Vascular remodelling in reproduction and development

The ovary

• Genetic and Pharmacological Modulation of Akt1 for Improving Ovarian Graft Revascularization in a Mouse Model
  Cohen Y., Dafni H., Avni R., Fellus L., Bochner F., Rotkopf R., Raz T., Benjamin L. E., Walsh K. & Neeman M. (2016) Biology of Reproduction. 94, 1, p. 14 14.
• A Novel Intravital Imaging Window for Longitudinal Microscopy of the Mouse Ovary
  Bochner F., Fellus-Alyagor L., Kalchenko V. (., Shinar S. & Neeman M. (2015) Scientific Reports. 5, 12446.
• Ovarian Dendritic Cells Act as a Double-Edged Pro-Ovulatory and Anti-Inflammatory Sword
  Cohen-Fredarow A., Tadmor A., Raz T., Meterani N., Addadi Y., Nevo N., Solomonov I., Sagi I., Mor G., Neeman M. & Dekel N. (2014) Molecular Endocrinology. 28, 7, p. 1039-1054
• In search of signaling pathways critical for ovarian graft reception: Akt1 is essential for long-term survival of ovarian grafts
  Cohen Y., Dafni H., Avni R., Raz T., Biton I., Hemmings B. & Neeman M. (2014) Fertility and Sterility. 101, 2, p. 536-+
• Reducing ischaemic damage in rodent ovarian xenografts transplanted into granulation tissue
  Israely T., Nevo N., Harmelin A., Neeman M. & Tsafiri A. (2006) Human Reproduction. 21, 6, p. 1368-1379
• Angiogenesis in ectopic ovarian xenotransplantation: Multiparameter characterization of the neovasculature by dynamic contrast-enhanced MRI
  Israely T., Dafni H., Nevo N., Tsafriri A. & Neeman M. (2004) Magnetic Resonance in Medicine. 52, 4, p. 741-750
• Vascular remodeling and angiogenesis in ectopic ovarian transplants: A crucial role of pericytes and vascular smooth muscle cells in maintenance of ovarian grafts
  Israely T., Dafni H., Granot D., Nevo N., Tsafriri A. & Neeman M. (2003) Biology of Reproduction. 68, 6, p. 2055-2064
• Non-invasive analysis of rat ovarian angiogenesis by MRI
  Tempel-Brami C. & Neeman M. (2002) Molecular and Cellular Endocrinology. 187, 2-Jan, p. 19-22 
• Spatial and temporal modulation of perfusion in the rat ovary measured by arterial spin labeling MRI
  Tempel C. & Neeman M. (1999) Jmri-Journal Of Magnetic Resonance Imaging. 9, 6, p. 794-803
• Perfusion of the rat ovary: Application of pulsed arterial spin labeling MRI
  Tempel C. & Neeman M. (1999) Magnetic Resonance in Medicine. 41, 1, p. 113-123
• Regulation of angiogenesis by hypoxic stress: From solid tumours to the ovarian follicle
  Neeman M., Abramovitch R., Schiffenbauer Y. & Tempel C. (1997) International Journal of Experimental Pathology. 78, 2, p. 57-70
• MODULATION OF WATER DIFFUSION DURING GONADOTROPIN-INDUCED OVULATION - NMR MICROSCOPY OF THE OVARIAN FOLLICLE
  TEMPEL C., SCHIFFENBAUER Y., Meir G. & Neeman M. (1995) Magnetic Resonance in Medicine. 34, 2, p. 213-218

Embryo implantation

• Blastocyst implantation failure relates to impaired translational machinery gene expression
  Plaks V., Gershon E., Zeisel A., Jacob-Hirsch J., Neeman M., Winterhager E., Rechavi G., Domany E. & Dekel N. (2014) Reproduction. 148, 1, p. 87-98
• Implantation disorder related to impaired translation in the oocyte and in the resulting embryo
  Zeisel A., Plaks V., Gershon E., Winterhager E., Neeman M., Domany E. & Dekel N. (2009) Developmental Biology. 331, 2, p. 419-419
• Uterine DCs are crucial for decidua formation during embryo implantation in mice
  Plaks V., Birnberg T., Berkutzki T., Sela S., BenYashar A., Kalchenko V., Mor G., Keshet E., Dekel N., Neeman M. & Jung S. (2008) Journal of Clinical Investigation. 118, 12, p. 3954-3979
• MRI analysis of angiogenesis during mouse embryo implantation
  Plaks V., Kalchenko V. (., Dekel N. & Neeman M. (2006) Magnetic Resonance in Medicine. 55, 5, p. 1013-1022

The placenta

• Molecular pathways of senescence regulate placental structure and function
  Gal H., Lysenko M., Stroganov S., Vadai E., Youssef S. A., Tzadikevitch-Geffen K., Rotkopf R., Biron-Shental T., de Bruin A., Neeman M. & Krizhanovsky V. (2019) EMBO Journal. 38, 18, 100849. 
• Placental physiology monitored by hyperpolarized dynamic ¹³C magnetic resonance
  Markovic S., Fages A., Roussel T., Hadas R., Brandis A., Neeman M. & Frydman L. (2018) Proceedings of the National Academy of Sciences of the United States of America. 115, 10, p. E2429-E2436
• MR Imaging-derived OxygenHemoglobin Dissociation Curves and Fetal-Placental OxygenHemoglobin Affinities
  Avni R., Golani O., Akselrod-Ballin A., Cohen Y., Biton I., Garbow J. R. & Neeman M. (2016) Radiology. 280, 1, p. 68-77 26780539.
• Functional MRI of the placenta - From rodents to humans
  Avni R., Neeman M. & Garbow J. (2015) Placenta. 36, 6, p. 615-622
• Major mouse placental compartments revealed by diffusion-weighted MRI, contrast-enhanced MRI, and fluorescence imaging
  Solomon E., Avni R., Hadas R., Raz T., Garbow J. R., Bendel P., Frydman L. & Neeman M. (2014) Proceedings of the National Academy of Sciences of the United States of America. 111, 28, p. 10353-10358
• The Hemodynamic Basis for Positional- and Inter-Fetal Dependent Effects in Dual Arterial Supply of Mouse Pregnancies
  Raz T., Avni R., Addadi Y., Cohen Y., Jaffa A. J., Hemmings B., Garbow J. R. & Neeman M. (2012) PLoS One. 7, 12,
• Unique in utero identification of fetuses in multifetal mouse pregnancies by placental bidirectional arterial spin labeling MRI
  Avni R., Raz T., Biton I. E., Kalchenko V., Garbow J. R. & Neeman M. (2012) Magnetic Resonance in Medicine. 68, 2, p. 560-570
• Functional Phenotyping of the Maternal Albumin Turnover in the Mouse Placenta by Dynamic Contrast-Enhanced MRI
  Plaks V., Sapoznik S., Berkovitz E., Haffner-Krausz R., Dekel N., Harmelin A. & Neeman M. (2011) Molecular Imaging and Biology. 13, 3, p. 481-492
• Survival and Size Are Differentially Regulated by Placental and Fetal PKBalpha/AKT1 in Mice
  Plaks V., Berkovitz E., Vandoorne K., Berkutzki T., Damari G. M., Haffner R., Dekel N., Hemmings B. A., Neeman M. & Harmelin A. (2011) Biology of Reproduction. 84, 3, p. 537-545
• Vascular function and growth is differentially regulated by fetal and placental PKBalpha/Akt1 in a gene dosage dependent manner: Non-invasive dynamic contrast enhanced MRI
  Plaks V., Berkovitz E., Vandoorne K., Sharir A., Zelzer E., Wehrli F. W., Dekel N., Hemmings B. A., Neeman M. & Harmelin A. (2009) Developmental Biology. 331, 2, p. 499-499
• Cloprostenol, a prostaglandin F-2 alpha analog, induces hypoxia in rat placenta: BOLD contrast MRI
  Girsh E., Plaks V., Gilad A. A., Nevo N., Schechtman E., Neeman M. & Dekel N. (2007) NMR in Biomedicine. 20, 1, p. 28-39