Research

Development and cell biology of crystal-forming cells

We study how crystal-forming cells create and control bio-organic crystals to produce a range of optical effects. Using zebrafish, we combine advanced physical and biological techniques, such as CRISPR, cryoEM, super-resolution imaging, and mass spectrometry imaging,  to explore the synthesis, trafficking, and assembly of these crystals at the cellular level.

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New bio-crystals, architectures and functions

We investigate novel bio-organic crystals in diverse species using spectroscopy and microscopy to discover new crystalline materials and understand their architecture and biological functions.

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Pathological crystallization

We study the mechanisms underlying kidney stone formation in both physiological and pathological contexts, aiming to identify key molecular regulators and develop new therapeutic strategies for conditions like kidney stones and gout.

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