Potent antitumor activity of anti-HER2 antibody-topoisomerase I inhibitor conjugate based on self-immolative dendritic dimeric-linker

Liubomirski Y., Tiram G., Scomparin A., Gnaim S., Das S., Gholap S., Ge L., Yeini E., Shelef O., Zauberman A., Berger N., Kalimi D., Toister-Achituv M., Schröter C., Dickgiesser S., Tonillo J., Shan M., Deutsch C., Sweeney-Lasch S., Shabat D. & Satchi-Fainaro R. (2024) Journal of Controlled Release. 367, p. 148-157


An electroaffinity labelling platform for chemoproteomic-based target identification

Kawamata Y., Ryu K. A., Hermann G. N., Sandahl A., Vantourout J. C., Olow A. K., Adams L. T. A., Rivera-Chao E., Roberts L. R., Gnaim S., Nassir M., Oslund R. C., Fadeyi O. O. & Baran P. S. (2023) Nature Chemistry. 15, 9, p. 1267-1275


Cobalt-electrocatalytic HAT for functionalization of unsaturated C–C bonds

Gnaim S., Bauer A., Zhang H. J., Chen L., Gannett C., Malapit C. A., Hill D. E., Vogt D., Tang T., Daley R. A., Hao W., Zeng R., Quertenmont M., Beck W. D., Kandahari E., Vantourout J. C., Echeverria P. G., Abruna H. D., Blackmond D. G., Minteer S. D., Reisman S. E., Sigman M. S. & Baran P. S. (2022) Nature. 605, 7911, p. 687-695

Modular Access to Diverse Chemiluminescent Dioxetane-Luminophores through Convergent Synthesis

Gnaim S., Gholap S. P., Ge L., Das S., Gutkin S., Green O., Shelef O., Hananya N., Baran P. S. & Shabat D. (2022) Angewandte Chemie - International Edition. 61, 22, e202202187.


Self-Immolative Polymers: An Emerging Class of Degradable Materials with Distinct Disassembly Profiles

Shelef O., Gnaim S. & Shabat D. (2021) Journal of the American Chemical Society. 143, 50, p. 21177-21188

Electrochemically driven desaturation of carbonyl compounds

Gnaim S., Takahira Y., Wilke H. R., Yao Z., Li J., Delbrayelle D., Echeverria P. G., Vantourout J. C. & Baran P. S. (2021) Nature Chemistry. 13, 4, p. 367-372

Carbonyl Desaturation: Where Does Catalysis Stand?

Gnaim S., Vantourout J. C., Serpier F., Echeverria P. G. & Baran P. S. (2021) ACS Catalysis. 11, 2, p. 883-892


Light emission enhancement by supramolecular complexation of chemiluminescence probes designed for bioimaging

Gnaim S., Scomparin A., Eldar-Boock A., Bauer C. R., Satchi-Fainaro R. & Shabat D. (2019) Chemical Science. 10, 10, p. 2945-2955

Chemiluminescence molecular probe with a linear chain reaction amplification mechanism

Gnaim S. & Shabat D. (2019) Organic and Biomolecular Chemistry. 17, 6, p. 1389-1394


Direct Real-Time Monitoring of Prodrug Activation by Chemiluminescence

Gnaim S., Scomparin A., Das S., Blau R., Satchi-Fainaro R. & Shabat D. (2018) Angewandte Chemie - International Edition. 57, 29, p. 9033-9037

The emergence of aqueous chemiluminescence: New promising class of phenoxy 1,2-dioxetane luminophores

Gnaim S., Green O. & Shabat D. (2018) Chemical Communications. 54, 17, p. 2073-2085


Near-Infrared Dioxetane Luminophores with Direct Chemiluminescence Emission Mode

Green O., Gnaim S., Blau R., Eldar-Boock A., Satchi-Fainaro R. & Shabat D. (2017) Journal of the American Chemical Society. 139, 37, p. 13243-13248

Self-Immolative Chemiluminescence Polymers: Innate Assimilation of Chemiexcitation in a Domino-like Depolymerization

Gnaim S. & Shabat D. (2017) Journal of the American Chemical Society. 139, 29, p. 10002-10008


Tagging the Untaggable: A Difluoroalkyl-Sulfinate Ketone-Based Reagent for Direct C-H Functionalization of Bioactive Heteroarenes

Gnaim S., Scomparin A., Li X., Baran P. S., Rader C., Satchi-Fainaro R. & Shabat D. (2016) Bioconjugate Chemistry. 27, 9, p. 1965-1971

Dendritic, Oligomeric, and Polymeric Self-Immolative Molecular Amplification

Roth M. E., Green O., Gnaim S. & Shabat D. (2016) Chemical Reviews. 116, 3, p. 1309-1352