Research

Active Control of Liquid-Liquid phase separation

We study how cytoskeletal forces and flows reshape biomolecular condensates, focusing on tau-rich droplets and their mechanical regulation in vitro. In parallel, we utilize DNA nanotechnology to construct multi-arm DNA molecules that undergo liquid-liquid phase separation, enabling precise control over droplet formation and properties across a wide parameter space.

Feedback In Active Systems

To address the challenge of designing autonomous responsive materials, we aim to implement self-regulation mechanisms in reconstituted systems.