Publications
Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D.
(2020).
Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.
Proceedings of the National Academy of Sciences of the United States of America.
117:(1)395-404.
Suzumoto Y., Dym O., Roviello G. N., Worek F., Sussman J. L. & Manco G.
(2020).
Structural and functional characterization of new ssopox variant points to the dimer interface as a driver for the increase in promiscuous paraoxonase activity.
International Journal of Molecular Sciences.
21:(5)
Prabahar V., Afriat-Jurnou L., Paluy I., Peleg Y. & Noy D.
(2020).
New homologues of Brassicaceae water-soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution.
FEBS Journal.
287:(5)991-1004.
Lahav-Mankovski N., Prasad P. K., Oppenheimer-Low N., Raviv G., Dadosh T., Unger T., Salame T. M., Motiei L. & Margulies D.
(2020).
Decorating bacteria with self-assembled synthetic receptors.
Nature Communications.
11:(1)
Rosenthal M., Metzl-Raz E., Buergi J., Yifrach E., Drwesh L., Fadel A., Peleg Y., Rapaport D., Wilmanns M., Barkai N., Schuldiner M. & Zalckvar E.
(2020).
Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.
Proceedings of the National Academy of Sciences of the United States of America.
117:(35)21432-21440.
Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J.
(2019).
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
PLoS Computational Biology.
15:(8)
Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D.
(2019).
Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.
ChemPhysChem.
20:(14)1860-1868.
Zahradnik J., Kolarova L., Peleg Y., Kolenko P., Svidenska S., Charnavets T., Unger T., Sussman J. L. & Schneider B.
(2019).
Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1.
FEBS Journal.
286:(19)3858-3873.
Novichkova D. A., Lushchekina S., Dym O., Masson P., Silman I. & Sussman J. L.
(2019).
The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability.
Chemico-Biological Interactions.
309.
Arafeh R., Di Pizio A., Elkahloun A. G., Dym O., Niv M. Y. & Samuels Y.
(2019).
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma.
Oncogene.
38:(13)2432-2434.
Karbat I., Altman-Gueta H., Fine S., Szanto T., Hamer-Rogotner S., Dym O., Frolow F., Gordon D., Panyi G., Gurevitz M. & Reuveny E.
(2019).
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels.
Proceedings of the National Academy of Sciences of the United States of America.
116:(37)18700-18709.
Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G.
(2018).
Manipulating the Folding Landscape of a Multi-Domain Protein.
Journal of Physical Chemistry B.
122:(49)11030-11038.
Netzer R., Listov D., Lipsh R., Dym O., Albeck S., Knop O., Kleanthous C. & Fleishman S. J.
(2018).
Ultrahigh specificity in a network of computationally designed protein-interaction pairs.
Nature Communications.
9:(1)
Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R.
(2018).
Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.
Nature Communications.
9:(1)
Karniel A., Mrusek D., Steinchen W., Dym O., Bange G. & Bibi E.
(2018).
Co-translational folding intermediate dictates membrane targeting of the signal recognition particle-receptor.
Journal of Molecular Biology.
430:(11)1607-1620.
Bandyopadhyay B. & Peleg Y.
(2018).
Facilitating circular permutation using Restriction Free (RF) cloning.
Protein Engineering Design & Selection.
31:(3)65-68.
Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M.
(2018).
Rapid characterization of secreted recombinant proteins by native mass spectrometry.
Communications Biology.
1:(1)
Sonawane P. D., Pollier J., Panda S., Szymanski J., Massalha H., Yona M., Unger T., Malitsky S., Arendt P., Pauwels L., Almekias-Siegl E., Rogachev I., Meir S., Cardenas P. D., Masri A., Petrikov M., Schaller H., Schaffer A. A., Kamble A., Giri A. P., Goossens A. & Aharoni A.
(2017).
Correction: Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism (vol 3, 16205, 2016).
Nature Plants.
3.
Bandyopadhyay B., Goldenzweig A., Unger T., Adato O., Fleishman S. J., Unger R. & Horovitz A.
(2017).
Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL.
Journal of Biological Chemistry.
292:(50)20583-20591.
Cohen-Khait R., Dym O., Hamer-Rogotner S. & Schreiber G.
(2017).
Promiscuous Protein Binding as a Function of Protein Stability.
Structure (London, England : 1993).
25:(12)1867-1874.e3.
Milrot E., Shimoni E., Dadosh T., Rechav K., Unger T., Van Etten E. J. L. & Minsky A.
(2017).
Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1.
PLoS Pathogens.
13:(8)
Dym O., Song W., Felder C., Roth E., Shnyrov V., Ashani Y., Xu Y., Joosten R. P., Weiner L., Sussman J. & Silman I.
(2016).
The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex.
Protein Science.
25:(6)1096-1114.
Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A.
(2015).
A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.
ChemBioChem.
16:(10)1415-1419.
Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D.
(2015).
[Cover Profile] Sensing Protein Surfaces with Targeted Fluorescent Receptors.
Chemistry (Weinheim an der Bergstrasse, Germany).
21:(45)15873-15873.
Sobolev V., Edelman M., Dym O., Unger T., Albeck S., Kirma M. & Galili G.
(2013).
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis.
Acta Crystallographica Section F-Structural Biology And Crystallization Communications.
69:(2)84-89.
Hama S., Soran H., Albeck S., Charlton-Menys V., Yadav R., Liu Y., France M., Tawfiq D. & Durrington P.
(2012).
High Paraoxonase-1 Hdl is More Effective Than Low Paraoxonase-1 Hdl in Impeding Ldl Oxidation in Vitro.
Atherosclerosis.
223:(2)529-529.
Carlessi R., Levin-Salomon V., Ciprut S., Bialik S., Berissi H., Albeck S., Peleg Y. & Kimchi A.
(2011).
GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.
EMBO Reports.
12:(9)917-923.
Karanicolas J., Com J. E., Chen I., Joachimiak L. A., Dym O., Peck S. H., Albeck S., Unger T., Hu W., Liu G., Delbecq S., Montelione G. T., Spiegel C. P., Liu D. R. & Baker D.
(2011).
A De Novo Protein Binding Pair By Computational Design and Directed Evolution.
Molecular Cell.
42:(2)250-260.
Unger T., Dym O., Albeck S., Jacobovitch Y., Bernehim R., Marom D., Pisanty O. & Breiman A.
(2010).
Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain.
Journal of Structural and Functional Genomics.
11:(2)113-23.
Dym O., Albeck S., Peleg Y., Schwarz A., Shakked Z., Burstein Y. & Zimhony O.
(2009).
Structure-Function Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis.
Journal of Molecular Biology.
393:(4)937-950.
Levin K. B., Dym O., Albeck S., Magdassi S., Keeble A. H., Kleanthous C. & Tawfik D.
(2009).
Following evolutionary paths to protein-protein interactions with high affinity and selectivity.
Nature Structural & Molecular Biology.
16:(10)1049-U67.
Sharabi O., Peleg Y., Mashiach E., Vardy E., Ashani Y., Simian I., Sussman J. L. & Shifman J. M.
(2009).
Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase.
Protein Engineering Design & Selection.
22:(10)641-648.
Liberman N., Dym O., Unger T., Albeck S., Peleg Y., Jacobovitch Y., Branzburg A., Eisenstein M., Marash L. & Kimchi A.
(2008).
The Crystal Structure of the C-Terminal DAP5/p97 Domain Sheds Light on the Molecular Basis for Its Processing by Caspase Cleavage.
Journal of Molecular Biology.
383:(3)539-548.
Dym O., Albeck S., Unger T., Jacobovitch J., Branzburg A., Michael Y., Frenkiel-Krispin D., Wolf S. G. & Elbaum M.
(2008).
Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.
Proceedings of the National Academy of Sciences of the United States of America.
105:(32)11170-11175.
Albeck S., Dym O., Unger T., Snapir Z., Bercovich Z. & Kahana C.
(2008).
Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function.
Protein Science.
17:(5)793-802.
Goihberg E., Dym O., Tel-Or S., Shimon L., Frolow F., Peretz M. & Burstein Y.
(2008).
Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.
Proteins-Structure Function And Bioinformatics.
72:(2)711-719.
Peleg Y. & Unger T.
(2008).
Application of High-Throughput Methodologies to the Expression of Recombinant Proteins in E. coli.
.
197-208.
Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. -., Burmeister W. P., Cambillau C., Canard B., Carrondo M., Coll M., Daenke S., Dym O., Egloff M. -., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q. & Manicka S. N.
(2006).
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1196-1207.
Shao H., Revach M., Moshonov S., Tzuman Y., Gazit K., Albeck S., Unger T. & Dikstein R.
(2005).
Core promoter binding by histone-like TAF complexes.
Molecular and Cellular Biology.
25:(1)206-219.
Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A.
(2002).
Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.
Journal of Biological Chemistry.
277:(48)46304-46309.
Unger T., Oren Z. & Shai Y.
(2001).
The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: Implication to their mode of action.
Biochemistry.
40:(21)6388-6397.
Unger T., Sionov R., Moallem E., Yee C., Howley P., Oren M. & Haupt Y.
(1999).
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
Oncogene.
18:(21)3205-3212.
Unger T., Juven-Gershon T., Moallem E., Berger M., Sionov R., Lozano G., Oren M. & Haupt Y.
(1999).
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
EMBO Journal.
18:(7)1805-1814.
Mor F., Boccaccio G. & Unger T.
(1998).
Expression of autoimmune disease-related antigens by cells of the immune system.
Journal of Neuroscience Research.
54:(2)254-262.
Tamary H., Fromovich Y., Shalmon L., Reich Z., Dym O., Lanir N., Brenner B., Paz M., Luder A., Blau O., Korostishevsky M., Zaizov R. & Seligsohn U.
(1996).
Ala244Val is a common, probably ancient mutation causing factor VII deficiency in Moroccan and Iranian Jews.
Thrombosis and Haemostasis.
76:(3)283-291.
Fiscella M., Zambrano N., Ullrich S. J., Unger T., Lin D., Cho B., Mercer W. E., Anderson C. W. & Appella E.
(1994).
The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.
Oncogene.
9:(11)3249-57.
Unger T., Nau M. M., Segal S. & Minna J. D.
(1992).
p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer.
EMBO Journal.
11:(4)1383-90.
Mietz J. A., Unger T., Huibregtse J. M. & Howley P. M.
(1992).
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.
EMBO Journal.
11:(13)5013-20.
Unger T. & Shaul Y.
(1990).
The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element.
EMBO Journal.
9:(6)1889-1895.
Meltzer H., Marom E., Alyagor I., Mayseless O., Berkun V., Segal-Gilboa N., Unger T., Luginbuhl D. & Schuldiner O.
().
Tissue-specific (ts) CRISPR as an efficient strategy for in vivo screening in Drosophila.
Nature Communications.
10:(1)
Yifrach E., Rudowitz M., Cruz-Zaragoza L. D., Tirosh A., Gazi Z., Peleg Y., Kunze M., Eisenstein M., Schliebs W., Schuldiner M., Erdmann R. & Zalckvar E.
().
Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.
Biological Chemistry.
404:(2-3)121-133.
Albeck S., Aizenberg J., Addadi L. & Weiner S.
().
Interactions of Various Skeletal Intracrystalline Components with Calcite Crystals.
Journal of the American Chemical Society.
115:(25)11691-11697.
Cohen S., Albeck S., Ben-Dov E., Cahan R., Firer M., Zaritsky A. & Dym O.
().
Cyt1Aa toxin: Crystal structure reveals implications for its membrane-perforating function.
Journal of Molecular Biology.
413:(4)804-814.
Tal L., Friedlander G., Gilboa N. S., Unger T., Gilad S. & Eshed Y.
().
Coordination of Meristem Doming and the Floral Transition by Late Termination, a Kelch Repeat Protein.
Plant Cell.
29:(4)681-696.
Sela-Passwell N. A., Kikkeri R., Dym O., Rozenberg H., Margalit R., Arad-Yellin R., Eisenstein M., Brenner O., Shoham T., Danon T., Shanzer A. & Sagi I.
().
Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential.
Nature Medicine.
18:(1)143-147.
Oranges M., Giannoulis A., Vanyushkina A., Sirkis Y. F., Dalaloyan A., Unger T., Su X. C., Sharon M. & Goldfarb D.
().
C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.
Biophysical Journal.
Berrow N. S., Buessow K., Coutard B., Diprose J., Ekberg M., Folkers G. E., Levy N., Lieu V., Owens R. J., Peleg Y., Pinaglia C., Quevillon-Cheruel S., Salim L., Scheich C., Vincentelli R. & Busso D.
().
Recombinant protein expression and solubility screening in Escherichia coli: A comparative study.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1218-1226.
Heyne M., Shirian J., Cohen I., Peleg Y., Radisky E. S., Papo N. & Shifman J. M.
().
Climbing up and down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes.
Journal of the American Chemical Society.
143:(41)17261-17275.
Shpilka T., Welter E., Borovsky N., Amar N., Shimron F., Peleg Y. & Elazar Z.
().
Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast.
Proceedings of the National Academy of Sciences of the United States of America.
112:(5)1434-1439.
Baron S., Peleg Y., Grunwald J., Morgenstern D., Elad N., Peretz M., Albeck S., Levin Y., Welch J. T., Deweerd K. A., Schwarz A., Burstein Y., Diskin R., Shakked Z. & Zimhony O.
().
Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli.
PLoS ONE.
(9)
Romier C., Ben Jelloul M., Albeck S., Buchwald G., Busso D., Celie P. H., Christodoulou E., De Marco V., Van Gerwen S., Knipscheer P., Lebbink J. H., Notenboom V., Poterszman A., Rochel N., Cohen S. X., Unger T., Sussman J. L., Moras D., Sixma T. K. & Perrakis A.
().
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: Experimental procedures, database tracking and case studies.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1232-1242.
Vitu E., Kim S., Sevier C. S., Lutzky O., Heldman N., Bentzur M., Unger T., Yona M., Kaiser C. A. & Fass D.
().
Oxidative activity of yeast Ero1p on protein disulfide isomerase and related oxidoreductases of the endoplasmic reticulum.
Journal of Biological Chemistry.
285:(24)18155-18165.
Cardenas P. D., Sonawane P. D., Heinig U., Jozwiak A., Panda S., Abebie B., Kazachkova Y., Pliner M., Unger T., Wolf D., Ofner I., Vilaprinyo E., Meir S., Davydov O., Gal-On A., Burdman S., Giri A., Zamir D., Scherf T., Szymanski J., Rogachev I. & Aharoni A.
().
Pathways to defense metabolites and evading fruit bitterness in genus Solanum evolved through 2-oxoglutarate-dependent dioxygenases.
Nature Communications.
10.
Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z.
().
Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.
The journal of Biological chemistry.
298:(5)
Mishra N. K., Peleg Y., Cirri E., Belogus T., Lifshitz Y., Voelker D. R., Apell H., Garty H. & Karlish S. J.
().
FXYD proteins stabilize Na,K-ATpase: Amplification of specific phosphatidylserine-protein interactions.
Journal of Biological Chemistry.
286:(11)9699-9712.
Tarayrah-Ibraheim L., Maurice E. C., Hadary G., Ben-Hur S., Kolpakova A., Braun T., Peleg Y., Yacobi-Sharon K. & Arama E.
().
DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.
Nature Communications.
12:(1)
Zeev-Ben-Mordehai T., Paz A., Peleg Y., Toker L., Wolf S. G., Rydberg E. H., Sussman J. & Silman I.
().
Amalgam, an axon guidance Drosophila adhesion protein belonging to the immunoglobulin superfamily: Over-expression, purification and biophysical characterization.
Protein Expression and Purification.
63:(2)147-157.
Goldenzweig A., Goldsmith M., Hill S. E., Gertman O., Laurino P., Ashani Y., Dym O., Unger T., Albeck S., Prilusky J., Lieberman R. L., Aharoni A., Silman I., Sussman J., Tawfik D. & Fleishman S. J.
().
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Molecular Cell.
63:(2)337-346.
Peleg Y. & Unger T.
().
Application of the Restriction-Free (RF) cloning for multicomponents assembly.
.
73-87.
Berry I. M., Dym O., Esnouf R. M., Harlos K., Meged R., Perrakis A., Sussman J., Walter T. S., Wilson J. & Messerschmidt A.
().
SPINE high-throughput crystallization, crystal imaging and recognition techniques: Current state, performance analysis, new technologies and future aspects.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1137-1149.
Gould N. L., Scherer G. R., Carvalho S., Shurrush K., Kayyal H., Edry E., Elkobi A., David O., Foqara M., Thakar D., Pavesi T., Sharma V., Walker M., Maitland M., Dym O., Albeck S., Peleg Y., Germain N., Babaev I., Sharir H., Lalzar M., Shklyar B., Hazut N., Khamaisy M., LéVesque M., Lajoie G., Avoli M., Amitai G., Lefker B., Subramanyam C., Shilton B., Barr H. & Rosenblum K.
().
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimers disease phenotype in mice.
Journal of Clinical Investigation.
133:(19)
Graslund S., Peleg Y., Albeck S., Unger T., Dym O., Prilusky J. & Sussman J. L.
().
Protein production and purification.
Nature Methods.
5:(2)135-146.
Rozenberg A., Kaczmarczyk I., Matzov D., Vierock J., Nagata T., Sugiura M., Katayama K., Kawasaki Y., Konno M., Nagasaka Y., Aoyama M., Das I., Pahima E., Church J., Adam S., Borin V. A., Chazan A., Augustin S., Wietek J., Dine J., Peleg Y., Kawanabe A., Fujiwara Y., Yizhar O., Sheves M., Schapiro I., Furutani Y., Kandori H., Inoue K., Hegemann P., Beja O. & Shalev-Benami M.
().
Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels.
Nature Structural and Molecular Biology.
29:(6)592-603.
Albeck S. & Schreiber G.
().
Biophysical characterization of the interaction of the β-lactamase TEM- 1 with its protein inhibitor BLIP.
Biochemistry.
38:(1)11-21.
Cohen S., Dym O., Albeck S., Ben-Dov E., Cahan R., Firer M. & Zaritsky A.
().
High-Resolution Crystal Structure of Activated Cyt2Ba Monomer from Bacillus thuringiensis subsp. israelensis.
Journal of Molecular Biology.
380:(5)820-827.
Sonawane P. D., Pollier J., Panda S., Szymanski J., Massalha H., Yona M., Unger T., Malitsky S., Arendt P., Pauwels L., Almekias-Siegl E., Rogachev I., Meir S., Cardenas P. D., Masri A., Petrikov M., Schaller H., Schaffer A. A., Kamble A., Giri A. P., Goossens A. & Aharoni A.
().
Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.
Nature Plants.
3.
RöThlisberger D., Khersonsky O., Wollacott A. M., Jiang L., Dechancie J., Betker J., Gallaher J. L., Althoff E. A., Zanghellini A., Dym O., Albeck S., Houk K. N., Tawfik D. S. & Baker D.
().
Kemp elimination catalysts by computational enzyme design.
Nature.
453:(7192)190-195.
Aizenberg J., Albeck S., Weiner S. & Addadi L.
().
Crystal-protein interactions studied by overgrowth of calcite on biogenic skeletal elements.
Journal of Crystal Growth.
142:(1-2)156-164.
Busso D., Peleg Y., Heidebrecht T., Romier C., Jacobovitch Y., Dantes A., Salim L., Troesch E., Schuetz A., Heinemann U., Folkers G. E., Geerlof A., Wilmanns M., Polewacz A., Quedenau C., Buessow K., Adamson R., Blagova E., Walton J., Cartwright J. L., Bird L. E., Owens R. J., Berrow N. S., Wilson K. S., Sussman J., Perrakis A. & Celie P. H. N.
().
Expression of protein complexes using multiple Escherichia coli protein co-expression systems: A benchmarking study.
Journal of Structural Biology.
175:(2)159-170.
Adams E. M., Pezzotti S., Ahlers J., RüTtermann M., Levin M., Goldenzweig A., Peleg Y., Fleishman S. J., Sagi I. & Havenith M.
().
Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction.
JACS Au.
1:(7)1076-1085.
Xu Y., Li M., Greenblatt H., Chen W., Paz A., Dym O., Peleg Y., Chen T., Shen X., He J., Jiang H., Silman I. & Sussman J.
().
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations.
Acta Crystallographica Section D: Biological Crystallography.
68:(1)13-25.
Bose T., Fridkin G., Davidovich C., Krupkin M., Dinger N., Falkovich A. H., Peleg Y., Agmon I., Bashan A. & Yonath A.
().
Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds.
Nucleic Acids Research.
50:(4)1815-1828.
Itkin M., Heinig U., Tzfadia O., Bhide A. J., Shinde B. A., Cardenas P. D., Bocobza S. E., Unger T., Malitsky S., Finkers R., Tikunov Y., Bovy A., Chikate Y. R., Singh P., Rogachev I., Beekwilder J., Giri A. P. & Aharoni A.
().
Biosynthesis of antinutritional alkaloids in solanaceous crops is mediated by clustered genes.
Science.
341:(6142)175-179.
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Conformation-specific inhibitory anti-mmp-7 monoclonal antibody sensitizes pancreatic ductal adenocarcinoma cells to chemotherapeutic cell kill.
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A Molecular Lid Mechanism of K+ Channel Blocker Action Revealed by a Cone Peptide.
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Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration.
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The functional maturation of a disintegrin and metalloproteinase (ADAM) 9, 10, and 17 requires processing at a newly identified proprotein convertase (PC) cleavage site.
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Stable Mammalian Serum Albumins Designed for Bacterial Expression.
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Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12.
Proteins-Structure Function And Bioinformatics.
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The human interferon receptor: NMR-based modeling, mapping of the IFN-α2 binding site, and observed ligand-induced tightening.
Biochemistry.
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Ben-Nissan G., Belov M. E., Morgenstern D., Levin Y., Dym O., Arkind G., Lipson G., Makarov A. A. & Sharon M.
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Triple-Stage Mass Spectrometry Unravels the Heterogeneity of an Endogenous Protein Complex.
Analytical Chemistry.
89:(8)4708-4715.
Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar Avihail A. A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., Amitai G. & Sorek R.
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Communication between viruses guides lysis-lysogeny decisions.
Nature.
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A concise guide to choosing suitable gene expression systems for recombinant protein production.
STAR Protocols.
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Yosef E., Katz A., Peleg Y., Mehlman T. & Karlish S. J.
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Do Src kinase and caveolin interact directly with Na,K-ATPase?.
Journal of Biological Chemistry.
291:(22)11736-11750.
Goldsmith M., Avram L., Brandis A., Mehlman T., Ben-Dor S., Peleg Y., Ben-Zeev E., Barbole R. S. & Reich Z.
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LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.
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The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.
Biochemistry.
45:(20)6372-6378.
Hatai J., Prasad P. K., Lahav-Mankovski N., Oppenheimer-Low N., Unger T., Sirkis Y. F., Dadosh T., Motiei L. & Margulies D.
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Assessing changes in the expression levels of cell surface proteins with a turn-on fluorescent molecular probe.
Chemical Communications.
57:(15)1875-1878.
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Implementation of semi-automated cloning and prokaryotic expression screening: The impact of SPINE.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1103-1113.
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Treating late-onset Tay Sachs disease: Brain delivery with a dual trojan horse protein.
Molecular Therapy Methods and Clinical Development.
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Khersonsky O., Lipsh R., Avizemer Z., Ashani Y., Goldsmith M., Leader H., Dym O., Rogotner S., Trudeau D. L., Prilusky J., Amengual-Rigo P., Guallar V., Tawfik D. S. & Fleishman S. J.
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Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
Molecular Cell.
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Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
FEBS Journal.
290:(13)3383-3399.
Li M., Greenblatt H. M., Dym O., Albeck S., Pais A., Gunanathan C., Milstein D., Degani H. & Sussman J.
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Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators.
Journal of Medicinal Chemistry.
54:(10)3575-3580.
Israeli H., Degtjarik O., Fierro F., Chunilal V., Gill A. K., Roth N. J., Botta J., Prabahar V., Peleg Y., Chan L. F., Ben-Zvi D., Mccormick P. J., Niv M. Y. & Shalev-Benami M.
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Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.
Science (American Association for the Advancement of Science).
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Ben-David M., Soskine M., Dubovetskyi A., Cherukuri K., Dym O., Sussman J. L., Liao Q., Szeler K., Kamerlin S. C. L. & Tawfik D. S.
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Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition.
Molecular Biology and Evolution.
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Albeck S., Weiner S. & Addadi L.
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Polysaccharides of intracrystalline glycoproteins modulate calcite crystal growth in vitro.
Chemistry-A European Journal.
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Mock B., Givol D., Dhoostelaere L., Huppi K., Seldin M., Gurfinkel N., Unger T., Potter M. & Mushinski J.
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Mapping of the bcl-2 oncogene on mouse chromosome 1.
Cytogenetics and Cell Genetics.
47:(1-2)11-15.
Reichmann D., Cohen M., Abramovich R., Dym O., Lim D., Strynadka N. C. J. & Schreiber G.
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Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
Journal of Molecular Biology.
365:(3)663-679.
Giannoulis A., Feintuch A., Unger T., Amir S. & Goldfarb D.
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Monitoring the Conformation of the Sba1/Hsp90 Complex in the Presence of Nucleotides with Mn(II)-Based Double ElectronElectron Resonance.
Journal of Physical Chemistry Letters.
12:(51)12235-12241.