MR microscopy: pushing resolution in space and time

We develop MR microscopy methodologies that push the limits of spatial resolution, temporal resolution, and quantitative inference. On the temporal side, we develop ultrafast fMRI acquisitions with advanced computational analyses and multimodal readouts to link understand information flow and oscillatory signals and their underlying neuronal drivers. On the spatial side, we develop ultrahigh-resolution in vivo MRI and analysis pipelines, aiming to resolve small cell clusters with multiple contrasts, and applying them to rodent models of plasticity and disease to track how evolves over time and how it relates to function. We further validate our work with advanced microscopy and histological approaches.