Research in our department centers around molecular mechanisms that control different aspects of cell biology during development and disease states. Large part of the research focuses on cancer heterogeneity at both genomics, proteomics, and the cancer microbiome. We bring unique and innovative research approaches that shed light on organ function in vivo, such as heart, liver, pancreas, gut, and the nervous system. Studies at the department explore diverse cell biology topics including cell-cell communication, cytoskeletal organization; intracellular signaling; senescence, differentiation; physiology and metabolism.

Latest PUBLICATIONS

  • MMS22L is a novel key actor of normal and pathological erythropoiesis

    Colin E., Ferrer-Vicens I., Brook D., Salma M., Andrieu-Soler C., Bayard E., Fernandes A., Brouzes C., Lefèvre C., Duval R., Dussiot M., Trovati T., Courtois G., Azouzi S., Zarhrate M., Lambilliotte A., Park S., Carpentier B., Colard M., Manceau S., Moshous D., Mayeux P., Gautier E. F., Miccio A., Soulier J., Vainchenker W., Shlush L., Da Costa L., Frayne J., Soler E., Hermine O. & Couronné L. (2025), HemaSphere. 9, 12, e70264

  • Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer

    Gumpert N., Sagie S., Arnedo-Pac C., Babu T., Weller C., Gonzalez-Perez A., Wang Y., Michel Todó L., Levy R., Chen X., Greenberg P., Dayan-Rubinov M., Yakubovich E., Wasserman-Bartov T., Zerbib M., Gong J., Rebernick R. J., Oliveira Tercero A., Agundez Muriel L., Benedek G., Kedmi M., Oren R., Ben-Dor S., Levin Y., Troyanskaya O. G., Munzur A. D., Wyatt A. W., Cieslik M. P., Quigley D. A., Van Allen E. M., Anandasabapathy N., Mateo J., Yang X., Martínez-Jiménez F., Lopez-Bigas N. & Samuels Y. (2025), Cancer Discovery, p. OF1-OF20

  • Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation

    Sagie S., Babu T., Weller C., Tabachnik C., Livneh I., Quast N. P., Gumpert N., Shomuradova A., Raybould M. I., Levy R., Malko D., Alfia A., Ben Lulu T., Alon M., Herrera F., Kutuzov M., Zerbib M., Greenberg P., Wasserman-Bartov T., Benedek G., Levin Y., Stossel C., Kamer I., Golan T., Oren R., Shmueli M., Bartok O., Bar J., Cohen J., Dushek O., Deane C. M. & Samuels Y. (2025), Cell Reports Medicine. 6, 12, 102506

  • HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

    Chemla Y., Itzhaki O., Melamed S., Weller C., Sade Y., Manich P., Reshef K., Xenidis N., Maliah A., Levy G., Parikh R., Bartok O., Levy O., Tal I., Aziel G., Nissani A., Yunger S., Likonen D., Kliminsky V., Golan T., Capron C., Ace V., Levy R., Rasoulouniriana D., Eyal Z., Barzilay Y., Balaban R., Khateeb A., Khosravi R., Grau A., Ziv T., Greenberg P., Netanely D., Vaknin H., Wu X., Amitay Y., Brenner R., Martínez Gómez J. M., Hershkovitz D., Yardeni T., Zemser-Werner V., Kobiler O., Friedmann Y., Bassan D., Shamir R., Eisenbach L., Santana-Magal N., Milyavsky M., Eisenberg G., Keren L., Cohen M., Gur D., Barak B., Lotem M., Sprinzak D., Greenberger S., Fisher D., Besser M. J., Khaled M., Close P., Shapira R., Apcher S., Madi A., Levesque M. P., Rapino F., Carmi Y., Parikh S., Samuels Y. & Levy C. (2025), Cell

  • HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

    Chemla Y., Itzhaki O., Melamed S., Weller C., Sade Y., Manich P., Reshef K., Xenidis N., Maliah A., Levy G., Parikh R., Bartok O., Levy O., Tal I., Aziel G., Nissani A., Yunger S., Likonen D., Kliminsky V., Golan T., Capron C., Ace V., Levy R., Rasoulouniriana D., Eyal Z., Barzilay Y., Balaban R., Khateeb A., Khosravi R., Grau A., Ziv T., Greenberg P., Netanely D., Vaknin H., Wu X., Amitay Y., Brenner R., Martínez Gómez J. M., Hershkovitz D., Yardeni T., Zemser-Werner V., Kobiler O., Friedmann Y., Bassan D., Shamir R., Eisenbach L., Santana-Magal N., Milyavsky M., Eisenberg G., Keren L., Cohen M., Gur D., Barak B., Lotem M., Sprinzak D., Greenberger S., Fisher D., Besser M. J., Khaled M., Close P., Shapira R., Apcher S., Madi A., Levesque M. P., Rapino F., Carmi Y., Parikh S., Samuels Y. & Levy C. (2025), Cell

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  • Date: December 7, 2025

    Congratulations to Prof. Ayelet Erez

    Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award

  • Date: July 16, 2025

    Congratulations to Prof. Yonatan Stelzer

    Scientific Council Prize for Life Sciences

  • Date: July 16, 2025

    Congratulations to Prof. Liran Shlush

    Morris L. Levinson Prize in Biology