T., Wilkinson A. J., Wilmanns M., Wilson K. S., Zimhony O. & Grimes J. M.
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Erratum: Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens (Acta Crystallographica Section D: Biological Crystallography (2006) D62 (1196-1207)).
Acta Crystallographica Section D: Biological Crystallography.
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Application of Restriction Free (RF) Cloning in Circular Permutation.
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Fine Tuning of Chlorophyll Spectra by Protein-Induced Ring Deformation.
Angewandte Chemie-International Edition.
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Implementation of semi-automated cloning and prokaryotic expression screening: The impact of SPINE.
Acta Crystallographica Section D: Biological Crystallography.
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High-Resolution Crystal Structure of Activated Cyt2Ba Monomer from Bacillus thuringiensis subsp. israelensis.
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Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression.
Molecular and Cellular Biology.
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SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution.
Nature Microbiology.
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Amalgam, an axon guidance Drosophila adhesion protein belonging to the immunoglobulin superfamily: Over-expression, purification and biophysical characterization.
Protein Expression and Purification.
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Stable Mammalian Serum Albumins Designed for Bacterial Expression.
Journal of Molecular Biology.
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Zeev-Ben-Mordehai T., Mylonas E., Paz A., Peleg Y., Toker L., Silman I., Svergun D. I. & Sussman J.
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Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimers disease phenotype in mice.
Journal of Clinical Investigation.
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Levin K. B., Dym O., Albeck S., Magdassi S., Keeble A. H., Kleanthous C. & Tawfik D. S.
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Following evolutionary paths to protein-protein interactions with high affinity and selectivity.
Nature Structural & Molecular Biology.
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Mapping of the bcl-2 oncogene on mouse chromosome 1.
Cytogenetics and Cell Genetics.
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Treating late-onset Tay Sachs disease: Brain delivery with a dual trojan horse protein.
Molecular Therapy Methods and Clinical Development.
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Mizrachi A., Sadeh M., Ben-Dor S., Dym O., Ku C., Feldmesser E., Zarfin A., Brunson J. K., Allen A. E., Jinkerson R. E., Schatz D. & Vardi A.
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Cathepsin X is a conserved cell death protein involved in algal response to environmental stress.
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Facilitating circular permutation using Restriction Free (RF) cloning.
Protein Engineering Design & Selection.
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Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration.
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Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli.
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Sensing Protein Surfaces with Targeted Fluorescent Receptors.
Chemistry - A European Journal.
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The biosynthetic pathway of the hallucinogen mescaline and its heterologous reconstruction.
Molecular Plant.
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CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens.
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A Single Gene Causes Thelytokous Parthenogenesis, the Defining Feature of the Cape Honeybee Apis mellifera capensis.
Current Biology.
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Protein production and purification.
Nature Methods.
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A concise guide to choosing suitable gene expression systems for recombinant protein production.
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Udi Y., Grossman M., Solomonov I., Dym O., Rozenberg H., Moreno V., Cuniasse P., Dive V., Arroyo A. G. & Sagi I.
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Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
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Increasing recombinant protein production in E. coli via FACS-based selection of N-terminal coding DNA libraries.
FEBS Journal.
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Origin of life: Protoribosome forms peptide bonds and links RNA and protein dominated worlds.
Nucleic Acids Research.
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Principles for computational design of binding antibodies.
Proceedings of the National Academy of Sciences of the United States of America.
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Biosynthesis of antinutritional alkaloids in solanaceous crops is mediated by clustered genes.
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Regulation of calcite crystal morphology by intracrystalline acidic proteins and glycoproteins.
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Protein Recognition by a Pattern-Generating Fluorescent Molecular Probe.
Nature Nanotechnology.
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Listov D., Vos E., Hoffka G., Hoch S. Y., Berg A., Hamer-Rogotner S., Dym O., Kamerlin S. C. L. & Fleishman S. J.
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Complete computational design of high-efficiency Kemp elimination enzymes.
Nature.
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Reichmann D., Rahat O., Albeck S., Meged R., Dym O. & Schreiber G.
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The modular architecture of protein-protein binding interfaces.
Proceedings of the National Academy of Sciences of the United States of America.
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Pokorna S., Khersonsky O., Lipsh-Sokolik R., Goldenzweig A., Nielsen R., Ashani Y., Peleg Y., Unger T., Albeck S., Dym O., Tirosh A., Tarayra R., Hocquemiller M., Laufer R., Ben-Dor S., Silman I., Sussman J. L., Fleishman S. J. & Futerman A. H.
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Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
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A single-tube assembly of DNA using the transfer-PCR (TPCR) platform.
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AcpM, the meromycolate extension Acyl carrier protein of mycobacterium tuberculosis, is activated by the 4-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.
Biochemistry.
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Cyt1Aa toxin: Crystal structure reveals implications for its membrane-perforating function.
Journal of Molecular Biology.
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Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N.
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Efficient targeted degradation via reversible and irreversible covalent PROTACs.
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Application of the Restriction-Free (RF) cloning for multicomponents assembly.
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Oxidative activity of yeast Ero1p on protein disulfide isomerase and related oxidoreductases of the endoplasmic reticulum.
Journal of Biological Chemistry.
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Prasad P. K., Toraskar S., Khan S., Granot T., Sirkis Y. F., Yardeni E. H., Albeck S., Unger T., Petrovich-Kopitman E., Addadi Y., Raigawali R., Anand S., Vishweshwara S. S., Shanthamurthy C. D., Oppenheimer-Low N., Kikkeri R., Avinoam O., Motiei L. & Margulies D.
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Low-Background His-Tag-Targeting Probes for Turn-On Fluorescence Detection of Cell Surface Proteins and Their Binding Interactions.
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Molecular Cell.
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Sonawane P. D., Heinig U., Panda S., Gilboa N. S., Yona M., Kumar S. P., Alkan N., Unger T., Bocobza S., Pliner M., Malitsky S., Tkachev M., Meir S., Rogachev I. & Aharoni A.
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Short-chain dehydrogenase/reductase governs steroidal specialized metabolites structural diversity and toxicity in the genus Solanum.
Proceedings of the National Academy of Sciences of the United States of America.
115:(23)E5419-E5428.
Saikia C., Altman-Gueta H., Dym O., Karbat I. & Reuveny E.
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Conkunitzin-C2 from Conus consors induces an incomplete block of the Shaker K+ channel using a unique mode of action.
Biophysical Journal.
121:(3(1))500a-500a.
Bab-Dinitz E., Albeck S., Peleg Y., Brumfeld V., Gottschalk K. E. & Karlish S. J.
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A C-terminal lobe of the β subunit of Na,K-ATPase and H,K-ATPase resembles cell adhesion molecules.
Biochemistry.
48:(36)8684-8691.
Ofir-Birin Y., Ben Ami Pilo H., Camacho A. C., Rudik A., Rivkin A., Revach O., Nir N., Tamin T. B., Karam P. A., Kiper E., Peleg Y., Nevo R., Solomon A., Havkin-Solomon T., Rojas A., Rotkopf R., Porat Z., Avni D., Schwartz E., Zillinger T., Hartmann G., Di Pizio A., Ben Quashie N., Dikstein R., Gerlic M., Torrecilhas A. C., Levy C., Hoen E. N. M. N., Bowie A. G. & Regev-Rudzki N.
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Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.
Nature Communications.
12:(1)
Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A.
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A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.
ChemBioChem.
16:(10)1415-1419.
Yadid I., Kirshenbaum N., Sharon M., Dym O. & Tawfik D.
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Metamorphic proteins mediate evolutionary transitions of structure.
Proceedings of the National Academy of Sciences of the United States of America.
107:(16)7287-7292.
Davidi D., Shamshoum M., Guo Z., Baron Y. M., Prywes N., Oz A., Jablonska J., Flamholz A., Wernick D. G., Antonovsky N., Pins B., Shachar L., Hochhauser D., Peleg Y., Albeck S., Sharon I., Muellercajar O. & Milo R.
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Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.
The EMBO Journal.
39:(18)
Oranges M., Giannoulis A., Vanyushkina A., Sirkis Y. F., Dalaloyan A., Unger T., Su X. C., Sharon M. & Goldfarb D.
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C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.
Biophysical Journal.
123:(2)172-183.
Reichmann D., Cohen M., Abramovich R., Dym O., Lim D., Strynadka N. C. J. & Schreiber G.
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Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
Journal of Molecular Biology.
365:(3)663-679.
Hatai J., Prasad P. K., Lahav-Mankovski N., Oppenheimer-Low N., Unger T., Sirkis Y. F., Dadosh T., Motiei L. & Margulies D.
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Assessing Changes in the Expression Levels of Cell Surface Proteins with a Turn-on Fluorescent Molecular Probe.
Chemical Communications.
57:(15)1875-1878.
Berrow N. S., Buessow K., Coutard B., Diprose J., Ekberg M., Folkers G. E., Levy N., Lieu V., Owens R. J., Peleg Y., Pinaglia C., Quevillon-Cheruel S., Salim L., Scheich C., Vincentelli R. & Busso D.
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Recombinant protein expression and solubility screening in Escherichia coli: A comparative study.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1218-1226.
Albeck S., Weiner S. & Addadi L.
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Polysaccharides of intracrystalline glycoproteins modulate calcite crystal growth in vitro.
Chemistry-A European Journal.
2:(3)278-284.
Katzir N., Rechavi G., Cohen J., Unger T., Simoni F., Segal S., Cohen D. & Givol D.
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'Retroposon' insertion into the cellular oncogene c-myc in canine transmissible venereal tumor.
Proceedings of the National Academy of Sciences of the United States of America.
82:(4)1054-1058.
Addadi L., Aizenberg J., Albeck S., Falini G. & Weiner S.
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Structural control over the formation of calcium carbonate mineral phases in biomineralization.
Supramolecular Stereochemistry.
473:127-139.
Juven-Gershon T., Shifman O., Unger T., Elkeles A., Haupt Y. & Oren M.
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The Mdm2 oncoprotein interacts with the cell fate regulator numb.
Molecular and Cellular Biology.
18:(7)3974-3982.
Shaaltiel Y., Bartfeld D., Hashmueli S., Baum G., Brill-Almon E., Galili G., Dym O., Boldin-Adamsky S. A., Silman I., Sussman J. L., Futerman A. H. & Aviezer D.
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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.
Plant Biotechnology Journal.
5:(5)579-590.
Selzer T., Albeck S. & Schreiber G.
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Rational design of faster associating and tighter binding protein complexes.
Nature Structural Biology.
7:(7)537-541.
Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z.
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Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.
Journal of Biological Chemistry.
298:(5)
Wong E., Maretzky T., Peleg Y., Blobel C. P. & Sagi I.
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The functional maturation of a disintegrin and metalloproteinase (ADAM) 9, 10, and 17 requires processing at a newly identified proprotein convertase (PC) cleavage site.
The journal of Biological chemistry.
290:(19)12135-12146.
Meged R., Dym O. & Sussman J. L.
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High throughput pH optimization of protein crystallization.
Methods in molecular biology (Clifton, N.J.).
426:411-418.
Dym O., Albeck S., Peleg Y., Schwarz A., Shakked Z., Burstein Y. & Zimhony O.
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Structure-Function Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis.
Journal of Molecular Biology.
393:(4)937-950.
Unger T., Jacobovitch Y., Dantes A., Bernheim R. & Peleg Y.
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Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression.
Journal of Structural Biology.
172:(1)34-44.
Peleg Y. & Unger T.
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Resolving bottlenecks for recombinant protein expression in E. coli.
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Community-Wide Experimental Evaluation of the PROSS Stability-Design Method.
Journal of Molecular Biology.
433:(13)
Peer L., Dym O., Elad N., Tirosh A., Jacobovitch J., Sivan E., Angel M., Albeck S., Schuldiner M., Peleg Y. & Zalckvar E.
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A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface.
Journal of Cell Science.
138:(12)
Busso D., Peleg Y., Heidebrecht T., Romier C., Jacobovitch Y., Dantes A., Salim L., Troesch E., Schuetz A., Heinemann U., Folkers G. E., Geerlof A., Wilmanns M., Polewacz A., Quedenau C., Buessow K., Adamson R., Blagova E., Walton J., Cartwright J. L., Bird L. E., Owens R. J., Berrow N. S., Wilson K. S., Sussman J., Perrakis A. & Celie P. H. N.
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Expression of protein complexes using multiple Escherichia coli protein co-expression systems: A benchmarking study.
Journal of Structural Biology.
175:(2)159-170.
Wong E., Cohen T., Romi E., Levin M., Peleg Y., Arad U., Yaron A., Milla M. E. & Sagi I.
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Harnessing the natural inhibitory domain to control TNF alpha Converting Enzyme (TACE) activity in vivo.
Scientific Reports.
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Yifrach E., Rudowitz M., Cruz-Zaragoza L. D., Tirosh A., Gazi Z., Peleg Y., Kunze M., Eisenstein M., Schliebs W., Schuldiner M., Erdmann R. & Zalckvar E.
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Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.
Biological Chemistry.
404:(2-3)121-133.
Khersonsky O., RöThlisberger D., Dym O., Albeck S., Jackson C. J., Baker D. & Tawfik D. S.
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Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the ke07 series.
Journal of Molecular Biology.
396:(4)1025-1042.
Goldsmith M., Avram L., Brandis A., Mehlman T., Ben-Dor S., Peleg Y., Ben-Zeev E., Barbole R. S. & Reich Z.
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LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.
Nature Communications.
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Sonawane P. D., Pollier J., Panda S., Szymanski J., Massalha H., Yona M., Unger T., Malitsky S., Arendt P., Pauwels L., Almekias-Siegl E., Rogachev I., Meir S., Cardenas P. D., Masri A., Petrikov M., Schaller H., Schaffer A. A., Kamble A., Giri A. P., Goossens A. & Aharoni A.
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Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.
Nature Plants.
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Yado S., Zoabi R., Brezinger-Dayan K., Albeck S., Unger T., Meiron M., Eisenberg G., Nahmad A. D., Gilat A. T., Besser M. J. & Geiger B.
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Differential effects of immobilized CCL21 and ICAM1 on TILs with distinct expansion properties.
Frontiers in Immunology.
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