Publications | Department of Molecular Cell Biology

2026

Co-Biotics - Dual modulation of the host and the microbiota

Versalovic J., Segal E., Mayer E. A., Gibson G. R., Morelli L. & Reid G. (2026), Trends in Food Science and Technology. 169, 105561

Localization of Asgard archaeal ESCRT proteins to eukaryotic cellular structures

Naripogu K. B., Tee Y. H., Senju Y., Bershadsky A. & Robinson R. C. (2026), Biochemical and Biophysical Research Communications. 802, 153301

A foundation model for continuous glucose monitoring data

Lutsker G., Sapir G., Shilo S., Merino J., Godneva A., Greenfield J. R., Samocha-Bonet D., Dhir R., Gude F., Mannor S., Meirom E., Xing E. P., Chechik G., Rossman H. & Segal E. (2026), Nature

The Highly Localized Interaction between Neurofascin-186 and Gliomedin Promotes Subcellular Innervation by the Chandelier Cell

Hayano Y., Ishino Y., Bhat M. A., Peles E. & Taniguchi H. (2026), Journal of Neuroscience. 46, 2, e04642520
Submitted Version

N1-Methylpseudouridine directly modulates translation dynamics

Rozman B., Broennimann K., Rajan K. S., Nachshon A., Saha C., Arazi T., Mohan V., Geiger T., Wollner C. J., Richner J. M., Westhof E., Yonath A., Bashan A. & Stern-Ginossar N. (2026), Nature

Personalized dietary feedback mediates the association of dietary self-monitoring adherence and weight loss: a post-hoc analysis of the Personal Diet Study

Berube L. T., Wang C., Curran M., Pompeii M. L., Hu L., Barua S., Li H., St-Jules D. E., Schoenthaler A., Segal E., Bergman M. & Popp C. J. (2026), Journal of Nutrition, 101364

Design of bacterial DNT sensors based on computational models

Bahiri Elitzur S., Shpigel E., Katzir I., Alon U., Belkin S. & Tuller T. (2026), Nucleic Acids Research. 54, 1, gkaf1482

Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinsons disease: a randomized double-blind prospective study

Hegelmaier T., Duscha A., Desel C., Fuchs S., Shapira M., Amidror S., Shan Q., Stangl G. I., Hirche F., Kempa S., Maifeld A., Würtele L. M., Peplinski J., Jauk D., Naim G., Shidlovsky N., Cohen A., Bennet Y., Paschold L., Dumitru C. A., Obermüller-Jevic U., Hustvedt S. O., Timmesfeld N., Gold R., Zapf A., Binder M., Sandalcioglu I. E., Mostaghim S., Przuntek H., Segal E., Yissachar N. & Haghikia A. (2026), Scientific Reports. 16, 315

Psychological stress and eating behaviors as interacting influences on patientreported disease activity in Italian patients with inflammatory bowel disease

Usta D., Acampora M., Pereira A. C., Savarese M., De Rocchis M. S., Avedano L., Leone S., Graffigna G., Salathé M., Burisch J., Halfvarsson J., Gluschak V., Segal E., Weersma R., Huber S., Skiecevičienė J. & Franke A. (2026), Scientific Reports. 16, 322

The legacy of a gentleman scientist: Pierre Hainaut

Arnoult C., Attardi L. D., Batsheva K., Blandino G., Burns K. H., Del Sal G., Kirsch D. G., Lane D. P., Levine A. J., Lozano G., Malkin D., Melino G., Oren M., Prives C. & Schramek D. (2026), Cell Death and Differentiation. 33, 1, p. 1-2

p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism

Laue K., Pozzi S., Zerbib J., Bertolio R., Eliezer Y., Cohen-Sharir Y., Winkler T., Caputo M., Ricci A. A., Adler L., Khoury R., Longobardi G., Slutsky R., Leikin-Frenkel A. I., Ovadia S., Lange K., Rustighi A., Piazza S., Sacconi A., Magesh R. Y., Keller F. N., Berthelet J., Schäffer A., Saad R., Israeli Dangoor S., Szczepanowska K., Barshack I., Liao Y., Malitsky S., Brandis A., Broggini T., Czabanka M., Shi W., Merino D., Watson E. V., Blandino G., Erez A., Ashery-Padan R., Medyouf H., Bertero L., Del Sal G., Satchi-Fainaro R. & Ben-David U. (2026), Nature Genetics. 58, 1, p. 116-131

Inhibition of Tumor Microenvironment-Driven JAK-STAT Signaling Enhances Response to Arginine Deprivation Therapy in Triple-Negative Breast Cancer

Tishler H., Ziman S., Cheng K., Wang K., Sanghvi N., Adler L., Stelzer G., Maniriho H., Dassa B., Bab-Dinitz E., Levi M., Galai S., Goldman O., Ariav Y., Darzi N., Ezagouri S., Nimni N., Rosenfeld N., Rotkopf R., Brandis A., Mehlman T., Oren R., Zerbib M., Kuznetsov Y., Donzelli S., Blandino G., Seger R., Ruppin E. & Erez A. (2026), Cells. 15, 1, 25

Temporal tissue dynamics from a spatial snapshot

Somer J., Mannor S. & Alon U. (2026), Nature

2025

Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation

Sagie S., Babu T., Weller C., Tabachnik C., Livneh I., Quast N. P., Gumpert N., Shomuradova A., Raybould M. I., Levy R., Malko D., Alfia A., Ben Lulu T., Alon M., Herrera F., Kutuzov M., Zerbib M., Greenberg P., Wasserman-Bartov T., Benedek G., Levin Y., Stossel C., Kamer I., Golan T., Oren R., Shmueli M., Bartok O., Bar J., Cohen J., Dushek O., Deane C. M. & Samuels Y. (2025), Cell Reports Medicine. 6, 12, 102506

HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

Chemla Y., Itzhaki O., Melamed S., Weller C., Sade Y., Manich P., Reshef K., Xenidis N., Maliah A., Levy G., Parikh R., Bartok O., Levy O., Tal I., Aziel G., Nissani A., Yunger S., Likonen D., Kliminsky V., Golan T., Capron C., Ace V., Levy R., Rasoulouniriana D., Eyal Z., Barzilay Y., Balaban R., Khateeb A., Khosravi R., Grau A., Ziv T., Greenberg P., Netanely D., Vaknin H., Wu X., Amitay Y., Brenner R., Martínez Gómez J. M., Hershkovitz D., Yardeni T., Zemser-Werner V., Kobiler O., Friedmann Y., Bassan D., Shamir R., Eisenbach L., Santana-Magal N., Milyavsky M., Eisenberg G., Keren L., Cohen M., Gur D., Barak B., Lotem M., Sprinzak D., Greenberger S., Fisher D., Besser M. J., Khaled M., Close P., Shapira R., Apcher S., Madi A., Levesque M. P., Rapino F., Carmi Y., Parikh S., Samuels Y. & Levy C. (2025), Cell. 189, 1, p. 233-251.e29

HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer

Gumpert N., Sagie S., Arnedo-Pac C., Babu T., Weller C., Gonzalez-Perez A., Wang Y., Michel Todó L., Levy R., Chen X., Greenberg P., Dayan-Rubinov M., Yakubovich E., Wasserman-Bartov T., Zerbib M., Gong J., Rebernick R. J., Oliveira Tercero A., Agundez Muriel L., Benedek G., Kedmi M., Oren R., Ben-Dor S., Levin Y., Troyanskaya O. G., Munzur A. D., Wyatt A. W., Cieslik M. P., Quigley D. A., Van Allen E. M., Anandasabapathy N., Mateo J., Yang X., Martínez-Jiménez F., Lopez-Bigas N. & Samuels Y. (2025), Cancer Discovery, p. OF1-OF20

A Drosophila screen of schizophrenia genes highlights neural and glial MMPs in neuronal remodeling

Keret S., Meltzer H., Marmor-Kollet N. & Schuldiner O. (2025), Life Science Alliance. 8, 12, e202503504

MMS22L is a novel key actor of normal and pathological erythropoiesis

Colin E., Ferrer-Vicens I., Brook D., Salma M., Andrieu-Soler C., Bayard E., Fernandes A., Brouzes C., Lefèvre C., Duval R., Dussiot M., Trovati T., Courtois G., Azouzi S., Zarhrate M., Lambilliotte A., Park S., Carpentier B., Colard M., Manceau S., Moshous D., Mayeux P., Gautier E. F., Miccio A., Soulier J., Vainchenker W., Shlush L., Da Costa L., Frayne J., Soler E., Hermine O. & Couronné L. (2025), HemaSphere. 9, 12, e70264

Dissecting endometrial cancer complexity in response to standard and targeted therapies

Vaccarella S., Bruno V., Orlandi G., Covino D. A., Frascolla C., Pulito C., Vizza R., Urbani G., Allegretti M., De Pascale V., Goeman F., Ciuffreda L., Arteni B. A. M., Di Martino S., Sacconi A., Mancini E., Bagnato A., Baiocco E., Kajal R., Vinik Y., Lev S., Fanciulli M., Vidiri A., Carosi M., Strano S., Donzelli S., Vizza E. & Blandino G. (2025), Cell Death and Disease. 16, 873

Integrated spatial proteomic analysis of breast cancer heterogeneity unravels cancer cell phenotypic plasticity

Mardamshina M., Karagach S., Mohan V., Arad G., Necula D., Golani O., Fellus-Alyagor L., Shenoy A., Krol K., Pirak D., Itzhacky N., Marin I., Shalmon B., Addadi Y., Sharan R., Gal-Yam E., Barshack I. & Geiger T. (2025), Nature Communications. 16, 10482

Single-cell transcriptomic analysis of HPV-related multiphenotypic sinonasal carcinoma uncovers MYB-HPV association

Wizel A., Spence M. D., Mints M., Britton W., Okolo O., Yu V., Cioffi I., Caruana S., Troob S. H., Faquin W. C., Lin D. T., Tirosh I., Puram S. V., Parikh A. S. & Drier Y. (2025), npj Precision Oncology. 9, 378

Unifying regulatory motifs in endocrine circuits

Raz M., Glass D. S., Milo T., Korem Kohanim Y., Karin O., Tendler A., Mayo A. & Alon U. (2025), Nature Communications. 16, 11017

Molecular Systems Biology at 20: reflecting on the past, envisioning the future

Bheda P., Hou J., Aebersold R., Alon U., Bader J. S., Bardwell L., Liu E. T., Locke J. C., Mann M., Millar A. J., Naef F., Pilpel Y., Shamir R. & Vitkup D. (2025), Molecular Systems Biology. 21, 12, p. 1667-1673

Sirt6 prevents the age-related decline of H2S through the control of one-carbon metabolism

Touitou N., Nahum L., Feldman-Trabelsi S., Avivi M. Y., Aon M. A., Naiman S., Rathaus M., Gertler A. A., Roichman A., Dvir L. B., Bernier M., Banskota N., Beck L., Nagar R., Schwartz Z., Price N. L., Harel M., Lerrer B., Ishii I., Senderowitz H., Moaddel R., Geiger T., de Cabo R. & Cohen H. Y. (2025), Proceedings of the National Academy of Sciences of the United States of America. 122, 46, e251408412

Characterization of the tumor microbiome of brain metastases and glioblastoma reveals tumor-type-specific and location-specific microbial signatures

Gigi E., Gavert N., Raijman-Nagar L., Zwang Y., Zemach H., Livyatan I., Levy-Barda A., Laviv Y., Kanner A. A., Amiel A., Siegal T., Leibovici A., Selezen I., Badran O., Zohar Y., Safadi E., Prather L. L., Helfer C. R., Castro P., Barshack I., Dadosh T., Levin-Zaidman S., Goliand I., Golani O., Horn S., Mandel J. J., Shental N., Shai A., Yust-Katz S. & Straussman R. (2025), Nature Cancer. 6, 11, p. 1761-1776

Principles of Bacteriostatic and Bactericidal Antibiotics at Subinhibitory Concentrations

Vaisbourd E., Glass D. S., Yang Y., Mayo A., Bren A. & Alon U. (2025), mBio. 16, 11, e0206625

Open problems in ageing science: a roadmap for biogerontology

Talay A., Belikov A. V., To P. K. P., Alfatemi H. H., Alon U., Deelen J., Ewald C. Y., Gems D., Gorbunova V., Gruber J., Hagg S., Hemming J., Horvath S., Kaya A., Lewis C. J., Maier A. B., Marinova M. B., Pawelec G., Peleg S., Rattan S., Scheibye-Knudsen M., Schmauck-Medina T., Saroyan V., Seluanov A., Stolzing A., Teeling E., Williams R. W., White T., Unfried M. & De Magalhaes J. P. (2025), GeroScience

A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology

Azulay N., Milo I., Bussi Y., Ben-Uri R., Haran T. K., Eldar M., Elhanani O., Harnik Y., Yakubovsky O., Nachmany I., Salame T., Wartenberg M., Bertheau P., Michonneau D., Socie G. & Keren L. (2025), Science Translational Medicine. 17, 823, eadu6032

p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer

Aylon Y., Furth N., Pirona A. C., Lavie A., Fedorova O., Hassin O., Padrão N., Steinmetz M., Sarusi-Potuguez A., Fellus-Alyagor L., Shimoni I., Dassa B., Zwart W., Shema E. & Oren M. (2025), Proceedings of the National Academy of Sciences - PNAS. 122, 44, e252264612

ProtoMol: enhancing molecular property prediction via prototype-guided multimodal learning

Wang Y., Zhang K., Huang J., Yin N., Liu S. & Segal E. (2025), Briefings in Bioinformatics. 26, 6, bbaf629

Artificial intelligence in metabolic research

Holst J. J., Scheele C., Scherer P. E., Jia W., Segal E., Slavov N., Loos R. J. F., Vahedi G., Sun L., Babu M. M., McCradden M. D. & Jacobs P. G. (2025), Nature Metabolism. 7, 11, p. 2183-2186

Evolutionarily conserved role of oxytocin in zebrafish social reward encoding

Kareklas K., Herrera-Castillo L., Levkowitz G. & Oliveira R. F. (2025), Biology Letters. 21, 11, 20250628

Vagal blockade of the brain-liver axis deters cancer-associated cachexia

Garrett A., Darzi N., Deshmukh A., Rosenfeld N., Goldman O., Adler L., Bab-Dinitz E., Singer O., Hassani Najafabadi A., Wong C. W., Bose S., Randon P. M., Bustamante F., Larios R., Brandis A., Mehlman T., Smaglo B., Chang P., Oliva J., Haymaker C., Nagawekar L., Wu S. R., Huang Y., Shen A., Vora A., Padilla J. F., Pfeffer A., Sutherland G., Starr M., Zimmers T., Zhu Y., Morizio J., Erez A. & Shen X. (2025), Cell. 188, 21, p. 6044-6063.e24

Towards a reference cell atlas of liver diversity over the human lifespan

Taylor S. A., Bader G. D., Macparland S., Mullen A. C., Andrews T., Cuenca A. G., Dasgupta R., Gehring A. J., Grun D., Guilliams M., Gulamhusein A., Henderson N. C., Hirschfield G., Huppert S. S., Itzkovitz S., Jiang Z. G., Lauer G. M., Mcgilvray I., Mysore K. R., Pirola C. J., Quon G., Rahbari M., Regev A., Ricciuto A., Scott C. L., Sharma A., Sookoian S., Tana M. M., Teichmann S. A., Vallier L., Vlachos I. S., Wang B. & Zhen M. (2025), Nature Reviews Gastroenterology and Hepatology. 23, 1, p. 97-109

IceQream: Quantitative chromosome accessibility analysis using physical TF models

Bercovich A., Lifshitz A., Eldar M., Cheng S., Stok Ranen R., Stelzer Y. & Tanay A. (2025), Nature Communications. 16, 8984

IceQream: Quantitative chromosome accessibility analysis using physical TF models

Bercovich A., Lifshitz A., Eldar M., Cheng S., Stok Ranen R., Stelzer Y. & Tanay A. (2025), Nature Communications. 16, 8984

CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging

Elyahu Y., Feygin I., Eremenko E., Pinkas N., Zemer A., Shicht A., Berner O., Avigdory-Meiri R., Nemirovsky A., Reshef K., Roitman L., Krizhanovsky V. & Monsonego A. (2025), Nature Aging. 5, 10, p. 1970-1982

Transcriptomic profiling of shed cells enables spatial mapping of cellular turnover in human organs

Barkai T., Yakubovsky O., Korem Kohanim Y., Bahar Halpern K., Shir S., Oren N., Fine M., Kelmer P., Talmon A., Israeli A., Pencovich N., Pery R., Nachmany I. & Itzkovitz S. (2025), Molecular Systems Biology. 21, 12, p. 1778-1792

Stool shed cell transcriptomics mirrors tumor biology and enables colorectal cancer diagnosis

Bahar Halpern K., Kent I., Yakubovsky O., Ben-Moshe S., Barkai T., Fine M., Novoselsky R., Israeli A., Nachmany I. & Itzkovitz S. (2025), Scientific Reports. 15, 34413

Challenges and Opportunities in Spatiotemporal Models of Mammalian Gastrulation

Rubinstein H., Mayshar Y. & Stelzer Y. (2025), Annual Review of Cell and Developmental Biology. 41, 1, p. 135-158

PNKP targeting engages the autophagic machinery through STING and STAT3 to potentiate ferroptosis and chemotherapy in TNBC

Maimon A., Puzzovio P. G., Vinik Y., Hannuna G. D., Donzelli S., Rutigliano D., Blandino G. & Lev S. (2025), Redox Biology. 86, 103775

Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements

Levy G., Rokach M., Fischer I., Kimchi-Feldhorn O., Shoob S., Bar E., Rosenberg T., Bartman J., Parnas H., Grad M., Israel-Elgali I., Sfadia G. E., Trangle S. S., Vainshtein A., Eisenbach Y. E., Jahn O., Siems S. B., Werner H. B., Shomron N., Assaf Y., Peles E., Slutsky I., Marco A. & Barak B. (2025), Nature Communications. 16, 8518

The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution

Sebé-Pedrós A., Tanay A., Lawniczak M. K., Arendt D., Aerts S., Archibald J., Arnone M. I., Blaxter M., Cleves P., Coelho S. M., Dias M., Dunn C., Elek A., Frazer J., Gabaldón T., Gillis J., Grau-Bové X., Guigó R., Hobert O. & Huerta-Cepas J. (2025), Nature. 645, 8082, p. 877-885

Disruption of the developmental factor Otp in the adult forebrain reveals its diverse physiological functions

Tahor M., Kuperman Y., Nahum T., Tsoory M., Bejar B., Regev E., Blechman J., Biran J., Chen A. & Levkowitz G. (2025), BioRxiv

Fibro predict a machine learning risk score for advanced liver fibrosis in the general population using Israeli electronic health records

Kalka I. N., Hazzan R., Yacovzada N. S., Igbaria S., Segal E., Weinberger A. & Neeman Z. (2025), Scientific Reports. 15, 32035

Multimodal AI correlates of glucose spikes in people with normal glucose regulation, pre-diabetes and type 2 diabetes

Carletti M., Pandit J., Gadaleta M., Chiang D., Delgado F., Quartuccio K., Fernandez B., Raygoza Garay J. A., Torkamani A., Miotto R., Rossman H., Berk B., Baca-Motes K., Kheterpal V., Segal E., Topol E. J., Ramos E. & Quer G. (2025), Nature Medicine. 31, 9, p. 3121-3127

Deep phenotyping of health-disease continuum in the Human Phenotype Project

Reicher L., Shilo S., Godneva A., Lutsker G., Zahavi L., Shoer S., Krongauz D., Rein M., Kohn S., Segev T., Schlesinger Y., Barak D., Levine Z., Keshet A., Shaulitch R., Lotan-Pompan M., Elkan M., Talmor-Barkan Y., Aviv Y., Dadiani M., Tsodyks Y., Gal-Yam E. N., Leibovitzh H., Werner L., Tzadok R., Maharshak N., Koga S., Glick-Gorman Y., Stossel C., Raitses-Gurevich M., Golan T., Dhir R., Reisner Y., Weinberger A., Rossman H., Song L., Xing E. P. & Segal E. (2025), Nature Medicine. 31, 9, p. 3191-3203

Long-term Hyperbaric Oxygen Treatment Enhances Nerve Regeneration and Remyelination in a Rat Sciatic Nerve Graft Model

Kedar D. J., Shani N., Fliss E., Bracha G., Zvi E., Rosen R., Greenberg O., Eshed Eisenbach Y., Peles E. & Gur E. (2025), Plastic and Reconstructive Surgery - Global Open. 13, 8, p. e7039

The Nodes of Ranvier: Mechanisms of Assembly and Maintenance

Rasband M. N. & Peles E. (2025), Cold Spring Harbor perspectives in biology. 17, 8, a041361

Immune surveillance of senescent cells in aging and disease

Majewska J. & Krizhanovsky V. (2025), Nature Aging. 5, p. 1415-1424

Hyperbaric Oxygen Therapy for PTSD: Threshold Effect for Sustained Symptom Improvement in a Biologically Based Treatment

Danan D., Grosskopf Y., Mayo A., Efrati S., Kutz I., Lang E., Alon U. & Doenyas-Barak K. (2025), Brain and Behavior. 15, 8, e70757

RNA editing deficiency models differential immunogenicity of pancreatic α- and β-cells

Peleg S., Zamashanski L., Belin J., Novoselsky R., Cohen-Fultheim R., Knebel U. E., Glaser B., Itzkovitz S., Kaestner K. H., Powers A. C., Levanon E. Y., Klochendler A. & Dor Y. (2025), Molecular Metabolism. 98, 102183

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing

Somech E., Halder D., Spitzer A., Barbolin C., Tyler M., Halperin R., Biton M., Tirosh A. & Tirosh I. (2025), eLife. 13, RP101153

Generative AI enables medical image segmentation in ultra low-data regimes

Zhang L., Jindal B., Alaa A., Weinreb R., Wilson D., Segal E., Zou J. & Xie P. (2025), Nature Communications. 16, 6486

Mapping circulating hematopoietic stem cells for non-invasive, blood-based diagnostics

Furer N. & Shlush L. (2025), Nature Medicine

Crohns disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset

Bourgonje A. R., Andreu-Sánchez S., Gacesa R., Innocenti G., Kalka I. N., Klompus S., Leviatan S., Schlesinger Y., Krongauz D., Weinberger A., Van Der Vegt B., Fu J., Segal E., Zhernakova A., Vogl T. & Weersma R. K. (2025), Gut. 74, 12, p. 1977-1988

From bench to business: translating academic advances into industry innovations

Abilez O. J., Javali A., Jones J., Rellán-Álvarez R., Sozzani R. & Tzahor E. (2025), Development. 152, 13, dev205007

High-Throughput Single-Cell Proteomics of In Vivo Cells

Karagach S., Smollich J., Atrakchi O., Mohan V. & Geiger T. (2025), Molecular and Cellular Proteomics. 24, 7, 101018

Baseline Characteristics of Weight-Loss Success in a Personalized Nutrition Intervention: A Secondary Analysis

Popp C. J., Wang C., Berube L., Curran M., Hu L., Pompeii M. L., Barua S., Li H., St-Jules D. E., Schoenthaler A., Segal E., Bergman M. & Sevick M. A. (2025), Nutrients. 17, 13, 2178

A reference model of circulating hematopoietic stem cells across the lifespan with applications to diagnostics

Furer N., Rappoport N., Milman O., Tavor S., Lifshitz A., Bercovich A., Ben-Kiki O., Danin A., Kedmi M., Shipony Z., Lipson D., Meiri E., Yanai G., Shapira S., Arber N., Berdichevsky S., Tyner J., Joshi S., Landau D., Ganesan S., Dusaj N., Chamely P., Kaushansky N., Chapal-Ilani N., Shamir R., Tanay A. & Shlush L. (2025), Nature Medicine. 31, 7, p. 2442-2451

A reference model of circulating hematopoietic stem cells across the lifespan with applications to diagnostics

Protocol for predicting suppressors of cell-death pathways based on transcriptomic and vulnerability data

Vinik Y., Maimon A. & Lev S. (2025), STAR Protocols. 6, 2, 103855

The Society for Immunotherapy of Cancer Perspective on Liquid Biopsy and Radiomics-Based Technologies for Immuno-oncology Biomarker Discovery and Application

Monette A., Aguilar-Mahecha A., Altinmakas E., Angelos M. G., Assad N., Batist G., Bommareddy P. K., Bonilla D. L., Borchers C. H., Church S. E., Ciliberto G., Cogdill A. P., Fattore L., Hacohen N., Haris M., Lacasse V., Lie W. R., Mehta A., Ruella M., Sater S., Spatz A., Taouli B., Tarhoni I., Gonzalez-Kozlova E., Tirosh I., Wang X. & Gnjatic S. (2025), Clinical Cancer Research. 31, 12, p. 2278-2293

Esophageal microbiome correlates with post-esophagectomy anastomotic leak in cancer patients

Naddaf R., Shmilovich H., Carasso S., Keshet-David R., Herren R., Gefen T., Goshen-Lago T., Zwang Y., Livyatan I., Shental N., Haberfeld O., Straussman R., Markar S. R., Nilsson M., Kashtan H., Ben-Aharon I. & Geva-Zatorsky N. (2025), ESMO Gastrointestinal Oncology. 8, 100172

Curating a single-cell data atlas for a deeper understanding of intra-tumor heterogeneity

Tyler M. & Tirosh I. (2025), Nature Cancer. 6, 6, p. 922-923

Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice

Kim J., Trzebanski S., Shin S., Schori L., Frumer Friedman G. R., Ilani N. C., Kadam A., Vicario R., Aust O., Bugaeva P., Piatek S., Ismajli L. K., Hoffmann C. J., Scheller M., Boura-Halfon S., Kaushansky N., Golani O., Solomon A., Liu Z., Amann L., Böhm-Sturm P., Koch S. P., Wenger N., Ginhoux F., Prinz M., Avraham R., Harms C., Geissmann F., Müller-Tidow C., Uderhardt S., Milenkovic I., Shlush L. & Jung S. (2025), Cell Reports. 44, 5, 115609

Erratum: Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma (Cancer Cell (2021) 39(6) (779792.e11), (S1535610821002683), (10.1016/j.ccell.2021.05.002))

Hara T., Chanoch-Myers R., Mathewson N. D., Myskiw C., Atta L., Bussema L., Eichhorn S. W., Greenwald A. C., Kinker G. S., Rodman C., Gonzalez Castro L. N., Wakimoto H., Rozenblatt-Rosen O., Zhuang X., Fan J., Hunter T., Verma I. M., Wucherpfennig K. W., Regev A., Suvà M. L. & Tirosh I. (2025), Cancer Cell. 43, 6, p. 1175-1176

Characterizing the metabolome of children with growth hormone deficiency

Shilo S., Keshet A., Halloun R., Bar N., Cohen M., Gal S., Oren M., Glantz-Gashai Y., Malitsky S., Itkin M., Lotan-Pompan M., Godneva A., Weinberger A., Tiosano D. & Segal E. (2025), Journal of Pediatric Endocrinology and Metabolism. 38, 8, p. 815-823

Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimers Disease

Villacampa N., Sarlus H., Martorell P., Bhalla K., Gomez-Castro S., Vieira-Saecker A., Slutzkin I., Händler K., Venegas C., McManus R., Ulas T., Beyer M., Segal E. & Heneka M. T. (2025), ASN Neuro. 17, 1, 2506406

Translation dysregulation in cancer as a source for targetable antigens

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GD3 ganglioside checkpoints in immune surveillance of senescent cells: Immune surveillance

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Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer

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