Fleishman, Sarel-Jacob
Dr. Sarel Fleishman started his academic career in the Adi Lautman Interdisciplinary
Program for Outstanding Students in Tel Aviv University where he studied molecular
biology, chemistry, physics, history, and philosophy. He conducted his Ph.D. research
as a Clore Doctoral Fellow with Prof. Nir Ben-Tal in Tel-Aviv University where he
developed novel tools for predicting structure and dynamics in membrane proteins.
Several of his predictions on membrane transporters, channels, and receptors, were
subsequently proved experimentally, and Sarel earned the prestigious Science
Magazine and GE Healthcare Award for Young Life Scientists for these studies.
Following completion of his Ph.D., Sarel conducted his postdoctoral training as
a Human Frontier Fellow with Prof. David Baker at the University of Washington
(Seattle), where he developed the first general methodology for de novo design of
protein interactions. He applied this approach to generate novel protein inhibitors of
influenza hemagglutinin, which neutralize pathogenic influenza strains. Such methods
could unlock the vast potential of controlling molecular interaction networks, producing
novel diagnostics and therapeutics. Sarel joined the Weizmann Institute's Department
of Biological Chemistry in the summer of 2011.
Dr. Fleishman lives in Rehovot with his wife Dana, their three children, Ariel,
Aviv, and Myron, and their dog Tuka. In his spare time he enjoys jogging, hiking,
reading, classical music, and the never-changing blue sky of Israel.