An integrative approach for the exploration of melanoma genetic and immunological interactions

Why do some people succumb to infection - while others don't?

We study the functional roles of epigenetics during cell-fate decisions

We study interactions between peripheral circadian clocks and exercise physiology, hypoxia signaling and metabolic pathways

We are interested to learn basic principles dictating specificity of proteinprotein interactions and how this relates to cell signaling

We identify systemic metabolic changes within the host that accompany or cause cancer

We seek a molecular understanding of membrane remodeling and its contribution to health and disease

The synaptic basis for sexual dimorphism in the nervous system

We develop algorithms and utilize single cell genomics for studying the organization and function of immune cells in a tissue

Drug resistance in cancer, effects that intra-tumor bacteria on cancer biology and drug resistance, ex vivo organ culture for the prediction of drug response

We study how osteoclasts, the only cells in our body that can degrade bone, are formed and how they function, both in health and in disease