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May 01-31, 2016

  • Date:25WednesdayMay 2016

    Sexually dimorphic neuronal connectivity established by sex-specific synapse pruning in C. elegans

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    Time
    14:00 - 15:00
    Location
    Raoul and Graziella de Picciotto Building for Scientific and Technical Support
    Lobby
    Lecturer
    Dr. Meital Oren-Suissa
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY
    Organizer
    Department of Immunology and Regenerative Biology
    Contact
    Lecture
  • Date:26ThursdayMay 2016

    Magnetic Resonance Seminar

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    Time
    09:30
    Title
    Magnetic Molecular Beams - a non-conventional approach for hyper sensitive NMR
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Gil Alexandrowicz
    Schulich Faculty of Chemistry, Technion
    Organizer
    Department of Chemical and Biological Physics
    Contact
    Lecture
  • Date:26ThursdayMay 2016

    Exploring Flatland

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Auditorium
    Lecturer
    Andre Geim
    Manchester
    Organizer
    Faculty of Physics
    Contact
    DetailsShow full text description of 11:00 – coffee, tea, and more...»
    11:00 – coffee, tea, and more
    AbstractShow full text abstract about Following the advent of graphene, many other one-atom or one...»
    Following the advent of graphene, many other one-atom or one-molecule thick crystals have been isolated and investigated. These two-dimensional crystals have become one of the hottest topics in materials science and condensed matter physics. Furthermore, isolated atomic planes can now be reassembled back into three-dimensional structures and crystals made layer by layer in a designer sequence. I will provide a brief, lowbrow introduction to graphene, trying to explain why this material has attracted so much attention, and then overview our progress in making new assemblies from available atomic planes in order to illustrate how rich in phenomena and application this research field is.
    Colloquia
  • Date:26ThursdayMay 2016

    Single-molecule views of eukaryotic DNA mismatch repair

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    Time
    14:00
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Prof. Ilya Finkelstein
    Department of Molecular Biosciences & ICMB University of Texas at Austin
    Organizer
    Department of Chemical and Structural Biology
    Contact
    Lecture
  • Date:27FridayMay 2016

    Nathan's Friends - Argentine tango

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    Time
    20:00
    Location
    Michael and Anna Wix Auditorium
    Contact
    Cultural Events
  • Date:28SaturdayMay 2016

    "Set el chbayeb Ima" - Iraqi show

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    Time
    20:30 - 22:00
    Location
    Michael and Anna Wix Auditorium
    Contact
    Cultural Events
  • Date:29SundayMay 201610FridayJune 2016

    Cosmological Probes of Fundamental Physics

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    Time
    All day
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Chairperson
    Kfir Blum
    Contact
    Conference
  • Date:29SundayMay 2016

    G-INCPM-Special Seminar - Yael Malkinson Weiss, MD PhD, Executive Director Business Development, Ultragenyx Pharmaceutical, Novato CA - "Developing therapies for rare genetic diseases: weighing traditional versus novel therapeutic modalities"

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    Time
    11:00 - 12:30
    Location
    Nancy and Stephen Grand Israel National Center for Personalized Medicine
    Auditorium
    Lecturer
    Yael Malkinson Weiss, MD PhD
    Executive Director Business Development, Ultragenyx Pharmaceutical, Novato CA
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Developing therapies for the treatment of rare genetic disea...»
    Developing therapies for the treatment of rare genetic disease is frequently perceived to be simpler and with a lower risk than that associated with larger indications. This perception stems from the fact that many of these are monogenic, with predictable genetic effects and clear mechanisms, thus it should be straightforward to replace the defective protein. Since the diseases are usually severe the benefit is large, and in many cases, the rarer the disease, the smaller the clinical trials that are required for registration are.
    However, there are over 7,000 genetic diseases with an even larger number of genes affected. The initial approach of protein replacement therapies can be successful but is limited to a relatively small diseases in which the defective proteins are localized in a subset of cellular organelles to which therapeutic proteins will naturally target (lysosome for example). Most of the diseases treatable with traditional protein replacement are becoming very crowded for how small the treatable patient population is. Thus - other solutions need to be considered for the thousands of diseases for which direct proteins replacement is not a viable approach.
    Ultragenyx is a biotech company focused on development of therapies for rare genetic diseases. The company’s approach to building its pipeline and deciding how and when to include traditional (protein replacement therapies, small molecules) or new (nucleic acid based therapies) therapeutic modalities will be presented and examples will be discussed.

    Lecture
  • Date:29SundayMay 2016

    The ins and outs of subaerial lithotrophic biofilm in arid and hyper-arid environments

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    Time
    11:00
    Location
    Sussman Family Building for Environmental Sciences
    M. Magaritz Seminar Room
    Lecturer
    Nimrod Wieler
    Department of Environmental Hydrology & Microbiology Ben-Gurion University of the Negev
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    AbstractShow full text abstract about Rock surfaces support microbial communities that may be invo...»
    Rock surfaces support microbial communities that may be involved in weathering processes. In arid and hyper-arid environments microbes dominate rock surfaces and were linked to weathering because the scarcity of water excludes classical mechanisms that erode rocks. We studied subaerial biofilms coating arid rocks, focusing on sedimentary rocks that feature comparable weathering morphologies but different lithologies. We hypothesized that weathering is fashioned by salt erosion and mediated by biofilms that play dual roles: stabilizing the rock surfaces by coating, and enhancing salt crystallization by preventing rapid desiccation (thus mitigating and facilitating erosion processes, respectively). We used a combination of microbial and geological techniques to characterize the rocks morphologies and their subaerial biofilms. Deep sequencing and microscopy analyses suggest that bacterial diversity is low, dominated by Proteobacteria, Cyanobacteria and Actinobacteria. Together these phyla formed laminar biofilms that secrete extracellular polymeric substances to aggregate microfabrics and mitigate desiccation, reducing water loss by over 40%. The biofilm was detected only in rocks exposed to the atmosphere, present distinct architecture and burrowed up to 9 mm beneath the surface, protected by sedimentary deposits. A closer inspection revealed that the composition of the biofilm was tightly linked to dust bacterial communities but distinct from soil communities. Moreover, the biofilm composition changed according to the rock location rather than its’ lithology, suggesting that microclimate (dew, relative humidity and radiation) play an important role in arid weathering. Our results contradict common dogmas that considered biofilms as degrading agents and propose their role as mitigators of geomorphic processes.
    Lecture
  • Date:29SundayMay 2016

    A systematic view on Influenza induced host shut-off

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    Time
    13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Julie Tai
    Noam Stern-Ginossar's group, Dept. of Molecular Genetics, WIS
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:29SundayMay 2016

    The Simple Physics Behind Energy Use

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    Time
    13:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Peter Rez
    Department of Physics, Arizona State University, USA
    Organizer
    Feinberg Graduate School
    Alternative Sustainable Energy Research Initiative (AERI)
    Contact
    DetailsShow full text description of Gathering & refreshments at 12:40...»
    Gathering & refreshments at 12:40
    Lecture
  • Date:29SundayMay 2016

    Quantitative investigation of birdsong: from learning to performance

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    Time
    13:00
    Location
    Dannie N. Heineman Laboratory
    Drory Auditorium
    Lecturer
    Prof. Ofer Tchernichovski
    Department of Psychology Hunter College, NYC
    Organizer
    Clore Center for Biological Physics
    Biological Physics Group
    Contact
    DetailsShow full text description of Sandwiches at 12:45...»
    Sandwiches at 12:45
    AbstractShow full text abstract about • Music maintains a characteristic balance between repetitio...»
    • Music maintains a characteristic balance between repetition and novelty. I will present evidence for a similar balance in singing performances of free-living Australian pied butcherbirds.
    • While acquiring motor skills, such as courtship songs and dances, animals must match their performance to a desired target. However, because both the structure and the temporal position of individual gestures are adjustable, the number of possible motor transformations increases exponentially with sequence length, and searching for the optimal transformation quickly becomes computationally intractable. We show how zebra finches cope with the computational complexity of song learning.
    Lecture
  • Date:29SundayMay 2016

    Antihydrogen - a tool to study matter-antimatter symmetry in the laboratory

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    Time
    14:00
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Drory Auditorium
    Lecturer
    Eberhard Widmann
    President of the Austrian Physical Society Director, Stefan Meyer Institute for Subatomic Physics, Austrian Academy of Sciences
    Organizer
    Department of Particle Physics and Astrophysics
    Special Seminar
    Contact
    AbstractShow full text abstract about Antihydrogen, the bound state of an antiproton and a positro...»
    Antihydrogen, the bound state of an antiproton and a positron, is the simplest atom consisting purely of antimatter. Its matter counterpart, hydrogen, is one of the best studied atomic systems in physics. Thus comparing the spectra of hydrogen and antihydrogen offers some of the most sensitive tests of matter-antimatter symmetry. Furthermore, the availability of neutral antimatter offers for the first time a precise measurement of its gravitational interaction that was so far not possible due to the dominance of the electro-magnetic interaction for charged antiparticles.

    The formation and experimental investigation of antihydrogen is the main physics goal of several col-laborations at the Antiproton Decelerator of CERN. The ASACUSA collaboration is pursuing a meas-urement of the ground-state hyperfine structure of antihydrogen in an atomic beam, a quantity which was measured in hydrogen using a maser to a relative precision of 10^{-12}. The AEgIS collaboration aims at using an ultra-cold beam of antihydrogen atoms and a classical moiré deflectometer to determine the gravitational interaction between matter and antimatter in a first step to percent level precision.

    After a first production of cold antihydrogen in 2002 and a first trapping in 2010 the experiments are still in the process of optimizing the antihydrogen production from trapped antiprotons and positrons. The status and prospect of these experiments will be reviewed.
    Lecture
  • Date:29SundayMay 2016

    Unraveling unconventional role for astroglial connexins in synaptic strength and memory

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    Time
    15:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Nathalie Rouach
    CIRB, College de France, Paris
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Astrocytes play active roles in brain physiology by dynamic ...»
    Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellular and molecular mechanisms were unknown. We will show here in mice that connexin 30 controls hippocampal excitatory synaptic transmission through modulation of astroglial glutamate transport, which directly alters synaptic glutamate levels. Unexpectedly, we found that connexin 30 regulated cell adhesion and migration and that connexin 30 modulation of glutamate transport, occurring independently of its channel function, was mediated by morphological changes controlling insertion of astroglial processes into synaptic clefts. By setting excitatory synaptic strength, connexin 30 plays an important role in long-term synaptic plasticity and in hippocampus-based contextual memory. Taken together, these results establish connexin 30 as a critical regulator of synaptic strength by controlling the synaptic location of astroglial processes.
    Lecture
  • Date:29SundayMay 2016

    Braginsky Center for the Interface between the Sciences and the Humanities

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    Time
    15:30
    Title
    Back to the Future: Recovering “The Age of Wonder”
    Location
    Dolfi and Lola Ebner Auditorium
    Lecturer
    Prof. David K. Campbell
    Boston University
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about In his remarkable and inspiring book “The Age of Wonder,” Ri...»
    In his remarkable and inspiring book “The Age of Wonder,” Richard Holmes describes the synergistic links between the sciences and humanities among (in particular) the English intellectuals in the period 1770-1830. “Natural philosophers” like Sir Humphrey Davy had regular interactions with poets like Samuel Taylor Coleridge, and authors like Mary Shelly wrote of dystopias that could result from the misapplication of science and technology. Modern intellectuals, contemplating the current clearly apparent divide between the humanities and the sciences, tend to look at this “age of wonder” through rose-colored glasses and to long for its return. But is this yearning realistic? In our increasingly complex and specialized world, can we truly expect to recover the close bond between these distinct ways of knowing the world? Can we construct an interdisciplinary technological humanism that meaningfully links the sciences and the humanities?

    In this talk I attempt to provide limited and subjective answers to these questions and to describe general developments and trends that I believe may give hope that we can indeed recover the “age of wonder.”
    Lecture
  • Date:30MondayMay 2016

    Multi-level scalable proteomic interrogation of intact biological systems

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    Time
    10:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Prof. Kwanghun Chung
    Department of Chemical Engineering Institute for Medical Engineering and Science (IMES)Picower Institute for Learning and Memory Massachusetts Institute of Technology http://www.chunglab.org/
    Organizer
    Department of Brain Sciences
    Contact
    DetailsShow full text description of Lecture co-hosted by the Neurobiology Department and the Opt...»
    Lecture co-hosted by the Neurobiology Department and the Optical Imaging Club
    Lecture
  • Date:30MondayMay 2016

    "Chemical Publishing in the 21st Century:Perspectives of a JACS Editor"

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    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Peter Stang
    Department of Chemistry, University of Utah
    Organizer
    Faculty of Chemistry
    Contact
    Colloquia
  • Date:30MondayMay 2016

    The diphoton excess at the LHC

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    Time
    11:00
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Drory Auditorium
    Lecturer
    Liron Barak
    CERN
    Organizer
    Department of Particle Physics and Astrophysics
    Special Seminar
    Contact
    AbstractShow full text abstract about “Early results from the Run-II of the Large Hadron Collider ...»
    “Early results from the Run-II of the Large Hadron Collider were recently presented by the ATLAS and CMS experiments. They show hints of an excess in the diphoton mass spectrum near 750 GeV. While these hints might turn out to be statistical fluctuations, they could also be first indications of physics beyond the Standard Model. I will explain in detail the experimental procedures that led to these exciting results. I will further describe the strategy in which we intend to investigate this excess in the near future and either reject or confirm the discovery of new physics.”
    Lecture
  • Date:30MondayMay 2016

    Active DNA Demethylation in Development and Cancer

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    Time
    12:00 - 13:30
    Location
    Camelia Botnar Building
    Auditorium
    Lecturer
    Prof. Alfonso Bellacosa
    Cancer Epigenetics and Cancer Biology Programs, Fox Chase Cancer Center, Philadelphia USA
    Organizer
    Department of Biomolecular Sciences
    Contact
    Lecture
  • Date:30MondayMay 2016

    Geometric Heat Engines Without Power-Efficiency Tradeoff

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    Time
    14:15
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Room A
    Lecturer
    OREN RAZ
    UNIVERSITY OF MARYLAND
    Organizer
    Department of Physics of Complex Systems
    Statistical Physics Seminar
    Contact
    AbstractShow full text abstract about Thermodynamics places a limit on the efficiency of heat engi...»
    Thermodynamics places a limit on the efficiency of heat engines, but not on their output power or on how the power and efficiency change with the engine’s cycle time. In the talk I will present a geometrical description of the power and efficiency as a function of the cycle time, applicable to an important class of heat engine models. This geometrical description is used to design engine protocols that attain both the maximal power and maximal efficiency at the fast driving limit. Furthermore, using this method, we also prove that no protocol can exactly attain the Carnot efficiency at nonzero power.

    Ref: PRL 116, 160601 (2016)

    Lecture

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