Publications
Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D.
(2020).
Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.
Proceedings of the National Academy of Sciences of the United States of America.
117:(1)395-404.
Suzumoto Y., Dym O., Roviello G. N., Worek F., Sussman J. L. & Manco G.
(2020).
Structural and functional characterization of new ssopox variant points to the dimer interface as a driver for the increase in promiscuous paraoxonase activity.
International Journal of Molecular Sciences.
21:(5)
Prabahar V., Afriat-Jurnou L., Paluy I., Peleg Y. & Noy D.
(2020).
New homologues of Brassicaceae water-soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution.
FEBS Journal.
287:(5)991-1004.
Lahav-Mankovski N., Prasad P. K., Oppenheimer-Low N., Raviv G., Dadosh T., Unger T., Salame T. M., Motiei L. & Margulies D.
(2020).
Decorating bacteria with self-assembled synthetic receptors.
Nature Communications.
11:(1)
Rosenthal M., Metzl-Raz E., Buergi J., Yifrach E., Drwesh L., Fadel A., Peleg Y., Rapaport D., Wilmanns M., Barkai N., Schuldiner M. & Zalckvar E.
(2020).
Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.
Proceedings of the National Academy of Sciences of the United States of America.
117:(35)21432-21440.
Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J.
(2019).
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
PLoS Computational Biology.
15:(8)
Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D.
(2019).
Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.
ChemPhysChem.
20:(14)1860-1868.
Novichkova D. A., Lushchekina S., Dym O., Masson P., Silman I. & Sussman J. L.
(2019).
The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability.
Chemico-Biological Interactions.
309.
Arafeh R., Di Pizio A., Elkahloun A. G., Dym O., Niv M. Y. & Samuels Y.
(2019).
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma.
Oncogene.
38:(13)2432-2434.
Karbat I., Altman-Gueta H., Fine S., Szanto T., Hamer-Rogotner S., Dym O., Frolow F., Gordon D., Panyi G., Gurevitz M. & Reuveny E.
(2019).
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels.
Proceedings of the National Academy of Sciences of the United States of America.
116:(37)18700-18709.
Zahradnik J., Kolarova L., Peleg Y., Kolenko P., Svidenska S., Charnavets T., Unger T., Sussman J. L. & Schneider B.
(2019).
Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1.
FEBS Journal.
286:(19)3858-3873.
Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G.
(2018).
Manipulating the Folding Landscape of a Multi-Domain Protein.
Journal of Physical Chemistry B.
122:(49)11030-11038.
Netzer R., Listov D., Lipsh R., Dym O., Albeck S., Knop O., Kleanthous C. & Fleishman S. J.
(2018).
Ultrahigh specificity in a network of computationally designed protein-interaction pairs.
Nature Communications.
9:(1)
Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R.
(2018).
Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.
Nature Communications.
9.
Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M.
(2018).
Rapid characterization of secreted recombinant proteins by native mass spectrometry.
Communications Biology.
1.
Karniel A., Mrusek D., Steinchen W., Dym O., Bange G. & Bibi E.
(2018).
Co-translational folding intermediate dictates membrane targeting of the signal recognition particle-receptor.
Journal of Molecular Biology.
430:(11)1607-1620.
Bandyopadhyay B. & Peleg Y.
(2018).
Facilitating circular permutation using Restriction Free (RF) cloning.
Protein Engineering Design & Selection.
31:(3)65-68.
Bandyopadhyay B., Goldenzweig A., Unger T., Adato O., Fleishman S. J., Unger R. & Horovitz A.
(2017).
Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL.
Journal of Biological Chemistry.
292:(50)20583-20591.
Cohen-Khait R., Dym O., Hamer-Rogotner S. & Schreiber G.
(2017).
Promiscuous Protein Binding as a Function of Protein Stability.
Structure (London, England : 1993).
25:(12)1867-1874.e3.
Milrot E., Shimoni E., Dadosh T., Rechav K., Unger T., Van Etten E. J. L. & Minsky A.
(2017).
Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1.
PLoS Pathogens.
13:(8)
Sonawane P. D., Pollier J., Panda S., Szymanski J., Massalha H., Yona M., Unger T., Malitsky S., Arendt P., Pauwels L., Almekias-Siegl E., Rogachev I., Meir S., Cardenas P. D., Masri A., Petrikov M., Schaller H., Schaffer A. A., Kamble A., Giri A. P., Goossens A. & Aharoni A.
(2017).
Correction: Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism (vol 3, 16205, 2016).
Nature Plants.
3.
Dym O., Song W., Felder C., Roth E., Shnyrov V., Ashani Y., Xu Y., Joosten R. P., Weiner L., Sussman J. & Silman I.
(2016).
The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex.
Protein Science.
25:(6)1096-1114.
Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A.
(2015).
A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.
ChemBioChem.
16:(10)1415-1419.
Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D.
(2015).
[Cover Profile] Sensing Protein Surfaces with Targeted Fluorescent Receptors.
Chemistry (Weinheim an der Bergstrasse, Germany).
21:(45)15873-15873.
Sobolev V., Edelman M., Dym O., Unger T., Albeck S., Kirma M. & Galili G.
(2013).
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis.
Acta Crystallographica Section F-Structural Biology And Crystallization Communications.
69:(2)84-89.
Hama S., Soran H., Albeck S., Charlton-Menys V., Yadav R., Liu Y., France M., Tawfiq D. & Durrington P.
(2012).
High Paraoxonase-1 Hdl is More Effective Than Low Paraoxonase-1 Hdl in Impeding Ldl Oxidation in Vitro.
Atherosclerosis.
223:(2)529-529.
Carlessi R., Levin-Salomon V., Ciprut S., Bialik S., Berissi H., Albeck S., Peleg Y. & Kimchi A.
(2011).
GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.
EMBO Reports.
12:(9)917-923.
Karanicolas J., Com J. E., Chen I., Joachimiak L. A., Dym O., Peck S. H., Albeck S., Unger T., Hu W., Liu G., Delbecq S., Montelione G. T., Spiegel C. P., Liu D. R. & Baker D.
(2011).
A De Novo Protein Binding Pair By Computational Design and Directed Evolution.
Molecular Cell.
42:(2)250-260.
Unger T., Dym O., Albeck S., Jacobovitch Y., Bernehim R., Marom D., Pisanty O. & Breiman A.
(2010).
Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain.
Journal of Structural and Functional Genomics.
11:(2)113-23.
Dym O., Albeck S., Peleg Y., Schwarz A., Shakked Z., Burstein Y. & Zimhony O.
(2009).
Structure-Function Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis.
Journal of Molecular Biology.
393:(4)937-950.
Levin K. B., Dym O., Albeck S., Magdassi S., Keeble A. H., Kleanthous C. & Tawfik D.
(2009).
Following evolutionary paths to protein-protein interactions with high affinity and selectivity.
Nature Structural & Molecular Biology.
16:(10)1049-U67.
Sharabi O., Peleg Y., Mashiach E., Vardy E., Ashani Y., Simian I., Sussman J. L. & Shifman J. M.
(2009).
Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase.
Protein Engineering Design & Selection.
22:(10)641-648.
Liberman N., Dym O., Unger T., Albeck S., Peleg Y., Jacobovitch Y., Branzburg A., Eisenstein M., Marash L. & Kimchi A.
(2008).
The Crystal Structure of the C-Terminal DAP5/p97 Domain Sheds Light on the Molecular Basis for Its Processing by Caspase Cleavage.
Journal of Molecular Biology.
383:(3)539-548.
Dym O., Albeck S., Unger T., Jacobovitch J., Branzburg A., Michael Y., Frenkiel-Krispin D., Wolf S. G. & Elbaum M.
(2008).
Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.
Proceedings of the National Academy of Sciences of the United States of America.
105:(32)11170-11175.
Albeck S., Dym O., Unger T., Snapir Z., Bercovich Z. & Kahana C.
(2008).
Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function.
Protein Science.
17:(5)793-802.
Goihberg E., Dym O., Tel-Or S., Shimon L., Frolow F., Peretz M. & Burstein Y.
(2008).
Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.
Proteins-Structure Function And Bioinformatics.
72:(2)711-719.
Peleg Y. & Unger T.
(2008).
Application of High-Throughput Methodologies to the Expression of Recombinant Proteins in E. coli.
.
197-208.
Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. -., Burmeister W. P., Cambillau C., Canard B., Carrondo M., Coll M., Daenke S., Dym O., Egloff M. -., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q. & Manicka S. N.
(2006).
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1196-1207.
Shao H., Revach M., Moshonov S., Tzuman Y., Gazit K., Albeck S., Unger T. & Dikstein R.
(2005).
Core promoter binding by histone-like TAF complexes.
Molecular and Cellular Biology.
25:(1)206-219.
Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A.
(2002).
Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.
Journal of Biological Chemistry.
277:(48)46304-46309.
Unger T., Oren Z. & Shai Y.
(2001).
The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: Implication to their mode of action.
Biochemistry.
40:(21)6388-6397.
Unger T., Juven-Gershon T., Moallem E., Berger M., Sionov R., Lozano G., Oren M. & Haupt Y.
(1999).
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
EMBO Journal.
18:(7)1805-1814.
Unger T., Sionov R., Moallem E., Yee C., Howley P., Oren M. & Haupt Y.
(1999).
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
Oncogene.
18:(21)3205-3212.
Mor F., Boccaccio G. & Unger T.
(1998).
Expression of autoimmune disease-related antigens by cells of the immune system.
Journal of Neuroscience Research.
54:(2)254-262.
Albeck S., Addadi L. & Weiner S.
(1996).
Regulation of calcite crystal morphology by intracrystalline acidic proteins and glycoproteins.
Connective Tissue Research.
35:(1-4)365-370.
Tamary H., Fromovich Y., Shalmon L., Reich Z., Dym O., Lanir N., Brenner B., Paz M., Luder A., Blau O., Korostishevsky M., Zaizov R. & Seligsohn U.
(1996).
Ala244Val is a common, probably ancient mutation causing factor VII deficiency in Moroccan and Iranian Jews.
Thrombosis and Haemostasis.
76:(3)283-291.
Addadi L., Aizenberg J., Albeck S., Falini G. & Weiner S.
(1995).
Structural control over the formation of calcium carbonate mineral phases in biomineralization.
Supramolecular Stereochemistry.
473:127-139.
Fiscella M., Zambrano N., Ullrich S. J., Unger T., Lin D., Cho B., Mercer W. E., Anderson C. W. & Appella E.
(1994).
The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.
Oncogene.
9:(11)3249-57.
Mietz J. A., Unger T., Huibregtse J. M. & Howley P. M.
(1992).
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.
EMBO Journal.
11:(13)5013-20.
Unger T., Nau M. M., Segal S. & Minna J. D.
(1992).
p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer.
EMBO Journal.
11:(4)1383-90.
Unger T. & Shaul Y.
(1990).
The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element.
EMBO Journal.
9:(6)1889-1895.
Heyne M., Shirian J., Cohen I., Peleg Y., Radisky E. S., Papo N. & Shifman J. M.
().
Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein–Protein Complexes.
Journal of the American Chemical Society.
143:(41)17261-17275.
Albeck S. & Schreiber G.
().
Biophysical characterization of the interaction of the β-lactamase TEM- 1 with its protein inhibitor BLIP.
Biochemistry.
38:(1)11-21.
Sberro H., Leavitt A., Kiro R., Koh E., Peleg Y., Qimron U. & Sorek R.
().
Discovery of Functional Toxin/Antitoxin Systems in Bacteria by Shotgun Cloning.
Molecular Cell.
50:(1)136-148.
Khersonsky O., Kiss G., RöThlisberger D., Dym O., Albeck S., Houk K. N., Baker D. & Tawfik D. S.
().
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.
Proceedings of the National Academy of Sciences of the United States of America.
109:(26)10358-10363.
Vitu E., Kim S., Sevier C. S., Lutzky O., Heldman N., Bentzur M., Unger T., Yona M., Kaiser C. A. & Fass D.
().
Oxidative activity of yeast Ero1p on protein disulfide isomerase and related oxidoreductases of the endoplasmic reticulum.
Journal of Biological Chemistry.
285:(24)18155-18165.
Wong E., Maretzky T., Peleg Y., Blobel C. P. & Sagi I.
().
The functional maturation of a disintegrin and metalloproteinase (ADAM) 9, 10, and 17 requires processing at a newly identified proprotein convertase (PC) cleavage site.
The journal of Biological chemistry.
290:(19)12135-12146.
Davidi D., Shamshoum M., Guo Z., Bar‐On Y. M., Prywes N., Oz A., Jablonska J., Flamholz A., Wernick D. G., Antonovsky N., Pins B., Shachar L., Hochhauser D., Peleg Y., Albeck S., Sharon I., Mueller‐Cajar O. & Milo R.
().
Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.
The EMBO Journal.
39:(18)
Singh A., Erijman A., Noronha A., Kumar H., Peleg Y., Yarden Y. & Shifman J. M.
().
Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anti-cancer activities in lung adenocarcinoma.
Journal of Biological Chemistry.
297:(6)
Khersonsky O., Goldsmith M., Zaretsky I., Hamer-Rogotner S., Dym O., Unger T., Yona M., Fridmann-Sirkis Y. & Fleishman S. J.
().
Stable Mammalian Serum Albumins Designed for Bacterial Expression.
Journal of Molecular Biology.
435:(17)
Katzir N., Rechavi G., Cohen J., Unger T., Simoni F., Segal S., Cohen D. & Givol D.
().
'Retroposon' insertion into the cellular oncogene c-myc in canine transmissible venereal tumor.
Proceedings of the National Academy of Sciences of the United States of America.
82:(4)1054-1058.
Wong E., Cohen T., Romi E., Levin M., Peleg Y., Arad U., Yaron A., Milla M. E. & Sagi I.
().
Harnessing the natural inhibitory domain to control TNF alpha Converting Enzyme (TACE) activity in vivo.
Scientific Reports.
6.
Arfi Y., Shamshoum M., Rogachev I., Peleg Y. & Bayer E.
().
Integration of bacterial lytic polysaccharide monooxygenases into designer cellulosomes promotes enhanced cellulose degradation.
Proceedings of the National Academy of Sciences of the United States of America.
111:(25)9109-9114.
SchüTz A., Bernhard F., Berrow N., Buyel J. F., Ferreira-Da-Silva F., Haustraete J., Van Den Heuvel J., Hoffmann J. E., De Marco A., Peleg Y., Suppmann S., Unger T., Vanhoucke M., Witt S. & Remans K.
().
A concise guide to choosing suitable gene expression systems for recombinant protein production.
STAR Protocols.
4:(4)
Chill J., Nivasch R., Levy R., Albeck S., Schreiber G. & Anglister J.
().
The human interferon receptor: NMR-based modeling, mapping of the IFN-α2 binding site, and observed ligand-induced tightening.
Biochemistry.
41:(11)3575-3585.
Smock R. G., Yadid I., Dym O., Clarke J. & Tawfik D.
().
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints.
Cell.
164:(3)476-486.
Peleg Y., Vincentelli R., Collins B. M., Chen K., Livingstone E. K., Weeratunga S., Leneva N., Guo Q., Remans K., Perez K., Bjerga G. E., Larsen Ø., VaněK O., SkořEpa O., Jacquemin S., Poterszman A., Kjaer S., Christodoulou E., Albeck S., Dym O., Ainbinder E., Unger T., Schuetz A., Matthes S., Bader M., De Marco A., Storici P., Semrau M. S., Stolt-Bergner P., Aigner C., Suppmann S., Goldenzweig A. & Fleishman S. J.
().
Community-Wide Experimental Evaluation of the PROSS Stability-Design Method.
Journal of Molecular Biology.
433:(13)
Albeck S., Alzari P., Andreini C., Banci L., Berry I. M., Bertini I., Cambillau C., Canard B., Carter L., Cohen S. X., Diprose J. M., Dym O., Esnouf R. M., Felder C., Ferron F., Guillemot F., Hamer R., Ben Jelloul J. M., Laskowski R. A., Laurent T., Longhi S., Lopez R., Luchinat C., Malet H., Mochel T., Morris R. J., Moulinier L., Oinn T., Pajon A., Peleg Y., Perrakis A., Poch O., Prilusky J., Rachedi A., Ripp R., Rosato A., Silman I., Stuart D. I., Sussman J., Thierry J. -., Thompson J. D., Thornton J. M., Unger T., Vaughan B., Vranken W., Watson J. D., Whamond G. & Henrick K.
().
SPINE bioinformatics and data-management aspects of high-throughput structural biology.
Acta Crystallographica Section D-Structural Biology.
62:(10)1184-1195.
Grossman M., Tworowski D., Dym O., Lee M., Levy Y., Murphy G. & Sagi I.
().
The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function.
Biochemistry.
49:(29)6184-6192.
Ganor Y., Besser M., Ben-Zakay N., Unger T. & Levite M.
().
Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration.
Journal of Immunology.
170:(8)4362-4372.
Unger T., Jacobovitch Y., Dantes A., Bernheim R. & Peleg Y.
().
Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression.
Journal of Structural Biology.
172:(1)34-44.
Goldsmith M., Barad S., Peleg Y., Albeck S., Dym O., Brandis A., Mehlman T. & Reich Z.
().
The identification and characterization of an oxalyl-CoA synthetase from grass pea ( Lathyrus sativus L.).
RSC Chemical Biology.
3:(3)320-333.
Yifrach E., Holbrook‐Smith D., BüRgi J., Othman A., Eisenstein M., Roermund C. W., Visser W., Tirosh A., Rudowitz M., Bibi C., Galor S., Weill U., Fadel A., Peleg Y., Erdmann R., Waterham H. R., Wanders R. J. A., Wilmanns M., Zamboni N., Schuldiner M. & Zalckvar E.
().
Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions.
Molecular Systems Biology.
18:(9)
Zimhony O., Schwarz A., Raitses-Gurevich M., Peleg Y., Dym O., Albeck S., Burstein Y. & Shakked Z.
().
AcpM, the meromycolate extension Acyl carrier protein of mycobacterium tuberculosis, is activated by the 4′-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.
Biochemistry.
54:(14)2360-2371.
Selzer T., Albeck S. & Schreiber G.
().
Rational design of faster associating and tighter binding protein complexes.
Nature Structural Biology.
7:(7)537-541.
Falini G., Albeck S., Weiner S. & Addadi L.
().
Control of aragonite or calcite polymorphism by mollusk shell macromolecules.
Science.
271:(5245)67-69.
Frenkiel-Krispin D., Wolf S. G., Albeck S., Unger T., Peleg Y., Jacobovitch J., Michael Y., Daube S., Sharon M., Robinson C. V., Svergun D. I., Fass D., Tzfira T. & Elbaum M.
().
Plant transformation by Agrobacterium tumefaciens: Modulation of single-stranded DNA-VirE2 complex assembly by VirE.
Journal of Biological Chemistry.
282:(6)3458-3464.
Aricescu A. R., Assenberg R., Bill R. M., Busso D., Chang V. T., Davis S. J., Dubrovsky A., Gustafsson L., Hedfalk K., Heinemann U., Jones I. M., Ksiazek D., Lang C., Maskos K., Messerschmidt A., Macieira S., Peleg Y., Perrakis A., Poterszman A., Schneider G., Sixma T. K., Sussman J., Sutton G., Tarboureich N., Zeev-Ben-Mordehai T. & Jones E. Y.
().
Eukaryotic expression: Developments for structural proteomics.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1114-1124.
Erijman A., Dantes A., Bernheim R., Shifman J. M. & Peleg Y.
().
Transfer-PCR (TPCR): A highway for DNA cloning and protein engineering.
Journal of Structural Biology.
175:(2)171-177.
Adams E. M., Pezzotti S., Ahlers J., RüTtermann M., Levin M., Goldenzweig A., Peleg Y., Fleishman S. J., Sagi I. & Havenith M.
().
Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction.
JACS Au.
1:(7)1076-1085.
Peleg Y., Prabahar V., Bednarczyk D. & Unger T.
().
Harnessing the Profinity eXact™ System for Expression and Purification of Heterologous Proteins in E. coli.
.
33-43.
Siton O., Ideses Y., Albeck S., Unger T., Bershadsky A. D., Gov N. S. & Bernheim-Groswasser A.
().
Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.
Current Biology.
21:(24)2092-2097.
Mishra N. K., Habeck M., Kirchner C., Haviv H., Peleg Y., Eisenstein M., Apell H. J. & Karlish S. J. D.
().
Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase.
Journal of Biological Chemistry.
290:(48)28746-28759.
Bednarczyk D., Dym O., Prabahar V., Peleg Y., Pike D. H. & Noy D.
().
Fine Tuning of Chlorophyll Spectra by Protein-Induced Ring Deformation.
Angewandte Chemie-International Edition.
55:(24)6901-6905.
Oranges M., Giannoulis A., Vanyushkina A., Sirkis Y. F., Dalaloyan A., Unger T., Su X. C., Sharon M. & Goldfarb D.
().
C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.
Biophysical Journal.
Cohen S., Albeck S., Ben-Dov E., Cahan R., Firer M., Zaritsky A. & Dym O.
().
Cyt1Aa toxin: Crystal structure reveals implications for its membrane-perforating function.
Journal of Molecular Biology.
413:(4)804-814.
Yadid I., Kirshenbaum N., Sharon M., Dym O. & Tawfik D.
().
Metamorphic proteins mediate evolutionary transitions of structure.
Proceedings of the National Academy of Sciences of the United States of America.
107:(16)7287-7292.
Israeli H., Degtjarik O., Fierro F., Chunilal V., Gill A. K., Roth N. J., Botta J., Prabahar V., Peleg Y., Chan L. F., Ben-Zvi D., Mccormick P. J., Niv M. Y. & Shalev-Benami M.
().
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.
Science (American Association for the Advancement of Science).
372:(6544)808-814.
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Acta Crystallographica Section D: Biological Crystallography.
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Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution.
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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.
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Do Src kinase and caveolin interact directly with Na,K-ATPase?.
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The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition.
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Evolution of CPEB4 Dynamics Across its Liquid–Liquid Phase Separation Transition.
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Evaluation of direct and cooperative contributions towards the strength of buried hydrogen bonds and salt bridges.
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Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.
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Monitoring the Conformation of the Sba1/Hsp90 Complex in the Presence of Nucleotides with Mn(II)-Based Double Electron–Electron Resonance.
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A Molecular Lid Mechanism of K+ Channel Blocker Action Revealed by a Cone Peptide.
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Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels.
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Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
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Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.
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International Journal of Cancer.
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Current Biology.
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Proceedings of the National Academy of Sciences of the United States of America.
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PLoS ONE.
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The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallographica Section D: Structural Biology.
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Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators.
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Acta Crystallographica Section D: Biological Crystallography.
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Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill.
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Efficient targeted degradation via reversible and irreversible covalent PROTACs.
Journal of the American Chemical Society.
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Conkunitzin-C2 from Conus consors induces an incomplete block of the Shaker K+ channel using a unique mode of action.
Biophysical Journal.
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