Active space experiments study plasma processes induced by different energy releases in space (plasma clouds, beams of energetic particles, powerful radio-emissions). High altitude nuclear explosions can be considered from this point of view. A number of effects of geo- and astrophysical importance were observed during the space tests of nuclear weapon conducted in 50s – early 60s. Development of Rayleigh-Taylor instability, diamagnetic cavity formation, artificial aurora are considered. There is certain evidence that transient luminous events (sprites) were observed during the Starfish test in 1962.