Kolodkin-Gal lab, Assembly and Disassembly of Microbial Biofilms


Microbes use a variety of mechanisms to
coordinate activity within a community to
accomplish complex multi-cellular
processes. Understanding
bacterial-unique multi-cellular
communities, such as biofilms, is highly
significant from clinical, agricultural and
ecological perspectives, e.g, biofilms
formed by various pathogens play a
critical role in device-related infections,
infective endocarditis, urinary tract
infections, acute septic arthritis and plant

Our lab explores key questions
in bacterial development:

  • What is the interplay between
    chemical and biological signals
    involved in the living within
    bacterial multicellular
  • How can bacterial cells transit
    back to an individual life-style?