COVID-19 in pregnancy

The objective of this study is to better understand the state and severity of infection during pregnancy and its effect on fetal development and neonatal outcome. The goal is to provide answers for the following questions:

  1. Are asymoptomaic women infected with SARS-Cov-2 at high risk for delivery complications or fetal developmental disorders?
  2. Does the time of infection affect outcome?
  3. Is there vertical transmission for early pregnancy infection?
  4. Is there evidence for fetal/placenta pathology?
  5. Is ACE2 expressed by the placenta relevant for pregnancy outcome after infection?

Preprints and publications

Efficient Maternal to Neonatal transfer of SARS-CoV-2 and BNT162b2 antibodies

Collaborating partners

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Mt. Scopus, Jerusalem, Israel

Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001 Israel

Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food & Environment, The Hebrew University of Jerusalem P.O. Box 12, Rehovot 76100, Israel

Department of Obstetrics and Gynecology, Wolfson Medical Center, Holon; affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva; affiliated to Sackler Faculty of Medicine, Tel Aviv University

The Hillel Yaffe Medical Center, Hadera, Israel, the Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.

Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel

Department of Obstetrics and Gynecology, Emek Medical Center, Afula, Israel affiliated with Rappaport Faculty of Medicine, Technion, Haifa, Israel.

Department of Immunology, Weizmann Institute of Science, Rehovot 7610001 Israel

Lis Hospital for Women, Tel Aviv Sourasky Medical Center, Tel  Aviv, Israel; affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
 

Supported by a research grant from the ISF KillCorona Program:

  • Weizmann Institute of Science  Michal Neeman
  • Wolfson Medical Center/ TAU    Michal Kovo
  • Hadassah Medical Center/ HUJ    Simcha Yagel
  • Sourasky Medical Center/ TAU    Ariel Many

Supported by a research grant from the Fondazione Henry Krenter