Prof. Michal Neeman
The vascular bed is essential for survival of all multicellular organisms larger than a millimeter. Accordingly, structural and functional changes of tissues, in health and disease, during development or degeneration, are accompanied and often induced by vascular changes. This is particularly true for mammalian reproduction, embryo implantation and placenta function.
The aim of our work is to map the regulatory network controlling the growth and function of blood and lymphatic vessels. Novel MRI tools, accompanied by advanced optical modalities, allow us to non-invasively obtain dynamic information on activity of multiple steps in the angiogenic process during reproduction and pregnancy, and thereby improves our understanding of the key regulatory elements and critical checkpoints of vascular remodeling.