PUBLICATIONS

Publications from the Abramson Lab (2011-present):

C Bornstein, S Nevo, A Giladi, N Kadouri, M Pouzolles, F Gerbe, E David, A Machado, A Chuprin, B Tóth, O Goldberg, S Itzkovitz, N Taylor, P Jay, VS Zimmermann, J Abramson*, I Amit*: Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells; Nature, 2018 Jul;559(7715):622-626 (*equal contribution)

A Avin, M Levy, Z Porat & J Abramson: Quantitative analysis of protein-protein interactions and post-translational modifications in rare immune populations. Nature Commiunications, 2017, 8(1):1524.

J Abramson & G Anderson: Thymic Epithelial Cells. Annual Review of Immunology 2017 35 (1); link 

Y Herzig, S Nevo, C Bornstein, MR Brezis, S Ben-Hur, A Shkedy, M Eisenberg, B Levi, M Delacher, Y Goldfarb, E David L Weinberger, S Viukov, S Ben-Dor, M Giraud, JH Hanna, A Breiling, F Lyko, I Amit, M Feuerer & J Abramson: Transcriptional programs that control expression of the autoimmune regulator gene Aire;  Nature Immunology, 2017, 19(2); DOI: 10.1038/ni.3638

M Danan-Gotthold, C Guyon, M Giraud, EY Levanon* & J Abramson*. Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells; Genome Biology, 2016 17:234

Y Goldfarb, N Kadouri, B Levi, A Sela, Y Herzig, R Cohen, A Hollenberg, J Abramson: HDAC3 is a master regulator of mTEC development; Cell Rep.  2016; 15(3):651-65

J Abramson, ES Husebye: Autoimmune Regulator and self-tolerance - molecular and clinical aspects (Review); Immunol Rev. 2016; 271(1):127-40

J Abramson, Y Goldfarb: AIRE: From promiscuous molecular partnerships to promiscuous gene expression (Review), Eur J Immunol. 2016; 46(1):22-33.

A Chuprin, A Avin, Y Goldfarb, Y Herzig, B Levi, A Jacob, A Sela, S Katz, M Grossman, C Guyon, M Rathaus, HY Cohen, I Sagi, M Giraud, MW McBurney, ES Husebye, J Abramson: The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance, Nature Immunology, 2015, Jul;16(7): 737-45

BE Oftedal, A Hellesen, MM Erichsen, E Bratland, A Vardi, J Perheentupa, EH Kemp, T Fiskerstrand, MK Viken, AP. Weetman, SJ Fleishman, S Banka, WG Newman, WAC Sewell, LS Sozaeva, T Zayats, K Haugarvoll, EM Orlova, J Haavik,  S Johansson, PM Knappskog, K Løvås, ASB Wolff, J Abramson*, ES Husebye*: Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases, Immunity, 2015, Jun 16;42(6):1185-96. (*equal contribution)

Publications from postdoc (2005-2010):

M. Giraud, H Yoshida, J. Abramson, PB. Rahl, RA Young, D Mathis, and C Benoist:Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells, PNAS, 2012, 109(2):535-40
 
J. Abramson, M. Giraud, C. Benoist, and D. Mathis: Aire’s partners in the molecular control of immunological tolerance, Cell, 2010, 140(1); 123-135
 
AS. Koh, AJ. Kuo, SY. Park, P. Cheung, J. Abramson, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, C. Benoist, and D. Mathis: Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity, PNAS; 2008; 105(41):15878-83
 
D. Gray, J. Abramson, C. Benoist, and D. Mathis: Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire, J. Exp. Med., 2007; 204(11): 2521 – 2528
 

Commentaries and previews on published work:

Part Peterson: Sirt-ainly Aire; Nat Immunol. 2015 Jun 18;16(7):680-1; commentary on Chuprin A et al, Nat Immunol 2015

MS Anderson, JL Casanova: More than Meets the Eye: Monogenic Autoimmunity Strikes Again; Immunity 2015 Jun 16;42(6):986-8; commentary on Oftedal B et al, Immunity 2015

Bruno Kyewski and Part Peterson: Aire, Master of Many Trades; Cell, 2010, 140(1); 24-26; commentary on: J. Abramson, et al, Cell, 2010

 
Kirsty Minton; Tolerance: How AIRE wakes up sleepy genes; Nature Reviews Immunology, 2010, 10 (2), 87-87; commentary on: J. Abramson, et al, Cell, 2010
 
Towns R and Pietropaolo M; Aire's partnerships: an answer for many questions and new questions in search of answers; Pediatric Diabetes, 2010, 11(2):85-7 commentary on: J. Abramson, et al, Cell, 2010
 
Connie Lee: Avoiding Autoimmunity with Aire; Cell, 2010, 140(1); online: http://download.cell.com/mmcs/journals/0092-8674/PIIS009286740901616X.mm... paper clip with an audio interview on: Abramson, et al, Cell, 2010